Researchers at Yale School of Medicine have pinpointed a mechanism in part of the brain that is key to sensing glucose levels in the blood, linking it to both type 1 and type 2 diabetes. The findings are published in the Proceedings of the National Academies of Sciences.
Imagine you're fighting for your life but no matter how hard you hit, your opponent won't go down. The same can be said of highly treatment-resistant cancers, such as head and neck cancer, where during radiation and chemotherapy some cancer cells repair themselves, survive and thrive. Head and neck cancer is the sixth most common cancer in the world, but the late detection and treatment resistance result in a high mortality rate.
Soon, protection from HIV infection could be as simple as inserting a medicated, disappearing fabric minutes before having sex. Univ. of Washington bioengineers have discovered a potentially faster way to deliver a topical drug that protects women from contracting HIV. Their method spins the drug into silk-like fibers that quickly dissolve when in contact with moisture, releasing high doses of the drug.
As the climate warms and sea ice retreats, the North is changing. An ice-covered expanse now has a season of increasingly open water that is predicted to extend across the whole Arctic Ocean before the middle of this century. Storms thus have the potential to create Arctic swell. A Univ. of Washington researcher made the first study of waves in the middle of the Arctic Ocean, and detected house-sized waves during a September 2012 storm.
Tough, ultra-light foam of atom-thick sheets can be made to any size and shape through a chemical process invented at Rice Univ. In microscopic images, the foam dubbed “GO-0.5BN” looks like a nanoscale building, with floors and walls that reinforce each other. The structure consists of a pair of 2-D materials: floors and walls of graphene oxide that self-assemble with the assistance of hexagonal boron nitride platelets.
A team of researchers has created a new way of manufacturing microstructured surfaces that have novel 3-D textures. These surfaces, made by self-assembly of carbon nanotubes, could exhibit a variety of useful properties—including controllable mechanical stiffness and strength, or the ability to repel water in a certain direction.
A new stem cell discovery might one day lead to a more streamlined process for obtaining stem cells, which in turn could be used in the development of replacement tissue for failing body parts, according to Univ. of California, San Francisco scientists who reported the findings in Cell.
Fifteen years ago, Massachusetts Institute of Technology professor John Essigmann and colleagues from the Univ. of Washington had a novel idea for an HIV drug. They thought if they could induce the virus to mutate uncontrollably, they could force it to weaken and eventually die out—a strategy that our immune system uses against many viruses.
Some chemical conversions are harder than others. Refining natural gas into an easy-to-transport, easy-to-store liquid alcohol has so far been a logistic and economic challenge. But now, a new material, designed and patented by researchers at Lawrence Berkeley National Laboratory, is making this process a little easier.
Rice Univ. researchers are using magnetic beads and DNA “springs” to create chains of varying flexibility that can be used as microscale models for polymer macromolecules. The experiment is visual proof that “bead-spring” polymers, introduced as theory in the 1950s, can be made as stiff or as flexible as required and should be of interest to materials scientists who study the basic physics of polymers.
A team of international researchers has discovered a new type of cool burning flames that could lead to cleaner, more efficient engines for cars. The discovery was made during a series of experiments on the International Space Station by a team led by Forman Williams, a professor of mechanical and aerospace engineering at the Univ. of California, San Diego.
Lithium (Li)-ion batteries power almost all of the portable electronic devices that we use every day, including smartphones, cameras, toys and even electric cars. Researchers across the globe are working to find materials that will lead to safe, cheap, long-lasting and powerful Li-ion batteries.
A new method of building materials using light, developed by researchers at the Univ. of Cambridge, could one day enable technologies that are often considered the realm of science fiction. Although cloaked starships won’t be a reality for quite some time, the technique which researchers have developed for constructing materials with building blocks a few nanometers across can be used to control the way that light flies through them.
The magnets cluttering the face of your refrigerator may one day be used as cooling agents, according to a new theory. The theory describes the motion of magnons. In addition to magnetic moments, magnons also conduct heat; from their equations, the researchers found that when exposed to a magnetic field gradient, magnons may be driven to move from one end of a magnet to another, carrying heat with them and producing a cooling effect.
A novel combination of microscopy and data processing has given researchers at Oak Ridge National Laboratory (ORNL) an unprecedented look at the surface of a material known for its unusual physical and electrochemical properties. The research team led by ORNL’s Zheng Gai examined how oxygen affects the surface of a perovskite manganite, a complex material that exhibits dramatic magnetic and electronic behavior.
It’s an all-too familiar scenario for many people. You sprain your ankle or twist your knee. If you’re an adult, the initial pain is followed by a long road of recovery, with no promise that the torn ligament or tendon will ever regain its full strength. That’s because tendon and ligament cells in adults produce little collagen, the fibrous protein that is used to build new tendon and ligament tissue.
Much artificial intelligence research addresses the problem of making predictions based on large data sets. An obvious example is the recommendation engines at retail sites like Amazon and Netflix. But some types of data are harder to collect than online click histories. And in other applications there may just not be enough time to crunch all the available data.
Researchers have discovered a previously unknown mechanism for wear in metals: a swirling, fluid-like microscopic behavior in a solid piece of metal sliding over another. The findings could be used to improve the durability of metal parts in numerous applications.
The drought that has the entire country in its grip is affecting more than the color of people’s lawns. It may also be responsible for the proliferation of a heat-loving amoeba commonly found in warm freshwater bodies, such as lakes, rivers and hot springs, which the drought has made warmer than usual this year.
Researchers from NIST and California Institute of Technology (Caltech) have demonstrated a new design for an atomic clock that is based on a chip-scale frequency comb, or a microcomb. The microcomb clock, featured in Optica, is the first demonstration of all-optical control of the microcomb, and its accurate conversion of optical frequencies to lower microwave frequencies.
Fragile X syndrome (FXS) is a genetic disorder that causes obsessive compulsive and repetitive behaviors, and other behaviors on the autistic spectrum, as well as cognitive deficits. It’s the most common inherited cause of mental impairment and the most common cause of autism. Now biomedical scientists at the Univ. of California, Riverside have published a study that sheds light on the cause of autistic behaviors in FXS.
Scientists at SLAC National Accelerator Laboratory have invented a customizable chemical etching process that can be used to manufacture high-performance focusing devices for the brightest x-ray sources on the planet, as well as to make other nanoscale structures such as biosensors and battery electrodes.
MIT Lincoln Laboratory spinout TeraDiode is commercializing a multi-kilowatt diode laser system that’s bright enough to cut and weld through a half-inch of steel, and at greater efficiencies than today’s industrial lasers. The new system is based on a wavelength beam-combining laser diode design that won an R&D 100 Award in 2012. It combines multiple beams into a single output ray, allowing for a power boost without efficiency loss.
A team of Dartmouth scientists and their colleagues have devised a breakthrough laser that uses a single artificial atom to generate and emit particles of light—and may play a crucial role in the development of quantum computers, which are predicted to eventually outperform even today’s most powerful supercomputers.
A research team from NIST, working with the Cleveland Clinic, has demonstrated a dramatically improved technique for analyzing biological cells and tissues based on characteristic molecular vibration "signatures." The new NIST technique is an advanced form of the widely used spontaneous Raman spectroscopy, but one that delivers signals that are 10,000 times stronger than obtained from spontaneous Raman scattering.