Tamoxifen is an oral drug that is used for breast cancer prevention and as therapy for non-invasive breast cancer and invasive cancer. Seema Khan, a professor of surgery at Northwestern Univ., has found that is tamoxifen is used in gel form, it reduces the growth of cancer cells while minimizing dangerous side effects such as blood clots and uterine cancer.
A microbe detection array technology developed by Lawrence Livermore National Laboratory (LLNL) scientists could provide a new rapid method for public health authorities to conduct surveillance for emerging viral diseases. This possible use of the Lawrence Livermore Microbial Detection Array (LLMDA) was studied by an international team of researchers from eight nations in a paper published in the PLOS ONE.
The creators of a unique kit containing 3-D printed anatomical body parts say it will revolutionize medical education and training, especially in countries where cadaver use is problematic. The “3D Printed Anatomy Series”, developed by experts in Australia, is thought to be the first commercially available resource of its kind. The kit contains no human tissue, yet it provides all the major parts of the body required to teach anatomy.
A cheap, portable, microchip-based test for diagnosing type-1 diabetes could speed up diagnosis and enable studies of how the disease develops. Handheld microchips distinguish between the two main forms of diabetes mellitus, which are both characterized by high blood-sugar levels but have different causes. Until now, making the distinction has required a slow, expensive test available only in sophisticated healthcare settings.
According to recent research in the U.K. , use of electronic health records to understand the best available treatment for patients, from a range of possible options, is more efficient and less costly for taxpayers than the existing clinical trial process.
The most advanced vaccine for dengue only offers modest protection but could still help millions of people avoid the devastating effects of the disease known as "breakbone fever," according to a large trial. There's no treatment for dengue, which causes symptoms including fever, joint pain, headaches and bleeding. About half the world's population is at risk from the mosquito-borne disease, which sickens about 100 million people every year.
The changing dynamic of health studies driven by “big data” research projects will empower patients to become active participants who provide real-time information such as symptoms, side effects and clinical outcomes, according to researchers at Duke Medicine. The analysislays out a new paradigm for health research, particularly comparative effectiveness studies that are designed to assess which therapies work best in clinical practice.
Scientists at the Massachusetts Institute of Technology are developing an audio reading device to be worn on the index finger of people whose vision is impaired, giving them affordable and immediate access to printed words. The so-called FingerReader, a prototype produced by a 3-D printer, fits like a ring on the user's finger, and is equipped with a small camera that scans text.
According to a team of researchers who applied a statistical technique to conventional, coarse-scale climate models, population centers in cool, highland regions of East Africa could be more vulnerable to malaria than previously thought, while population centers in hot, lowland areas could be less vulnerable. The new approach improves the accuracy of earlier efforts that used global climate model simulations results.
Located deep in the human gut, the small intestine is not easy to examine: X-rays, MRIs and ultrasound images each suffer limitations. Univ. at Buffalo researchers are developing a new imaging technique involving nanoparticles suspended in liquid to form “nanojuice” that patients would drink. Upon reaching the small intestine, doctors would strike the nanoparticles with laser light, providing a non-invasive, real-time view of the organ.
Obtaining evidence of genetic changes to make a cancer diagnosis usually requires a biopsy, which can be problematic for sensitive regions of the body such as the lungs. Based on recent review of patients with lung cancer, researchers have found that scanning the tumor cells with quantitative computed tomography based texture analysis (QTA) determines (with 90% accuracy) whether the patient's tumor had a cancer-causing gene mutation.
In a basement laboratory at Fort Sam Houston military base in Texas, a research team has spent the last two years simulating improvised explosive device blasts on postmortem pig eyes using a high-powered shock tube. Their most striking discovery is that these blasts can damage the optic nerve, and these injuries can occur even at low pressures, causing visual defects that until now have been associated traumatic brain injuries.
Optogenetics relies on light-sensitive proteins that can suppress or stimulate electrical signals within cells. This technique requires a light source to be implanted in the brain, where it can reach the cells to be controlled. Massachusetts Institute of Technology engineers have now developed the first light-sensitive molecule that enables neurons to be silenced noninvasively, using a light source outside the skull.
For the first time, neuroscientists have shown they can control muscle movement by applying optogenetics, a technique that allows scientists to control neurons’ electrical impulses with light, to the spinal cords of animals that are awake and alert. Previously, scientists have used electrical stimulation or pharmacological intervention to control neurons’ activity, but these approaches were not precise enough.
Imagine a low-cost treatment for a life-threatening infection that could cure up to 90% of patients with minimal side effects, often in a few days.It may sound like a miracle drug, but this cutting-edge treatment is profoundly simple—though somewhat icky: take the stool of healthy patients to cure those with hard-to-treat intestinal infections.
A team of scientists in Japan and New Zealand have combined lasers, nanotechnology, and neuroscience to develop a new, versatile drug delivery system. The precise timing of a femtosecond laser is used to release dopamine, a neurochemical, that is dysfunctional in Parkinson’s Disease in a controlled and repeatable manner that mimics the natural dynamic release mechanism.
3-D mammograms may be better at finding cancer than regular scans, a large study suggests, although whether that means saving more lives isn't known. The study involved almost half a million breast scans, with more than one-third of them using relatively new 3-D imaging along with conventional scans. The rest used regular mammograms alone.
Researchers compare the processing of biological fluid samples with searching for a needle in a haystack—only in this case, the haystack could be diagnostic samples, and the needle might be tumor cells present in just ppm concentrations. Now, a new way of processing these samples could make such detections possible in real time.
Trillions of bacteria live in and on the human body; a few species can make us sick, but many others keep us healthy by boosting digestion and preventing inflammation. Although there's plenty of evidence that these microbes play a collective role in human health, we still know very little about most of the individual bacterial species that make up these communities.
Women with heart failure are less likely to get a special kind of pacemaker than men, but more likely to benefit from the device, a government analysis suggests. The findings come from the first study of its kind conducted by researchers at the U.S. Food and Drug Administration.
Lung cancer causes more deaths in the U.S. than the next three most common cancers combined, and the main reason is poor detection methods. A new device developed by a team of Israeli, American and British cancer researchers may turn the tide by both accurately detecting lung cancer and identifying its stage of progression. The breathalyzer test is embedded with a "NaNose" nanotech chip to literally "sniff out" cancer tumors.
A biological detection technology developed by Lawrence Livermore National Laboratory scientists can detect bacterial pathogens in the wounds of U.S. soldiers that have previously been missed by other technologies. This advance may, in time, allow an improvement in how soldiers' wounds are treated.
Researchers have shown how to modify a smartphone so that it can be used to measure a person's walking gait to prevent falls in people with compromised balance, such as the elderly or those with Parkinson's disease. The innovation, being commercialized as SmartGait, is designed as a tool to aid health care officials in assessing a person's risk of falling and identifying ways to avoid injury.
After a large stroke, motor skills barely improve, even with rehabilitation. An experiment conducted on rats demonstrates that a course of therapy combining the stimulation of nerve fiber growth with drugs and motor training can be successful. The key, however, is the correct sequence: Paralyzed animals only make an almost complete recovery if the training is delayed until after the growth promoting drugs have been administered.
Your eye could someday house its own high-tech information center, tracking important changes and letting you know when it’s time to see an eye doctor. Univ. of Washington engineers have designed a low-power sensor that could be placed permanently in a person’s eye to track hard-to-measure changes in eye pressure.