Around 400 BC, Hippocrates was among the first people in recorded history to postulate the brain as the seat of sensation and intelligence. Yet only in the last 100 years have we identified, and closely studied, its key building block: the neuron. A highly specialized cell found in all but the simplest animals, like sponges, the neuron is one of the keys to understanding the brain.
The bionic age is no longer the workings of a far-fetched sci-fi movie; it’s here, now. We have...
Researchers at NYU Langone Medical Center have developed new technology that can assess the...
Researchers for the first time have developed a...
Researchers have devised a way to replace the knee’s protective lining, called the meniscus, using a personalized 3D-printed implant, or scaffold, infused with human growth factors that prompt the body to regenerate the lining on its own. The therapy, successfully tested in sheep, could provide the first effective and long-lasting repair of damaged menisci.
Researchers at Yale Univ. have joined forces with a leading 3-D biology company, Organovo, to develop 3-D printed tissues for transplant research. As the number of donors for vital tissue and organ transplants decreases worldwide and the demand for transplants increases, 3-D bioprinting technology offers a solution to a long-standing and growing problem.
In a study in Neuron, scientists describe a new high data-rate, low-power wireless brain sensor. The technology is designed to enable neuroscience research that cannot be accomplished with current sensors that tether subjects with cabled connections. Experiments in the paper confirm that new capability.
A Univ. of Texas at Dallas professor applied robot control theory to enable powered prosthetics to dynamically respond to the wearer’s environment and help amputees walk. In recently published research, wearers of the robotic leg could walk on a moving treadmill almost as fast as an able-bodied person.
Los Alamos National Laboratory has released an updated version of powerful bioinformatics software that is now capable of identifying DNA from viruses and all parts of the Tree of Life—putting diverse problems such as identifying pathogen-caused diseases, selection of therapeutic targets for cancer treatment and optimizing yields of algae farms within relatively easy reach for health care professionals, researchers and others.
Researchers can now explore viruses, bacteria and components of the human body in more detail than ever before with software developed at The Scripps Research Institute. In a study published online in Nature Methods, the researchers demonstrated how the software, called cellPACK, can be used to model viruses such as HIV.
A team of scientists from Arizona State Univ.’s Biodesign Institute and IBM’s T.J. Watson Research Center have developed a prototype DNA reader that could make whole genome profiling an everyday practice in medicine. Such technology could help usher in the age of personalized medicine, where information from an individual’s complete DNA and protein profiles could be used to design treatments specific to their individual makeup.
Researchers at Tufts Univ., in collaboration with a team at the Univ. of Illinois at Urbana-Champaign, have demonstrated a resorbable electronic implant that eliminated bacterial infection in mice by delivering heat to infected tissue when triggered by a remote wireless signal. The silk and magnesium devices then harmlessly dissolved in the test animals. The technique had previously been demonstrated only in vitro.
Just in time for the holidays, Google is throwing its money, brain power and technology at the humble spoon. Of course these spoons (don't call them spoogles) are a bit more than your basic utensil: Using hundreds of algorithms, they allow people with essential tremors and Parkinson's disease to eat without spilling.
Powered lower limb prosthetics hold promise for improving the mobility of amputees, but errors in the technology may also cause some users to stumble or fall. New research examines exactly what happens when these technologies fail, with the goal of developing a new generation of more robust powered prostheses.
Flexible electronic sensors based on paper have the potential to cut the price of a wide range of medical tools, from helpful robots to diagnostic tests. Scientists have now developed a fast, low-cost way of making these sensors by directly printing conductive ink on paper.
Massachusetts Institute of Technology chemists have developed new nanoparticles that can simultaneously perform magnetic resonance imaging (MRI) and fluorescent imaging in living animals. Such particles could help scientists to track specific molecules produced in the body, monitor a tumor’s environment, or determine whether drugs have successfully reached their targets.
Engineers at Oregon State Univ. have identified a method to rapidly prepare frozen red blood cells for transfusions, which may offer an important new way to manage the world’s blood supply. It’s already possible to cryopreserve human red blood cells in the presence of 40% glycerol, but is rarely done because of the time-consuming process to thaw and remove the glycerol from the blood.
Recovery of feeling can gradually improve for years after a hand transplant, suggests a small study that points to changes in the brain, not just the new hand, as a reason. Research presented at a meeting of the Society for Neuroscience sheds light on how the brain processes the sense of touch, and adapts when it goes awry. The work could offer clues to rehabilitation after stroke, brain injury, maybe one day even spinal cord injury.
Millions of people with stents that prop open clogged heart arteries may need anti-clotting drugs much longer than the one year doctors recommend now. A large study found that continuing for another 18 months lowers the risk of heart attacks, clots and other problems. Even quitting after 30 months made a heart attack more likely, raising a question of when it's ever safe to stop.
A new bloodstream infection test created by Univ. of California, Irvine researchers can speed up diagnosis times with unprecedented accuracy, allowing physicians to treat patients with potentially deadly ailments more promptly and effectively. The technology, called Integrated Comprehensive Droplet Digital Detection, or IC 3D, can detect bacteria in milliliters of blood with single-cell sensitivity in 90 mins; no cell culture is needed.
Needles almost too small to be seen with the unaided eye could be the basis for new treatment options for two of the world’s leading eye diseases: glaucoma and corneal neovascularization. The microneedles, ranging in length from 400 to 700 microns, could provide a new way to deliver drugs to specific areas within the eye relevant to these diseases.
Tiny, thin microtubes could provide a scaffold for neuron cultures to grow so that researchers can study neural networks, their growth and repair, yielding insights into treatment for degenerative neurological conditions or restoring nerve connections after injury. Researchers created the microtube platform to study neuron growth.
Use of “antibiograms” in skilled nursing facilities could improve antibiotic effectiveness and help address problems with antibiotic resistance. Antibiograms are tools that aid health care practitioners in prescribing antibiotics in local populations. They are based on information from microbiology laboratory tests and provide information on how likely a certain antibiotic is to effectively treat a particular infection.
Medicare may soon begin paying for yearly scans to detect lung cancer in certain current or former heavy smokers. The Centers for Medicare and Medicaid Services on Monday issued a long-awaited proposal to begin covering the screening for high-risk beneficiaries if their doctors agree they meet the criteria.
Univ. of Virginia biomedical engineers are building an entire technology around tiny, microscopic bubbles– a technology that has the potential to play an important role in diagnosing as well as treating disease like stroke and cancer.
A diet rich in fruit and vegetables is linked to a variety of improved health outcomes, but accurately measuring consumption by self-report, especially with children, is challenging and can be of questionable validity. But a device being developed in a collaboration that involves researchers from the Yale School of Public Health has the potential to change that.
Researchers are close to commercializing a new type of medical imaging technology that could diagnose cardiovascular disease by measuring ultrasound signals from molecules exposed to a fast-pulsing laser. The system takes precise 3-D images of plaques lining arteries and identifies deposits that are likely to rupture and cause heart attacks.
A new technology that may assist in the treatment of brain cancer and other neurological diseases is the subject of an article in Technology. According to the authors, the current medical use of chemotherapy to treat brain cancer can be inefficient because of the blood-brain-barrier that impedes the delivery of drugs out of blood vessels and into the tumor.
The process of cell division is central to life. The last stage, cytokinesis, when two daughter cells split from each other, has fascinated scientists but has been notoriously difficult to study. Now Harvard Medical School systems biologists report that they have reconstituted cytokinesis, complete with signals that direct molecular traffic, without the cell.
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