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ORiGAMI: Oak Ridge Graph Analytics for Medical Innovation is a novel, intelligent tool for discovering and evaluating potentially interesting associations and creating novel hypotheses in medicine. ORiGAMI helps “connect the dots” across 70 million knowledge nuggets published in 23 million papers in the medical literature. The tool, which won a 2016 R&D 100 award, works on a “Knowledge Graph” derived from SEMANTIC MEDLINE published by the National Library of Medicine integrated with scalable software that enables term-based, path-based, meta-pattern and analogy-based reasoning principles.

Since ORiGAMI is an open-access tool (using demo-interface or the API-interface), medical professionals and researchers alike are exploring clinical questions (close to 30 unique searches per day) and finding answers to questions such as "How does Nexium treat heartburn?" "What viruses have similar characteristics as Ebola?" "Is xylene carcinogenic?" "Can beta-blockers accelerate diabetic-retinopathy?" ORiGAMI’s success with medical literature has led to newer collaborations in physics, intelligence and material discovery applications.

Each year for more than 50 years, R&D Magazine has honored the 100 best innovations in research and development. We are currently accepting applications for the 2017 R&D 100 Awards. Innovators with an exceptional product developed between January 1, 2016 and March 31, 2017 should apply. Submissions close April 14, 2017

For information on the 55th Annual R&D 100 Awards and to enter visit http://www.rd100conference.com

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