Scientists in Missouri have successfully created nanoparticles made of a radioactive form of the element lutetium. By covering these particles with gold shells and attaching targeting agents, they have a tool that can seek out dangerous secondary lymphoma tumors. They recently demonstrated the nanoparticles can find the tumors without attaching to or damaging healthy cells.
Columbia University has signed a licensing agreement with Varian Medical Systems for new imaging software that facilitates 3D segmentation, the process by which anatomical structures in medical images are distinguished from one another—an important step in the precise planning of cancer surgery and radiation treatments.
Over the past few decades, scientists have developed many devices that can reopen clogged arteries, including angioplasty balloons and metallic stents. While generally effective, each of these treatments has drawbacks, including the risk of side effects. A new study analyzes the potential usefulness of a new treatment that combines the benefits of angioplasty balloons and drug-releasing stents, but may pose fewer risks.
Researchers at Columbia University and Stanford University have developed a computational method that enables scientists to visualize and interpret "high-dimensional" data produced by single-cell measurement technologies such as mass cytometry. A sophisticated algorithm converts difficult-to-interpret data into visual representations similar to two-dimensional "scatter plots".
The University of Chicago has recently launched the first secure cloud-based computing system that enables researchers to access and analyze human genomic cancer information, such as the The Cancer Genome Atlas, without the costly and cumbersome infrastructure normally needed to download and store massive amounts of data.
Scientists have finally recovered stem cells from cloned human embryos, a longstanding goal that could lead to new treatments for such illnesses as Parkinson's disease and diabetes. A prominent expert called the work a landmark, but noted that a different, simpler technique now under development may prove more useful.
Engineers combine layers of flexible materials into pressure sensors to create a wearable heart monitor thinner than a dollar bill. The skin-like device could one day provide doctors with a safer way to check the condition of a patient's heart.
It’s a familiar scenario—a patient receives a medical implant and days later, the body attacks the artificial valve or device, causing complications to an already compromised system. Expensive medical devices and surgeries often are thwarted by the body’s natural response to attack something in the tissue that appears foreign. Now, University of Washington engineers have demonstrated in mice a way to prevent this sort of response.
Rice University students have created a way to help health care workers track vaccines and keep them at a safe temperature. The SAFE Vaccine senior engineering design team assembled a device to regulate the temperature of any standard refrigerator to keep it within a range that’s safe for vaccines. Their invention also tracks vaccine stock, usage, and expiration dates and, as a result, takes a load of paperwork off the backs of nurses.
When Michael Gore stands, it's a triumph of science and engineering. Eleven years ago, Michael Gore was paralyzed from the waist down in a workplace accident, yet he rises from his wheelchair to his full 6-foot-2-inches and walks across the room with help from a lightweight wearable robot. Still at least a year away from the market, the 27-pound Indego is the lightest of the powered exoskeletons that are now appearing in greater numbers.
When Michael Gore stands, it's a triumph of science and engineering. Eleven years ago, Gore was paralyzed from the waist down in a workplace accident, yet he rises from his wheelchair and walks across the room with help from a lightweight wearable robot.
Take a swab of saliva from your mouth and within minutes your DNA could be ready for analysis and genome sequencing with the help of a new device. University of Washington engineers and NanoFacture, a Bellevue, Wash., company, have created a device that can extract human DNA from fluid samples in a simpler, more efficient, and environmentally friendly way than conventional methods.
Duke University biomedical engineers have grown three-dimensional human heart muscle that acts just like natural tissue. The "heart patch" grown in the laboratory from human cells overcomes two major obstacles facing cell-based therapies—the patch conducts electricity at about the same speed as natural heart cells and it "squeezes" appropriately.
Medtronic has put two new implantable heart devices on the market after receiving approval from federal regulators. The FDrA approved the sale of the Viva heart resynchronization devices and Evera implantable cardioverter defibrillators. Cardiac resynchronization therapy devices are used to treat heart failure and implantable defibrillators are used to treat rapid heartbeats.
Scientists at Princeton University used off-the-shelf printing tools to create a functional ear that can "hear" radio frequencies far beyond the range of normal human capability. Standard tissue engineering involves seeding types of cells onto a scaffold of a polymer material called a hydrogel. But this method is not useful for complex 3D shapes, which is why researchers turned to 3D printing methods.
Researchers at the Synthetic Biology Project at the Woodrow Wilson International Center for Scholars have recently reported that the number of private and public entities conducting research in synthetic biology worldwide grew significantly between 2009 and 2013. Their findings, which include more than 500 organizations, are tracked on an interactive online map.
In 2012, more than 3 million people had stents inserted in their coronary arteries. But the longer a stent is in the body, the greater the risk of late-stage side effects. Studies have investigated iron- and magnesium-based bioabsorbable stents, but iron rusts and magnesium dissolves too fast. Recent research shows that a certain type of zinc alloy might be the answer.
Hannah Warren has been unable to breathe, eat, drink or swallow on her own since she was born in South Korea in 2010. Until the operation at a central Illinois hospital, she had spent her entire life in a hospital in Seoul. Now, the 2-year-old girl born without a windpipe now has a new one grown from her own stem cells, the youngest patient in the world to benefit from the experimental treatment.
Computer simulations conducted in Germany have shown that the reduction of natural dental wear might be the main cause for widely spread non-carius cervical lesions—the loss of enamel and dentine at the base of the crown—in our teeth. The discovery was made by examining the biomechanical behavior of teeth using finite element analysis methods typically applied to engineering problems.
They sweep. They swab. They sterilize. And still the germs persist. In U.S. hospitals, an estimated 1 in 20 patients pick up infections they didn't have when they arrived. This causes hospitals to try all sorts of new approaches to stop their spread, including machines that resemble "Star Wars" robots and emit ultraviolet light or hydrogen peroxide vapors.
Coating medical supplies with an antimicrobial material is one approach that bioengineers are using to combat the increasing spread of multidrug-resistant bacteria. A research team in Singapore has now developed a highly effective antimicrobial coating based on cationic polymers. The coating can be applied to medical equipment, such as catheters.
To understand the development of sensory representations within our brain, we have to comprehend how electrical activation is linked to the sensory experience. For this reason, researchers in Italy have analyzed the behavior and the activation of neural networks in rats while carrying out tactile object recognition tests. The study represents the first time that the activity of multiple neurons has been monitored.
Scientists at the University of California, Berkeley, have discovered that when we embark on a targeted search, various visual and non-visual regions of the brain mobilize to track down a person, animal, or thing. That means that if we're looking for a youngster lost in a crowd, the brain areas usually dedicated to recognizing other objects shift their focus and join the search party.
How do nerve cells—which can each be up to three feet long in humans—keep from rupturing or falling apart? Recent research reports that axons, the long, cable-like projections on neurons, are made stronger by a unique modification of the common molecular building block of the cell skeleton. The finding may help guide the search for treatments for neurodegenerative diseases.
Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a new tool to help surgeons use X-rays to track devices used in “minimally invasive” surgical procedures while also limiting the patient’s exposure to radiation from the X-rays.