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The Lead

Ultrasonically propelled nanorods spin dizzyingly fast

July 22, 2014 8:32 am | News | Comments

Vibrate a solution of rod-shaped metal nanoparticles in water with ultrasound and they'll spin around their long axes like tiny drill bits. Why? No one yet knows exactly. But researchers at the NIST have clocked their speed, and it's fast. At up to 150,000 revolutions per minute, these nanomotors rotate 10 times faster than any nanoscale object submerged in liquid ever reported.

Mats made from shrimp chitin attract uranium like a magnet

July 18, 2014 11:16 am | News | Comments

A Univ. of Alabama start-up company, 525 Solutions...

Study: Squid skin protein could improve biomedical technologies

July 16, 2014 2:24 pm | News | Comments

The common pencil squid may hold the key to a new...

Researchers develop smart gating nanochannels for confined water

June 25, 2014 11:14 am | News | Comments

Confined water exists widely and plays important...

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Delivering drugs on cue

June 24, 2014 7:43 am | News | Comments

Current drug delivery systems used to administer chemotherapy to cancer patients typically release a constant dose of the drug over time, but a new study challenges this "slow and steady" approach and offers a novel way to locally deliver the drugs "on demand," as reported in the Proceedings of the National Academy of Sciences.

Better tissue healing with disappearing hydrogels

June 9, 2014 8:06 am | by Peter Iglinski, Univ. of Rochester | News | Comments

When stem cells are used to regenerate bone tissue, many wind up migrating away from the repair site, which disrupts the healing process. But a technique employed by a Univ. of Rochester research team keeps the stem cells in place, resulting in faster and better tissue regeneration. The keyis encasing the stem cells in polymers that attract water and disappear when their work is done.

Joint implants without an expiration date

June 2, 2014 9:02 am | News | Comments

Artificial joints have a limited lifespan. After a few years, many hip and knee joints have to be replaced. More problematic are intervertebral disc implants, which cannot easily be replaced after they “expire” and are usually reinforced, which restrict a patient’s movement. Researchers in Switzlernad have now succeeded in coating mobile intervertebral disc implants so that they show no wear and will now last for a lifetime.

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Engineering a better way to rebuild bone inside the body

May 30, 2014 8:05 am | by Brett Israel, Georgia Institute of Technology | News | Comments

Traumatic bone injuries are often so severe that the body can’t effectively repair the damage on its own. To aid the recovery, clinicians inject patients with growth factors. The treatment is costly, requiring large amounts of expensive growth factors. The growth factors also disperse, creating unwanted bone formation around the injury. A new technology could provide more efficient delivery of the bone regenerating growth factors.

Study finds crowding has big effects on biomolecules

May 22, 2014 1:58 pm | News | Comments

Crowding has notoriously negative effects at large size scales, blamed for everything from human disease and depression to community resource shortages. But relatively little is known about the influence of crowding at the cellular level. A new JILA study shows that a crowded environment has dramatic effects on individual biomolecules.

Using nature as a model for low-friction bearings

May 14, 2014 9:30 am | News | Comments

The mechanical properties of natural joints are considered unrivalled. Cartilage is coated with a special polymer layer allowing joints to move virtually friction-free, even under high pressure. Using simulations, scientists in Europe have developed a new process that technologically imitates biological lubrication and even improves it using two different types of polymers.

A hydrogel that knows when to go

May 7, 2014 7:34 am | Videos | Comments

Rice Univ. bioengineers have created a hydrogel that instantly turns from liquid to semisolid at close to body temperature—and then degrades at precisely the right pace. The gel shows potential as a bioscaffold to support the regrowth of bone and other 3-D tissues in a patient’s body using the patient’s own cells to seed the process.

Cyborg sensor could unlock anesthesia’s secrets

May 6, 2014 11:19 am | by Evan Lerner, Univ. of Pennsylvania | News | Comments

Researchers in Pennsylvania have created an artificial chemical sensor based on one of the human body’s most important receptors, one that is critical in the action of painkillers and anesthetics. In these devices, the receptors’ activation produces an electrical response rather than a biochemical one, allowing that response to be read out by a computer.

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Engineers grow functional human cartilage in lab

April 30, 2014 2:50 pm | by Holly Evarts, Columbia Engineering | News | Comments

Researchers in New York have been able to, for the first time, generate fully functional human cartilage from mesenchymal stem cells by mimicking, in vitro, the developmental process of mesenchymal condensation. While there has been great success in engineering pieces of cartilage using young animal cells, no one has, until now, been able to reproduce these results using adult human stem cells from bone marrow or fat.

Promising agents burst through superbug defenses to fight antibiotic resistance

April 10, 2014 9:02 am | News | Comments

In the fight against “superbugs,” scientists have discovered a class of agents that can make some of the most notorious strains vulnerable to the same antibiotics that they once handily shrugged off. Recently discovered metallopolymers, when paired with the same antibiotics MRSA normally dispatches with ease, helped evade the bacteria’s defensive enzymes and destroyed its protective walls, causing the bacteria to burst.

Synthetic collagen promotes natural clotting

April 10, 2014 8:04 am | News | Comments

Synthetic collagen invented at Rice Univ. may help wounds heal by directing the natural clotting of blood. The material, KOD, mimics natural collagen, a fibrous protein that binds cells together into organs and tissues. It could improve upon commercial sponges or therapies based on naturally derived porcine or bovine-derived collagen now used to aid healing during or after surgery.

An ultrathin collagen matrix biomaterial tool for 3-D microtissue engineering

April 3, 2014 9:53 am | by World Scientific | News | Comments

A novel ultrathin collagen matrix assembly allows for the unprecedented maintenance of liver cell morphology and function in a microscale "organ-on-a-chip" device that is one example of 3-D microtissue engineering.          

Lab-grown muscle heals itself after animal implantation

April 2, 2014 12:07 pm | News | Comments

Biomedical engineers have grown living skeletal muscle that looks a lot like the real thing. It contracts powerfully and rapidly, integrates into mice quickly, and for the first time, demonstrates the ability to heal itself both inside the laboratory and inside an animal.

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Researchers uncover secrets of a mollusk’s bioceramic armor

March 31, 2014 7:43 am | by David L. Chandler, MIT News Office | News | Comments

The shells of a sea creature, the mollusk Placuna placenta, are not only exceptionally tough, but also clear enough to read through. Now, researchers at Massachusetts Institute of Technology have analyzed these shells to determine exactly why they are so resistant to penetration and damage; even though they are 99% calcite, a weak, brittle mineral.

World’s first light-activated antimicrobial surface also works in the dark

March 24, 2014 3:46 pm | News | Comments

Researchers in the U.K. have developed a new antibacterial material which has potential for cutting hospital acquired infections. The combination of two simple dyes with nanoscopic particles of gold is deadly to bacteria when activated by light, even under modest indoor lighting. And in a first for this type of substance, it also shows impressive antibacterial properties in total darkness.

Bionic plants

March 17, 2014 7:36 am | by Anne Trafton, MIT News Office | News | Comments

Plants have many valuable functions: They provide food and fuel, release the oxygen that we breathe and add beauty to our surroundings. Now, a team of Massachusetts Institute of Technology researchers wants to make plants even more useful by augmenting them with nanomaterials that could enhance their energy production and give them completely new functions, such as monitoring environmental pollutants.

Scientists “herd” cells in new approach to tissue engineering

March 12, 2014 8:08 am | by Sarah Yang, Media Relations, UC Berkeley | Videos | Comments

Sometimes it only takes a quick jolt of electricity to get a swarm of cells moving in the right direction. Researchers at the Univ. of California, Berkeley found that an electrical current can be used to orchestrate the flow of a group of cells, an achievement that could establish the basis for more controlled forms of tissue engineering.

Manufacturing a solution to planet-clogging plastics

March 7, 2014 9:06 am | by Kristen Kusek, Wyss Institute for Biologically Inspired Engineering, Harvard Univ. | News | Comments

Researchers at Harvard Univ.'s Wyss Institute have developed a method to carry out large-scale manufacturing of everyday objects using a fully degradable bioplastic isolated from shrimp shells. The objects exhibit many of the same properties as those created with synthetic plastics, but without the environmental threat. It also trumps most bioplastics on the market today in posing absolutely no threat to trees.

Shrinking gel steers tooth tissue formation

March 6, 2014 9:02 am | by Dan Ferber, Wyss Institute for Biologically Inspired Engineering, Harvard Univ. | News | Comments

A bit of pressure from a new shrinking, sponge-like gel is all it takes to turn transplanted unspecialized cells into cells that lay down minerals and begin to form teeth. The bioinspired gel material could one day help repair or replace damaged organs, such as teeth and bone, and possibly other organs as well.

Pumping iron: A hydrogel actuator with mussel tone

March 6, 2014 8:48 am | by Marcia Goodrich, Michigan Technological Univ. | News | Comments

Protein from a small, tasty mollusk inspired Michigan Technological Univ.’s Bruce P. Lee to invent a new type of hydrogel actuator. Hydrogels are soft networks of polymers with high water content, like jello. Because of their soft, gentle texture, they have the potential to interact safely with living tissues and have applications in a number of medical areas, including tissue engineering.

Andor Technology joins Oxford Instruments to drive growth

February 12, 2014 8:57 am | News | Comments

Oxford Instruments, a leading provider of high-technology tools for industry and research has recently acquired Andor. A supplier of high-performance cameras, microscope systems and software for the physical science and life science industries, Andor will continue to focus on growing its existing core markets and will spearhead Oxford Instruments strategic expansion into the nanobiotechnology arena.

Lungs may suffer when certain elements go nano

January 28, 2014 11:40 am | by Linda Fulps, Missouri Science & Technology | News | Comments

More than 2,800 commercially available applications are now based on nanoparticles, but this influx of nanotechnology is not without risks, say researchers at Missouri Univ. of Science and Technology. They have been systematically studying the effects of transition metal oxide nanoparticles on human lung cells and have found that the nanoparticles’ toxicity to the cells increased as they moved right on the periodic table.

Silk coat for diamonds makes sleek new imaging, drug delivery tool

January 27, 2014 2:12 pm | News | Comments

Silk and diamonds aren't just for ties and jewelry anymore. They're ingredients for a new kind of tiny glowing particle that could provide doctors and researchers with a novel technique for biological imaging and drug delivery. Just tens of nanometers across, the new particles are made of diamond, covered in silk and can be injected into living cells.

Seashells inspire new way to preserve bones for archeologists, paleontologists

January 22, 2014 9:04 am | News | Comments

Recreating the story of humanity’s past by studying ancient bones can hit a snag when they deteriorate, but scientists are now reporting an advance inspired by seashells that can better preserve valuable remains. Their findings, which appear in Langmuir, could have wide-ranging implications for both archeology and paleontology.

Researchers develop artificial bone marrow

January 10, 2014 12:51 pm | News | Comments

A new porous structure under development in German possesses essential properties of natural bone marrow and can be used for the reproduction of stem cells in the laboratory. The specific reproduction of these hematopoietic cells outside the body might facilitate new therapies for leukemia in a few years.

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