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CDC study: Americans' bellies are expanding fast

September 16, 2014 4:37 pm | by Lindsey Tanner - AP Medical Writer - Associated Press | News | Comments

The number of American men and women with big-bellied, apple-shaped figures—the most dangerous kind of obesity—has climbed at a startling rate over the past decade, according to a government study. People whose fat has settled mostly around their waistlines instead of in their hips, thighs, buttocks or all over are known to run a higher risk of heart disease, diabetes and other obesity-related ailments.

Is the U.S. doing enough to fight Ebola?

September 16, 2014 11:46 am | by Lauran Neergaard, The Associated Press | News | Comments

The American strategy on Ebola is two-pronged: step up desperately needed aid to West Africa and...

Muscular dystrophy: Repair the muscles, not the genetic defect

September 16, 2014 7:52 am | by Laura Bailey, Univ. of Michigan | News | Comments

A potential way to treat muscular dystrophy directly targets muscle repair instead of the...

New glaucoma cause discovered

September 15, 2014 10:57 am | by Marla Paul, Northwestern Univ. | News | Comments

Northwestern Medicine scientists have discovered a novel cause of glaucoma in an animal model,...

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Researchers find neural compensation in people with Alzheimer’s-related protein

September 15, 2014 10:43 am | by Sarah Yang, Media Relations, UC Berkeley | News | Comments

The human brain is capable of a neural workaround that compensates for the buildup of beta-amyloid, a destructive protein associated with Alzheimer’s disease, according to a new study led by Univ. of California, Berkeley researchers. The findings could help explain how some older adults with beta-amyloid deposits in their brain retain normal cognitive function while others develop dementia.

Taking a Big Bite Out of Malaria

September 15, 2014 9:49 am | by Lindsay Hock, Managing Editor | Articles | Comments

Malaria threatens more than 40% of the world’s population and kills up to 1.2 million people worldwide each year. Many of these deaths happen in Sub-Saharan Africa in children under the age of five and pregnant woman. The estimates for clinical infection is somewhere between 300 to 500 million people each year, worldwide.

Gilead to license generic version of Sovaldi

September 15, 2014 9:37 am | by Tom Murphy - AP Business Writer - Associated Press | News | Comments

Gilead Sciences has reached a deal with several generic drugmakers to produce a cheaper version of its popular, $1,000-per-pill hepatitis C drug Sovaldi for use in developing countries. Gilead said that the India-based companies will make a generic version of Sovaldi, also known as sofosbuvir, and another investigational drug for distribution in 91 countries.

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Blood-cleansing biospleen device developed for sepsis therapy

September 15, 2014 8:21 am | by Kristen Kusek, Wyss Institute for Biologically Inspired Engineering, Harvard Univ. | News | Comments

Things can go downhill fast when a patient has sepsis, a life-threatening condition in which bacteria or fungi multiply in a patient's blood—often too fast for antibiotics to help. A new device inspired by the human spleen and developed by a team at Harvard's Wyss Institute for Biologically Inspired Engineering may radically transform the way doctors treat sepsis.

Rapid point-of-care anemia test shows promise

September 12, 2014 8:22 am | by John Toon, Georgia Institute of Technology | News | Comments

A simple point-of-care testing device for anemia could provide more rapid diagnosis of the common blood disorder and allow inexpensive at-home self-monitoring of persons with chronic forms of the disease. The disposable self-testing device analyzes a single droplet of blood using a chemical reagent that produces visible color changes corresponding to different levels of anemia.

Study: Many hospitals use too many antibiotics

September 11, 2014 8:39 am | by Mike Stobbe - AP Medical Writer - Associated Press | News | Comments

Doctors in many U.S. hospitals are unnecessarily prescribing multiple antibiotics for several days when just one would do the job, a new study suggests. Health officials have sounded alarms that overuse of antibiotics is helping to breed dangerous bacteria that are increasingly resistant to treatment. Much of the attention has been on doctor offices that wrongly prescribe bacteria-targeting antibiotics for illnesses caused by viruses.

Serious respiratory illness hits hundreds of kids

September 8, 2014 1:26 pm | by Lindsey Tanner - AP Medical Writer - Associated Press | News | Comments

Hundreds of children in about a dozen states have been sickened by a severe respiratory illness that public health officials suspect may be caused by an uncommon virus similar to the germ that causes the common cold. Nearly 500 children have been treated at one hospital alone—Children's Mercy in Kansas City—and some required intensive care, according to authorities.

NIH finds more forgotten samples in labs

September 8, 2014 12:09 pm | by Lauran Neergaard, Associated Press | News | Comments

The National Institutes of Health said it has uncovered a nearly century-old container of ricin and a handful of other forgotten samples of dangerous pathogens as it combs its laboratories for improperly stored hazardous materials. The agency began an intensive investigation of all its facilities after a scientist in July found vials of smallpox dating from the 1950s.

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Parkinson's, cancer findings earn medical prizes

September 8, 2014 9:25 am | by Malcolm Ritter - AP Science Writer - Associated Press | News | Comments

Key discoveries about breast cancer, Parkinson's disease and the body's handling of defective proteins have earned prestigious medical awards for five scientists. The Albert and Mary Lasker Foundation announced the winners Monday. Each prize includes a $250,000 honorarium. The awards will be presented Sept. 19 in New York.

Researchers turn to plants to help treat hemophilia

September 4, 2014 1:02 pm | by April Frawley Birdwell, Univ. of Florida | News | Comments

Up to 30% of people with the most common form of hemophilia develop antibodies that attack lifesaving protein injections, making it difficult to prevent or treat excessive bleeding. Now researchers have developed a way to thwart production of these antibodies by using plant cells to teach the immune system to tolerate rather than attack the clotting factors.

Lilly says insulin fares well in late-stage tests

September 4, 2014 11:27 am | by The Associated Press | News | Comments

Eli Lilly and Co. plans to seek approval early next year for a new insulin it developed after the diabetes treatment fared better than the competition in two late-stage clinical studies. The Indianapolis drugmaker said Thursday peglispro produced statistically significant lower blood sugar levels in patients when compared to people who took the Sanofi insulin Lantus in two late-stage studies of people with type 1 diabetes.

Researcher’s nanoparticle key to new malaria vaccine

September 4, 2014 11:26 am | by Colin Poitras, UConn | News | Comments

A self-assembling nanoparticle designed by a Univ. of Connecticut (UConn) professor is the key component of a potent new malaria vaccine that is showing promise in early tests. For years, scientists trying to develop a malaria vaccine have been stymied by the malaria parasite’s ability to transform itself and “hide” in the liver and red blood cells of an infected person to avoid detection by the immune system.

Scientists make diseased cells synthesize their own drug

September 3, 2014 8:34 am | News | Comments

In a new study that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute (TSRI) have adapted a chemical approach to turn diseased cells into unique manufacturing sites for molecules that can treat a form of muscular dystrophy.

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Sabotage as therapy

September 3, 2014 8:00 am | by Vicky Agnew, Yale Univ. | News | Comments

Yale Cancer Center researchers may have discovered a new way of harnessing lupus antibodies to sabotage cancer cells made vulnerable by deficient DNA repair. The study found that cancer cells with deficient DNA repair mechanisms (or the inability to repair their own genetic damage) were significantly more vulnerable to attack by lupus antibodies.

Scientists discover how to “switch off” autoimmune diseases

September 3, 2014 7:50 am | by Univ. of Bristol | News | Comments

Scientists have made an important breakthrough in the fight against debilitating autoimmune diseases such as multiple sclerosis by revealing how to stop cells attacking healthy body tissue. Rather than the body’s immune system destroying its own tissue by mistake, researchers at the Univ. of Bristol have discovered how cells convert from being aggressive to actually protecting against disease.

Double mastectomy doesn't boost survival for most

September 2, 2014 4:26 pm | by Lindsey Tanner - AP Medical Writer - Associated Press | News | Comments

Removing both breasts to treat cancer affecting only one side doesn't boost survival chances for most women, compared with surgery that removes just the tumor, a large study suggests. The results raise concerns about riskier, potentially unnecessary operations that increasing numbers of women are choosing.

Ebola genomes sequenced

September 2, 2014 10:28 am | by Lisa Girard, Broad Institute Communication | News | Comments

Responding rapidly to the deadly outbreak of Ebola virus disease (EVD) in West Africa, a team of researchers from the Broad Institute and Harvard Univ., working with the Sierra Leone Ministry of Health and Sanitation and researchers elsewhere, has sequenced and analyzed many Ebola virus genomes. Their findings could have important implications for rapid field diagnostic tests.

Research hints at why stress is more devastating for some

September 2, 2014 9:52 am | by Rockefeller Univ. | News | Comments

Some people take stress in stride; others are done in by it. New research at Rockefeller Univ. has identified the molecular mechanisms of this so-called stress gap in mice with very similar genetic backgrounds—a finding that could lead researchers to better understand the development of psychiatric disorders such as anxiety and depression.

A new way to diagnose malaria

September 2, 2014 7:38 am | by Anne Trafton, MIT News Office | News | Comments

Over the past several decades, malaria diagnosis has changed very little. After taking a blood sample from a patient, a technician smears the blood across a glass slide, stains it with a special dye and looks under a microscope for the Plasmodium parasite, which causes the disease. This approach gives an accurate count of how many parasites are in the blood, but is not ideal because there is potential for human error.

Experimental Ebola drug heals all monkeys in study

August 29, 2014 1:28 pm | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

An experimental Ebola drug healed all 18 monkeys infected with the deadly virus in a study, boosting hopes that the treatment might help fight the outbreak raging through West Africa. Scientists gave the drug, called ZMapp, three to five days after infecting the monkeys in the laboratory. Most were showing symptoms by then, and all completely recovered.

We travel with our own germs

August 29, 2014 5:24 am | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

Sorry, clean freaks. No matter how well you scrub your home, it's covered in bacteria from your own body. And if you pack up and move, new research shows, you'll rapidly transfer your unique microbial fingerprint to the doorknobs, countertops and floors in your new house, too.

Sensory-tested drug delivery vehicle could limit spread of HIV, AIDS

August 28, 2014 12:33 pm | by Jeff Mulhollem, Penn State Univ. | News | Comments

A unique method for delivering compounds that could positively impact the global battle against HIV and AIDS may be possible, thanks to researchers in Penn State's College of Agricultural Sciences. A semi-soft vaginal suppository made from the seaweed-derived food ingredient carrageenan and loaded with the antiviral drug Tenofovir provides a woman-initiated, drug delivery vehicle that can protect against the spread of STIs.

U.S. to begin safety testing Ebola vaccine next week

August 28, 2014 9:25 am | by Seth Borenstein - AP Science Writer - Associated Press | News | Comments

Federal researchers next week will start testing humans with an experimental vaccine to prevent the deadly Ebola virus. The National Institutes of Health announced Thursday that it is launching the safety trial on a vaccine developed by the agency's National Institute of Allergy and Infectious Diseases and GlaxoSmithKline.

Breakthrough antibacterial approach could resolve serious skin infections

August 26, 2014 4:30 pm | by Nancy Ambrosiano, Los Alamos National Laboratory | News | Comments

Like a protective tent over a colony of harmful bacteria, biofilms make the treatment of skin infections especially difficult. Microorganisms protected in a biofilm pose a significant health risk due to their antibiotic resistance and recalcitrance to treatment, and biofilm-protected bacteria account for 80% of total bacterial infections in humans and are 50 to 1,000 times more resistant to antibiotics than simpler bacterial infections.

Vision problems for older adults can dim life expectancy

August 26, 2014 11:28 am | by Amy Patterson Neubert, Purdue Univ. | News | Comments

Older adults losing vision as they age are more likely to face an increased mortality risk, according to new research from Purdue Univ. The researchers analyzed data from the Salisbury Eye Evaluation study that tracked the vision health of 2,520 older adults, ages 65 to 84. The research was funded by the National Eye Institute.

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