Researchers at the RIKEN-MIT Center for Neural Circuit Genetics and Massachusetts Institute of Technology's Picower Institute for Learning and Memory have used optogenetics techniques to implant false memories into mice, potentially illuminating the mechanisms underlying the human phenomenon of “recalling” experiences that never occurred.
Scientists have developed an "intelligent knife" that can tell surgeons immediately whether the tissue they are cutting is cancerous or not. In the first study to test the invention in the operating theatre, the "iKnife" diagnosed tissue samples from 91 patients with 100% accuracy, instantly providing information that normally takes up to half an hour to reveal using laboratory tests.
Half a millennium after Johannes Gutenberg printed the Bible, researchers printed a 3-D splint that saved the life of an infant born with severe tracheobronchomalacia, a birth defect that causes the airway to collapse. While similar surgeries have been performed using tissue donations and windpipes created from stem cells, this is the first time 3-D printing has been used to treat tracheobronchomalacia—at least in a human.
In a first-of-its-kind operation in the United States, a team of doctors at Duke University Hospital helped create a bioengineered blood vessel and transplanted it into the arm of a patient with end-stage kidney disease. The procedure was the first U.S. clinical trial to test the safety and effectiveness of the bioengineered blood vein.
In seventh grade, now 25-year-old Nikolai Begg, 2013 Lemelson-MIT Student Prize winner, was assigned a general project for English class where he had to pick a topic and write a report. That year, in life science class he took a great interest in this field, choosing to write his report on surgical robots. Able to interview surgeons using surgical robots and engineers designing them, Begg discovered an incredible field.
In a medical first, doctors used plastic particles and a 3D laser printer to create an airway splint to save the life of a baby boy who used to stop breathing nearly every day. Because of a birth defect, the Kaiba Gionfriddo’s airway kept collapsing, causing his breathing to stop and often his heart, too. Doctors in Michigan had been researching artificial airway splints but had not implanted one in a patient yet.
Scientists at Princeton University used off-the-shelf printing tools to create a functional ear that can "hear" radio frequencies far beyond the range of normal human capability. Standard tissue engineering involves seeding types of cells onto a scaffold of a polymer material called a hydrogel. But this method is not useful for complex 3D shapes, which is why researchers turned to 3D printing methods.
The biggest thing in operating rooms these days is a million-dollar, multi-armed robot named da Vinci, used in nearly 400,000 surgeries in America last year. But now the high-tech helper is under scrutiny over reports of problems, including several deaths that may be linked with it, and the high cost of using the robotic system. Is it time to curb the robot enthusiasm?
The NeuroBlate Thermal Therapy System is a new device that uses a minimally invasive, magnetic resonance imaging (MRI)-guided laser system to coagulate, or heat and kill, brain tumors. The MRI basically "cooks" brain tumors in a controlled fashion to destroy them. The first-in-human study of the system finds that it appears to provide a new, safe and minimally invasive procedure for treating recurrent glioblastoma, a malignant type of brain tumor.
Although bladder cancer is the sixth most common form of cancer in the U.S. and the most expensive to treat, the basic method that doctors use to treat it hasn’t changed much in more than 70 years. A research team may soon be changing that dramatically after having developed a prototype telerobotic platform designed to be inserted through natural orifices—in this case the urethra—that can provide surgeons with a much better view, making it easier to remove tumors.
Heart care is in the midst of a transformation. Many problems that once required sawing through the breastbone and opening up the chest for open heart surgery now can be treated with a nip, twist, or patch through a tube. These minimal procedures used to be done just to unclog arteries and correct less common heart rhythm problems. Now some patients are getting such repairs for valves, irregular heartbeats, holes in the heart and other defects—without major surgery.
An RTI International-developed prototype catheter that can generate live, streaming 3D ultrasound images from inside the heart has recently received a Cardiovascular Innovation Award at the 2013 Cardiovascular Research Technologies Annual Symposium. Called a live volumetric imaging intracardiac catheter, the technology has the potential to improve catheter-based heart procedures.
The future is unclear for a promising heart device aimed at preventing strokes in people at high risk of them because of an irregular heartbeat. Early results from a key study of Boston Scientific Corp.'s Watchman device suggested it is safer than previous testing found, but may not be better than a drug that is used now for preventing strokes, heart-related deaths and blood clots in people with atrial fibrillation over the long term.
Working with patients with electrodes implanted in their brains, researchers in California and Texas have shown for the first time that areas of the brain work together at the same time to recall memories. The unique approach promises new insights into how we remember details of time and place.
Drawing upon nature for inspiration, a team of researchers has created a new artificial lens that is nearly identical to the natural lens of the human eye. Made up of thousands of nanoscale polymer layers, the lens may one day provide more natural performance in implantable lenses. It also may lead to superior ground and aerial surveillance technology.
In recent years, researchers working to enhance transdermal drug delivery have focused on low-frequency ultrasound, because the high-frequency waves don’t have enough energy. However, these systems usually produce abrasions in the treated area. In a new study, engineers have combined high and low frequencies to enhance the permeability of skin to drugs, making transdermal drug delivery more efficient.
Needle injections are among the least popular staples of medical care. A new laser-based system, however, that blasts microscopic jets of drugs into the skin could soon make getting a shot as painless as being hit with a puff of air. The system uses an erbium-doped yttrium aluminum garnet laser to propel a tiny, precise stream of medicine with just the right amount of force.
To cut down on postoperative problems, particularly those involving abdomenal surgery, Johns Hopkins undergraduates have invented a disposable suturing tool to guide the placement of stitches and guard against the accidental puncture of internal organs. Called FastStitch, it’s described a cross between a pliers and a hole-puncher.
A international research team has mimicked and recreated the intricate properties of human fingertips using semiconductor devices. The devices, shown to be capable of responding with high precision to the stresses and strains associated with touch and finger movement, may lead to the development of advanced surgical gloves.
Microscopically small submarines that can swim through our blood to clear out clogged arteries or destroy malignant tumors. Various micro- and nanomachines have already been developed, but a new type of machine introduced by American researchers finally has enough propulsive power to penetrate tissue and overcome cellular barriers.
Government health experts said Thursday there are few reasons to continue using metal-on-metal hip implants, amid growing evidence that the devices can break down early and expose patients to dangerous metallic particles. The devices were originally marketed as a longer-lasting alternative to older ceramic and plastic models. But recent data from the U.K. and other foreign countries suggests they are more likely to deteriorate.
The best doctors strive to relieve their patients' burdens. A physician in Houston asked Rice University students to help him do so in the most literal way. A team of bioengineering seniors built a prototype device to literally lift the weight from obese patients who, while undergoing surgical procedures, might otherwise have trouble breathing.
Frustrated by the flimsy, disposable construction of typical trauma shears, Scott Forman, an emergency room physician, teamed up with Sandia National Laboratories engineer Mark Reece to design a better tool. The result is a shear that handle tough materials like Kevlar without having to be thrown away afterward. And it has a few other cool features as well.
Cochlear implants have restored basic hearing to some 220,000 deaf people, but the microphone and electronics can be cumbersome and can prevent them from participating in certain activities like swimming. Engineers have designed a tiny prototype microphone that can be implanted in the middle ear, and its form factor has been tested on cadavers. Tests on live humans are still a few years away.
The mitotic spindle is an apparatus that segregates chromosomes during cell division. But following some nanosurgery conducted by Harvard University, its structure may be more complex than the standard textbook picture suggests. Using a femtosecond laser, researchers have shown the true structure of its protein strands.