Medicare may soon begin paying for yearly scans to detect lung cancer in certain current or former heavy smokers. The Centers for Medicare and Medicaid Services on Monday issued a long-awaited proposal to begin covering the screening for high-risk beneficiaries if their doctors agree they meet the criteria.
Univ. of Virginia biomedical engineers are building an entire technology around tiny, microscopic bubbles– a technology that has the potential to play an important role in diagnosing as well as treating disease like stroke and cancer.
A diet rich in fruit and vegetables is linked to a variety of improved health outcomes, but accurately measuring consumption by self-report, especially with children, is challenging and can be of questionable validity. But a device being developed in a collaboration that involves researchers from the Yale School of Public Health has the potential to change that.
Researchers are close to commercializing a new type of medical imaging technology that could diagnose cardiovascular disease by measuring ultrasound signals from molecules exposed to a fast-pulsing laser. The system takes precise 3-D images of plaques lining arteries and identifies deposits that are likely to rupture and cause heart attacks.
A new technology that may assist in the treatment of brain cancer and other neurological diseases is the subject of an article in Technology. According to the authors, the current medical use of chemotherapy to treat brain cancer can be inefficient because of the blood-brain-barrier that impedes the delivery of drugs out of blood vessels and into the tumor.
The process of cell division is central to life. The last stage, cytokinesis, when two daughter cells split from each other, has fascinated scientists but has been notoriously difficult to study. Now Harvard Medical School systems biologists report that they have reconstituted cytokinesis, complete with signals that direct molecular traffic, without the cell.
Stanford Univ. School of Medicine researchers have developed a new formula for delivering the therapeutic peptide apelin to heart tissue for treatment of hypertrophy, a hereditary disease commonly attributed to sudden death in athletes. The nanoscale delivery system, which dramatically increases the peptide’s stability, shows promise for treating heart disease in humans, the researchers said.
Cartilage, for example, is a hard material that caps the ends of bones and allows joints to work smoothly, but engineered replacement tissue is, mechanically, far from native tissue. Researchers in California report the use of an enzyme that has greatly improved engineering cartilage built from cultures. It promotes cross-linking and makes the material stronger.
The heart holds its own pool of immune cells capable of helping it heal after injury, according to new research in mice at Washington University School of Medicine in St. Louis. When the heart is injured, beneficial immune cells are often supplanted by bone marrow cells, which cause damaging inflammation. In a mouse model, researchers showed that blocking the bone marrow’s macrophages protects the organ’s beneficial pool of macrophages.
The condition of an athlete's heart has for the first time been accurately monitored throughout the duration of a marathon race. The real-time monitoring was achieved by continuous electrocardiogram (ECG) surveillance and data transfer over a public mobile phone network. The new development allows instantaneous diagnosis of potentially fatal rhythm disorders.
A team led by Virginia Tech researchers studied cells found in breast and other types of connective tissue and discovered new information about cell transitions that take place during wound healing and cancer. They developed mathematical models to predict the dynamics of cell transitions, and by comparison gained new understanding of how a substance known as transforming growth factor triggers cell transformations.
Cancer researchers have found that a simple blood test might help diagnose pancreatic cancer, one of the most deadly forms of the disease. In new research at Indiana Univ., scientists have found that several microRNAs, which are small RNA molecules, circulate at high levels in the blood of pancreatic cancer patients.
Houston Methodist Research Institute scientists will receive about $1.25 million from the Center for the Advancement of Science in Space to develop an implantable, nanochannel device that delivers therapeutic drugs at a rate guided by remote control. The device's effectiveness will be tested aboard the International Space Station and on Earth's surface.
In many areas of the developing world, there’s limited access to electricity, and many places have never had any type of power infrastructure. This presents a challenge for aid workers and doctors. In the recent past, vaccines that needed to be stored at cold, relatively constant temperatures couldn’t be taken into the remote areas where they were needed most.
New achievements in synthetic biology, which will allow complex cellular recognition reactions to proceed outside of living cells, will dare scientists to dream big: There could one day be inexpensive, shippable and accurate test kits that use saliva or a drop of blood to identify specific disease or infection.
A group of scientists in Florida have combined medicine and advanced nanotechnological engineering to create a smarter, more targeted therapy that could overcome the most lethal gynecologic cancer. The technology involves combining Taxol, a chemotherapy drug, with magneto-electric nanoparticles that can penetrate the blood-brain barrier.
Bio-engineers are working on the development of biological computers: biological material that can be integrated into cells to change their functions. Researchers in Europe have now developed a biological circuit that controls the activity of individual sensor components using internal "timer". This circuit prevents a sensor from being active when not required by the system; when required, it can be activated via a control signal.
Developing invisible implantable medical sensor arrays, a team of Univ. of Wisconsin-Madison engineers has overcome a major technological hurdle in researchers’ efforts to understand the brain. The team described its technology, which has applications in fields ranging from neuroscience to cardiac care and even contact lenses, in Nature Communications.
While megakaryocytes are best known for producing platelets that heal wounds, these "mega" cells found in bone marrow also play a critical role in regulating stem cells according to new research from the Stowers Institute for Medical Research. The study is the first to show that hematopoietic stem cells (the parent cells) can be directly controlled by their own progeny (megakaryocytes).
Scientists perform genome sequences because want to know why individuals differ from each other and how these differences are encoded in the DNA. However, sequencing a complete genome still costs around $1,000, and sequencing hundreds of individuals would be costly. In two recent review papers, scientists discuss why DNA sequencing of entire groups, or pool sequencing, can be an efficient and cost-effective approach.
Medical researchers would like to plant tiny electronic devices deep inside our bodies to monitor biological processes and deliver pinpoint therapies to treat illness or relieve pain. But so far engineers have been unable to make such devices small and useful enough. Providing electric power to medical implants has been one stumbling block. Using wires or batteries to deliver power tends to make implants too big, too clumsy—or both.
A leader in the field of minimally invasive surgery device development operates state-of-the-art R&D and manufacturing facilities—facilities that depend on today’s most advanced quality assurance/quality testing procedures. To ensure all equipment leaving its production facilities meets the highest performance and reliability standards, the company relies on a QA/QC system made possible by industrial microscope and analyzer solutions.
The millions of people worldwide who suffer from the painful bladder disease known as interstitial cystitis (IC) may soon have a better, long-term treatment option, thanks to a controlled-release, implantable device invented by Massachusetts Institute of Technology Prof. Michael Cima and other researchers. The device is a pretzel-shaped silicone tube that could be inserted into the bladder, slowly releasing lidocaine over two weeks.
Researchers at The Scripps Research Institute have created a synthetic molecule that mimics “good” cholesterol and have shown it can reduce plaque buildup in the arteries of animal models. The molecule, taken orally, improved cholesterol in just two weeks.
New research involving scientists in the U.S. and Israel offers new insight into the lethal interaction between cancer cells and the immune system's communications network. The study authors devised a new computer program that models a specific channel of cell-to-cell communication involving exosomes that both cancer and immune cells harness to communicate with other cells. This “cyberwarfare” model reveals three distinct states of cancer.