Conventional treatment seeks to eradicate cancer cells by drugs and therapy delivered from outside the cell, which may also affect (and potentially harm) nearby normal cells. In contrast to conventional cancer therapy, a Univ. of Cincinnati team has developed several novel designs for iron-oxide based nanoparticles that detect, diagnose and destroy cancer cells using photo-thermal therapy (PTT).
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In an international study Univ. of Melbourne and NIST found that pairs of closely spaced nanoparticles made of gold can act as “optical antennas”. These antennae concentrate the light shining on them into tiny regions located in the gap between the nanoparticles. Researchers found the precise geometry of nanoparticle pairs that maximizes light concentration, resolving a hotly debated area of quantum physics.
With fears growing over chemical and biological weapons falling into the wrong hands, scientists are developing microrockets to fight back against these dangerous agents, should the need arise. In ACS Nano, they describe new spherical micromotors that rapidly neutralize chemical and biological agents and use water as fuel.
Researching the safety of nanoparticles is all the rage. Thousands of scientists worldwide are conducting research on the topic, examining the question of whether titanium dioxide nanoparticles or carbon nanotubes can get into the body’s lungs or blood. However, the amount of new knowledge has only increased marginally. How do nanoparticles get into the body? Researchers in Switzerland are attempting to establish standards.
A group of scientists in Florida have combined medicine and advanced nanotechnological engineering to create a smarter, more targeted therapy that could overcome the most lethal gynecologic cancer. The technology involves combining Taxol, a chemotherapy drug, with magneto-electric nanoparticles that can penetrate the blood-brain barrier.
Scientists at Ames Laboratory have developed deeper understanding of the ideal design for mesoporous nanoparticles used in catalytic reactions, such as hydrocarbon conversion to biofuels. The research will help determine the optimal diameter of channels within the nanoparticles to maximize catalytic output.
Some people might consider mucus an icky bodily secretion best left wrapped in a tissue, but to a group of researchers in North Carolina, snot is an endlessly fascinating subject. The team has developed a way to use gold nanoparticles and light to measure the stickiness of the slimy substance that lines our airways. The new method could help doctors better monitor and treat lung diseases such as cystic fibrosis.
A surprising phenomenon has been found in metal nanoparticles: They appear, from the outside, to be liquid droplets, wobbling and readily changing shape, while their interiors retain a perfectly stable crystal configuration. The research team behind the finding says the work could have important implications for the design of components in nanotechnology, such as metal contacts for molecular electronic circuits.
Using a common laboratory filter paper decorated with gold nanoparticles, researchers at Washington Univ. in St. Louis have created a unique platform, known as “plasmonic paper,” for detecting and characterizing even trace amounts of chemicals and biologically important molecules, including explosives, chemical warfare agents, environmental pollutants and disease markers.
A long-sought goal of creating particles that can emit a colorful fluorescent glow in a biological environment, and that could be precisely manipulated into position within living cells, has been achieved by a team of researchers at Massachusetts Institute of Technology and several other institutions. The new technology could make it possible to track the position of the nanoparticles as they move within the body or inside a cell.
A proposal to develop a new way to remotely control brain cells from Sarah Stanley, a research associate in Rockefeller Univ.’s Laboratory of Molecular Genetics is among the first to receive funding from President Barack Obama’s BRAIN initiative. The project will make use of a technique called radiogenetics that combines the use of radio waves or magnetic fields with nanoparticles to turn neurons on or off.
Nanoparticles could revolutionize the medical industry, but they must first target a specific region in the body, be trackable, and perform their function at the right moment. Researchers in Japan have made progress in this direction with a new type of nanomaterial: the nanosheet. Specifically, they have designed a strong, stable and optically traceable smart 2-D material that responds to pH, or the acidity or basicity of its environment.
At the Vienna Univ. of Technology gold nanoparticles have been coupled to a glass fiber. The particles emit light into the fiber in such a way that it does not travel in both directions, as one would expect. Instead, the light can be directed either to the left or to the right. This became possible by employing the spin-orbit coupling of light, creating a new kind of optical switch that has the potential to revolutionize nanophotonics.
A Duke Univ. team has found that nanoparticles called single-walled carbon nanotubes accumulate quickly in the bottom sediments of an experimental wetland setting, an action they say could indirectly damage the aquatic food chain. According to the research, the risk to humans ingesting the particles through drinking water is slight, but aquatic food chains might be harmed by molecules "piggybacking" on the carbon nanoparticles.
Cancer vaccines have recently emerged as a promising approach for killing tumor cells before they spread. But so far, most clinical candidates haven’t worked that well. Now, scientists have developed a new way to deliver vaccines that successfully stifled tumor growth when tested in laboratory mice. And the key is in the vaccine’s unique stealthy nanoparticles.
Graphene quantum dots created at Rice Univ. grab onto graphene platelets like barnacles attach themselves to the hull of a boat. But these dots enhance the properties of the mothership, making them better than platinum catalysts for certain reactions within fuel cells.
The excessive atmospheric carbon dioxide that is driving global climate change could be harnessed into a renewable energy technology that would be a win for both the environment and the economy. That is the lure of artificial photosynthesis in which the electrochemical reduction of carbon dioxide is used to produce clean, green and sustainable fuels.
If it's true that good things come in small packages, then NIST can now make anyone working with nanoparticles very happy. The institute recently issued Reference Material (RM) 8027, the smallest known reference material ever created for validating measurements of man-made, ultrafine particles between 1 and 100 nm in size.
Scientists at the U.S. Naval Research Laboratory have introduced a new one-step process using, for the first time in these types of syntheses, potassium superoxide to rapidly form oxide nanoparticles from simple salt solutions in water. An important advantage of this method is the capability of creating bulk quantities of these materials, more than 10 g in a single step.
Transforming substances from liquids into gels plays an important role across many industries, but the transformation process, called gelation, is expensive and energy demanding. Instead of adding chemical thickeners and heating or cooling the fluids, as is traditional, researchers in Okinawa are experimenting with microfluidic platforms, adding nanoparticles and biomolecules with used pH, chemical and temperature sensing properties.
One sip of a perfectly poured glass of wine leads to an explosion of flavors in your mouth. Researchers in Denmark have now developed a nanosensor that can mimic what happens in your mouth when you drink wine. The sensor, which uses gold nanoparticles to act as a “mini-mouth”, measures how you experience the sensation of dryness in the wine.
The quest to create artificial “squid skin”—camouflaging metamaterials that can “see” colors and automatically blend into the background—is one step closer to reality, thanks to a breakthrough color-display technology unveiled by Rice Univ. The new full-color display technology uses aluminum nanoparticles to create the vivid red, blue and green hues found in today’s top-of-the-line LCD televisions and monitors.
For detecting cancer, manual breast exams seem low-tech compared to other methods such as MRI. But scientists are now developing an “electronic skin” that “feels” and images small lumps that fingers can miss. Knowing the size and shape of a lump could allow for earlier identification of breast cancer, which could save lives.
When it comes to diesel engine catalysts, which are responsible for cleansing exhaust fumes, platinum has unfortunately proved to be the only viable option. This has resulted in material costs alone accounting for half of the price of a diesel catalyst. Researchers in Denmark say they have developed a new way to manufacture catalysts that may result in a 25% reduction in the use of platinum.
A team of researchers in the U.S. and China have developed a new sensor that can detect and count nanoparticles, at sizes as small as 10 nm, one at a time. The researchers say the sensor, which is a Raman microlaser sensor in a silicon dioxide chip that does not need rare-earth ions to achieve high resolution, could potentially detect much smaller particles, viruses and small molecules.
Scientists at Yale Univ. have developed a novel cancer immunotherapy that rapidly grows and enhances a patient’s immune cells outside the body using carbon nanotube-polymer composites; the immune cells can then be injected back into a patient’s blood to boost the immune response or fight cancer.
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