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A new white paper from Decision Lens teaches how world-class innovation teams create standard frameworks to evaluate and prioritize the strategic investments that deliver the highest returns on investment, streamlining and accelerating the R&D portfolio planning process.  

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by Nils Anspach and Frank Hitzel, DME Nanotechnologie GmbH, Endré Majorovits and Fabián Pérez-Willard, Carl Zeiss Microscopy

In a new white paper from Carl Zeiss Microscopy, scientists from DME Nanotechnologie GmbH and Zeiss demonstrate the power of the AFM/SEM combination found in the Zeiss Merlin series microscopes for the analysis of helium ion beam exposed nanostructures.

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Oxford Gene Technology (OGT), a provider of genetics research and biomarker solutions to advance molecular medicine, has produced a new white paper that is designed to help researchers looking to develop next-generation sequencing strategies. It covers resequencing, methods suitability, data analysis and time and cost considerations.

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by Jim Hunter, senior project engineer; Mark Meinders, product manager; and Brian Garrett, product specialist, Labconco Corporation

HEPA filter loading can compromise a biological safety cabinet's ability to maintain proper airflow. This white paper, by Labconco Corp., will review the current technologies used by various biosafety cabinet manufacturers to monitor and maintain proper airflows as HEPA filters load.

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Characterization of the chemical composition of fibers is of high importance in both forensic science and the textile industry. As demonstrated by Bruker Optics in a recent white paper, the Fourier transform infrared (FT-IR) imaging capabilities of the LUMOS microscope, which require minimal sample preparation, are suitable for this type of analysis.

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Bruker’s LUMOS microscope is equipped with a motorized attenuated total reflectance (ATR) germanium objective that is highly suitable for analysis of dark samples without the need for preparation. In this white paper from Bruker Optics, the analysis of dark streaks on a polycarbonate sample is simplified through the use of automation procedures.

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As electronic devices get smaller, they are becoming more vulnerable to contamination through the presence of impurities. Using a Fourier transform infrared (FT-IR) microscope such as Bruker Optics’ LUMOS, contaminations in the low micrometer range can be identified. In this white paper, Bruker demonstrates how FT-IR can be used to determine surface contamination on the soldering contact of a surface mounted device.

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Traditionally, content uniformity analysis for tablets has been performed off-line by liquid chromatography. Performed in batches, this approach is time-consuming. A new spectroscopy-based system called TANDEM, as detailed by Bruker Optics in a white paper, combines Bruker’s Matrix Fourier transform near-infrared spectrometer with a Dr. Schleuniger Pharmatron 10X conventional tablet tester to enable rapid, on-line, non-destructive tablet content uniformity characterization along with moisture and excipient analysis.

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Modern forensics demands solutions that can analyze wide variety of materials and samples, both organic and inorganic. In a white paper, Bruker Optics discusses the ability of its Hyperion infrared microscope and Senterra Raman microscope to effectively analysis paint chips, fibers, drugs, residues, and other evidence. The strengths of each instrument, with regard to spectroscopic and optical capabilities, are described.

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The dietary intake of pigs greatly affects the composition of pork fat, which is found in all processed pork meat products. One way to monitor pork fat firmness, a value that can easily be affected by certain types of common feed, is to measure the iodine value (IV). Bruker Optics has published a white paper that details how IV can be obtained quickly and accurately with a Tango Fourier transform near-infrared (FT-NIR) spectrometer.

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Supplying both spectral and spatial information, hyperspectral imagers are useful for obtaining data over a wide area, such the dispersion field of a gas cloud. Bruker Optics discusses its new HI 90 Hyperspectral Imaging System in a white paper that demonstrates the effectiveness of an active-alignment plane mirror interferometer that is an improvement over cube-corner-based systems.

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Because of its convenience and speed, scientific characterization of solids is often performed by Fourier transform infrared (FT-IR) spectroscopy unit with an attenuated total reflection (ATR) module. A recent white paper published by Bruker Optics describes how its new platinum diamond ATR module in an ALPHA FT-IR spectrometer can be used to perform an analysis on polyethylene terephthalate, a thermoplastic commonly used as a container for foods or beverages.

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Attenuated total reflection (ATR) analysis identifies liquids or solids based on the attenuation of a detected infrared (IR) light wave as it is reflected inside a crystal on which the sample is placed. As a non-destructive and preparation-free method, it has become crucial to IR detection applications and is much less labor-intensive than the usual method of preparing liquid cells or potassium bromide pellets. A white paper from Bruker Optics discusses why ATR is so valuable, and how it is employed in Bruker's spectroscopic instrumentation.

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In a white paper, Bruker Optics discusses a new analytical method that can save both time and a potentially expensive transport procedure. By law, waste water produced on off-shore oil platforms must conform to hydrocarbon content parameters. Previously, the only recognized way to obtain this data was off-site gas chromatography using flammable pentane. A Bruker Optics ALPHA Fourier transform infrared spectrometer has been used to perform the same analysis using a simpler extraction method.

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International NIR Global Operating Technologies, or INGOT, is a set of universal near-infrared (NIR) calibrations available for various applications in the flour and milling industry, as developed from thousands of samples by NIR calibration developers Aunir and CRA-W. A recent Bruker Optics white paper breaks down the available parameters that can be analyzed with Fourier transform NIR (FT-NIR) spectrometers, such as Bruker Optic's series MPA and Matrix-I.

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Before Fourier transform infrared (FT-NIR) spectroscopy could be brought into on-line manufacturing process analysis, development of new high-temperature and high-pressure probes had to be invented. Bruker Optics' recent white paper discusses how FT-NIR can be integrated into a polymer application such as the simultaneous monitoring of density and melt flow index of polyethylene.

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