New achievements in synthetic biology, which will allow complex cellular recognition reactions to proceed outside of living cells, will dare scientists to dream big: There could one day be inexpensive, shippable and accurate test kits that use saliva or a drop of blood to identify specific disease or infection.
The federal government is closing a gap in Ebola screening at airports while states from New...
Scientists think of CD8 T cells as long-lived cells that become tuned to fight just one pathogen...
Federal health officials on Monday issued new guidelines to promote head-to-toe protection for health workers treating Ebola patients. Officials have been scrambling to come up with new advice for protective gear since two Dallas nurses became infected while caring for the first person diagnosed with the virus in the U.S.
European Union nations are working to reach 1 billion euros ($1.27 billion) in aid by the end of the week to fight Ebola in West Africa and are seeking a common approach to the crisis.EU foreign ministers began a week of talks Monday so their 28 leaders can agree by Friday on better measures to fight Ebola, anything from financial aid to common repatriation procedures, more Ebola treatment facilities and better training for health workers.
Ebola fears began to ease for some Monday as a monitoring period passed for those who had close contact with a victim of the disease and after a cruise ship scare ended with the boat returning to port and a laboratory worker on board testing negative for the virus. Federal officials meanwhile ramped up readiness to deal with future cases.
Scientists have used computer simulations to show how bacteria are able to destroy antibiotics, a breakthrough which will help develop drugs which can effectively tackle infections in the future. Researchers at the Univ. of Bristol focused on the role of enzymes in the bacteria, which split the structure of the antibiotic and stop it working, making the bacteria resistant.
The new Urban Dynamics Institute at Oak Ridge National Laboratory is working with the Bill & Melinda Gates Foundation to aid polio vaccination efforts in developing countries. Teams at the institute will apply big data analysis to population dynamics in Nigeria, allowing polio vaccination crews to better estimate the amount of vaccine needed and to target areas of priority, saving time and money in eradicating the disease.
Buoyed by several dramatic advances, Lawrence Livermore National Laboratory (LLNL) scientists think they can tackle biological science in a way that couldn't be done before. Over the past two years, LLNL researchers have expedited accelerator mass spectrometer sample preparation and analysis time from days to minutes and moved a complex scientific process requiring accelerator physicists into routine laboratory usage.
Researchers are exploring the usefulness of ultrasound imaging to study dangerous abdominal aortic aneurysms, a bulging of the aorta that is usually fatal when it ruptures and for which there is no effective medical treatment. Abdominal aortic aneurysms are the 13th leading cause of death in the U.S., killing about 15,000 annually.
Researchers from the Univ. of Sheffield have found vital new evidence on how to target and reverse the effects caused by one of the most common genetic causes of Parkinson’s. Mutations in a gene called LRRK2 carry a well-established risk for Parkinson’s disease, however the basis for this link is unclear.
A new study by scientists from The Scripps Research Institute, Lawrence Berkeley National Laboratory and other institutions suggests a cause of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. The team's work supports a common theme whereby loss of protein stability leads to disease.
President Barack Obama urged his top national security and public health officials on Monday to incorporate lessons from the most recent Texas Ebola infection into the U.S.'s response plans to the deadly virus. He also called on the international community to deliver assistance more quickly to the countries of West Africa that are struggling against the disease.
The Centers for Disease Control and Prevention has said that at least 2 million Americans are sickened by antibiotic resistant infections each year and survive. Twenty-three thousand die. These experiences leave deep impressions not just on the patients but on their family and friends.
A breach of infection control resulting in a Dallas health worker getting Ebola raises fresh questions about whether hospitals truly can safely take care of people with the deadly virus, as health officials insist is possible. Even in the U.S., with the best conditions and protective gear available, mistakes can happen that expose more people to Ebola, the new case reveals.
Autism is characterized by many different symptoms: difficulty interacting with others, repetitive behaviors and hypersensitivity to sound and other stimuli. Massachusetts Institute of Technology neuroscientists have put forth a new hypothesis that accounts for these behaviors and may provide a neurological foundation for many of the disparate features of the disorder.
Hepatitis C, an infectious disease of the liver caused by the hepatitis C virus (HCV), affects 160 million people worldwide. There’s no vaccine for HCV and the few treatments that are available do not work on all variants of the virus. Before scientists can develop potential vaccines and additional therapies they must first thoroughly understand the molecular-level activity that takes place when the virus infects a host cell.
HIV is adept at eluding immune system responses because the protein it uses to infect cells is constantly changing. Now a team of researchers including scientists from Yale Univ. have stripped the cloak from this master of disguise, providing a high-resolution image of this surface spike protein and monitoring how it constantly changes its shape, information that suggests new ways to attack the virus through drugs and vaccines.
Tuberculosis is caused by a bacterium that infects the lungs of an estimated 8.6 million people worldwide. The fight against the disease is hampered by the fact that treatment requires a long time and that the bacterium often develops multi-drug resistance. Scientists have used a sensitive screening assay to test new compounds that can be used against the bacterium, and have discovered two small molecules that show remarkable promise.
The first person diagnosed with Ebola in the U.S. died Wednesday despite intense but delayed treatment, and the government announced it was expanding airport examinations to guard against the spread of the deadly disease. The checks will include taking the temperatures of hundreds of travelers arriving from West Africa at five major American airports.
A study suggests that do-it-yourself flu vaccine might be possible. Researchers found that military folks who squirted a nasal vaccine up their noses were as well-protected as others who got it from health workers. The study leader says there is no reason that ordinary people could not be taught to give the vaccine, especially for children who might be less scared if they received it from mom or dad.
Metabolic networks are mathematical models of every possible sequence of chemical reactions available to an organ or organism, and they’re used to design microbes for manufacturing processes or to study disease. Based on both genetic analysis and empirical study, they can take years to assemble. Unfortunately, a new analytic tool suggests that many of those models may be wrong.
Ebola's victims may include a dog named Excalibur. Officials in Madrid got a court order to euthanize the pet of a Spanish nursing assistant with Ebola because of the chance the animal might spread the disease. At least one major study suggests that dogs can be infected with the deadly virus without having symptoms. But whether or how likely they are to spread it to people is less clear.
Until now, researchers searching for compounds that have the potential to become a new HIV drug have been hampered by slow computers and inaccurate prediction models. Now, researchers in Denmark have developed an effective model based on quantum mechanics and molecular mechanics that has found, out of a half-million compounds, 14 of interest in just weeks.
Texas health officials have confined four people to their home, under guard, after they had close contact with an Ebola patient hospitalized in Dallas, as disease detectives work to make sure the deadly virus doesn't spread in the U.S. Five things to know about containing the virus: 1. WHY ORDER...
Federal health officials on Tuesday confirmed the first case of Ebola diagnosed in the U.S., a patient who recently traveled from Liberia to Dallas and a sign of the far-reaching impact of the out-of-control epidemic in West Africa. The unidentified patient was critically ill and has been in isolation at Texas Health Presbyterian Hospital since Sunday, officials said.
Researchers at the Univ. of Michigan have described a new approach to discovering potential cancer treatments that requires a fraction of the time needed for more traditional methods. They used the platform to identify a novel antibody that is undergoing further investigation as a potential treatment for breast, ovarian and other cancers.
Over the past few years, a class of compounds called ADEPs (cyclic acyldepsipeptides) has emerged as a promising new weapon in the fight against drug-resistant bacteria. The compounds work by attaching themselves to a cellular enzyme called ClpP, which bacterial cells use to rid themselves of harmful proteins. With an ADEP attached, ClpP can’t function properly, and the bacterial cell dies.
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