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Potent, puzzling and (now less) toxic: Team discovers how antifungal drug works

April 15, 2014 5:18 pm | by Diana Yates, Univ. of Illinois | News | Comments

Scientists have solved a decades-old medical mystery, and in the process have found a potentially less toxic way to fight invasive fungal infections, which kill about 1.5 million people a year. The researchers say they now understand the mechanism of action of amphotericin, an antifungal drug that has been in use for more than 50 years even though it is nearly as toxic to human cells as it is to the microbes it attacks.

Computational record: Earthquake simulation tops one quadrillion flops

April 15, 2014 4:28 pm | News | Comments

A team of computer scientists, mathematicians and...

Relieving electric vehicle range anxiety with improved batteries

April 15, 2014 3:29 pm | News | Comments

The chemistry of lithium-ion batteries limits how...

Astronomers: ‘Tilt-a-worlds’ could harbor life

April 15, 2014 3:17 pm | by Peter Kelley, Univ. of Washington | News | Comments

A fluctuating tilt in a planet’s orbit does not...

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Sensitive detection method may help impede illicit nuclear trafficking

April 15, 2014 12:34 pm | News | Comments

According to a new study, coupling commercially available spectral x-ray detectors with a specialized algorithm can improve the detection of uranium and plutonium in small, layered objects such as baggage. This approach enhances the detection powers of x-ray imaging and may provide a new tool to impede nuclear trafficking.

Google buys drone maker Titan Aerospace

April 15, 2014 12:26 pm | by Barbara Ortutay, AP Technology Writer | News | Comments

Titan Aerospace, a maker of solar-powered drones, has been purchased by Google, which says it could help bring Internet access to remote parts of the world. Titan's atmospheric satellites, which are still in development and not yet commercially available, can stay in the air for as long as five years. Titan's website has cited a wide range of uses for the drones.

Nanocrystalline cellulose modified into an efficient viral inhibitor

April 15, 2014 11:38 am | News | Comments

Researchers in Finland have succeeded in creating a surface on nano-sized cellulose crystals that imitates a biological structure. The surface adsorbs viruses and disables them, preventing their spread into cells. The results could prove useful in the development of antiviral ointments and surfaces.

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Moth study suggests hidden climate change impacts

April 15, 2014 11:23 am | by Jim Erickson, Univ. of Michigan | News | Comments

A 32-year study of subarctic forest moths in Finnish Lapland suggests that scientists may be underestimating the impacts of climate change on animals and plants because much of the harm is hidden from view. The study analyzed populations of 80 moth species and found that 90% of them were either stable or increasing throughout the study period, from 1978 to 2009.

An Arctic ozone hole? Not quite

April 15, 2014 11:06 am | by Audrey Resutek, MIT | News | Comments

Since the discovery of the Antarctic ozone hole, scientists, policymakers and the public have wondered whether we might someday see a similarly extreme depletion of ozone over the Arctic. But a new Massachusetts Institute of Technology study finds some cause for optimism: Ozone levels in the Arctic haven’t yet sunk to the extreme lows seen in Antarctica, because international efforts to limit ozone-depleting chemicals have been successful.

Lab Utilities Make the Grade

April 15, 2014 10:08 am | by Paul Livingstone | Erlab, Inc., Pfeiffer Vacuum, Oerlikon Leybold Vacuum USA | Articles | Comments

All types of research laboratories rely on a set of core utilities to enable and support work functions. These are often overlooked as a commodity called “consumables”, but in reality they are indispensable nutrients that vary greatly in quality and reliability. Just as a human can’t exist without water, oxygen and food, the research facility cannot make do without water, gas, air, lighting and, increasingly, high-throughput data.

A Spectral Overview

April 15, 2014 9:56 am | by Lindsay Hock, Managing Editor | Thermo Fisher Scientific, Ocean Optics, Shimadzu Scientific Instruments | Articles | Comments

Spectroscopy is an analytical technique used to identify and determine the physical characteristics of materials through the measurement of emissions and absorption of electromagnetic spectra. A staple in any research laboratory, the technique makes its main home in pharmaceutical, biotechnology and chemical laboratories.

When Physical Prototypes Fail, Simulation Provides the Answers

April 15, 2014 9:45 am | by Alexandra Foley, COMSOL Inc. | COMSOL, Inc. | Articles | Comments

In today’s fast-paced markets, engineers are continuously challenged to deliver products that meet market demand, improve operational efficiency and exceed customer expectations. Multiphysics simulation is an essential component of the product design workflow for creating innovative designs, especially when building prototypes becomes impractical or when taking actual measurements is not possible.

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Engineers develop new materials for hydrogen storage

April 15, 2014 9:43 am | News | Comments

Researchers in California have created, for the first time, compounds made from mixtures of calcium hexaboride, strontium and barium hexaboride. They also demonstrated that these ceramic materials could be manufactured using a simple, low-cost manufacturing method known as combustion synthesis.

Characterizing Liposomes for Drug Delivery

April 15, 2014 9:38 am | by Pauline Carnell, Senior Application Scientist and Mike Kaszuba, Technical Support Manager, Malvern Instruments, Malvern, U.K | Articles | Comments

When considering potential drug delivery vehicles, liposomes are an important option and have already been approved for use with a number of therapeutic formulations. Liposomes are comprised of phospholipids and may be single- or multi-layered, can be produced in different sizes and have a hydrophilic interior and hydrophobic shell. They are biodegradable, non-toxic and capable of encapsulating both hydrophilic and hydrophobic materials.

Jefferson Lab accelerator achieves 12 GeV commissioning milestone

April 15, 2014 9:31 am | News | Comments

Following an upgrade of the Continuous Electron Beam Accelerator Facility at the Thomas Jefferson National Accelerator Facility, the accelerator delivered the highest-energy electron beams it has ever produced into a target, recording the first data of the 12 GeV era. The machine sent electrons around the racetrack three times, resulting in 6.11 GeV electrons at 2 nanoAmps average current for more than an hour.

Nano shake-up: Nanocarriers fluctuate in size and shape

April 15, 2014 9:26 am | by Diane Kukich, Univ. of Delaware | News | Comments

Nanotechnology has unlocked new pathways for targeted drug delivery, including the use of nanocarriers that can transport cargoes of small-molecule therapeutics to specific locations in the body. Researchers have recently demonstrated that processing can have significant influence on the size of nanocarriers for targeted drug delivery. It was previously assumed that once a nanocarrier is created, it maintains its size and shape anywhere.

3-D Printing: A New Manufacturing Staple

April 15, 2014 9:24 am | by Lindsay Hock, Managing Editor | Stratasys, Ltd. | Articles | Comments

Thirty years have passed since 3-D printers first appeared, but only recently have they hinted at a new era of manufacturing. The first working 3-D printer was created in 1984 by Chuck Hull of 3D Systems Corp. This early device, based on stereolithography, gave way to the first truly practical 3-D printing, or “3DP”, technology patented by the Massachusetts Institute of Technology in 1993.

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A New Clarity

April 15, 2014 9:16 am | by Paul Livingstone | Ocean Optics, PI (Physik Instrumente) LP, HORIBA Scientific | Articles | Comments

Few areas of instrumentation have prompted as much development or efforts toward innovation as spectroscopy. Without sophisticated approaches to handling light, spectrometers as we know them would not function, and we would be without a deep understanding of the chemical nature of the world around us.

Life Sciences Chrome

April 15, 2014 9:04 am | by Lindsay Hock, Managing Editor | Thermo Fisher Scientific, Agilent Technologies Inc. | Articles | Comments

Driven by rapid growth in forensics, biotechnology, disease diagnostics and environmental regulations, chromatography systems have become a laboratory staple. Used for the separation of complex mixtures, detection of illicit drugs and the production of pharmaceuticals, the biotechnology and pharmaceutical industries are the prime users of chromatography techniques.

The Benefits of Single-particle ICP MS for the Characterization of Engineered Nanomaterials

April 15, 2014 8:41 am | by Rob Thomas | Articles | Comments

The unique properties of engineered nanoparticles have created intense interest in their environmental behavior. Due to the increased use of nanotechnology in consumer products, industrial applications and health care technology, nanoparticles are more likely to enter the environment. For this reason, it’s not only important to know the type, size and distribution of nanoparticles, but it’s also crucial to understand their impact.

Oil and Gas Industry Training Requires Rich New Technology

April 15, 2014 8:06 am | by Oliver Diaz, CEO and Founder, FuelFX | Articles | Comments

The stakes are incredibly high for the safety and compliance efforts of today’s oil and gas industry. Engineers and crews must be trained for increasingly complex processes and procedures used aboard drilling rigs and production platforms. The consequences of inadequate training during oil production can be disastrous to both operator crews and the environment.

Pass the Mustard; Why Carinata is Taking Root as Biofuel

April 15, 2014 7:56 am | by Don Konantz, President/CEO, Calyx Bio-Ventures, Vancouver, British Columbia | Articles | Comments

Navigant Research forecasts that the “global biofuels production will reach 61 billion gallons by 2023, replacing nearly 6% of global transportation fuel production from fossil sources and generating $70 billion in new revenue over the next decade.” The demand for an appropriate crop that can provide biofuels, without competing for land use with food crops, is on.

A few “problem wells” source of greenhouse gas

April 15, 2014 7:48 am | by Elizabeth K. Gardner, Purdue Univ. | News | Comments

High levels of the greenhouse gas methane were found above shale gas wells at a production point not thought to be an important emissions source, according to a study jointly led by Purdue and Cornell universities. The findings could have implications for the evaluation of the environmental impacts from natural gas production.

Targeting cancer with a triple threat

April 15, 2014 7:38 am | by Anne Trafton, MIT News Office | News | Comments

Delivering chemotherapy drugs in nanoparticle form could help reduce side effects by targeting the drugs directly to the tumors. In recent years, scientists have developed nanoparticles that deliver one or two chemotherapy drugs, but it has been difficult to design particles that can carry any more than that in a precise ratio. Now Massachusetts Institute of Technology chemists have devised a new way to build such nanoparticles.

Rocket leak delays space station delivery launch

April 14, 2014 4:21 pm | by Marcia Dunn - AP Aerospace Writer - Associated Press | News | Comments

A space station cargo ship will remain Earthbound for a while longer. With just over an hour remaining, the Space X company called off Monday's planned launch because of a rocket leak. A new launch date was not set; the next opportunity would be Friday. Officials said a helium leak in the first-stage of the unmanned Falcon rocket forced the postponement. The launch already had been delayed a full month for various reasons.

Scientists open door to better solar cells, superconductors and hard-drives

April 14, 2014 1:05 pm | News | Comments

Recent research using free-electron laser sources has enhanced the understanding of the interface of two materials, where completely new properties can arise. For instance, two insulators and non-magnetic materials can become metallic and magnetic at their interface. The breakthrough was the discovery of a discrepancy in the number of charge carriers of two promising electronic materials.

Research finds “tunable” semiconductors will allow better detectors, solar cells

April 14, 2014 12:53 pm | by Ann Claycombe, Georgia State Univ. | News | Comments

One of the great problems in physics is the detection of electromagnetic radiation—that is, light—which lies outside the small range of wavelengths that the human eye can see. Think x-rays, for example, or radio waves. Now, researchers have discovered a way to use existing semiconductors to detect a far wider range of light than is now possible, well into the infrared range.

Combs of light accelerate communication

April 14, 2014 11:39 am | News | Comments

In a recent demonstration by researchers in Europe, miniaturized optical frequency comb sources allow for transmission of data streams of several terabits per second over hundreds of kilometers. The results, which showed a data rate of 1.44 TB/sec over 300 km, may contribute to accelerating data transmission in large computing centers and worldwide communication networks.

Technique uses astronomy, opthalmology to sharpen microscope images

April 14, 2014 11:33 am | News | Comments

Biological samples bend light in unpredictable ways, returning difficult-to-interpret information to the microscope. Using a form of adaptive optics, Janelia Farm Research Campus scientists have developed a microscopy technique that can rapidly correct for distortions and sharpen high-resolution images over large volumes of tissue.

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