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Study documents MERS spread from camel to person

June 4, 2014 5:20 pm | by Mike Stobbe - AP Medical Writer - Associated Press | News | Comments

A new report offers the strongest evidence yet that a mysterious Middle East virus spreads from camels to people. Researchers studied the illness of a 44-year-old camel owner in Saudi Arabia, who died in November of Middle East respiratory syndrome, or MERS. Through repeated tests, they were able to show: the man and one camel were infected with the same virus.

Neural transplant reduces absence epilepsy seizures in mice

June 2, 2014 8:24 am | by Tracey Peake, North Carolina State Univ. | News | Comments

New research from North Carolina State Univ. pinpoints the areas of the cerebral cortex that are affected in mice with absence epilepsy and shows that transplanting embryonic neural cells into these areas can alleviate symptoms of the disease by reducing seizure activity. The work may help identify the areas of the human brain affected in absence epilepsy and lead to new therapies for sufferers.

A tool to better screen, treat aneurysm patients

May 30, 2014 8:26 am | by Anne M. Stark, Lawrence Livermore National Laboraotry | News | Comments

New research by an international consortium may help physicians better understand the chronological development of a brain aneurysm. Using radiocarbon dating to date samples of ruptured and unruptured cerebral aneurysm tissue, the team, led by neurosurgeon Nima Etminan, found that the main structural constituent and protein—collagen type I—in cerebral aneurysms is distinctly younger than once thought.

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A cure for dry eye could be a blink away

May 29, 2014 8:37 am | by Susan Gawlowicz, Rochester Institute of Technology | News | Comments

A treatment for dry eye, a burning, gritty condition that can impair vision and damage the cornea, could someday result from computer simulations that map the way tears move across the surface of the eye. To understand dry eye, the team had to begin with the physics and chemistry of tears.

Researchers target brain circuitry to treat intractable mental disorders

May 28, 2014 11:46 am | by Sarah Yang, Media Relations, UC Berkeley | Videos | Comments

Neuroscientists, engineers and physicians are teaming up for an ambitious five-year, $26 million project to develop new techniques for tackling mental illness. By using devices implanted in the brain, they aim to target and correct malfunctioning neural circuits in conditions such as clinical depression, addiction and anxiety disorders.

Sneaky bacteria change key protein’s shape to escape detection

May 28, 2014 10:23 am | News | Comments

Every once in a while in the U.S., bacterial meningitis seems to crop up out of nowhere, claiming a young life. Part of the disease’s danger is the ability of the bacteria to evade the body’s immune system, but scientists are now figuring out how the pathogen hides in plain sight. Their findings, which could help defeat these bacteria and others like it, appear in the Journal of the American Chemical Society.

“Nanodaisies” deliver drug cocktail to cancer cells

May 28, 2014 8:16 am | by Matt Shipman, News Services, North Carolina State Univ. | News | Comments

Biomedical engineering researchers have developed daisy-shaped, nanoscale structures that are made predominantly of anticancer drugs and are capable of introducing a “cocktail” of multiple drugs into cancer cells. The researchers are all part the joint biomedical engineering program at North Carolina State Univ. and the Univ. of North Carolina at Chapel Hill.

Researcher reboots deep brain stimulation

May 28, 2014 7:53 am | News | Comments

Deep brain stimulators, devices that zap Parkinson’s disease tremors by sending electrical current deep into nerve centers near the brain stem, may sound like they are cutting-edge, but Rice Univ.’s Caleb Kemere wants to give them a high-tech overhaul.

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Relaxation helps pack DNA into a virus

May 27, 2014 7:57 am | by Susan Brown, Univ. of California, San Diego | News | Comments

Taking a moment to pause and relax can help if you find yourself in a tight spot. This strategy can work for molecules as well as people, it turns out. Researchers at the Univ. of California, San Diego have found that DNA packs more easily into the tight confines of a virus when given a chance to relax.

Doctors design mini dialysis machine for babies

May 23, 2014 12:41 pm | by Maria Cheng, AP Medical Writer | News | Comments

Doctors in Italy have designed a miniature dialysis machine for babies, used for the first time last year to save a newborn girl. Usually, doctors adapt standard dialysis machines for babies, but that can be risky since the devices can't always be accurately tweaked. About 1 to 2% of hospitalized infants have kidney problems that may require dialysis, which cleans toxins from the blood when the kidneys aren't working.

Scrapbook-inspired diagnostics could curb hepatitis C pandemic

May 22, 2014 10:49 am | News | Comments

To the relief of patients diagnosed with hepatitis C, the U.S. Food and Drug Administration approved two new treatments late last year, and a few more are on the way. Now scientists are solving another side of the disease’s problem: identifying the millions more who have the virus but don’t know it—and unwittingly pass it on. A report in Analytical Chemistry describes a novel, scrapbook-inspired test that does just that.

Not just for the heart, red wine shows promise as cavity fighter

May 22, 2014 8:17 am | News | Comments

For anyone searching for another reason to enjoy a glass of red wine with dinner, here’s a good one: A new study has found that red wine, as well as grape seed extract, could potentially help prevent cavities. They say that their report, which appears in the Journal of Agricultural and Food Chemistry, could lead to the development of natural products that ward off dental diseases with fewer side effects.

Cognitive test can differentiate between Alzheimer’s and normal aging

May 21, 2014 8:06 am | by Chelsey Coombs, Life Sciences Intern, Univ. of Illinois, Urbana-Champaign | News | Comments

Researchers have developed a new cognitive test that can better determine whether memory impairments are due to very mild Alzheimer’s disease or the normal aging process. Previous research has shown that people with Alzheimer’s disease often have impairments in hippocampal function. So the team designed a task that tested participants’ relational memory abilities.

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Watching HIV bud from cells

May 19, 2014 8:09 am | by Lee J. Siegel, Science News Specialist, Univ. of Utah | Videos | Comments

Univ. of Utah researchers devised a way to watch newly forming AIDS virus particles emerging or “budding” from infected human cells without interfering with the process. The method shows a protein named ALIX gets involved during the final stages of virus replication, not earlier, as was believed previously.

Herpes-loaded stem cells used to kill brain tumors

May 16, 2014 2:09 pm | News | Comments

Harvard Stem Cell Institute scientists have a potential solution for how to more effectively kill tumor cells using cancer-killing viruses. The investigators report that trapping virus-loaded stem cells in a gel and applying them to tumors significantly improved survival in mice with glioblastoma multiforme, the most common brain tumor in human adults and also the most difficult to treat.

Fighting Ebola virus disease: Transformer protein provides new insights

May 16, 2014 8:25 am | by Manuel Gnida, SLAC National Accelerator Laboratory | News | Comments

A new study reveals that a protein of the Ebola virus can transform into three distinct shapes, each with a separate function that is critical to the virus’s survival. Each shape offers a potential target for developing drugs against Ebola virus disease, a hemorrhagic fever that kills up to nine out of 10 infected patients in outbreaks such as the current one in West Africa.

Extended-release medication offers promise for treating alcohol dependence

May 15, 2014 8:14 am | by David Stauth, Oregon State Univ. | News | Comments

A comparatively new form of a medication for alcohol and opioid dependence that’s injected once a month instead of taken orally once a day appears to be significantly more effective than some other medications—because more patients actually continue the prescribed regimen. The findings offer support for a wider use of medications that may help reduce or prevent substance abuse and related hospital admissions.

A new approach to treating peanut, food allergies

May 14, 2014 11:22 am | News | Comments

These days, more and more people seem to have food allergies, which can sometimes have life-threatening consequences. In the Journal of Agricultural and Food Chemistry, scientists report the development of a new type of flour that someday could be used in food-based therapies to help people better tolerate their allergy triggers, including peanuts.

The Bright Side of Fluorescence

May 14, 2014 8:49 am | by Takeharu Nagai, PhD, Osaka Univ., Japan | Photometrics | Articles | Comments

Fluorescent proteins have helped researchers open doors to countless molecular imaging applications and deepened our understanding of biological processes. Without fluorescence, advancements in oncology, drug discovery and any field that requires single-cell to whole-body imaging would be substantially limited.

Insight on HIV lifecycle gained through creative use of high-energy x-rays

May 14, 2014 7:59 am | by Tona Kunz, Argonne National Laboratory | News | Comments

A key step in the decades-long mystery of the HIV lifecycle was uncovered using what formerly was thought of as only a supplementary x-ray technique for structural biology. This advances study of HIV as well as highlights a powerful tool to obtain currently unobtainable high-resolution structural determination and characterization of RNA molecules.

Researchers identify extent of new tick-borne infection

May 8, 2014 11:32 am | by Michael Greenwood, Yale Univ. | News | Comments

The frequency of a new tick-borne infection that shares many similarities with Lyme disease, and a description of the antibody test used to test individuals for evidence of the infection, have been reported for the first time by researchers at the Yale Schools of Public Health and Medicine.

Experimental antibody shows early promise for treatment of childhood tumor

May 8, 2014 11:14 am | by The Associated Press | News | Comments

 Tumors shrank or disappeared and disease progression was temporarily halted in 15 children with advanced neuroblastoma enrolled in a safety study of an experimental antibody produced at St. Jude Children's Research Hospital. Four patients are still alive after more than two-and-a-half years and without additional treatment.

A lab in your pocket

May 8, 2014 8:33 am | by Marcia Goodrich, Michigan Technological Univ. | News | Comments

When you get sick, your physician may take a sample of your blood, send it to the laboratory and wait for results. In the near future, however, doctors may be able to run those tests almost instantly on a piece of plastic about the size of credit card. These labs-on-a-chip would not only be quick—results are available in minutes—but also inexpensive and portable.

Luminescent nanocrystal tags, high-speed scanner enable rapid detection of pathogens

May 7, 2014 7:42 am | by Elizabeth K. Gardner, Purdue Univ. | News | Comments

A research team using tunable luminescent nanocrystals as tags to advance medical and security imaging have successfully applied them to high-speed scanning technology and detected multiple viruses within minutes. The research builds on the team's earlier success in developing a way to control the length of time light from a luminescent nanocrystal lingers.

Soy sauce molecule may unlock drug therapy for HIV patients

May 6, 2014 7:49 am | News | Comments

For HIV patients being treated with anti-AIDS medications, resistance to drug therapy regimens is commonplace. Often, patients develop resistance to first-line drug therapies, such as Tenofovir, and are forced to adopt more potent medications. Virologists at the Univ. of Missouri now are testing the next generation of medications that stop HIV from spreading, and are using a molecule related to flavor enhancers found in soy sauce.

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