A faster and less expensive form of radiotherapy for treating prostate cancer may come at a price, according to a new study by Yale School of Medicine researchers—a higher rate of urinary toxicity or urine poisoning. The standard therapy for prostate cancer is called intensity modulated radiation therapy (IMRT). Stereotactic body radiotherapy (SBRT) is a newer treatment that delivers a greater dose of radiation than IMRT.
Changing the texture and surface characteristics of a semiconductor material at the nanoscale...
Sometimes it only takes a quick jolt of electricity to get a swarm of cells moving in the right...
Researchers at North Carolina State Univ. have developed the equivalent of GPS directions for...
These days, it's faster and cheaper than ever to decipher a person's entire DNA. But a small U.S. study suggests that looking for disease risks that way may not be ready for the masses. For one thing, the research found that gene variants most likely linked with significant disease were the least likely to be accurately identified.
The U.S. Food and Drug Administration said Tuesday it approved a Belgium-made nerve-stimulating headband as the first medical device to prevent migraine headaches. Agency officials said the device provides a new option for patients who can't tolerate migraine medications. The Cefaly device is a battery-powered plastic band worn across the forehead.
Biomedical engineering researchers have developed a new technique that uses adenosine-5’-triphosphate (ATP), the so-called “energy molecule,” to trigger the release of anti-cancer drugs directly into cancer cells. Early laboratory tests show it increases the effectiveness of drugs targeting breast cancer. The technique was developed by researchers at North Carolina State Univ. and the Univ. of North Carolina at Chapel Hill.
The Riken Center for Development Biology in Kobe, Japan, has been looking into questions raised over images and wording in a research paper describing a simple way of turning ordinary cells from mice into stem cells. Riken said Tuesday that it may retract the paper because of credibility and ethics issues, even though an investigation is continuing.
Smartphones are capable of giving us directions when we’re lost, sending photos and videos to our friends in mere seconds and, perhaps very soon, diagnose our diseases in real time. Researchers in Texas are developing a disease diagnostic system made of a glass slide and a porous film of gold that offers results that could be read using only a smartphone and a $20 lens attachment.
Fresh banana, a waft of flowers, blueberry: the scents in Shota Atsumi's laboratory in the Univ. of California, Davis Dept. of Chemistry are a little sweeter than most. That's because Atsumi and his team are engineering bacteria to make esters, molecules widely used as scents and flavorings, and also as basic feedstock for chemical processes from paints to fuels.
About 90% of cancer deaths are caused by tumors that have spread from their original locations. This process, known as metastasis, requires cancer cells to break loose from their neighbors and from the supportive scaffold that gives tissues their structure. Cancer biologists have now discovered that certain proteins in this structure, known as the extracellular matrix, help cancer cells make their escape.
It's not just grandma with a new hip and your uncle with a new knee. More than two of every 100 Americans now have an artificial joint, doctors are reporting. Among those over 50, it's even more common: 5% have replaced a knee and more than 2%, a hip.
Over the past 20 years, the number of laboratory tests available to primary care physicians has doubled, to more than 3,500 tests, and physicians are challenged by the quantity of tests available. A recent survey conducted by the U.S. Centers for Disease Control and Prevention suggests they often face uncertainty in ordering and interpreting clinical laboratory tests, and would welcome better electronic clinical decision support tools.
Ever since the study of individual genes and RNAs was first known to be important, there has been a drive to get as detailed and complete genomic information as possible. Early technologies like the hybridization-based Southern and Northern blotting methods were tremendous advances, but allowed only a handful of genomic targets to be studied at a time.
A new type of biomolecular tweezers could help researchers study how mechanical forces affect the biochemical activity of cells and proteins. The devices use opposing magnetic and electrophoretic forces to precisely stretch the cells and molecules, holding them in position so that the activity of receptors and other biochemical activity can be studied.
In a significant advance for the growing field of synthetic biology, Rice Univ. bioengineers have created a toolkit of genes and hardware that uses colored lights and engineered bacteria to bring both mathematical predictability and cut-and-paste simplicity to the world of genetic circuit design.
In end-stage lung disease, transplantation is sometimes the only viable therapeutic option, but organ availability is limited and rejection presents an additional challenge. New methods and techniques in the field of tissue regeneration hold promise for this population, which includes an estimated 12.7 million people with chronic obstructive pulmonary disorder (COPD).
A team of Univ. of Notre Dame researchers have discovered a new class of antibiotics to fight bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and other drug-resistant bacteria. Called oxadiazoles, the new class was discovered through in silico (by computer) screening and has shown promise in the treatment of MRSA in mouse models of infection.
In a new study that could help doctors extend the lives of patients awaiting liver transplants, a Rice Univ.-led team of researchers examined the metabolic breakdown that takes place in liver cells during late-stage cirrhosis and found clues that suggest new treatments to delay liver failure.
Researchers at the Stanford Univ. School of Medicine have developed two inexpensive adapters that enable a smartphone to capture high-quality images of the front and back of the eye. The adapters make it easy for anyone with minimal training to take a picture of the eye and share it securely with other health practitioners or store it in the patient’s electronic record.
When a person becomes sick or is exposed to an unwelcome substance, the body mobilizes specific proportions of different immune cells in the blood. Methods of discovering and detecting those profiles are therefore useful both clinically and in research. In a new Genome Biology paper, a team of scientists describes a new and uniquely advantageous way to detect them.
Paleontologists studying fossilized feathers have proposed that the shapes of certain microscopic structures inside the feathers can tell us the color of ancient birds. But new research from North Carolina State Univ. demonstrates that it is not yet possible to tell if these structures, thought to be melanosomes, are what they seem, or if they are merely the remnants of ancient bacteria.
Samples are precious resources and integral to the research process. The information derived from them is dependent on their quality, integrity and consistency. And, many samples represent a scientist’s investment in and trust of the biomedical research process. Yet, it is not unusual for samples to go missing, to find that their labels have fallen off or that they have become unusable.
Researchers from North Carolina State Univ. have developed a computational tool designed to guide future research on biochemical pathways by identifying which components in a biological system are related to specific biochemical processes, including those processes responsible for gene expression, cell signaling, stress response and metabolism.
Scientists who study past pandemics, such as the 14th-century Black Death that devastated much of Europe, might soon be turning to an innovative biological detection technology for some extra help. The apparent first use of this technology, known as a microarray, for studying pathogens from ancient DNA, was reported by a team of scientists in Scientific Reports.
A bit of pressure from a new shrinking, sponge-like gel is all it takes to turn transplanted unspecialized cells into cells that lay down minerals and begin to form teeth. The bioinspired gel material could one day help repair or replace damaged organs, such as teeth and bone, and possibly other organs as well.
Protein from a small, tasty mollusk inspired Michigan Technological Univ.’s Bruce P. Lee to invent a new type of hydrogel actuator. Hydrogels are soft networks of polymers with high water content, like jello. Because of their soft, gentle texture, they have the potential to interact safely with living tissues and have applications in a number of medical areas, including tissue engineering.
Imagine driving on a dark road. In the distance you see a single light. As the light approaches it splits into two headlights. That’s a car, not a motorcycle, your brain tells you. A new study found that neural circuits in the brain rapidly multitask between detecting and discriminating sensory input, such as headlights in the distance.
Rice Univ. researchers have developed a theoretical approach to analyze the process by which protein building blocks form the biopolymer skeletons of living cells. The cytoskeleton, made of fibers and microtubules, gives a cell its shape and provides the “roads” along which proteins and other cargoes travel.
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