Imaging technique captures ever-changing world of metabolites
June 13, 2013 7:38 am | News | CommentsWhat would you do with a camera that can take a picture of something and tell you how new it is? If you’re a Lawrence Berkeley National Laboratory scientist, you use it to gain a better understanding of the ever-changing world of metabolites. A team of researchers has developed a mass spectrometry imaging technique that not only maps the whereabouts of individual metabolites in a biological sample, but how new the metabolites are too.
NUS uses JPK Instruments’ optical tweezers
June 4, 2013 8:37 am | News | CommentsJPK Instruments reports on the Yan Jie single-molecule biophysics research group at the Mechanobiology Institute (MBI) of the National Univ. of Singapore (NUS) and their use of optical tweezers. The MBI of the NUS was created through joint funding by the National Research Foundation and the Ministry of Education with the goal of creating a new research center in mechanobiology to benefit both the discipline and Singapore.
New imaging tool directly measures liquid surfaces
May 31, 2013 8:09 am | News | CommentsA unique chemical imaging tool readily and reliably presents volatile liquids to scientific instruments, according to a team including Pacific Northwest National Laboratory. These instruments require samples be held in a vacuum, which is often incompatible with hydrocarbons and other liquids.
Visualization reveals virus particle have more individuality than thought
May 29, 2013 9:01 am | News | CommentsVirus particles of the same type had been thought to have identical structures, like a mass-produced toy, but a new visualization technique developed by a Purdue University researcher revealed otherwise. It was found that an important viral substructure consisted of a collection of components that could be assembled in different ways, creating differences from particle to particle.
Columbia University licenses 3D segmentation software to Varian
May 21, 2013 8:19 am | News | CommentsColumbia University has signed a licensing agreement with Varian Medical Systems for new imaging software that facilitates 3D segmentation, the process by which anatomical structures in medical images are distinguished from one another—an important step in the precise planning of cancer surgery and radiation treatments.
Computational tool simplifies complex data into 2D images
May 20, 2013 9:30 am | News | CommentsResearchers at Columbia University and Stanford University have developed a computational method that enables scientists to visualize and interpret "high-dimensional" data produced by single-cell measurement technologies such as mass cytometry. A sophisticated algorithm converts difficult-to-interpret data into visual representations similar to two-dimensional "scatter plots".
Grammar errors? The brain detects them even when you are unaware
May 14, 2013 10:40 am | News | CommentsYour brain often works on autopilot when it comes to grammar. That theory has been around for years, but University of Oregon neuroscientists have captured elusive hard evidence that people indeed detect and process grammatical errors with no awareness of doing so.
Study looks at muscle adaptations in minimalist runners
May 7, 2013 11:22 am | by Fariss Samarrai, University of Virginia | News | CommentsDespite the perceived advantages of foot protection, some runners in recent years have returned to barefoot running, believing it is a more natural way to run and therefore less injurious to the feet and legs. The difference results in a different running stride, and it affects how the muscles of the legs and feet respond and develop. A new study attempts to explain exactly how the muscles respond to this change.
New imaging technique visualizes bio-metals and molecules simultaneously
May 2, 2013 2:25 pm | by Juliette Savin, RIKEN | News | CommentsMetal elements and molecules interact in the body, but visualizing them together has always been a challenge. Researchers at RIKEN in Japan have developed a new molecular imaging technology that enables them to image bio-metals and bio-molecules at the same time in a live mouse. This new technology will enable researchers to study the complex interactions between metal elements and molecules in living organisms.
New imaging technique to visualize biometals and molecules
May 2, 2013 10:29 am | News | CommentsMetal elements and molecules interact in the body but visualizing them together has always been a challenge. Researchers from the RIKEN Center for Life Science Technologies have developed a new molecular imaging technology that enables them to visualize biometals and biomolecules simultaneously in a live mouse. This new technology will enable researchers to study the complex interactions between metal elements and molecules.
Important microscopic technique advanced for biomedical research
April 29, 2013 8:17 am | News | CommentsScientists at TU Delft have made an important advancement in a new microscopic technique that is widely used in medical research. They demonstrate what the resolution of this localization microscopy is and how the best resolution can be achieved as quickly as possible.
Imaging technology could reveal cellular secrets
April 25, 2013 2:30 pm | News | CommentsResearchers have married two biological imaging technologies, creating a new way to learn how good cells go bad. Being able to study a cell's internal workings in fine detail would likely yield insights into the physical and biochemical responses to its environment. The technology, which combines an atomic force microscope and nuclear magnetic resonance system, could help researchers study individual cancer cells.
Study aims to understand how neurons represent the world
April 23, 2013 11:49 am | News | CommentsTo understand the development of sensory representations within our brain, we have to comprehend how electrical activation is linked to the sensory experience. For this reason, researchers in Italy have analyzed the behavior and the activation of neural networks in rats while carrying out tactile object recognition tests. The study represents the first time that the activity of multiple neurons has been monitored.
Researchers find out why some stress is good for you
April 17, 2013 7:19 am | by Robert Sanders, UC Berkeley | News | CommentsMuch research has demonstrated that chronic stress elevates levels of glucocorticoid stress hormones, which impairs memory. And stress is associated with a lot of other physical ailments. But less is known about the effects of acute stress, and studies have been conflicting. Recent work shows that intense, short-lived stress causes the proliferation of new neurons, improving mental performance.
Scientists learn what makes nerve cells so strong
April 16, 2013 11:05 am | News | CommentsHow do nerve cells—which can each be up to three feet long in humans—keep from rupturing or falling apart? Recent research reports that axons, the long, cable-like projections on neurons, are made stronger by a unique modification of the common molecular building block of the cell skeleton. The finding may help guide the search for treatments for neurodegenerative diseases.
X-ray approach devised to track surgical devices
April 16, 2013 8:20 am | News | CommentsResearchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed a new tool to help surgeons use X-rays to track devices used in “minimally invasive” surgical procedures while also limiting the patient’s exposure to radiation from the X-rays.
Tiny, injectable LEDs help neuroscientists study the brain
April 11, 2013 5:28 pm | News | CommentsA new class of tiny, injectable light-emitting diodes (LEDs) is illuminating the deep mysteries of the brain. Researchers at the University of Illinois at Urbana-Champaign and Washington University in St. Louis developed ultrathin, flexible optoelectronic devices—including LEDs the size of individual neurons—that are lighting the way for neuroscientists in the field of optogenetics and beyond.
Doctors use brain scans to “see” and measure pain
April 11, 2013 3:24 am | by Marilynn Marchione, AP Chief Medical Writer | News | CommentsIn a provocative new study, scientists reported Wednesday that they were able to "see" pain on brain scans and, for the first time, measure its intensity and tell whether a drug was relieving it. Though the research is in its early stages, it opens the door to a host of possibilities. For example, scans might be used someday to tell when pain is hurting a baby, someone with dementia, or a paralyzed person unable to talk.
MRI-guided laser treatment for brain tumors is promising
April 5, 2013 4:37 pm | News | CommentsThe NeuroBlate Thermal Therapy System is a new device that uses a minimally invasive, magnetic resonance imaging (MRI)-guided laser system to coagulate, or heat and kill, brain tumors. The MRI basically "cooks" brain tumors in a controlled fashion to destroy them. The first-in-human study of the system finds that it appears to provide a new, safe and minimally invasive procedure for treating recurrent glioblastoma, a malignant type of brain tumor.
ORNL's awake imaging device moves diagnostics field forward
April 4, 2013 12:13 pm | News | CommentsA technology being developed at Oak Ridge National Laboratory promises to provide clear images of the brains of children, the elderly, and people with Parkinson's and other diseases without the use of uncomfortable or intrusive restraints. Awake imaging provides motion compensation reconstruction, which removes blur caused by motion, allowing physicians to get a transparent picture of the functioning brain without anesthetics that can mask conditions and alter test results.
Telerobotic system designed to treat bladder cancer
April 3, 2013 9:18 am | by David Salisbury, Vanderbilt University | News | CommentsAlthough bladder cancer is the sixth most common form of cancer in the U.S. and the most expensive to treat, the basic method that doctors use to treat it hasn’t changed much in more than 70 years. A research team may soon be changing that dramatically after having developed a prototype telerobotic platform designed to be inserted through natural orifices—in this case the urethra—that can provide surgeons with a much better view, making it easier to remove tumors.
Switch to a power stroke enables tiny marine crustacean to survive
April 2, 2013 12:59 pm | News | CommentsOlympic swimmers aren’t the only ones who change their strokes to escape competitors. To escape from the jaws and claws of predators in cold, viscous water, marine copepods switch from a wave-like swimming stroke to big power strokes, a behavior that has now been revealed thanks to 3D high-speed digital holography.
Nanotechnology research study turns brain tumors blue
March 27, 2013 11:46 am | News | CommentsResearchers from Georgia Tech and Children's Healthcare of Atlanta have developed a technique that assists in identifying tumors from normal brain tissue during surgery by staining tumor cells blue. The technique could be critically important for hospitals lacking sophisticated equipment in preserving the maximum amount of normal tissue and brain function during surgery.
New method may sharpen microscopic images
March 22, 2013 11:32 am | News | CommentsUniversity of Texas, Dallas researchers are developing a new low-light imaging method that could improve a number of scientific applications, including the microscopic imaging of single molecules in cancer research. The team's method minimizes the deterioration of images that can occur with conventional imaging approaches.
Cryo-electron microscopy unlocks biochemical methane production
March 20, 2013 2:17 pm | News | CommentsThe biological sources of methane are wide-ranging. However, the conditions have to be always oxygen-free and the exact mechanism has been unclear. A team of researchers in Germany has gained insight into microbiological methane production by explaining the structure of a hydrogenase used by archaebacteria to split hydrogen to produce methane



