Carnegie Mellon University chemists have developed two novel methods to characterize 3-dimensional macroporous hydrogels -- materials that hold great promise for developing "smart" responsive materials that can be used for catalysts, chemical detectors, tissue engineering scaffolds and absorbents for carbon capture.
From gummy bears to silky mousses, gelatin is essential for making some of our favorite sweets....
Anything you can do, nature can do better. Chemical delivery systems, self-healing cells, non-...
The electromagnetic radiation discharged by electronic equipment and devices is known to hinder their smooth operation. Conventional materials used today to shield from incoming electromagnetic waves tend to be sheets of metal or composites, which rely on reflection as a shielding mechanism.
Researchers from the Univ. of California, Los Angeles have developed an injectable hydrogel that helps skin wounds heal more quickly. The material creates an instant scaffold that allows new tissue to latch on and grow within the cavities formed between linked spheres of gel.
Researchers have developed a new way of making tough, but soft and wet, biocompatible materials, called “hydrogels,” into complex and intricately patterned shapes. The process might lead to injectable materials for delivering drugs or cells into the body; scaffolds for regenerating load-bearing tissues; or tough but flexible actuators for future robots, the researchers say.
Nanoengineers at the Univ. of California, San Diego developed a gel filled with toxin-absorbing nanosponges that could lead to an effective treatment for skin and wound infections caused by MRSA, an antibiotic-resistant bacteria. This "nanosponge-hydrogel" minimized the growth of skin lesions on mice infected with MRSA, without the use of antibiotics.
For decades, robots have advanced the efficiency of human activity. Typically, however, robots are formed from bulky, stiff materials and require connections to external power sources; these features limit their dexterity and mobility. But what if a new material would allow for development of a "soft robot" that could reconfigure its own shape and move using its own internally generated power?
If you opt to wear soft contact lenses, chances are you are using hydrogels on a daily basis. Made up of polymer chains that are able to absorb water, hydrogels used in contacts are flexible and allow oxygen to pass through the lenses, keeping eyes healthy. Hydrogels can be up to 99% water and as a result are similar in composition to human tissues.
A new type of graphene aerogel will make for better energy storage, sensors, nanoelectronics, catalysis and separations. Lawrence Livermore National Laboratory researchers have made graphene aerogel microlattices with an engineered architecture via a 3D printing technique known as direct ink writing.
Scientists are using stem cells from amniotic fluid to promote the growth of functional blood vessels in healing hydrogels. In new experiments, the scientists combined versatile amniotic stem cells with injectable hydrogels used as scaffolds in regenerative medicine and proved they enhance the development of vessels needed to bring blood to new tissue and carry waste products away.
Rice Univ. scientists have found the balance necessary to aid healing with high-tech hydrogel. The team created a new version of the hydrogel that can be injected into an internal wound and help it heal while slowly degrading as it is replaced by natural tissue. Hydrogels are used as a scaffold upon which cells can build tissue. The new hydrogel overcomes a host of issues that have kept them from reaching their potential to treat injuries.
Stroke victims could have more time to seek treatment that could reduce harmful effects on the brain, thanks to tiny blobs of gelatin that could deliver the medication to the brain noninvasively. Univ. of Illinois researchers found that gelatin nanoparticles could be laced with medications for delivery to the brain, and that they could extend the treatment window for when a drug could be effective.
Transforming substances from liquids into gels plays an important role across many industries, but the transformation process, called gelation, is expensive and energy demanding. Instead of adding chemical thickeners and heating or cooling the fluids, as is traditional, researchers in Okinawa are experimenting with microfluidic platforms, adding nanoparticles and biomolecules with used pH, chemical and temperature sensing properties.
Univ. of Illinois engineers are bringing a touch of color to glucose monitoring. The researchers developed a new continuous glucose monitoring material that changes color as glucose levels fluctuate, and the wavelength shift is so precise that doctors and patients may be able to use it for automatic insulin dosing—something now possible using current point measurements like test strips.
Current drug delivery systems used to administer chemotherapy to cancer patients typically release a constant dose of the drug over time, but a new study challenges this "slow and steady" approach and offers a novel way to locally deliver the drugs "on demand," as reported in the Proceedings of the National Academy of Sciences.
When stem cells are used to regenerate bone tissue, many wind up migrating away from the repair site, which disrupts the healing process. But a technique employed by a Univ. of Rochester research team keeps the stem cells in place, resulting in faster and better tissue regeneration. The keyis encasing the stem cells in polymers that attract water and disappear when their work is done.
Rice Univ. bioengineers have created a hydrogel that instantly turns from liquid to semisolid at close to body temperature—and then degrades at precisely the right pace. The gel shows potential as a bioscaffold to support the regrowth of bone and other 3-D tissues in a patient’s body using the patient’s own cells to seed the process.
Stem cells have the potential to repair human tissue and maintain organ function in chronic disease, but a major problem has been how to mass-produce such a complex living material. Scientists in the U.K. have now developed a new substance which could simplify the manufacture of therapeutic cells by allowing both self-renewal of cells and evolution into cardiomyocyte cells.
Combatting the tissue degrading enzymes that cause lasting damage following a heart attack is tricky. Each patient responds to a heart attack differently and damage can vary from one part of the heart muscle to another, but existing treatments can’t be fine-tuned to deal with this variation. Univ. of Pennsylvania researchers have developed a way to address this problem via a material that can be applied directly to the damaged heart tissue.
A bit of pressure from a new shrinking, sponge-like gel is all it takes to turn transplanted unspecialized cells into cells that lay down minerals and begin to form teeth. The bioinspired gel material could one day help repair or replace damaged organs, such as teeth and bone, and possibly other organs as well.
Protein from a small, tasty mollusk inspired Michigan Technological Univ.’s Bruce P. Lee to invent a new type of hydrogel actuator. Hydrogels are soft networks of polymers with high water content, like jello. Because of their soft, gentle texture, they have the potential to interact safely with living tissues and have applications in a number of medical areas, including tissue engineering.
A group of Washington State Univ. researchers has developed a chewing gum-like battery material that could dramatically improve the safety of lithium-ion batteries. High-performance lithium batteries are popular in everything from computers to airplanes because they are able to store a large amount of energy compared to other batteries. Their biggest potential risk, however, comes from the electrolyte in the battery.
Researchers at the Univ. of Delaware have developed a “smart” hydrogel that can deliver medicine on demand, in response to mechanical force. Over the past few decades, smart hydrogels have been created that respond to pH, temperature, DNA, light and other stimuli.
A Duke Univ. research team has developed a better recipe for synthetic replacement cartilage in joints. Combining two innovative technologies, the team found a way to create artificial replacement tissue that mimics both the strength and suppleness of native cartilage. Articular cartilage is the tissue on the ends of bones where they meet at joints in the body.
A research team in France has invented an adhesion method that creates a strong bond between two gels by spreading on their surface a solution containing nanoparticles. Until now, there was no entirely satisfactory method of obtaining adhesion between two gels or two biological tissues. The bond is resistant to water and uses no polymers or chemical reactions.
Rice Univ. bioengineers have developed a hydrogel scaffold for craniofacial bone tissue regeneration that starts as a liquid, solidifies into a gel in the body and liquefies again for removal. The material developed in a Rice laboratory is a soluble liquid at room temperature that can be injected to the point of need. At body temperature, it turns into a gel to help direct the formation of new bone to replace that damaged by injury.
Scientists are reporting development of a squishy gel that, when compressed at a key location such as a painful knee joint, releases anti-inflammatory medicine. The new material could someday deliver medications when and where osteoarthritis patients need it most.
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