When it comes to communicating with each other, some cells may be more "old school" than was previously thought. Certain types of stem cells use microscopic, thread-like nanotubes to communicate with neighboring cells, like a landline phone connection, rather than sending a broadcast signal, researchers have discovered.
A team of researchers has created a new implantable drug-delivery system using nanowires that...
Researchers have found an easy way to produce carbon nanoparticles that are small enough to...
Heat may be the key to killing certain types of cancer, and new research from a team including...
Someday, treating patients with nanorobots could become standard practice to deliver medicine specifically to parts of the body affected by disease. But merely injecting drug-loaded nanoparticles might not always be enough to get them where they need to go. Now scientists are reporting in Nano Letters the development of new nanoswimmers that can move easily through body fluids to their targets.
Many cancer patients survive treatment only to have a recurrence within a few years. Recurrences and tumor spreading are likely due to cancer stem cells that can be tough to kill with conventional cancer drugs. But now researchers have designed nanoparticles that specifically target these hardy cells to deliver a drug. The nanoparticle treatment, reported in ACS Nano, worked far better than the drug alone in mice.
Researchers have developed an ultracompact highly sensitive nanomechanical sensor for analyzing the chemical composition of substances and detecting biological objects, such as viral disease markers, which appear when the immune system responds to incurable or hard-to-cure diseases, including HIV, hepatitis, herpes, and many others. The sensor will enable doctors to identify tumor markers.
Nanoengineers at the Univ. of California, San Diego developed a gel filled with toxin-absorbing nanosponges that could lead to an effective treatment for skin and wound infections caused by MRSA, an antibiotic-resistant bacteria. This "nanosponge-hydrogel" minimized the growth of skin lesions on mice infected with MRSA, without the use of antibiotics.
The printer looks like a toaster oven with the front and sides removed. Its metal frame is built up around a stainless steel circle lit by an ultraviolet light. Stainless steel hydraulics and thin black tubes line the back edge, which lead to an inner, topside box made of red plastic. All together, the gray metal frame is small enough to fit on top of an old-fashioned school desk, but nothing about this 3D printer is old school.
Imagine taking strands of DNA and using it to build tiny structures that can deliver drugs to targets within the body or take electronic miniaturization to a whole new level. While it may still sound like science fiction to most of us, researchers have been piecing together and experimenting with DNA structures for decades.
Water, when cooled below 32 F, eventually freezes. But some substances, when they undergo a process called "rapid-freezing" or "supercooling," remain in liquid form. The supercooling phenomenon has been studied for its possible applications in a wide spectrum of fields. A new Tel Aviv Univ. study published in Scientific Reports is the first to break down the rules governing the complex process of crystallization through rapid-cooling.
As baby boomers age, the number of people diagnosed with Parkinson's disease is expected to increase. Patients who develop this disease usually start experiencing symptoms around age 60 or older. Currently, there's no cure, but scientists are reporting a novel approach that reversed Parkinson's-like symptoms in rats. Their results, published in ACS Nano, could one day lead to a new therapy for human patients.
Fastening protein-based medical treatments to nanoparticles isn't easy. With arduous chemistry, scientists can do it. But like a doomed marriage, the fragile binding that holds them together often separates. This problem, which has limited how doctors can use proteins to treat serious disease, may soon change.
Researchers have demonstrated a promising new way to increase the effectiveness of radiation in killing cancer cells. The approach involves gold nanoparticles tethered to acid-seeking compounds called pHLIPs. The pHLIPs (pH low-insertion peptides) home in on high acidity of malignant cells, delivering their nanoparticle passengers straight to the cells’ doorsteps.
A new device developed by Univ. of California, Los Angeles, engineers and doctors may eventually help scientists study the development of disease, enable them to capture improved images of the inside of cells and lead to other improvements in medical and biological research.
Therapeutic agents intended to reduce dental plaque and prevent tooth decay are often removed by saliva and the act of swallowing before they can take effect. But a team of researchers has developed a way to keep the drugs from being washed away. Dental plaque is made up of bacteria enmeshed in a sticky matrix of polymers, a polymeric matrix, that is firmly attached to teeth.
Scientists have developed tiny nanoneedles that have successfully prompted parts of the body to generate new blood vessels, in a trial in mice. The researchers, from Imperial College London and Houston Methodist Research Institute, hope their nanoneedle technique could ultimately help damaged organs and nerves to repair themselves and help transplanted organs to thrive.
Carbon nanotube fibers invented at Rice Univ. may provide a way to communicate directly with the brain. The fibers have proven superior to metal electrodes for deep brain stimulation and to read signals from a neuronal network. Because they provide a two-way connection, they show promise for treating patients with neurological disorders while monitoring the real-time response of neural circuits in areas that control movement and mood.
Acne, a scourge of adolescence, may be about to meet its ultra-high-tech match. By using a combination of ultrasound, gold-covered particles and lasers, researchers from Univ. of California, Santa Barbara and Sebacia have developed a targeted therapy that could potentially lessen the frequency and intensity of breakouts, relieving acne sufferers the discomfort and stress of dealing with severe and recurring pimples.
Materials resulting from chemical bonding of glucosamine, a type of sugar, with fullerenes, kind of nanoparticles known as buckyballs, might help to reduce cell damage and inflammation occurring after stroke. A team from the Max Planck Institute in Germany has tested this on mice, opening the door to potential new drugs for the cerebrovascular accident.
Researchers at Massachusetts Institute of Technology have developed a method to stimulate brain tissue using external magnetic fields and injected magnetic nanoparticles: a technique allowing direct stimulation of neurons, which could be an effective treatment for a variety of neurological diseases, without the need for implants or external connections.
A research team from The Scripps Research Institute (TSRI), Mayo Clinic and other institutions has identified a new class of drugs that in animal models dramatically slows the aging process—alleviating symptoms of frailty, improving cardiac function and extending a healthy lifespan.
Animal study shows that a nanoparticle applied at the time of surgery slowly releases needed medicine to reduce risk of rejection after eye surgery.
Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by Massachusetts Institute of Technology researchers can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy attack against the disarmed tumors.
Univ. of Manchester scientists have used graphene to target and neutralize cancer stem cells while not harming other cells. This new development opens up the possibility of preventing or treating a broad range of cancers, using a non-toxic material.
Researchers at McGill Univ. have developed a new, low-cost method to build DNA nanotubes block-by-block, a breakthrough that could help pave the way for scaffolds made from DNA strands to be used in applications such as optical and electronic devices or smart drug delivery systems. Many researchers, including the McGill team, have previously constructed nanotubes using a method that relies on spontaneous assembly of DNA in solution.
Chemical engineers have designed a new type of self-healing hydrogel that could be injected through a syringe. Such gels, which can carry one or two drugs at a time, could be useful for treating cancer, macular degeneration, or heart disease, among other diseases, the researchers say.
With a low price tag and mild flavor, tilapia has become a staple dinnertime fish for many Americans. Now it could have another use: helping to heal our wounds. In ACS Applied Materials & Interfaces, scientists have shown that a protein found in this fish can promote skin repair in rats without an immune reaction, suggesting possible future use for human patients.
Scientists have shown that gold nanotubes have many applications in fighting cancer: internal nanoprobes for high-resolution imaging, drug delivery vehicles and agents for destroying cancer cells. The study, published in Advanced Functional Materials, details the first successful demonstration of the biomedical use of gold nanotubes in a mouse model of human cancer.
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