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Study: Psych drug ER trips approach 90,000 a year

July 9, 2014 6:23 pm | by Lindsey Tanner - AP Medical Writer - Associated Press | News | Comments

Bad reactions to psychiatric drugs result in nearly 90,000 emergency room visits each year by U.S. adults, with anti-anxiety medicines and sedatives among the most common culprits, a study suggests. A drug used in some popular sleeping pills was among the most commonly involved sedatives, especially in adults aged 65 and older.

Scientists uncover new compounds that could affect circadian rhythm

July 9, 2014 7:45 am | News | Comments

Scientists from The Scripps Research Institute have discovered a surprising new role for a pair of compounds—which have the potential to alter circadian rhythm, the complex physiological process that responds to a cycle of light and dark and is present in most living things. At least one of these compounds could be developed as a chemical probe to uncover new therapeutic approaches to a range of disorders, including diabetes and obesity.

Forgotten vials of smallpox found in storage room

July 8, 2014 12:29 pm | by Mike Stobbe, AP Medical Writer | News | Comments

Government officials say workers cleaning a storage room at National Institutes of Health in Maryland made a startling discovery last week. Decades-old vials of smallpox had been forgotten in a cardboard box. The only other known smallpox samples are in super-secure labs in the U.S. and Russia.

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Fine-scale climate model projections predict malaria at local levels

July 7, 2014 9:56 am | by Sara LaJeunesse, Penn State | News | Comments

According to a team of researchers who applied a statistical technique to conventional, coarse-scale climate models, population centers in cool, highland regions of East Africa could be more vulnerable to malaria than previously thought, while population centers in hot, lowland areas could be less vulnerable. The new approach improves the accuracy of earlier efforts that used global climate model simulations results.

Scientists find potential new use for cancer drug

June 27, 2014 7:19 am | News | Comments

Scientists working to make gene therapy a reality have solved a major hurdle: how to bypass a blood stem cell’s natural defenses and efficiently insert disease-fighting genes into the cell’s genome. In a new study, a team of researchers report that the drug rapamycin, which is commonly used to slow cancer growth, enables delivery of a therapeutic dose of genes to blood stem cells while preserving stem cell function.

People with tinnitus process emotions differently from peers

June 26, 2014 12:47 pm | by Chelsey Coombs, Life Sciences Intern, Univ. of Illinois, Urbana-Champaign | News | Comments

Patients with persistent ringing in the ears, a condition known as tinnitus, process emotions differently in the brain from those with normal hearing, researchers report in Brain Research. Tinnitus afflicts 50 million people in the U.S., and causes those with the condition to hear noises that aren’t really there. These phantom sounds are not speech, but rather whooshing noises, train whistles, cricket noises or whines.

FDA grapples with oversight of fecal transplants

June 26, 2014 12:18 pm | by Matthew Perrone - AP Health Writer - Associated Press | News | Comments

Imagine a low-cost treatment for a life-threatening infection that could cure up to 90% of patients with minimal side effects, often in a few days.It may sound like a miracle drug, but this cutting-edge treatment is profoundly simple—though somewhat icky: take the stool of healthy patients to cure those with hard-to-treat intestinal infections.

Panel: Flu spray better than shots for young kids

June 25, 2014 3:23 pm | by Mike Stobbe - AP Medical Writer - Associated Press | News | Comments

When it comes to flu vaccines, a federal panel says a squirt in the nose is better than a shot in the arm for young children. The advisory panel agreed Wednesday to tell doctors that FluMist nasal spray is a bit better at preventing flu in healthy young kids. The advice is specific to children ages 2 through 8.

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Researcher charged in major HIV vaccine fraud case

June 24, 2014 5:22 pm | by Ryan J. Foley - Associated Press - Associated Press | News | Comments

Responding to a major case of research misconduct, federal prosecutors are taking a rare step by charging a scientist with fraud after he admitted falsifying data while researching an HIV vaccine. Authorities say former Iowa State Univ. laboratory manager Dong-Pyou Han has confessed to manipulating data that helped his team get millions in grants and increased hopes of a major breakthrough in AIDS research.

FDA approves Cubist antibiotic for skin infections

June 20, 2014 7:21 pm | by Matthew Perrone - AP Health Writer - Associated Press | News | Comments

The Food and Drug Administration on Friday approved a new antibiotic from Cubist Pharmaceuticals to treat common skin infections often acquired in the hospital. Regulators cleared the company's Sivextro as a pill and as an intravenous solution for adults with skin infections caused by bacteria that are often resistant to older antibiotics.

New monkey model for AIDS offers promise for medical research

June 19, 2014 4:38 pm | by Zach Veilleux, The Rockefeller Univ. | News | Comments

HIV-1, the virus responsible for most cases of AIDS, is a very selective virus. It doesn’t readily infect species other than its usual hosts. While this would qualify as good news for most mammals, for humans this fact has made the search for effective treatments and vaccines for AIDS that much more difficult; without an accurate animal model of the disease, researchers have had few options for clinical studies of the virus.

How a new approach to funding Alzheimer’s research could pay off

June 19, 2014 10:46 am | by Peter Dizikes, MIT News Office | News | Comments

More than 5 million Americans suffer from Alzheimer’s disease, the affliction that erodes memory and other mental capacities, but no drugs targeting the disease have been approved by the U.S. Food and Drug Administration since 2003. Now a paper by an Massachusetts Institute of Technology professor suggests that a revamped way of financing Alzheimer’s research could spur the development of useful new drugs for the illness.

Asthma rates drop, but experts not breathing easier

June 19, 2014 12:21 am | by Mike Stobbe - AP Medical Writer - Associated Press | News | Comments

A new survey suggests asthma in the U.S. may finally be on the decline. But the results are so surprising that health officials are cautious about claiming a downturn. The findings come from a large national health survey conducted last year. The drop could just be an unexplained statistical blip.

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Feds seek ways to expand use of addiction drug

June 18, 2014 2:22 pm | by Matthew Perrone - AP Health Writer - Associated Press | News | Comments

The government's top drug abuse experts are struggling to find ways to expand use of a medicine widely considered the best therapy for treating heroin and painkiller addiction, but which remains underused. Senator Carl Levin of Michigan on Wednesday pressed government officials and agencies to increase access to the buprenorphine, a drug which helps addicts control drug cravings and withdrawal symptoms.

Findings point toward first therapy for Lou Gehrig’s disease

June 13, 2014 7:36 am | News | Comments

Researchers have determined that a copper compound known for decades may form the basis for a therapy for amyotrophic lateral sclerosis (ALS), or Lou Gehrig’s disease. In a new study, scientists showed in laboratory animal tests that oral intake of this compound significantly extended the lifespan and improved the locomotor function of transgenic mice that are genetically engineered to develop this debilitating and terminal disease.

Proliferation cues “natural killer” cells for job change

June 12, 2014 12:13 pm | by David Orenstein, Brown Univ. | News | Comments

Why would already abundant “natural killer” cells proliferate even further after subduing an infection? It’s been a biological mystery for 30 years. But now Brown Univ. scientists have an answer: After proliferation, the cells switch from marshaling the immune response to calming it down.

Brain retains signs of childhood trauma

June 12, 2014 11:20 am | by Bill Hathaway, Yale Univ. | News | Comments

People abused as children show reduced brain volume in regions governing emotion, learning and memory, deficits that make them more vulnerable to relapse—and relapses of greater severity—if they become substance abusers, a new study by Yale School of Medicine researchers shows. The studyidentifies potential biological markers that can identify addicts at high risk of relapse.

A key step toward a safer strep vaccine

June 12, 2014 8:17 am | News | Comments

An international team of scientists, led by researchers at the Univ. of California, San Diego School of Medicine, have identified the genes encoding a molecule that famously defines Group A Streptococcus (strep), a pathogenic bacterial species responsible for more than 700 million infections worldwide each year.

Increase in use of costly insulin analogs in type 2 diabetes

June 11, 2014 9:25 am | by Helen Dodson, Yale Univ. | News | Comments

There has been a dramatic increase in use of costly insulin analogs by type 2 diabetes patients, despite the lack of evidence that they are appreciably better than human synthetic insulin, according to Yale School of Medicine researchers. Further, overall insulin use by patients with type 2 diabetes (T2D) increased by 50% in the previous decade.

Study: Red meat possibly linked to breast cancer

June 11, 2014 9:22 am | by Maria Cheng - AP Medical Writer - Associated Press | News | Comments

Women who often indulge their cravings for hamburgers, steaks and other red meat may have a slightly higher risk of breast cancer, a new study suggests. Doctors have long warned that a diet loaded with red meat is linked to cancers including those of the colon and pancreas, but there has been less evidence for its role in breast cancer.

Inside the adult ADHD brain

June 11, 2014 8:49 am | by Anne Trafton, MIT News Office | News | Comments

About 11% of school-age children in the U.S. have been diagnosed with ADHD. While many eventually “outgrow” the disorder, some carry their difficulties into adulthood. In the first study to compare patterns of brain activity in adults who recovered from childhood ADHD and those who didn’t, neuroscientists have discovered key differences in a brain communication network that is active when the brain is at wakeful rest.

Obesity surgery may "cure" diabetes for 15 years

June 10, 2014 5:22 pm | by Lindsey Tanner - AP Medical Writer - Associated Press | News | Comments

Obesity surgery may keep diabetes in remission even after 15 years in some patients, a study suggests. Long-term results were missing for more than half the patients who began the study and remission rates dropped off considerably. But still, 35 out of 115 patients remained diabetes-free 15 years after surgery.

Report: Diabetes numbers continue to rise in U.S.

June 10, 2014 11:26 am | by Mike Stobbe - AP Medical Writer - Associated Press | News | Comments

The number of Americans with diabetes has increased again—now more than 29 million people have the illness. That's an increase of about 3 million from three years ago. In new report released Tuesday, federal scientists calculated that more than 9% of Americans have diabetes—or one in 11people.

Engineers develop mobile DNA test for HIV

June 6, 2014 7:31 am | by Mike Williams, Rice Univ. | News | Comments

Rice Univ. bioengineers are developing a simple, highly accurate test to detect signs of HIV and its progress in patients in resource-poor settings. The current gold standard to diagnose HIV in infants and to monitor viral load depends on laboratory equipment and technical expertise generally available only in clinics. The new research features a nucleic acid-based test that can be performed at the site of care.

One and done: Antibiotic could provide single-dose option

June 5, 2014 8:20 am | by Duke Medicine News and Communications | News | Comments

In the battle against stubborn skin infections, including methicillin-resistant Staphylococcus aureus (MRSA), a new single-dose antibiotic is as effective as a twice-daily infusion given for up to 10 days, according to a large study led by Duke Medicine researchers. Researchers said the advantage of the new drug, oritavancin, is its potential to curtail what has been a key driver of antibiotic resistance.

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