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Biomaterials
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The Lead

DNA “glue” could be used to build tissues, organs

January 14, 2015 10:23 am | by American Chemical Society | News | Comments

DNA molecules provide the "source code" for life in humans, plants, animals and some microbes. But now researchers report an initial study showing that the strands can also act as a glue to hold together 3-D-printed materials that could someday be used to grow tissues and organs in the laboratory.

A potential long-lasting treatment for sensitive teeth

January 8, 2015 9:22 am | by American Chemical Society | News | Comments

Rather than soothe and comfort, a hot cup of tea or cocoa can cause people with sensitive teeth...

Honeybee hive sealant promotes hair growth in mice

January 7, 2015 2:58 pm | by American Chemical Society | News | Comments

Hair loss can be devastating for the millions of men and women who experience it. Now scientists...

Responsive material could be the “golden ticket” of sensing

January 7, 2015 7:45 am | by Univ. of Cambridge | News | Comments

Researchers from the Univ. of Cambridge have developed a new self-assembled material, which, by...

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Bio-inspired bleeding control

November 13, 2014 4:12 pm | by Sonia Fernandez, Univ. of California, Santa Barbara | News | Comments

Stanching the free flow of blood from an injury remains a holy grail of clinical medicine. Controlling blood flow is a primary concern and first line of defense for patients and medical staff in many situations, from traumatic injury to illness to surgery. If control is not established within the first few minutes of a hemorrhage, further treatment and healing are impossible.

'Direct writing' of diamond patterns from graphite a potential technological leap

November 6, 2014 10:00 am | by Emil Venere, Purdue Univ. | News | Comments

What began as research into a method to strengthen metals has led to the discovery of a new technique that uses a pulsing laser to create synthetic nanodiamond films and patterns from graphite, with potential applications from biosensors to computer chips.

Making lab-grown tissues stronger

October 31, 2014 8:54 am | by Andy Fell, UC Davis News Service | News | Comments

Lab-grown tissues could one day provide new treatments for injuries and damage to the joints, including articular cartilage, tendons and ligaments. Cartilage, for example, is a hard material that caps the ends of bones and allows joints to work smoothly. Univ. of California, Davis biomedical engineers, exploring ways to toughen up engineered cartilage and keep natural tissues strong outside the body, report new developments.

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“Sticky” ends start synthetic collagen growth

October 28, 2014 8:12 am | by Mike Williams, Rice Univ. | News | Comments

Rice Univ. researchers have delivered a scientific one-two punch with a pair of papers that detail how synthetic collagen fibers self-assemble via their sticky ends. Collagen is the most common protein in mammals, a major component of bone and the fibrous tissues that support cells and hold organs together. Discovering its secrets may lead to better synthetic collagen for tissue engineering and cosmetic and reconstructive medicine.

Emergent behavior lets bubbles “sense” environment

October 27, 2014 12:46 pm | Videos | Comments

Tiny, soapy bubbles can reorganize their membranes to let material flow in and out in response to the surrounding environment, according to new research. This behavior could be exploited in creating microbubbles that deliver drugs or other payloads inside the body, and could help us understand how the very first living cells on Earth might have survived billions of years ago.

Breaking the nano barrier

October 24, 2014 8:00 am | by New York Univ. | News | Comments

Researchers at the New York Univ. Polytechnic School of Engineering have broken new ground in the development of proteins that form specialized fibers used in medicine and nanotechnology. For as long as scientists have been able to create new proteins that are capable of self-assembling into fibers, their work has taken place on the nanoscale. For the first time, this achievement has been realized on the microscale.

Platelets modulate clotting behavior by “feeling” their surroundings

September 25, 2014 8:31 am | by John Toon, Georgia Institute of Technology | News | Comments

Platelets, the tiny cell fragments whose job it is to stop bleeding, are very simple. They don’t have a cell nucleus. But they can “feel” the physical environment around them, researchers at Emory Univ. and Georgia Tech have discovered. Platelets respond to surfaces with greater stiffness by increasing their stickiness, the degree to which they “turn on” other platelets and other components of the clotting system, the researchers found.

Engineered proteins stick like glue, even in water

September 22, 2014 1:46 pm | by Anne Trafton, MIT | News | Comments

Shellfish such as mussels and barnacles secrete very sticky proteins that help them cling to rocks or ship hulls, even underwater. Inspired by these natural adhesives, a team of Massachusetts Institute of Technology engineers has designed new materials that could be used to repair ships or help heal wounds and surgical incisions.

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“Electronic skin” could improve early breast cancer detection

September 10, 2014 1:09 pm | News | Comments

For detecting cancer, manual breast exams seem low-tech compared to other methods such as MRI. But scientists are now developing an “electronic skin” that “feels” and images small lumps that fingers can miss. Knowing the size and shape of a lump could allow for earlier identification of breast cancer, which could save lives.

New "dry" process creates artificial membranes on silicon

September 9, 2014 2:42 pm | News | Comments

Artificial membranes mimicking those found in living organisms have many potential applications ranging from detecting bacterial contaminants in food to toxic pollution in the environment to dangerous diseases in people. Now a group of scientists in Chile has developed a way to create these delicate, ultra-thin constructs through a "dry" process, by evaporating two commercial, off-the-shelf chemicals onto silicon surfaces.

Platelet-like particles augment natural blood clotting for treating trauma

September 8, 2014 8:23 am | by John Toon, Georgia Institute of Technology | News | Comments

A new class of synthetic platelet-like particles could augment natural blood clotting for the emergency treatment of traumatic injuries. The clotting particles, which are based on soft and deformable hydrogel materials, are triggered by the same factor that initiates the body’s own clotting processes.

The beetle’s white album

August 15, 2014 9:31 am | News | Comments

The physical properties of the ultra-white scales on certain species of beetle could be used to make whiter paper, plastics and paints, while using far less material than is used in current manufacturing methods. Current technology is not able to produce a coating as white as these beetles can in such a thin layer, and spectroscopic analyses are revealing how this colorization is achieved through a dense complex network of chitin.

World’s smallest propeller could be used for microscopic medicine

July 30, 2014 9:29 am | by Kevin Hattori, American Technion Society | News | Comments

An Israeli and German research team have succeeded in creating a tiny screw-shaped propeller that can move in a gel-like fluid, mimicking the environment inside a living organism. The filament that makes up the propeller, made of silica and nickel, is only 70 nm in diameter. The entire propeller is just 400 nm long.

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Antioxidant biomaterial promotes healing

July 25, 2014 6:55 am | News | Comments

When a foreign material like a medical device or surgical implant is put inside the human body, the body usually reacts negatively. For the first time ever, researchers at Northwestern Univ. have created a biodegradable biomaterial that is inherently antioxidant. The material can be used to create elastomers, liquids that turn into gels, or solids for building devices that are more compatible with cells and tissues.

Ultrasonically propelled nanorods spin dizzyingly fast

July 22, 2014 8:32 am | News | Comments

Vibrate a solution of rod-shaped metal nanoparticles in water with ultrasound and they'll spin around their long axes like tiny drill bits. Why? No one yet knows exactly. But researchers at the NIST have clocked their speed, and it's fast. At up to 150,000 revolutions per minute, these nanomotors rotate 10 times faster than any nanoscale object submerged in liquid ever reported.

Mats made from shrimp chitin attract uranium like a magnet

July 18, 2014 11:16 am | News | Comments

A Univ. of Alabama start-up company, 525 Solutions, has received about $1.5 million from the federal government to refine an invention to extract uranium from the ocean for use as fuel. It is an adsorbent, biodegradable material made from the compound chitin, which is found in crustaceans and insects. The researchers have developed transparent sheets, or mats, comprised of tiny chitin fibers, which pull uranium from the water.

Study: Squid skin protein could improve biomedical technologies

July 16, 2014 2:24 pm | News | Comments

The common pencil squid may hold the key to a new generation of medical technologies that could communicate more directly with the human body. Materials science researchers in California have discovered that reflectin, a protein in the tentacled creature’s skin, can conduct positive electrical charges, or protons, making it a promising material for building biologically inspired devices.  

Researchers develop smart gating nanochannels for confined water

June 25, 2014 11:14 am | News | Comments

Confined water exists widely and plays important roles in natural environments, particularly inside biological nanochannels. After several years of work, scientists in China have developed a series of biomimetic nanochannels that can serve as the base for confined transportation of water. The technology suggests a potential use in energy conversion systems.

Delivering drugs on cue

June 24, 2014 7:43 am | News | Comments

Current drug delivery systems used to administer chemotherapy to cancer patients typically release a constant dose of the drug over time, but a new study challenges this "slow and steady" approach and offers a novel way to locally deliver the drugs "on demand," as reported in the Proceedings of the National Academy of Sciences.

Better tissue healing with disappearing hydrogels

June 9, 2014 8:06 am | by Peter Iglinski, Univ. of Rochester | News | Comments

When stem cells are used to regenerate bone tissue, many wind up migrating away from the repair site, which disrupts the healing process. But a technique employed by a Univ. of Rochester research team keeps the stem cells in place, resulting in faster and better tissue regeneration. The keyis encasing the stem cells in polymers that attract water and disappear when their work is done.

Joint implants without an expiration date

June 2, 2014 9:02 am | News | Comments

Artificial joints have a limited lifespan. After a few years, many hip and knee joints have to be replaced. More problematic are intervertebral disc implants, which cannot easily be replaced after they “expire” and are usually reinforced, which restrict a patient’s movement. Researchers in Switzlernad have now succeeded in coating mobile intervertebral disc implants so that they show no wear and will now last for a lifetime.

Engineering a better way to rebuild bone inside the body

May 30, 2014 8:05 am | by Brett Israel, Georgia Institute of Technology | News | Comments

Traumatic bone injuries are often so severe that the body can’t effectively repair the damage on its own. To aid the recovery, clinicians inject patients with growth factors. The treatment is costly, requiring large amounts of expensive growth factors. The growth factors also disperse, creating unwanted bone formation around the injury. A new technology could provide more efficient delivery of the bone regenerating growth factors.

Study finds crowding has big effects on biomolecules

May 22, 2014 1:58 pm | News | Comments

Crowding has notoriously negative effects at large size scales, blamed for everything from human disease and depression to community resource shortages. But relatively little is known about the influence of crowding at the cellular level. A new JILA study shows that a crowded environment has dramatic effects on individual biomolecules.

Using nature as a model for low-friction bearings

May 14, 2014 9:30 am | News | Comments

The mechanical properties of natural joints are considered unrivalled. Cartilage is coated with a special polymer layer allowing joints to move virtually friction-free, even under high pressure. Using simulations, scientists in Europe have developed a new process that technologically imitates biological lubrication and even improves it using two different types of polymers.

A hydrogel that knows when to go

May 7, 2014 7:34 am | Videos | Comments

Rice Univ. bioengineers have created a hydrogel that instantly turns from liquid to semisolid at close to body temperature—and then degrades at precisely the right pace. The gel shows potential as a bioscaffold to support the regrowth of bone and other 3-D tissues in a patient’s body using the patient’s own cells to seed the process.

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