A study shows, for the first time, that x-ray lasers can be used to generate a complete 3-D model of a protein without any prior knowledge of its structure. An international team of researchers working at the SLAC National Accelerator Laboratory produced from scratch an accurate model of lysozyme, a well-studied enzyme found in egg whites, using the Linac Coherent Light Source x-ray laser and sophisticated computer analysis tools.
Massachusetts Institute of Technology chemical engineers have developed a novel way to generate nanoparticles that can recognize specific molecules, opening up a new approach to building durable sensors for many different compounds, among other applications. To create these “synthetic antibodies,” the researchers used carbon nanotubes.
Biologists at Brown Univ. have found a way to measure the effects of aging by watching the ebb and flow of chromatin, a structure along strands of DNA that either silences or permits gene expression. In several newly published experiments they show that gene silencing via chromatin in fruit flies declines with age.
A single layer of tin atoms could be the world’s first material to conduct electricity with 100% efficiency at the temperatures that computer chips operate, according to a team of theoretical physicists led by researchers from SLAC National Accelerator Laboratory and Stanford Univ.
In our universe there are particle accelerators 40 million times more powerful than the Large Hadron Collider at CERN. Scientists don’t know what these cosmic accelerators are or where they are located, but new results being reported from IceCube, the neutrino observatory buried at the South Pole, may show the way. These new results should also erase any doubts as to IceCube’s ability to deliver on its promise.
Researchers at Oak Ridge National Laboratory are working with aircraft makers to determine energy savings through the use of additive manufacturing, also known as 3-D printing. The research team is printing airplane parts to show additive manufacturing’s potential as a technology that should be considered foundational to processes seeking more energy efficiency.
Those who study hydrophobic materials are familiar with a theoretical limit on the time it takes for a water droplet to bounce away from such a surface. But Massachusetts Institute of Technology researchers have now found a way to burst through that perceived barrier, reducing the contact time by at least 40%.
Scientists have long known that phosphorus fuels growth of algae in lakes and streams. Wisconsin Sea Grant researchers have found that nitrogen levels are a factor in whether or not these algae—specifically, blue-green algae—produce toxins. The findings, published in PLOS ONE have parts of the scientific community buzzing.
Organic solar cells have long been touted as lightweight, low-cost alternatives to rigid solar panels made of silicon. Dramatic improvements in the efficiency of organic photovoltaics have been made in recent years, yet the fundamental question of how these devices convert sunlight into electricity is still hotly debated. Now a Stanford Univ. research team is weighing in on the controversy.
Researchers at Lawrence Berkeley National Laboratory have demonstrated in the laboratory a lithium-sulfur battery that has more than twice the specific energy of lithium-ion batteries, and that lasts for more than 1,500 cycles of charge-discharge with minimal decay of the battery’s capacity. This is the longest cycle life reported so far for any lithium-sulfur battery.
A Univ. of Connecticut research team has found a way to stabilize hemoglobin, the oxygen carrier protein in the blood, a discovery that could lead to the development of stable vaccines and affordable artificial blood substitutes. The team’s approach involves wrapping the polymer poly(acrylic acid) around hemoglobin, protecting it from the intense heat used in sterilization and allowing it to maintain its biological function.
Understanding superconductivity has proved to be one of the most persistent problems in modern physics. Scientists have struggled for decades to develop a cohesive theory of superconductivity, largely spurred by the game-changing prospect of creating a superconductor that works at room temperature, but it has proved to be a tremendous tangle of complex physics.
Diseases affecting the kidneys represent a major and unsolved health issue worldwide. The kidneys rarely recover function once they are damaged by disease, highlighting the urgent need for better knowledge of kidney development and physiology. Now, a team of researchers has developed a novel platform to study kidney diseases, opening new avenues for the future application of regenerative medicine strategies to help restore kidney function.
In developing nations, rural areas and even one's own home, limited access to expensive equipment and trained medical professionals can impede the diagnosis and treatment of disease. Many qualitative tests that provide a simple "yes" or "no" answer have been optimized for use in these resource-limited settings. But few quantitative tests can be done outside of a laboratory or clinical setting.
The doctor isn't in, but he can still see you now. Remote presence robots are allowing physicians to "beam" themselves into hospitals to diagnose patients and offer medical advice during emergencies. A growing number of hospitals in California and other states are using telepresence robots to expand access to medical specialists, especially in rural areas where there's a shortage of doctors.
Sometimes big change comes from small beginnings. That’s especially true in the research of Anatoly Frenkel, a prof. of physics at Yeshiva Univ., who is working to reinvent the way we use and produce energy by unlocking the potential of some of the world’s tiniest structures: nanoparticles.
The decades-long effort to create practical superconductors moved a step forward with the discovery at Rice Univ. that two distinctly different iron-based compounds share common mechanisms for moving electrons. Samples from two classes of iron-based superconductors, pnictides and chalcogenides, employ similar coupling between electrons in their superconducting state.
In deciding how best to meet the world’s growing needs for energy, the answers depend crucially on how the question is framed. Looking for the most cost-effective path provides one set of answers; including the need to curtail greenhouse gas emissions gives a different picture. Adding the need to address looming shortages of fresh water, it turns out, leads to a very different set of choices.
About half of all cancer patients have a mutation in a gene called p53, which allows tumors to survive and continue growing even after chemotherapy severely damages their DNA. A new study from Massachusetts Institute of Technology biologists has found that tumor cells with mutated p53 can be made much more vulnerable to chemotherapy by blocking another gene called MK2.
Researchers from North Carolina State Univ. have developed new technology and techniques for transmitting power wirelessly from a stationary source to a mobile receiver—moving engineers closer to their goal of creating highway “stations” that can recharge electric vehicles wirelessly as the vehicles drive by.
It may sound like chasing rainbows: Detecting flashes of light and energy that are invisible to the human eye and last only for a trillionth of an eye-blink. These flashes hold clues to the nature of exotic subatomic particles, important biological proteins and massive space objects alike.To reveal new details about science at these extremes, a team of scientists is designing intricate signal-processing chips known as ASICs.
When you squeeze atoms, you don’t get atom juice. You get magnets. According to a new theory by Rice Univ. scientists, imperfections in certain 2-D materials create the conditions by which nanoscale magnetic fields arise. Calculations by the laboratory of Rice theoretical physicist Boris Yakobson show these imperfections, called grain boundaries, in 2-D semiconducting materials known as dichalcogenides can be magnetic.
A team of scientists reports that a small-molecule compound showed significant success in controlling the infectivity and spread of three polyomaviruses in human cell cultures. To date there has been no medicine approved to treat such viruses, which prey on transplant recipients, people with HIV and others whose immune systems have been weakened.
Researchers at Rice Univ., Baylor College of Medicine and the Univ. of Texas at Austin are working together to create new statistical tools that can find clues about cancer that are hidden like needles in enormous haystacks of raw data.
A class of drugs used to treat parasitic infections such as malaria may also be useful in treating cancers and immune-related diseases, a new Washington State Univ.-led study has found. Researchers discovered that simple modifications to the drug furamidine have a major impact on its ability to affect specific human proteins involved in the on-off switches of certain genes.