Biomedical engineering researchers have developed a new technique that uses adenosine-5’-triphosphate (ATP), the so-called “energy molecule,” to trigger the release of anti-cancer drugs directly into cancer cells. Early laboratory tests show it increases the effectiveness of drugs targeting breast cancer. The technique was developed by researchers at North Carolina State Univ. and the Univ. of North Carolina at Chapel Hill.
The Riken Center for Development Biology in Kobe,...
Photovoltaic spray paint could coat the windows...
A new system at SLAC National Accelerator Laboratory's x-ray laser narrows a rainbow spectrum of x-ray colors to a more intense band of light, creating a much more powerful way to view fine details in samples at the scale of atoms and molecules. Designed and installed at SLAC's Linac Coherent Light Source, it's the world’s first self-seeding system for enhancing lower-energy or soft x-rays.
Imagine that you are in a meeting with coworkers or at a gathering of friends. You pull out your cell phone to show a presentation or a video on YouTube. But you don't use the tiny screen; your phone projects a bright, clear image onto a wall or a big screen. Such a technology may be on its way, thanks to a new light-bending silicon chip developed by researchers at the California Institute of Technology.
About 90% of cancer deaths are caused by tumors that have spread from their original locations. This process, known as metastasis, requires cancer cells to break loose from their neighbors and from the supportive scaffold that gives tissues their structure. Cancer biologists have now discovered that certain proteins in this structure, known as the extracellular matrix, help cancer cells make their escape.
Laboratory Design Newsletter features new laboratory construction, renovation and adaptive reuse projects in each issue and also online. The new projects section of the Website hosts a large variety of laboratory builds in academic, medical, private, commercial and government laboratories.
Most modern electronics, from flatscreen TVs and smartphones to wearable technologies and computer monitors, use tiny light-emitting diodes, or LEDs. These LEDs are based off of semiconductors that emit light with the movement of electrons. As devices get smaller and faster, there is more demand for such semiconductors that are tinier, stronger and more energy efficient.
Graphene is not the only ultrathin material that exhibits special electronic properties. Ultrathin layers made of tungsten and selenium have recently been created in Austria that show a high internal efficiency when used to gather sunlight. More than 95% of light passes straight through, but a tenth of what is stopped is converted to electricity.
Despite their potential to reduce carbon dioxide emissions and fuel consumption, electric and hybrid cars and trucks struggled for years to find a solid customer base. Much of the reason came down to cost and convenience: Electric car batteries are expensive, and charging them requires plug-in infrastructure that’s still sparse in the U.S.
The nature of science shares striking similarities across many industry verticals. Whether it’s biologics, chemicals or new product formulations, they are all performed with a high degree of similarity from company to company. This is exemplified by the fact that R&D informatics platforms such as LIMS, ELNs and SDMS are used, and provide real benefits in all science-related sectors.
Ever since the study of individual genes and RNAs was first known to be important, there has been a drive to get as detailed and complete genomic information as possible. Early technologies like the hybridization-based Southern and Northern blotting methods were tremendous advances, but allowed only a handful of genomic targets to be studied at a time.
A new type of biomolecular tweezers could help researchers study how mechanical forces affect the biochemical activity of cells and proteins. The devices use opposing magnetic and electrophoretic forces to precisely stretch the cells and molecules, holding them in position so that the activity of receptors and other biochemical activity can be studied.
In a significant advance for the growing field of synthetic biology, Rice Univ. bioengineers have created a toolkit of genes and hardware that uses colored lights and engineered bacteria to bring both mathematical predictability and cut-and-paste simplicity to the world of genetic circuit design.
A team of Massachusetts Institute of Technology researchers has used a novel material that’s just a few atoms thick to create devices that can harness or emit light. This proof-of-concept could lead to ultra-thin, lightweight and flexible photovoltaic cells, light-emitting diodes (LEDs) and other optoelectronic devices, they say.
Although NASA’s Human Research Program has been researching the effects of spaceflight on the human body for decades, the March 7 announcement of 10 investigations for the study of identical twin astronauts Scott and Mark Kelly will provide a broader insight into the subtle effects and changes that may occur in spaceflight as compared to Earth-based environments.
In end-stage lung disease, transplantation is sometimes the only viable therapeutic option, but organ availability is limited and rejection presents an additional challenge. New methods and techniques in the field of tissue regeneration hold promise for this population, which includes an estimated 12.7 million people with chronic obstructive pulmonary disorder (COPD).
A team of Univ. of Notre Dame researchers have discovered a new class of antibiotics to fight bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and other drug-resistant bacteria. Called oxadiazoles, the new class was discovered through in silico (by computer) screening and has shown promise in the treatment of MRSA in mouse models of infection.
Researchers have theorized about the existence of this large, but unseen celestial body, suspected to lie somewhere beyond the orbit of Pluto. After searching hundreds of millions of objects across our sky, NASA's Wide-Field Infrared Survey Explorer (WISE) has turned up no evidence of the commonly dubbed "Planet X."
Future lunar missions may be fueled by gas stations in space, according to Massachusetts Institute of Technology engineers: A spacecraft might dock at a propellant depot, somewhere between the Earth and the moon, and pick up extra rocket fuel before making its way to the lunar surface.
Researchers at the Stanford Univ. School of Medicine have developed two inexpensive adapters that enable a smartphone to capture high-quality images of the front and back of the eye. The adapters make it easy for anyone with minimal training to take a picture of the eye and share it securely with other health practitioners or store it in the patient’s electronic record.
Experts from the Univ. of Buffalo (UB), helped by colleagues from two Chinese universities, have developed an optical "nanocavity" that could help increase the amount of light absorbed by ultrathin semiconductors. The advancement could lead to the creation of more powerful photovoltaic cells and improvements in video cameras and even hydrogen fuel, as the technology could aid the splitting of water using energy from light.
A new mechanism of controlling magnetic states by electric currents has been discovered by an international team of researchers who have exploited a quantum phenomenon to control magnetic states with electrical currents. The research hinges on a quantum geometrical phase, called the Berry phase, that exists in the momentum space of electronic band structures in specific materials.
Researchers at Harvard Univ.'s Wyss Institute have developed a method to carry out large-scale manufacturing of everyday objects using a fully degradable bioplastic isolated from shrimp shells. The objects exhibit many of the same properties as those created with synthetic plastics, but without the environmental threat. It also trumps most bioplastics on the market today in posing absolutely no threat to trees.
Paleontologists studying fossilized feathers have proposed that the shapes of certain microscopic structures inside the feathers can tell us the color of ancient birds. But new research from North Carolina State Univ. demonstrates that it is not yet possible to tell if these structures, thought to be melanosomes, are what they seem, or if they are merely the remnants of ancient bacteria.
An experiment at SLAC National Accelerator Laboratory’s x-ray laser has revealed the first atomic-scale details of a new technique that could point the way to faster data storage in smartphones, laptops and other devices. Researchers used pulses of specially tuned light to change the magnetic properties of a material with potential for data storage.
Light can trigger coordinated, wave-like motions of atoms in atom-thin layers of crystal, scientists have shown. The waves, called phonon polaritons, are far shorter than light waves and can be "tuned" to particular frequencies and amplitudes by varying the number of layers of crystal, they report.
Flawed but colorful diamonds are among the most sensitive detectors of magnetic fields known today, allowing physicists to explore the minuscule magnetic fields in metals, exotic materials and even human tissue. A team of physicists have now shown that these diamond sensors can measure the tiny magnetic fields in high-temperature superconductors, providing a new tool to probe these much ballyhooed but poorly understood materials.
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