The combination of heat, chemotherapeutic drugs and an innovative delivery system based on nanotechnology may significantly improve the treatment of ovarian cancer while reducing side effects from toxic drugs, researchers at Oregon State Univ. report in a new study. The findings, so far done only in a laboratory setting, show that this one-two punch of mild hyperthermia and chemotherapy can kill 95% of ovarian cancer cells.
In new research, scientists have demonstrated that the efficiency of all solar panel designs could be improved by up to 22% by covering their surface with aluminium studs that bend and trap light inside the absorbing layer. At the microscopic level, the studs make the surface of the solar panels look similar to the interlocking building bricks played with by children across the world.
Life-threatening blood clots can form in anyone who sits on a plane for a long time, is confined to bed while recovering from surgery, or takes certain medications. There is no fast and easy way to diagnose these clots, which often remain undetected until they break free and cause a stroke or heart attack. However, new technology from Massachusetts Institute of Technology may soon change that.
Scientists at Rice Univ. are enhancing the natural antioxidant properties of an element found in a car’s catalytic converter to make it useful for medical applications. The team created small, uniform spheres of cerium oxide and gave them a thin coating of fatty oleic acid to make them biocompatible.
For years scientists have been working to fundamentally understand how nanoparticles move throughout the human body. One big unanswered question is how the shape of nanoparticles affects their entry into cells. Now researchers have discovered that under typical culture conditions, mammalian cells prefer disc-shaped nanoparticles over those shaped like rods.
Many viruses infect humans through mucosal surfaces. To help fight these viruses, scientists are working on vaccines that can establish a defense at mucosal surfaces. Vaccines can be delivered to the lungs via an aerosol spray, but are often cleared away before they can provoke an immune response. To overcome that, engineers have developed a new type of nanoparticle that protects the vaccine long enough to generate a strong immune response.
A new nanostructured material with applications that could include reducing condensation in airplane cabins and enabling certain medical tests without the need for high tech laboratories has been developed by researchers in Australia. The newly discovered material uses “raspberry” particles, which emulate the structure of some rose petals and can trap tiny water droplets.
A nanoparticle shaped like a spiky ball, with magnetic properties, has been uncovered in a new method of synthesizing carbon nanotubes by physicists in the U.K. The nanoparticles were discovered on the rough surfaces of a reactor designed to grow carbon nanotubes and are described as sea urchins because of their characteristic spiny appearance.
Researchers in Canada have found that abundant materials in the Earth's crust can be used to make inexpensive and easily manufactured nanoparticle-based solar cells. The team has designed nanoparticles that absorb light and conduct electricity from two very common elements: phosphorus and zinc. These are much more plentiful than scarce cadmium, and safer than lead.
Understanding what happens to a material as it undergoes phase transformations is of fundamental scientific interest. For metal nanocrystals, assumptions about the size-dependence of phase transformations were made that now need re-evaluating. A team of researchers at Lawrence Berkeley National Laboratory has demonstrated that as metal nanocrystals go through phase transformations, size can make a bigger difference than previously believed.
Over the last few years, the use of nanomaterials for water treatment, food packaging, pesticides, cosmetics and other industries has increased. A growing concern is that these particles could pose a potential health risk has prompted a large number of studies, including recent work at the Univ. of Missouri that showed the retention of silver nanoparticles in pear skin, even after repeated washing.
Cells are very good at protecting their precious contents. As a result, it’s very difficult to penetrate their membrane walls without damaging or destroying the cell. One effective way of doing so, discovered in 2008, is to use nanoparticles of pure gold, coated with a thin layer of a special polymer. But nobody knew exactly why this combination worked so well, or how it made it through the cell wall, until now.
The evolution of fluid drops deposited on solid substrates has been a focus of large research effort for decades, and most recently it has focused on nanoscale properties. Two New Jersey Institute of Technology researchers are the first to demonstrate that simulations based on continuum fluid mechanics can explain the nanoscale dynamics of liquid metal particles on a substrate.
Researchers at the Univ. of Georgia are developing a new treatment technique that uses nanoparticles to reprogram immune cells so they are able to recognize and attack cancer. The human body operates under a constant state of martial law. Chief among the enforcers charged with maintaining order is the immune system. The immune system is good at its job, but it's not perfect.
Nanocrystals can grab specific molecules and particles out the air, hold on to them and then release them. But progress in utilizing adsorption and desorption has been hindered by limitations in existing methods for measuring the physical and chemical changes that take place in individual nanocrystals. A newly developed system may solve this by directly measuring the manner in which nanocrystals adsorb and release hydrogen and other gases.
Using imperfections in diamonds as nanoscale thermometers, and gold nanoparticles implanted in cells as laser-induced heating mechanisms, a team of researchers working on DARPA’s Quantum-Assisted Sensing and Readout program recently demonstrated sub-degree temperature measurement and control at the nanometer scale inside living cells.
Tiny silicon crystals caused no health problems in monkeys three months after large doses were injected, marking a step forward in the quest to bring such materials into clinics as biomedical imaging agents, according to a new study. The findings suggest that the silicon nanocrystals, known as quantum dots, may be a safe tool for diagnostic imaging in humans.
Using gold nanoparticles, Massachusetts Institute of Technology researchers have devised a new way to turn blood clotting on and off. The particles, which are controlled by infrared laser light, could help doctors control blood clotting in patients undergoing surgery, or promote wound healing.
The properties of nanomaterials could be easier to predict in the future thanks to work by researchers who have studied metal they have ground metal continuously finer powders. They have prepared a detailed catalogue of how the structure of the metal grains changes depending on grain size, and have discovered that the crystal lattices initially shrink, but expand again below a certain threshold grain size.
By feeding stem cells tiny particles made of magnetized iron oxide, scientists at Emory Univ. and Georgia Tech have used magnets to attract the cells to a particular location in the body after intravenous injection. The method could become a tool for directing stem cells’ healing powers to treat conditions such as heart disease or vascular disease.
When studying the reactions at the catalyst surface, scientists usually have to look into idealized systems under vacuum conditions rather than examining the reality of industrial catalytic processes in a gas environment. However, new electron microscopy technology developed at the York JEOL Nanocentre in the U.K. is allowing researchers to observe and analyze single atoms and nanoparticles in dynamic in situ experiments for the first time.
Andrew Greytak, a chemist at the University of South Carolina, is leading a research team that’s making the process of synthesizing quantum dots much more systematic. His group recently detailed an effective new method for purifying cadmium selenide nanocrystals with well-defined surface properties. The advance required the adoption of gel-permeation chromatography.
Researchers have developed a concept to potentially improve delivery of drugs for cancer treatment using nanoparticles that concentrate and expand in the presence of higher acidity found in tumor cells. The concept involves using nanoparticles made of "weak polybases," compounds that expand when transported into environments mimicking tumor cells, which have a higher acidity than surrounding tissues.
The ultimate dream come true for material scientists is to have the ability to make materials that can take on properties and behaviors to best suit our needs. But scientists first must truly understand the properties of cluster assembly through the individual cluster. Now, material scientists will have greater insight into the organizing principles that allow for the design of nanoscopic materials with specific band gap energy.
A new coating technology developed at Massachusetts Institute of Technology, combined with a novel nanoparticle-manufacturing technology developed at the Univ. of North Carolina at Chapel Hill, may offer scientists a way to quickly mass-produce tailored nanoparticles that are specially coated for specific applications, including medicines and electronics.