2005 R&D 100 Winner
Non-invasive, in-vivo imaging has undergone huge advancements over the past years. Following that trend is the Maestro In-Vivo Imaging System, developed by Cambridge Research and Instrumentation, Inc., Woburn, Mass.

The Maestro is a fluorescence based in-vivo imaging system which dramatically improves measurement sensitivity by using multi-spectral imaging technology. The system is primarily used for imaging fluorescently labeled animal modes of disease. In can detect multiple fluorophores in a single animal, as well as removing autofluorescence, thereby increasing the signal to noise ratio for the labeled targets.

This type of in-vivo imaging is an effective tool for assessing tumor progression, detecting physiological and pathological processes, and monitoring the physiological effects of external agents. This system can be effectively applied towards detection and imaging of anti-body based assays, molecular targeting agents, fluorescent drug pharmacokinetics, angiogenesis markers, and pH and ion-sensors.

Fluorescence based in-vivo imaging system

Cambridge Research and Instrumentation, Inc.