By combining magnetic nanoparticles with one of the most common and effective chemotherapy drugs, Argonne National Laboratory researchers have created a way to deliver anti-cancer drugs directly into the nucleus of cancer cells. They have created nano-sized bubbles, or “micelles,” that contain magnetic nanoparticles of iron oxide and cisplatin, a conventional chemotherapy drug also known as “the penicillin of cancer.”
A smart technology which involves smuggling gold nanoparticles into brain cancer cells has proven highly effective in lab-based tests in the U.K. The technique could eventually be used to treat glioblastoma multiforme, which is the most common and aggressive brain tumor in adults, and notoriously difficult to treat.
A team of materials chemists, polymer scientists, device physicists and others at the Univ. of Massachusetts Amherst report a breakthrough technique for controlling molecular assembly of nanoparticles over multiple length scales that should allow faster, cheaper, more ecologically friendly manufacture of organic photovoltaics and other electronic devices.
Cancerous tumors protect themselves by tricking the immune system into accepting everything as normal, even while cancer cells are dividing and spreading. One pioneering approach to combat this effect is to use nanoparticles to jumpstart the body's ability to fight tumors. Recent combines these therapeutic nanoparticles with heat to stimulate the immune system.
By colliding ultra-small gold particles with a surface and analyzing the resulting fragments, a trio of scientists at Pacific Northwest National Laboratory discovered how and why the particles break. This information is important for controlling the synthesis of these tiny building blocks that are of interest to catalysis, energy conversion and storage, and chemical sensing.
Vibrate a solution of rod-shaped metal nanoparticles in water with ultrasound and they'll spin around their long axes like tiny drill bits. Why? No one yet knows exactly. But researchers at the NIST have clocked their speed, and it's fast. At up to 150,000 revolutions per minute, these nanomotors rotate 10 times faster than any nanoscale object submerged in liquid ever reported.
A special class of tiny gold particles can easily slip through cell membranes, making them good candidates to deliver drugs directly to target cells. A new study from Massachusetts Institute of Technology materials scientists reveals that these nanoparticles enter cells by taking advantage of a route normally used in vesicle-vesicle fusion, a crucial process that allows signal transmission between neurons.
Scientists have designed a new self-assembling nanoparticle that targets tumors, to help doctors diagnose cancer earlier. The new nanoparticle, developed by researchers in the U.K., boosts the effectiveness of magnetic resonance imaging scanning by specifically seeking out receptors that are found in cancerous cells.
A new type of catalyst, based on carbon, can facilitate two opposite reactions: electrolysis of water and combustion of hydrogen with oxygen. This bi-functionality, developed by researchers in Germany, is made possible from its construction: manganese-oxide or cobalt-oxide nanoparticles which are embedded in specially modified carbon, then integrated with nitrogen atoms in specific positions.
Located deep in the human gut, the small intestine is not easy to examine: X-rays, MRIs and ultrasound images each suffer limitations. Univ. at Buffalo researchers are developing a new imaging technique involving nanoparticles suspended in liquid to form “nanojuice” that patients would drink. Upon reaching the small intestine, doctors would strike the nanoparticles with laser light, providing a non-invasive, real-time view of the organ.
Using something called a microchannel heat sink to simulate the warm environment of a working computer, researchers in Malaysia have analyzed three nanofluids for the traits that are important in an effective coolant. The results of their study show that the nanofluids, which are made of metallic nanoparticles that have been added to a liquid, such as water, all performed better than water as coolants, with one mixture standing out.
The antibacterial properties of silver-coated textiles are popular in the fields of sport and medicine. A team in Switzerland has now investigated how different silver coatings behave in the washing machine, and they have discovered something important: textiles with nano-coatings release fewer nano-particles into the washing water than those with normal coatings.
An international team of physicists including researchers from the U.S. Naval Research Laboratory has used a scanning tunneling microscope to create quantum dots with identical, deterministic sizes. The perfect reproducibility of these dots opens the door to quantum dot architectures completely free of uncontrolled variations, an important goal for technologies from nanophotonics to quantum information processing.
You wouldn’t think that mechanical force could process nanoparticles more subtly than the most advanced chemistry. But researchers at Sandia National Laboratories have created a newly patented and original method that uses simple pressure to produce finer and cleaner results in forming silver nanostructures than do chemical methods, which are not only inflexible in their results but leave harmful byproducts.
Los Alamos National Laboratory researchers have demonstrated an almost four-fold boost of the carrier multiplication yield with nanoengineered quantum dots. Carrier multiplication is when a single photon can excite multiple electrons. Quantum dots are novel nanostructures that can become the basis of the next generation of solar cells, capable of squeezing additional electricity out of the extra energy of blue and ultraviolet photons.
Titanium dioxide nanoparticles show great promise as optical encapsulants or fillers for tunable refractive index coatings. However, they've been largely shunned because they’ve been difficult and expensive to make. Scientists at Sandia National Laboratories have now come up with an inexpensive way to synthesize properly sized titanium dioxide nanoparticles and is seeking partners who can demonstrate the process at industrial scale.
Nanoengineers at UC San Diego have developed a nanoshell to protect foreign enzymes used to starve cancer cells as part of chemotherapy. Enzymes are naturally smart machines that are responsible for many complex functions and chemical reactions in biology. However, despite their huge potential, their use in medicine has been limited by the immune system, which is designed to attack foreign intruders.
A large team of scientists have developed a “nanobarrel” molecular container that traps and concentrates light onto single molecule. These nanobarrels, which act as tiny test tubes, have been combined with gold nanoparticles so that researchers can detect what is in each one. The invention could be used as a low-cost and reliable diagnostic test.
Scientists seeking ways to engineer the assembly of tiny particles measuring just billionths of a meter have achieved a new first: the formation of a single layer of nanoparticles on a liquid surface where the properties of the layer can be easily switched. Understanding the assembly of such nanostructured thin films could lead to the design of new kinds of membranes with a variable mechanical response for a wide range of applications.
Engineers at Oregon State University have successfully shown that a continuous flow reactor can produce high-quality nanoparticles by using microwave-assisted heating. This is essentially the same force that heats up leftover food with such efficiency, but instead of warming up yesterday’s pizza, this concept may change the production of cell phones and televisions or improve solar energy systems.
One of the defining features of cells is their membranes. Each cell’s repository of DNA and protein-making machinery must be kept stable and secure from invaders and toxins. Scientists have attempted to replicate these properties, but, despite decades of research, even the most basic membrane structures, known as vesicles, still face many problems when made in the laboratory.
The days of self-assembling nanoparticles taking hours to form a film over a microscopic-sized wafer are over. Researchers with Lawrence Berkeley National Laboratory have devised a technique whereby self-assembling nanoparticle arrays can form a highly ordered thin film over macroscopic distances in one minute.
Think those flat, glassy solar panels on your neighbor’s roof are the pinnacle of solar technology? Think again. Researchers at Univ. of Toronto have designed and tested a new class of solar-sensitive nanoparticle that outshines the current state of the art employing this new class of technology.
A new nanoparticle platform developed in California increases the efficiency of drug delivery and allows excess particles to be washed away. A simple etching technique using biocompatible chemicals rapidly disassembles and removes the silver nanoparticles outside living cells. This method leaves only the intact nanoparticles for imaging or quantification, revealing which cells have been targeted and how much each cell internalized.
Atomic-scale snapshots of a bimetallic nanoparticle catalyst in action have provided insights that could help improve the industrial process by which fuels and chemicals are synthesized from natural gas, coal or plant biomass. A multinational laboratory collaboration has taken the most detailed look ever at the evolution of platinum/cobalt bimetallic nanoparticles during reactions in oxygen and hydrogen gases.