Samples are precious resources and integral to the research process. The information derived from them is dependent on their quality, integrity and consistency. And, many samples represent a scientist’s investment in and trust of the biomedical research process. Yet, it is not unusual for samples to go missing, to find that their labels have fallen off or that they have become unusable.
Sandia National Laboratories researchers Jim Martin and Kyle Solis have what Martin calls “a devil of a problem.” They’ve discovered how to harness magnetic fields to create vigorous, organized fluid flows in particle suspensions. The magnetically stimulated flows offer an alternative when heat transfer is difficult because they overcome natural convection limits.
Photovoltaic spray paint could coat the windows and walls of the future if scientists are successful in developing low-cost, flexible solar cells based on organic polymers. Scientists at Oak Ridge National Laboratory recently discovered an unanticipated factor in the performance of polymer-based solar devices that gives new insight on how these materials form and function.
Artificial photosynthesis, in which we emulate the process used by nature to capture energy from the sun and convert it into electrochemical energy, is expected to be a major asset in any sustainable energy portfolio for the future. Artificial photosynthesis offers the promise of producing liquid fuels that are renewable and can be used without exacerbating global climate change.
Rice Univ. researchers have developed a theoretical approach to analyze the process by which protein building blocks form the biopolymer skeletons of living cells. The cytoskeleton, made of fibers and microtubules, gives a cell its shape and provides the “roads” along which proteins and other cargoes travel.
Massachusetts Institute of Technology chemists have devised a way to trap carbon dioxide and transform it into useful organic compounds, using a simple metal complex. More work is needed to understand and optimize the reaction, but one day this approach could offer an easy and inexpensive way to recapture some of the carbon dioxide emitted by vehicles and power plants.
Finding treatments for advanced stage cancer isn’t easy. Therefore, early detection methods are paramount in the fight against the disease. Motivated by the opportunity to intervene as early as possible in the course of cancer, Dr. Muneesh Tewari, a Univ. of Michigan researcher, has been studying the diagnostic potential of blood-based biomarkers.
Gathering all analytical data from different techniques for the same sample isn’t always an easy and routine task. This problem is amplified in high-throughput environments based on sheer volume alone. Review and analysis of information can be time consuming, leading to delays in decision-making that have detrimental effects on productivity and the speed of project completion.
Before doctors like Matthias Kretzler can begin using the results of molecular research to treat patients, they need science to find an effective way to match genes with the specific cells involved in disease. As Kretzler explains, finding that link would eventually let physicians create far more effective diagnostic tools and treatments.
Univ. of Washington computer scientists have built a low-cost gesture recognition system that runs without batteries and lets users control their electronic devices hidden from sight with simple hand movements. The prototype, called “AllSee,” uses existing TV signals as both a power source and the means for detecting a user’s gesture command.
In its 48th year, the Laboratory of the Year Awards continue to recognize excellence in research laboratory design, planning and construction. Judging for this year’s competition took place on Thursday, February 20th and was conducted by a blue-ribbon panel of laboratory architects, engineers, equipment manufacturers, researchers and the editors of R&D Magazine and Laboratory Design Newsletter.
A DNA test of a pregnant woman's blood is more accurate than current methods of screening for Down syndrome and other common disorders, new research finds. If other studies bear this out, it could transform prenatal care by giving a more reliable, non-invasive way to detect these problems very early in pregnancy.
JILA physicists used an ultrafast laser and help from German theorists to discover a new semiconductor quasiparticle, a handful of smaller particles that briefly condense into a liquid-like droplet. Quasiparticles are composites of smaller particles that can be created inside solid materials and act together in a predictable way.
Using an inexpensive 3-D printer, biomedical engineers have developed a custom-fitted, implantable device with embedded sensors that could transform treatment and prediction of cardiac disorders. An international team has created a 3-D elastic membrane made of a soft, flexible, silicon material that is precisely shaped to match the heart’s epicardium, or the outer layer of the wall of the heart.
After having recently discovered a new way to propagate multiple beams of light through a single strand of optical fiber, engineers at the Univ. of Wisconsin-Milwaukee now have found that their novel fiber architecture can transmit images with a quality that is comparable or better than the current commercial endoscopy imaging fibers.
Researchers from North Carolina State Univ. have developed a superabsorbing design that may significantly improve the light absorption efficiency of thin-film solar cells and drive down manufacturing costs. The superabsorbing design could decrease the thickness of the semiconductor materials used in thin-film solar cells by more than one order of magnitude without compromising the capability of solar light absorption.
Delivering drugs into the brain to treat neurological diseases and disorders has been a challenge. The current best and easiest way to get drugs anywhere in the body is to take them orally or to administer them intravenously. But the challenges for these routes of drug delivery for targets in the brain are multiple.
Every second, your computer must process billions of computational steps to produce even the simplest outputs. Imagine if every one of those steps could be made just a tiny bit more efficient. A Northeastern Univ. team has developed a series of novel devices that do just that. The team combined their expertise to unearth a physical phenomenon that could usher in a new wave of highly efficient electronics.
Researchers at Argonne National Laboratory in collaboration with scientists at Northwestern Univ. are the first to grow graphene on silver which, until now, posed a major challenge to many in the field. Part of the issue has to do with the properties of silver, the other involves the process by which graphene is grown.
Mottronics is a term seemingly destined to become familiar to aficionados of electronic gadgets. Named for the Nobel laureate Nevill Francis Mott, Mottronics involve materials that can be induced to transition between electrically conductive and insulating phases. If these phase transitions can be controlled, Mott materials hold promise for future transistors and memories that feature higher energy efficiencies and faster switching speeds.
If a driver is traveling to New York City, I-95 might be their route of choice. But they could also take I-78, I-87 or any number of alternate routes. Most cancers begin similarly, with many possible routes to the same disease. A new study found evidence that assessing the route to cancer on a case-by-case basis might make more sense than basing a patient’s cancer treatment on commonly disrupted genes and pathways.
Researchers have devised a way of making tiny holes of controllable size in sheets of graphene, a development that could lead to ultra-thin filters for improved desalination or water purification. The team of researchers succeeded in creating subnanoscale pores in a sheet of the one-atom-thick material, which is one of the strongest materials known.
Researchers from NIST and the FDA have demonstrated that they can make sensitive chemical analyses of minute samples of nanoparticles by, essentially, roasting them on top of a quartz crystal. The NIST-developed technique, "microscale thermogravimetric analysis," holds promise for studying nanomaterials in biology and the environment, where sample sizes often are quite small and larger-scale analysis won't work.
Volcanic eruptions in the early part of the 21st century have cooled the planet, according to a study led by Lawrence Livermore National Laboratory. This cooling partly offset the warming produced by greenhouse gases. Despite continuing increases in atmospheric levels of greenhouse gases, and in the total heat content of the ocean, global-mean temperatures at the surface of the planet have shown relatively little warming since 1998.
Engineers like to make things that work. And if one wants to make something work using nanoscale components, the size of proteins, antibodies and viruses, mimicking the behavior of cells is a good place to start since cells carry an enormous amount of information in a very tiny packet.