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The Lead

Cell’s skeleton is never still

November 24, 2014 11:23 am | by Mike Williams, Rice Univ. | News | Comments

New computer models that show how microtubules age are the first to match experimental results and help explain the dynamic processes behind an essential component of every living cell, according to Rice Univ. scientists. The results could help scientists fine-tune medications that manipulate microtubules to treat cancer and other diseases. 

Nanoparticles infiltrate, kill cancer cells from within

November 24, 2014 11:06 am | by Melanie Titanic-Schefft, Univ. of Cincinnati | News | Comments

Conventional treatment seeks to eradicate cancer cells by drugs and therapy delivered from...

Scientists do glass a solid

November 24, 2014 10:52 am | by New York Univ. | News | Comments

How does glass transition from a liquid to its familiar solid state? How does this common...

Life’s extremists may be an untapped source of antibacterial drugs

November 24, 2014 9:29 am | by David Salisbury, Vanderbilt Univ. | News | Comments

One of the most mysterious forms of life may turn out to be a rich and untapped source of...

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Researchers study impact of power prosthetic failures on amputees

November 24, 2014 8:43 am | by Matt Shipman, News Services, North Carolina State Univ. | Videos | Comments

Powered lower limb prosthetics hold promise for improving the mobility of amputees, but errors in the technology may also cause some users to stumble or fall. New research examines exactly what happens when these technologies fail, with the goal of developing a new generation of more robust powered prostheses.

Robotics meet x-ray laser in cutting-edge biology studies

November 24, 2014 8:31 am | by SLAC Office of Communications | News | Comments

Scientists at SLAC National Accelerator Laboratory are combining the speed and precision of robots with one of the brightest x-ray lasers on the planet for pioneering studies of proteins important to biology and drug discovery. The new system uses robotics and other automated components to precisely maneuver delicate samples for study with the x-ray laser pulses at SLAC’s Linac Coherent Light Source.

For important tumor-suppressing protein, context is key

November 24, 2014 8:19 am | by Dan Krotz, Lawrence Berkeley National Laboratory | News | Comments

Scientists from Lawrence Berkeley National Laboratory have learned new details about how an important tumor-suppressing protein, called p53, binds to the human genome. As with many things in life, they found that context makes a big difference. The researchers mapped the places where p53 binds to the genome in a human cancer cell line.

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Model evaluates where bioenergy crops grow best

November 24, 2014 7:59 am | by Liz Ahlberg, Physical Sciences Editor, Univ. of Illinois, Urbana-Champaign | News | Comments

Farmers interested in bioenergy crops now have a resource to help them determine which kind of bioenergy crop would grow best in their regions and what kind of harvest to expect. Researchers at the Univ. of Illinois have published a study identifying yield zones for three major bioenergy crops.

Overcoming limitations of magnetic storage

November 24, 2014 7:49 am | by Emil Venere, Purdue Univ. | News | Comments

Researchers at Nano-Meta Technologies Inc. have shown how to overcome key limitations of a material that could enable the magnetic storage industry to achieve data-recording densities far beyond today's computers. The new technology could make it possible to record data on an unprecedented small scale using tiny "nanoantennas" and to increase the amount of data that can be stored on a standard magnetic disk by 10 to 100 times.

Building on-ramp to cloud computing

November 24, 2014 7:43 am | by Mike Williams, Rice Univ. | News | Comments

Rice Univ. is preparing to offer its researchers who deal in “big data” the opportunity to compute in the cloud with fewer barriers. Rice is installing the Big Research Data Cloud (BiRD Cloud), which will allow for cloud bursting. That means data-intensive tasks can spill over into outside cloud-computing systems when necessary, essentially providing unlimited computing capacity.

Advancements in battery technology shaping the future of electronic vehicles

November 21, 2014 9:57 am | by Canadian Light Source | News | Comments

Scientists at the Canadian Light Source are on the forefront of battery technology using cheaper materials with higher energy and better recharging rates that make them ideal for electric vehicles (EVs). The switch from conventional internal combustion engines to EVs is well underway. However, limited mileage of current EVs due to the confined energy storage capability of available battery systems is why these vehicles aren't more common.

How mutant gene causes deafness

November 21, 2014 9:47 am | by The Scripps Research Institute | News | Comments

Scientists at The Scripps Research Institute (TSRI) have discovered how one gene is essential to hearing, uncovering a cause of deafness and suggesting new avenues for therapies. The new study, published in Neuron, shows how mutations in a gene called Tmie can cause deafness from birth. Underlining the critical nature of their findings, researchers were able to reintroduce the gene in mice and restore the process underpinning hearing.

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Salinity matters when it comes to sea level changes

November 21, 2014 9:33 am | by Anne M. Stark, Lawrence Livermore National Laboraotry | News | Comments

Using ocean observations and a large suite of climate models, Lawrence Livermore National Laboratory (LLNL) scientists have found that long-term salinity changes have a stronger influence on regional sea level changes than previously thought.

What agricultural ecosystems on steroids are doing to the air

November 21, 2014 9:21 am | by Nicole Casal Moore, Univ. of Michigan | News | Comments

In a study that identifies a new, "direct fingerprint" of human activity on Earth, scientists have found that agricultural crops play a big role in seasonal swings of carbon dioxide in the atmosphere. The new findings from Boston Univ., the Univ. of Michigan and other institutions reveal a nuance in the carbon cycle that could help scientists understand and predict how Earth's vegetation will react as the globe warms.

2-D quantum materials for nanoelectronics

November 21, 2014 9:10 am | by David L. Chandler, MIT News Office | News | Comments

Researchers at Massachusetts Institute of Technology say they have carried out a theoretical analysis showing that a family of 2-D materials exhibits exotic quantum properties that may enable a new type of nanoscale electronics. These materials are predicted to show a phenomenon called the quantum spin Hall (QSH) effect, and belong to a class of materials known as transition metal dichalcogenides, with layers a few atoms thick.

Technique allows ultrasound to penetrate bone, metal

November 21, 2014 8:53 am | by Matt Shipman, News Services, North Carolina State Univ. | News | Comments

Researchers from North Carolina State Univ. have developed a technique that allows ultrasound to penetrate bone or metal, using customized structures that offset the distortion usually caused by these so-called “aberrating layers.” The researchers addressed this problem by designing customized metamaterial structures that take into account the acoustic properties of the aberrating layer and offsetting them.

Quantum mechanical calculations reveal the hidden states of enzyme active sites

November 21, 2014 8:37 am | by Princeton Univ. | News | Comments

Enzymes carry out fundamental biological processes such as photosynthesis, nitrogen fixation and respiration, with the help of clusters of metal atoms as "active" sites. But scientists lack basic information about their function because the states thought to be critical to their chemical abilities cannot be experimentally observed.

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Collaboration points to improved nanomaterials

November 21, 2014 8:01 am | by Jim Barlow, Director of Science and Research Communications, Univ. of Oregon | News | Comments

A potential path to identify imperfections and improve the quality of nanomaterials for use in next-generation solar cells has emerged from a collaboration of Univ. of Oregon and industry researchers. To increase light-harvesting efficiency of solar cells beyond silicon's limit of about 29%, manufacturers have used layers of chemically synthesized semiconductor nanocrystals.

Deep-Earth carbon offers clues about origin of life

November 21, 2014 7:53 am | by Jill Rosen, Johns Hopkins Univ. | News | Comments

New findings by a Johns Hopkins Univ.-led team reveal long unknown details about carbon deep beneath the Earth’s surface and suggest ways this subterranean carbon might have influenced the history of life on the planet. The team also developed a new, related theory about how diamonds form in the Earth’s mantle.

Researchers create first inhibitor for enzyme linked to certain cancers

November 21, 2014 7:49 am | by Univ. of California, Irvine | News | Comments

Recent studies showing acid ceramidase (AC) to be upregulated in melanoma, lung and prostate cancers have made the enzyme a desired target for novel synthetic inhibitor compounds. In Angewandte Chemie, scientists with the Univ. of California, Irvine School of Medicine and the Italian Institute of Technology describe the very first class of AC inhibitors that may aid in the efficacy of chemotherapies.

Discovery sheds light on nuclear reactor fuel behavior during a severe event

November 21, 2014 7:43 am | by Anglea Hardin, Argonne National Laboratory | News | Comments

A new discovery about the atomic structure of uranium dioxide will help scientists select the best computational model to simulate severe nuclear reactor accidents. Using the Advanced Photon Source, a team of researchers found that the atomic structure of uranium dioxide (UO2) changes significantly when it melts.

U.S. approves new, hard-to-abuse hydrocodone pill

November 20, 2014 6:00 pm | by Matthew Perrone - AP Health Writer - Associated Press | News | Comments

U.S. government health regulators on Thursday approved the first hard-to-abuse version of the painkiller hydrocodone, offering an alternative to a similar medication that has been widely criticized for lacking such safeguards. The FDA approved Purdue Pharma's Hysingla ER for patients with severe, round-the-clock pain that cannot be managed with other treatments.

Center Stage: The High Rollers of S&T Industry Honored at 2014 R&D 100 Awards

November 20, 2014 12:06 pm | by Lindsay Hock, Managing Editor | Award Winners

The R&D 100 Awards have a 50+ year history of recognizing excellence in innovation, earning the name the “Oscars of Invention." And at the annual event, the high rollers of the science and technology industry were honored on stage for their innovative, high-tech products and processes that are, or will, make a difference in our everyday lives.

Novel polarizing filter transits more light

November 20, 2014 9:29 am | by Univ. of Utah | News | Comments

Univ. of Utah engineers have developed a polarizing filter that allows in more light, leading the way for mobile device displays that last much longer on a single battery charge and cameras that can shoot in dim light. Polarizers are indispensable in digital photography and LCD displays, but they block enormous amounts of light, wasting energy and making it more difficult to photograph in low light.

New technology may speed up, build awareness of landslide risks

November 20, 2014 9:18 am | by David Stauth, Oregon State Univ. | News | Comments

Engineers have created a new way to use lidar technology to identify and classify landslides on a landscape scale, which may revolutionize the understanding of landslides in the U.S. and reveal them to be far more common and hazardous than often understood. The new, non-subjective technology can analyze and classify the landslide risk in an area of 50 or more square miles in about 30 mins.

Paper electronics could make health care more accessible

November 20, 2014 9:02 am | by American Chemical Society | News | Comments

Flexible electronic sensors based on paper have the potential to cut the price of a wide range of medical tools, from helpful robots to diagnostic tests. Scientists have now developed a fast, low-cost way of making these sensors by directly printing conductive ink on paper.

Unique sense of “touch” gives a prolific bacterium its ability to infect anything

November 20, 2014 8:49 am | by Morgan Kelly, Office of Communications, Princeton Univ. | Videos | Comments

New research has found that one of the world's most prolific bacteria manages to afflict humans, animals and even plants by way of a mechanism not before seen in any infectious microorganism—a sense of touch. This unique ability helps make the bacteria Pseudomonas aeruginosa ubiquitous, but it also might leave these antibiotic-resistant organisms vulnerable to a new form of treatment.

Spiraling light, nanoparticles and insights into life’s structure

November 20, 2014 8:12 am | by Nicole Casal Moore, Univ. of Michigan | News | Comments

As hands come in left and right versions that are mirror images of each other, so do the amino acids and sugars within us. But unlike hands, only the left-oriented amino acids and the right-oriented sugars ever make into life as we know it. Scientists know the other varieties exist because when they synthesize these amino acids and sugars in a laboratory, roughly equal numbers of left- and right-facing arrangements form.

“Cloaking” device uses ordinary lenses to hide objects across range of angles

November 20, 2014 7:51 am | by Univ. of Rochester | News | Comments

Inspired perhaps by Harry Potter's invisibility cloak, scientists have recently developed several ways to hide objects from view. The latest effort, developed at the Univ. of Rochester, not only overcomes some of the limitations of previous devices, but it uses inexpensive, readily available materials in a novel configuration.

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