Many vaccines consist of a killed or disabled version of a virus. However, for certain diseases, this type of vaccine is ineffective, or just too risky. An alternative, safer approach is a vaccine made of small fragments of proteins produced by a disease-causing virus or bacterium. This has worked for some diseases, but in many cases these vaccines don’t provoke a strong enough response. Until now.
The first thorough comparison of evidence for natural gas system leaks confirms that organizations including the Environmental Protection Agency (EPA) have underestimated U.S. methane emissions generally, as well as those from the natural gas industry specifically.
Researchers have formed the first high-definition picture of the Cas9 complex, a key part of the CRISPR-Cas system used by scientists as a genome-editing tool to silence genes and probe the biology of cells. Their findingsare expected to help researchers refine and further engineer the tool to accelerate genomic research and bring the technology closer to use in the treatment of human genetic disease.
Ignition has long been considered the "holy grail" of inertial confinement fusion science. A key step along the path to ignition is to have "fuel gains" greater than unity, where the energy generated through fusion reactions exceeds the amount of energy deposited into the fusion fuel. Though ignition remains the ultimate goal, the milestone of achieving fuel gains greater than one has been reached for the first time ever on any facility.
It's not quite Star Trek communications—yet. But long-distance communications in space may be easier now that researchers have designed a clever detector array that can extract more information than usual from single particles of light. Described in a new paper, the NIST/JPL array-on-a-chip easily identifies the position of the exact detector in a multi-detector system that absorbs an incoming infrared light particle, or photon.
Science and Engineering Indicators (SEI) is first and foremost a volume of record comprising the major high-quality quantitative data on the U.S. and international science and engineering enterprise. SEI is factual and policy neutral. It doesn’t offer policy options, and it doesn’t make policy recommendations.
Methane, a key greenhouse gas, has more than doubled in volume in Earth's atmosphere since 1750. Its increase is believed to be a leading contributor to climate change. But where is the methane coming from? Research by a California Institute of Technology atmospheric chemist suggests that losses of natural gas—our "cleanest" fossil fuel—into the atmosphere may be a larger source than previously recognized.
On the eve of the 25th World AIDS Day (December 2014), President Barack Obama expressed hope to our nation, proclaiming that an “AIDS-free generation is within our reach.” During his speech, Obama expressed how our nation has made significant strides toward strengthening scientific investments, building effective HIV/AIDS education and prevention programs and bringing together public and private stakeholders.
Seeking a solution to decoherence, scientists have developed a strategy of linking quantum bits together into voting blocks, a strategy that significantly boosts their accuracy. In a recently published paper, the team found that their method results in at least a five-fold increase in the probability of reaching the correct answer when the processor solves the largest problems tested by the researcher, involving hundreds of qubits.
Topological insulators have been of great interest to physicists in recent years because of unusual properties that may provide insights into quantum physics. But most analysis of such materials has had to rely on highly simplified models. Now, a team of researchers at Massachusetts Institute of Technology has performed a more detailed analysis that hints at the existence of six new kinds of topological insulators.
Working on the cutting edge of a newly emerging area of solar-cell research, Univ. of California, Los Angeles engineers have invented a new process for manufacturing highly efficient photovoltaic materials that shows promise for low-cost industrial production. The new process uses so-called perovskite materials, which in the past few years have significantly advanced scientists' efforts to create the next generation of solar cells.
We all learn in high school science about the dual nature of light—that it exists as both waves and quantum particles called photons. It’s this duality of light that enables the coherent transport of photons in lasers. Sound at the atomic-scale has the same dual nature, existing as both waves and quasi-particles known as phonons. Does this duality allow for phonon-based lasers?
Using electrons more like photons could provide the foundation for a new type of electronic device that would capitalize on the ability of graphene to carry electrons with almost no resistance even at room temperature—a property known as ballistic transport. Research reported that electrical resistance in nanoribbons of epitaxial graphene changes in discrete steps following quantum mechanical principles.
Trying to find new materials, to improve the performance of anything from microchips to car bodies, has always been a process of trial and error. Massachusetts Institute of Technology materials scientist Gerbrand Ceder likens it to setting out from Boston for California, with neither a map nor a navigation system—and on foot.
Gasoline-like fuels can be made from cellulosic materials such as farm and forestry waste using a new process invented by chemists at the Univ. of California, Davis. The process could open up new markets for plant-based fuels, beyond existing diesel substitutes.
Perfect sheets of diamond a few atoms thick appear to be possible even without the big squeeze that makes natural gems. Scientists have speculated about it and a few laboratories have even seen signs of what they call diamane, an extremely thin film of diamond that has all of diamond’s superior semiconducting and thermal properties.
The same physics that gives tornadoes their ferocious stability lies at the heart of new Univ. of Washington research, and could lead to a better understanding of nuclear dynamics in studying fission, superconductors and the workings of neutron stars. The work seeks to clarify what Massachusetts Institute of Technology researchers witnessed when in 2013 they named a mysterious phenomenon.
Chances are you won’t know you’ve got a staph infection until the test results come in, days after the symptoms first appear. But what if your physician could identify the infection much more quickly and without having to take a biopsy and ship it off for analysis? Researchers at the Univ. of Iowa may have found a way.
The human intestinal tract, or gut, is best known for its role in digestion. But this collection of organs also plays a prominent role in the immune system. In fact, it is one of the first parts of the body that is attacked in the early stages of an HIV infection. Knowing how the virus infects cells and accumulates in this area is critical to developing new therapies for the over 33 million people worldwide living with HIV.
Researchers from North Carolina State Univ. have developed a de facto antibiotic “smart bomb” that can identify specific strains of bacteria and sever their DNA, eliminating the infection. The technique offers a potential approach to treat infections by multi-drug resistant bacteria.
A central question has been answered regarding a protein that plays an essential role in the bacterial immune system and is fast becoming a valuable tool for genetic engineering. A team of researchers has determined how the bacterial enzyme known as Cas9, guided by RNA, is able to identify and degrade foreign DNA during viral infections, as well as induce site-specific genetic changes in animal and plant cells.
Millions of people each year remove wrinkles, soften creases and plump up their lips by injecting a gel-like material into their facial tissue. These cosmetic procedures are sometimes called “liquid facelifts” and are said to be minimally invasive. It’s rare, but sometimes things go wrong. In a matter of minutes, patients’ skin can turn red or blotchy white and the injected area becomes painful.
Nearly 30 years after the discovery of high-temperature superconductivity, many questions remain, but an Oak Ridge National Laboratory team is providing insight that could lead to better superconductors. Their work examines the role of chemical dopants, which are essential to creating high-temperature superconductors.
Soil scientists at Abertay Univ. are using 3-D printing technology to find out, for the very first time, exactly what is going on in the world beneath our feet. In the same way that ecologists study the interactions of living organisms above ground, Prof.Wilfred Otten and researchers at the university’s SIMBIOS Centre are taking advantage of the new technology to do the same below ground.
Do scientific papers written by well-known scholars get more attention than they otherwise would receive because of their authors’ high profiles? A new study co-authored by an Massachusetts Institute of Technology economist reports that high-status authorship does increase how frequently papers are cited in the life sciences—but finds some subtle twists in how this happens.