Performing systematic analyses of both known and imagined chemical compounds to find their key properties, Northwestern Univ. engineers have created a database that takes some of the guesswork out of designing new materials. Called the Open Quantum Materials Database (OQMD), it launched in November and is the largest database in the world of its kind, containing analyses of 285,780 compounds and growing.
Some of the most damaging brain diseases can be traced to irregular blood delivery in the brain. Now, Stanford Univ. chemists have employed lasers and carbon nanotubes to capture an unprecedented look at blood flowing through a living brain. The technique was developed for mice but could one day be applied to humans, potentially providing vital information in the study of stroke and migraines.
These days, unmanned aerial vehicles (UAV) typically fly alone with a team of ground operators controlling their activities through teleoperation or waypoint-based routing. But one aircraft can only carry so many sensors, limiting its capabilities. That’s one reason why a fleet of autonomous aircraft can be better than one flying alone.
A Purdue Univ. study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment. The research team found that blocking Notch signaling in the fat tissue of mice caused white fat cells to transform into a "leaner" type of fat known as beige fat.
Recent research has made a significant contribution to the understanding of a new field of DNA research that is based on a repetitive piece of DNA in the bacterial genome called a CRISPR. The study provides the first detailed blueprint for this multi-subunit “molecular machinery” that bacteria use to detect and destroy invading viruses.
A fundamental chemical pathway that all plants use to create an essential amino acid needed by all animals to make proteins has now been traced to two groups of ancient bacteria. The pathway is also known for making hundreds of chemicals, including a compound that makes wood strong and the pigments that make red wine red.
The current Ebola crisis in West Africa is on pace to sicken more people than all other previous outbreaks of the disease combined, a U.S. health official said Thursday. Dr. Tom Frieden, director of the Centers for Disease Control and Prevention, told a congressional hearing that the outbreak is unprecedented in part because it's in a region of Africa that never has dealt with Ebola before.
Borrowing from the ancient Japanese art of origami, children's toys and even a touch of the "Transformers" movies, scientists and engineers at Harvard University and the Massachusetts Institute of Technology have created self-assembling, paper robots. These complex machines transform themselves from little more than a sheet of paper and plastic into walking automatons.
Turning what seemed like a science fiction tale into reality, an unmanned probe swung alongside a comet on Wednesday after a 4-billion mile chase through outer space over the course of a decade. Europe's Rosetta probe will orbit and study the giant lump of dust and ice as it hurtles toward the sun and, if all goes according to plan, drop a lander onto the comet in the coming months.
For decades, scientists have been trying to use quantum systems for logical calculations, but implementing a system that manages superposition states is challenging. A team of researchers in Austria and Japan has now proposed a new architecture based on microscopic defects in diamond. They are convinced that the basic elements of their newly proposed architecture are better suited to be miniaturized, mass-produced and integrated on a chip.
A bug can turn you into a vegetarian, or at least make you swear off red meat. Doctors across the nation are seeing a surge of sudden meat allergies in people bitten by a certain kind of tick. This bizarre problem was only discovered a few years ago but is growing as the ticks spread from the Southwest and the East to more parts of the United States.
Physicists at NIST have demonstrated a pas de deux of atomic ions that combines the fine choreography of dance with precise individual control. NIST’s ion duet is a component for a flexible quantum simulator that could be scaled up in size and configured to model quantum systems of a complexity that overwhelms traditional computer simulations.
Melanoma is the fifth most common cancer type in the United States. A new handheld device may help diagnosis and treatment efforts for the disease. It uses lasers and sound waves and is the first that can be used directly on a patient to accurately measure how deep a melanoma tumor extends into the skin.
For the first time, researchers have succeeded in "growing" single-wall carbon nanotubes (CNT) with a single predefined structure, and hence with identical electronic properties. The method involved self-assembly of tailor-made organic precursor molecules on a platinum surface. In the future, carbon nanotubes of this kind may be used in ultra-sensitive light detectors and ultra-small transistors.
Brain tumors fly under the radar of the body’s defense forces by coating their cells with extra amounts of a specific protein, new research at the Univ. of Michigan shows. The findings, made in mice and rats, show the key role of a protein called galectin-1 in some of the most dangerous brain tumors, called high grade malignant gliomas. The stealth approach lets the tumors hide until it’s too late for the body to defeat them.
Researchers at Yale School of Medicine have discovered a new drug compound that reverses the brain deficits of Alzheimer’s disease in an animal model. The compound, TC-2153, inhibits the negative effects of a protein called STtriatal-Enriched tyrosine Phosphatase (STEP), which is key to regulating learning and memory. These cognitive functions are impaired in Alzheimer’s.
Researchers at SLAC National Accelerator Laboratory have developed a laser-timing system that could allow scientists to take snapshots of electrons zipping around atoms and molecules. Taking timing to this new extreme of speed and accuracy at the Linac Coherent Light Source x-ray laser will make it possible to see the formative stages of chemical reactions.
Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that carry the genetic flaw—but breeding such mice is an expensive, time-consuming process. Now, Massachusetts Institute of Technology researchers have found an alternative.
It's long been known that faulty BRCA genes greatly raise the risk for breast cancer. Now scientists say a more recently identified, less common gene can do the same. Mutations in the gene can make breast cancer up to nine times more likely to develop, an international team of researchers reports in the New England Journal of Medicine.
MIT engineers have fabricated a new elastic material coated with microscopic, hairlike structures that tilt in response to a magnetic field. Depending on the field’s orientation, the microhairs can tilt to form a path through which fluid can flow; the material can even direct water upward, against gravity. Researchers say structures may be used in windows to wick away moisture.
In 2012, a team of researchers in London imaged, for the first time, the structure of the DNA double helix. James Watson and Francis Crick discovered DNA 60 years ago by laboriously studying x-ray diffraction images of millions of DNA molecules. However, Dr. Bart Hoogenboom and Dr. Carl Leung used atomic force microscopy (AFM) to directly “feel” the molecule’s structure in a fraction of the time.
Traditional lithography is based on a simple principle: Oil and water don’t mix. The method, first developed by an actor in Bavaria in 1796, used a smooth piece of limestone on which an oil-based image was drawn and overlayed with gum arabic in water. During printing, the ink was attracted to the oil, and was repelled by the gum.
Life science researchers are benefiting from easy-to-use, ultra-fast, automated and integrated platforms that address specific application needs. These platforms combine hardware, software and reagents into integrated, push-button analysis systems capable of transforming workflows which once took several days into minutes.
To help them further the study of cell function, a team of Stanford Univ. bioengineers has designed a suite of protein motors that can be controlled remotely by light. Splicing together DNA from different organisms such as pig, slime mold and oat, which has a light-detecting module, the team created DNA codes for each of their protein motors. When exposed to light, the new protein motors change direction or speed.
In the ultra-low-temperature (ULT) freezer market there’s a continued focus on sample protection. As users store priceless samples, they need to have ULT freezers that provide them with quick recovery and uniformity after door openings. However, for most users, the trend is pointing to energy efficiency and cost, as ULT freezers cost as much to operate in a year as an average American household, according to the Univ. of California, Davis.