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The Lead

A new way to diagnose malaria

September 2, 2014 7:38 am | by Anne Trafton, MIT News Office | News | Comments

Over the past several decades, malaria diagnosis has changed very little. After taking a blood sample from a patient, a technician smears the blood across a glass slide, stains it with a special dye and looks under a microscope for the Plasmodium parasite, which causes the disease. This approach gives an accurate count of how many parasites are in the blood, but is not ideal because there is potential for human error.

From nose to knee: Engineered cartilage regenerates joints

August 28, 2014 11:59 am | News | Comments

Cartilage lesions in joints often appear in older...

Smartphone app can detect newborn jaundice in minutes

August 27, 2014 11:40 am | by Michelle Ma, Univ. of Washington | News | Comments

Newborn jaundice: It’s one of the last things a parent wants to deal with, but it’s...

Breakthrough antibacterial approach could resolve serious skin infections

August 26, 2014 4:30 pm | by Nancy Ambrosiano, Los Alamos National Laboratory | News | Comments

Like a protective tent over a colony of harmful bacteria, biofilms make the treatment of skin...

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Do-it-yourself blood pressure care can beat MDs

August 26, 2014 4:26 pm | by Lindsey Tanner - AP Medical Writer - Associated Press | News | Comments

"Do-it-yourself" blood pressure measurements and medicine changes work better than usual doctor-office care in some patients, a study of older adults in England found. Those who did their own readings at home and adjusted their medicine as needed had healthier blood pressure levels after a year than those who got standard doctors' care.

Eye implant could lead to better glaucoma treatments

August 26, 2014 8:21 am | by Bjorn Carey, Stanford News Service | News | Comments

For the 2.2 million Americans battling glaucoma, the main course of action for staving off blindness involves weekly visits to eye specialists who monitor increasing pressure within the eye. Now researchers have developed an eye implant that could help stave off blindness caused by glaucoma. The tiny eye implant developed at Stanford Univ. could enable patients to take more frequent readings from the comfort of home.

A glucose meter of a different color provides continuous monitoring

August 26, 2014 7:53 am | by Liz Ahlberg, Physical Sciences Editor, Univ. of Illinois, Urbana-Champaign | Videos | Comments

Univ. of Illinois engineers are bringing a touch of color to glucose monitoring. The researchers developed a new continuous glucose monitoring material that changes color as glucose levels fluctuate, and the wavelength shift is so precise that doctors and patients may be able to use it for automatic insulin dosing—something now possible using current point measurements like test strips.

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Sorting cells with sound waves

August 26, 2014 7:36 am | by Anne Trafton, MIT News Office | Videos | Comments

Researchers have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel. Their device, about the size of a dime, could be used to detect the extremely rare tumor cells that circulate in cancer patients’ blood, helping doctors predict whether a tumor is going to spread.

Living organ grown from lab-created cells

August 25, 2014 2:25 pm | Videos | Comments

Laboratory-grown replacement organs have moved a step closer with the completion of a new study. Scientists have grown a fully functional organ from transplanted laboratory-created cells in a living animal for the first time. They have created a thymus, an organ next to the heart that produces immune cells known as T cells that are vital for guarding against disease.

Future phones to use blood, speech to monitor HIV, stress, nutrition

August 25, 2014 9:30 am | by Cornell Univ. | News | Comments

David Erickson, a professor at Cornell Univ., will receive a $3 million National Science Foundation grant over five years to adapt smartphones for health monitoring. The program, dubbed PHeNoM for Public Health, Nanotechnology, and Mobility, aims to deploy three systems that can have an immediate impact on personal healthcare.

A surprising new role for natural killer T cells

August 25, 2014 9:25 am | News | Comments

In the past, immune cells were clearly divided into innate cells, which respond to attacks in a non-specific way, and adaptive cells, which learn to recognize new antigens and gain the ability to rapidly react to later attacks. Researchers at RIKEN in Japan have discovered that is not always the case, having found that killer T cells previously thought to be innate, and thus short-lived, can remain in the lung for up to nine months.

Gold Standard for Laparoscopic Surgery

August 22, 2014 2:38 pm | Award Winners

Laparoscopic Surgery was introduced with a goal to reduce morbidities associated with open surgical techniques. Twenty years later, although it has brought much better outcomes across a number of indicators, it still has some significant patient morbidities and mortality risks associated with it. Port site hernia is one such example. No ubiquitous global device-based standard of care developed has been accepted to deal with this issue. neoSurgical’s neoClose brings a simple, accurate technology/device-based solution that can be deployed in less than 30 sec.

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Laser device may end pin pricks for diabetics

August 22, 2014 8:07 am | by John Sullivan, Office of Engineering Communications, Princeton Univ. | News | Comments

Princeton Univ. researchers have developed a way to use a laser to measure people's blood sugar, and, with more work to shrink the laser system to a portable size, the technique could allow diabetics to check their condition without pricking themselves to draw blood.

Reducing the Pain

August 21, 2014 4:51 pm | Award Winners

Milliken and Company’s ASSIST Silver is a low-adherent antimicrobial dressing used primarily in burn care for the management of skin grafts. The dressing incorporates three primary features: Active Fluid Management (AFM) technology, an ionic silver antimicrobial and a low-adherent layer.

Saving Childrens’ Lives

August 21, 2014 4:18 pm | Award Winners

Globally, 22 million infants aren’t receiving basic vaccines and 1.5 million children will die each year from vaccine-preventable diseases before they reach age five. This challenge is further complicated by the fact that most vaccines must be refrigerated, and more than a billion people globally don’t have reliable access to electricity. Vaccination rates are lowest in remote and rural locations. As part of Intellectual Ventures’ Global Good program, Intellectual Venture Labs (IVL) approached Stratos Product Development for help in developing an insulated container to strengthen and extend vaccination services in developing countries.

Medical Tests for the Developing World

August 21, 2014 3:52 pm | Award Winners

Novilytic’s Noviplex Plasma Collection Card is a self-contained, blood-plasma sampling device used to volumetrically collect a plasma aliquot independent of whole blood application volumes. The Noviplex requires no power and circumvents requirements for venipuncture-phlebotomy training, needles, special vials and equipment, refrigeration and centrifugation normally associated with traditional plasma methods.

Researchers use 3-D printers to create custom medical implants

August 21, 2014 10:18 am | by Dave Guerin, Louisiana Tech Univ. | News | Comments

A team of researchers at Louisiana Tech Univ. has developed an innovative method for using affordable, consumer-grade 3-D printers and materials to fabricate custom medical implants that can contain antibacterial and chemotherapeutic compounds for targeted drug delivery.

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Could elastic bands monitor patients’ breathing?

August 20, 2014 11:39 am | News | Comments

Research published in ACS Nano identifies a new type of sensor that could monitor body movement and advance the future of global health care. Although body motion sensors already exist in different forms, they have not been widely used due to their complexity and cost of production.

Many patients don’t understand electronic lab results

August 20, 2014 10:48 am | by Laurel Thomas Gnagey, Univ. of Michigan | News | Comments

While it's becoming commonplace for patients to see the results of laboratory work electronically, a new Univ. of Michigan study suggests that many people may not be able to understand what those numbers mean. The research found that people with low comprehension of numerical concepts—or numeracy—and low literacy skills were less than half as likely to understand whether a result was inside or outside the reference ranges.

Microchip reveals how tumor cells transition to invasion

August 18, 2014 11:06 am | by Kevin Stacey, Brown Univ. | News | Comments

Using a microengineered device that acts as an obstacle course for cells, researchers have shed new light on a cellular metamorphosis thought to play a role in tumor cell invasion throughout the body. The epithelial-mesenchymal transition (EMT) is a process in which epithelial cells, which tend to stick together within a tissue, change into mesenchymal cells, which can disperse and migrate individually.

New way to treat solid tumors

August 15, 2014 11:12 am | News | Comments

An international team of scientists has shown that an antibody against the protein EphA3, found in the micro-environment of solid cancers, has anti-tumor effects. As EphA3 is present in normal organs only during embryonic development but is expressed in blood cancers and in solid tumors, this antibody-based approach may be a suitable candidate treatment for solid tumors.

Non-invasive method controls size of molecules passing blood-brain barrier

August 14, 2014 4:38 pm | News | Comments

A new technique has demonstrated for the first time that the size of molecules penetrating the blood-brain barrier can be controlled using acoustic pressure. The innovative ultrasound approach uses acoustic pressure to let molecules through, and may help treatment for central nervous system diseases like Parkinson’s and Alzheimer’s.

Nanotech invention improves effectiveness of the “penicillin of cancer”

August 14, 2014 8:01 am | by Jared Sagoff, Argonne National Laboratory | News | Comments

By combining magnetic nanoparticles with one of the most common and effective chemotherapy drugs, Argonne National Laboratory researchers have created a way to deliver anti-cancer drugs directly into the nucleus of cancer cells. They have created nano-sized bubbles, or “micelles,” that contain magnetic nanoparticles of iron oxide and cisplatin, a conventional chemotherapy drug also known as “the penicillin of cancer.”

New material could enhance fast, accurate DNA sequencing

August 14, 2014 7:41 am | by Liz Ahlberg, Physical Sciences Editor, Univ. of Illinois, Urbana-Champaign | News | Comments

Gene-based personalized medicine has many possibilities for diagnosis and targeted therapy, but one big bottleneck: the expensive and time-consuming DNA sequencing process. Now, researchers at the Univ. of Illinois at Urbana-Champaign have found that nanopores in the material molybdenum disulfide (MoS2) could sequence DNA more accurately, quickly and inexpensively than anything yet available.

Tattoo biobatteries produce power from sweat

August 13, 2014 12:45 pm | Videos | Comments

In the future, working up a sweat by exercising may not only be good for your health, but it could also power your small electronic devices. Researchers report that they have designed a sensor in the form of a temporary tattoo that can both monitor a person’s progress during exercise and produce power from their perspiration.

A Potential New Route to Stopping Surgical Bleeding

August 13, 2014 10:44 am | by Lindsay Hock, Managing Editor | Articles | Comments

Surgical and trauma patients are at significant risk for morbidity and mortality from bleeding and/or leaking bodily fluids. With the number and complexity of surgeries rising, so is the need for better hemostatic agents to stop bleeding as quickly as possible. The history of approaches to hemostasis goes back to when people simply used their hands or a tool to apply to a wound to stop bleeding.

3-D Printing for Blood Recycling, Medical Developments

August 13, 2014 10:15 am | by Lindsay Hock, Managing Editor | Stratasys, Ltd. | Articles | Comments

Imagine your religious beliefs lied between you and your life. This is what happened in mid-April to Julie Penoyer, a 50-year-old U.K. heart patient and Jahovah’s Witness. Following her religious beliefs, her request when undergoing open-heart surgery was to not receive donated blood products.

“Shape-shifting” material could help reconstruct faces

August 13, 2014 8:49 am | News | Comments

Injuries, birth defects (such as cleft palates) or surgery to remove a tumor can create gaps in bone that are too large to heal naturally. And when they occur in the head, face or jaw, these bone defects can dramatically alter a person’s appearance. Researchers have developed a “self-fitting” material that expands with warm salt water to precisely fill bone defects, and also acts as a scaffold for new bone growth.

R&D Magazine Announces Scientist and Innovator of the Year Award Winners

August 12, 2014 12:00 pm | by Lindsay Hock, Managing Editor | News | Comments

R&D Magazine introduced its annual Scientist of the Year Award winner, Dr. Karl Deisseroth, and its Innovator of the Year Award winner, Dr. Hugh Herr. As R&D Magazine's 49th Scientist of the Year Award winner, Dr. Deisseroth is one of the United States’ leading researchers in the rapidly growing field of optogenetics, having invented several new technologies in support of efforts to understand neural functions in the human brain.

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