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Coffee may fight gum disease

August 22, 2014 10:38 am | by Boston Univ. | News | Comments

Coffee contains antioxidants. Antioxidants fight gum disease. Researchers in dental medicine have found that coffee consumption does not have an adverse effect on periodontal health, and may have protective effects against periodontal disease.

Vault nanoparticles show promise for cancer treatment, potential HIV cure

August 22, 2014 9:47 am | by Shaun Mason, Univ. of California, Los Angeles | News | Comments

A multidisciplinary team of scientists from the Univ. of California, Los Angeles and Stanford...

Laser device may end pin pricks for diabetics

August 22, 2014 8:07 am | by John Sullivan, Office of Engineering Communications, Princeton Univ. | News | Comments

Princeton Univ. researchers have developed a way to use a laser to measure people's blood sugar...

American Ebola doctor urges help fighting outbreak

August 22, 2014 4:25 am | by Kathleen Foody - Associated Press - Associated Press | News | Comments

As one of few Ebola survivors with medical expertise, Dr. Kent Brantly seems keenly aware of the...

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TB Be Gone

August 21, 2014 4:27 pm | Award Winners

MDR-TB is a growing problem, estimated to kill 170,000 people annually and projected to infect more than two million people between 2011 and 2015. Janssen Research & Development LLC’s bedaquiline represents a significant scientific and public health advancement in the treatment of MDR-TB, as the first available medicine developed specifically for pulmonary MDR-TB treatment.

Study: Combining vaccines boosts polio immunity

August 21, 2014 3:25 pm | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

New research suggests a one-two punch could help battle polio in some of the world's most remote and strife-torn regions: Giving a single vaccine shot to children who've already swallowed drops of an oral polio vaccine greatly boosted their immunity. The World Health Organization officials said the combination strategy already is starting to be used in mass vaccination campaigns in some hard-hit areas.

Drug for Ebola-like virus promising in ill monkeys

August 20, 2014 3:23 pm | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

Texas researchers are reporting that an experimental drug saved monkeys from a virus closely related to Ebola even after symptoms began. The drug targets a strain of Marburg virus that is even more lethal than the Ebola currently ravaging West Africa. Both viruses take time to multiply in the body before symptoms appear, and few studies have explored how late treatment might be effective.

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AstraZeneca says DOJ closes probe into drug trial

August 19, 2014 1:23 pm | by The Associated Press | News | Comments

British drugmaker AstraZeneca says the U.S. Dept. of Justice has closed its investigation into a clinical trial of the company's blood thinner Brilinta, and plans no further action. The company announced in October 2013 that federal officials were looking into the 18,000-patient study, which began in 2009.

Worm virus details come to light

August 19, 2014 8:10 am | by Mike Williams, Rice Univ. | News | Comments

Rice Univ. scientists have won a race to find the crystal structure of the first virus known to infect the most abundant animal on Earth. The Rice laboratories of structural biologist Yizhi Jane Tao and geneticist Weiwei Zhong, with help from researchers at Baylor College of Medicine and Washington Univ., analyzed the Orsay virus that naturally infects a certain type of nematode, the worms that make up 80% of the living animal population.

Disabilities in kids rise; not physical problems

August 18, 2014 2:19 am | by Lindsey Tanner - AP Medical Writer - Associated Press | News | Comments

Disabilities among U.S. children have increased slightly, with a bigger rise in mental and developmental problems in those from wealthier families, a 10-year analysis found. Disadvantaged kids still bear a disproportionate burden. The increases may partly reflect more awareness and recognition that conditions, including autism, require a specific diagnosis to receive special services, the researchers said.

Another Ebola problem: Finding its natural source

August 17, 2014 9:19 am | by Mike Stobbe - AP Medical Writers - Associated Press | News | Comments

A scary problem lurks beyond the frenzied efforts to keep people from spreading Ebola: No one knows exactly where the virus comes from or how to stop it from seeding new outbreaks. Ebola has caused two dozen outbreaks in Africa since it first emerged in 1976. It is coming from somewhere—probably bats—but experts agree they need to pinpoint its origins in nature.

Report: CDC scientist kept quiet about flu blunder

August 15, 2014 12:23 pm | by Mike Stobbe - AP Medical Writer - Associated Press | News | Comments

An investigation into a potentially dangerous blunder at a government lab found that a scientist kept silent about the accident and revealed it only after other employees noticed something fishy. Officials on Friday released the results of an internal probe into the accident, which happened in January at the Centers for Disease Control and Prevention in Atlanta.

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Scientists racing to test Ebola vaccines in humans

August 14, 2014 6:22 pm | by Matthew Perrone - Associated Press - Associated Press | News | Comments

Scientists are racing to begin the first human safety tests of two experimental Ebola vaccines, but it won't be easy to prove that the shots and other potential treatments in the pipeline really work. There are no proven drugs or vaccines for Ebola, a disease so rare that it's been hard to attract investments in countermeasures. But the current outbreak in West Africa is fueling new efforts to speed Ebola vaccine and drug development.

Panel urges second pneumonia shot for older adults

August 13, 2014 5:20 pm | by Mike Stobbe - AP Medical Writer - Associated Press | News | Comments

A federal panel says older Americans should start getting a new vaccine against bacteria that cause pneumonia. The Advisory Committee on Immunization Practices voted Wednesday to recommend a dose of the expensive new shot for people 65 and older. The panel said older adults should still get an older pneumococcal vaccine, too.

A Potential New Route to Stopping Surgical Bleeding

August 13, 2014 10:44 am | by Lindsay Hock, Managing Editor | Articles | Comments

Surgical and trauma patients are at significant risk for morbidity and mortality from bleeding and/or leaking bodily fluids. With the number and complexity of surgeries rising, so is the need for better hemostatic agents to stop bleeding as quickly as possible. The history of approaches to hemostasis goes back to when people simply used their hands or a tool to apply to a wound to stop bleeding.

An easier way to manipulate malaria genes

August 11, 2014 10:35 am | by Anne Trafton, MIT News Office | News | Comments

Plasmodium falciparum, the parasite that causes malaria, has proven notoriously resistant to scientists’ efforts to study its genetics. It can take up to a year to determine the function of a single gene, which has slowed efforts to develop new, more targeted drugs and vaccines. Biological engineers have now demonstrated a new genome-editing technique that can disrupt a single parasite gene in a matter of weeks.

Ebola outbreak is a public health emergency

August 8, 2014 10:23 am | by Maria Cheng - AP Medical Writer - Associated Press | News | Comments

The World Health Organization on Friday declared the Ebola outbreak in West Africa to be an international public health emergency that requires an extraordinary response to stop its spread. It is the largest and longest outbreak ever recorded of Ebola, which has a death rate of about 50% and has so far killed at least 961 people. WHO declared similar emergencies for the swine flu pandemic in 2009 and for polio in May.

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Scientists use lasers, carbon nanotubes to look inside living brains

August 8, 2014 8:19 am | by Bjorn Carey, Stanford News Service | News | Comments

Some of the most damaging brain diseases can be traced to irregular blood delivery in the brain. Now, Stanford Univ. chemists have employed lasers and carbon nanotubes to capture an unprecedented look at blood flowing through a living brain. The technique was developed for mice but could one day be applied to humans, potentially providing vital information in the study of stroke and migraines.

Cell signaling pathway linked to obesity, Type 2 diabetes

August 8, 2014 7:55 am | by Natalie van Hoose, Purdue Univ. | News | Comments

A Purdue Univ. study shows that Notch signaling, a key biological pathway tied to development and cell communication, also plays an important role in the onset of obesity and Type 2 diabetes, a discovery that offers new targets for treatment. The research team found that blocking Notch signaling in the fat tissue of mice caused white fat cells to transform into a "leaner" type of fat known as beige fat.

CDC director: Scale of Ebola crisis unprecedented

August 7, 2014 4:25 pm | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

The current Ebola crisis in West Africa is on pace to sicken more people than all other previous outbreaks of the disease combined, a U.S. health official said Thursday. Dr. Tom Frieden, director of the Centers for Disease Control and Prevention, told a congressional hearing that the outbreak is unprecedented in part because it's in a region of Africa that never has dealt with Ebola before.

Bad bite: A tick can make you allergic to red meat

August 7, 2014 2:53 pm | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

A bug can turn you into a vegetarian, or at least make you swear off red meat. Doctors across the nation are seeing a surge of sudden meat allergies in people bitten by a certain kind of tick. This bizarre problem was only discovered a few years ago but is growing as the ticks spread from the Southwest and the East to more parts of the United States.

In search for Alzheimer’s drug, a major STEP forward

August 7, 2014 8:10 am | by Karen N. Peart, Yale Univ. | News | Comments

Researchers at Yale School of Medicine have discovered a new drug compound that reverses the brain deficits of Alzheimer’s disease in an animal model. The compound, TC-2153, inhibits the negative effects of a protein called STtriatal-Enriched tyrosine Phosphatase (STEP), which is key to regulating learning and memory. These cognitive functions are impaired in Alzheimer’s.

A new way to model cancer

August 7, 2014 7:45 am | by Anne Trafton, MIT News Office | News | Comments

Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that carry the genetic flaw—but breeding such mice is an expensive, time-consuming process. Now, Massachusetts Institute of Technology researchers have found an alternative.

Study ties new gene to major breast cancer risk

August 6, 2014 5:25 pm | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

It's long been known that faulty BRCA genes greatly raise the risk for breast cancer. Now scientists say a more recently identified, less common gene can do the same. Mutations in the gene can make breast cancer up to nine times more likely to develop, an international team of researchers reports in the New England Journal of Medicine.

Ethical issue: Who gets experimental Ebola drug?

August 6, 2014 5:25 pm | by Lauran Neergaard - AP Medical Writer - Associated Press | News | Comments

The use of an experimental drug to treat two Americans diagnosed with Ebola is raising ethical questions about who gets first access to unproven new therapies for the deadly disease. But some health experts fear debate over extremely limited doses will distract from tried-and-true measures to curb the growing outbreak.

Cytori halts stem cell study due to adverse events

August 5, 2014 5:23 pm | by Matthew Perrone - AP Health Writer - Associated Press | News | Comments

Cytori Therapeutics said Tuesday it has halted trials of its experimental stem cell therapy for heart failure after three patients developed blood flow problems. The San Diego-based company said it placed the hold on two studies after the patients developed problems with blood flow to the brain. Two of the patients' symptoms resolved in a short period of time and a third was still recovering, the company said in a statement.

Model of viral lifecycle could help find cure for hepatitis B

August 5, 2014 4:36 pm | by Helen Knight, MIT News correspondent | News | Comments

A new technique for studying the lifecycle of the hepatitis B virus could help researchers develop a cure for the disease. A recently published paper describes using microfabricated cell cultures to sustain hepatitis B virus in human liver cells, allowing them to study immune responses and drug treatments.

NYC hospital testing patient for possible Ebola

August 4, 2014 6:22 pm | by Frank Eltman - Associated Press - Associated Press | News | Comments

A man who recently visited West Africa was placed in isolation at a city hospital and was undergoing tests for possible Ebola, officials said Monday. The man, suffering from a high fever and gastrointestinal symptoms, arrived at Mount Sinai Medical Center in Manhattan early on Monday, the hospital said. He had recently traveled to a West African country where Ebola has been reported, it said.

Researchers uncover clues to flu’s mechanisms

August 4, 2014 3:13 pm | by Mike Williams, Rice Univ. | News | Comments

A flu virus acts like a Trojan horse as it attacks and infects host cells. Scientists at Rice Univ. and Baylor College of Medicine have acquired a clearer view of the well-hidden mechanism involved. Their computer simulations may lead to new strategies to stop influenza, perhaps even a one-size-fits-all vaccine.

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