Recently, a study team from the First Affiliated Hospital, Sun Yat-sen Univ. in China has verified that virtual reality training using the Kinect system from the Xbox 360 could promote the recovery of upper limb motor function in subacute stroke patients, and brain reorganization by Kinect-based virtual reality training may be linked to the contralateral sensorimotor cortex.
Molecules anchored to the surfaces of nanoparticles modify and even control many characteristics of the particles, including how they interact with cells or react to light. Taking advantage of advanced instrumental capabilities, researchers have built a specially designed experimental cell to successfully deduce the how molecules of carboxylic acid, a common organic acid found in nature, bind to ceria nanoparticle surfaces.
New recommendations for using x-rays promise to speed investigations aimed at understanding the structure of biologically important proteins. In their study, the scientists evaluated options to remedy problems affecting data collection. Scientists who use x-ray beams to study protein crystals face a dilemma: The beams provide the best tool for understanding a protein's structure and biological function, but they often damage the crystal.
Until recently, the microscopic study of complex membrane proteins has been restricted due to limitations of “force microscopes” that are available to researchers and the one-dimensional results these microscopes reveal. Now, researchers at the Univ. of Missouri have built a 3-D microscope that will yield unparalleled information on membrane proteins and how they interact in cells. The innovation could speed up drug development.
Q?rius (pronounced “Curious”) is a new hub of scientific activity and education based at the Smithsonian’s National Museum of Natural History in Washington D.C. The product of a partnership between Olympus and the Smithsonian, the 10,000-square-foot experiential learning center will be equipped with dozens of microscopes and imaging systems that will enable museum visitors more than 6,000 bones, minerals, and fossils.
By using optical techniques, researchers in Switzerland are now able to measure the concentration of the oxidizing substances produced by a damaged cell. This new biosensing technique for toxic agents also offers a new way to know more about the mechanisms of oxidative stress.
Forensic experts have long used the shape of a person’s skull to make positive identifications of human remains. But those findings may now be called into question, since a new study from North Carolina State Univ. shows that there is not enough variation in skull shapes to make a positive identification.
An ultrasonic microscope emits a high frequency sound at an object, and the reflected sound captured by its lens is converted into a 2-D image of the object under scrutiny. Prof. Naohiro Hozumi in Japan is developing the technology to monitor living tissue and cell specimens for medical purposes.
X-rays transformed medicine a century ago by providing a noninvasive way to detect internal structures in the body. Still, they have limitations: X-rays cannot image the body’s soft tissues, except with the use of contrast-enhancing agents that must be swallowed or injected, and their resolution is limited. But a newly developed approach could dramatically change that.
A new nanotechnology-based technique for regulating blood sugar in diabetics may give patients the ability to release insulin painlessly using a small ultrasound device, allowing them to go days between injections—rather than using needles to give themselves multiple insulin injections each day. The technique was developed by researchers at North Carolina State Univ. and the Univ. of North Carolina at Chapel Hill.
Univ. of Michigan researchers are the first to use brain imaging procedures to track the clinical action of pregabalin, a drug known by the brand name Lyrica that is prescribed to patients suffering from fibromyalgia and neuropathic pain. The study suggests role of brain imaging in creating personalized treatment of chronic pain.
Arizona State University is teaming up with seven other research universities to establish a new Science and Technology Center (STC), sponsored by the National Science Foundation. The center will be based at the University at Buffalo. It is expected to transform the field of structural and dynamic molecular biology, including drug development, by using x-ray lasers to peer into biological molecules.
Scientists have developed a 3D filming technique that has brought fresh insights into the behavior of malaria sperm. They were able to see that malaria sperm move in an irregular, lopsided corkscrew motion. Understanding how malaria parasites mate could pave the way for improved prevention and control of this deadly disease.
Researchers at the Univ. of Chicago are developing computer-aided diagnosis and quantitative image analysis methods for mammograms, ultrasounds and magnetic resonance images to identify specific tumor characteristics, including size, shape and sharpness
Most people know about ultrasound through its role in prenatal imaging: those grainy, grey outlines of junior constructed from reflected sound waves. A new technology called an "acoustic diode” that would transmit sound in one direction may dramatically improve future ultrasound images by changing the way sound waves are transmitted.
Microbeam radiation therapy provides tremendous promise for cancer patients through its ability to destroy tumor cells while protecting surrounding healthy tissue. Yet research into its clinical use has been limited by the sheer size of the technology required to generate the beams. Until now.
The increasingly powerful microscopes used in biomedical imaging provide biologists with 3-D images of hundreds of cells, and cells in these images are often layered on each other. Under these conditions, it is impossible for traditional computational methods to determine the cells' properties. Researchers have developed a virtual tool that can analyze dozens of images in just an hour. This works out to hundreds of cells.
Researchers using transmission electron microscopy have examined the smallest building block of coral that can be identified: sphemlites. These studies have revealed three distinct regions whose formation could be directly correlated to the time of day. These findings could help scientists and environmentalists working to protect and conserve coral from the threats of acidification and rising water temperatures.
A lens with ten times the resolution of any current lens, making it a powerful new tool for the biological sciences, has been developed by researchers at the Univ. of Sydney. The lens was created using fiber-optic manufacturing technology, and is a metamaterial, or a material with completely new properties not found in nature.
Dendrites, the branch-like projections of neurons, were once thought to be passive wiring in the brain. But now researchers at the Univ. of North Carolina at Chapel Hill have shown that these dendrites do more than relay information from one neuron to the next. They actively process information, multiplying the brain's computing power.
Researchers in The Netherlands have recently unveiled their “photoacoustic mammoscope,” a new device that could someday be used for routine breast cancer screenings. Instead of x-rays, which are used in traditional mammography, the photoacoustic breast mammoscope uses a combination of infrared light and ultrasound to create a 3-D map of the breast.
OnTarget Laboratories LLC has teamed with partners in academia to test a novel optical imaging technology developed at Purdue Univ. that could help surgeons see cancer tissue during surgery. The technology is based on the over-expression of specific receptors on solid cancerous tumors and enables illumination of the tumor tissue during surgery.
Cell biologists and chemists in Switzerland have revealed how viral DNA moves in human cells. They have developed a new method to generate virus particles containing labeled viral DNA genomes, which has allowed them to visualize, for the first time, single viral genomes in the cytoplasm and the nucleus.
Human fingertips have several types of sensory neurons that are responsible for relaying touch signals to the central nervous system. Scientists have long believed these neurons followed a linear path to the brain with a "labeled-lines" structure. But new research on mouse whiskers reveals a surprise: At the fine scale, the sensory system's wiring diagram doesn't have a set pattern.
During open surgery, doctors rely on their sense of touch to identify anatomical structures: a procedure they call palpation. But this practice is not possible in minimally invasive surgery where surgeons work with small, specialized tools and miniature cameras. A small, wireless capsule has been developed that can restore the sense of touch that surgeons are losing as they shift increasingly from open to minimally invasive surgery.