Diagnostics
New instrument will quickly detect biothreat agents
April 2, 2013 8:04 am | News | Comments
Researchers at Sandia National Laboratories are developing a medical instrument that will be able to quickly detect a suite of biothreat agents, including anthrax, ricin, botulinum, shiga, and SEB toxin. The device, once developed, approved by the U.S. Food and Drug Administration, and commercialized, would most likely be used in emergency rooms in the event of a bioterrorism incident.
Tests on cancer cells shows them as “squishy”, yet tactically strong
April 29, 2013 8:06 am | News | Comments
To get a better understanding of metastasis, more than 95 graduate students, post docs...
Study aims to understand how neurons represent the world
April 23, 2013 11:49 am | News | Comments
To understand the development of sensory representations within our brain, we have to...
Lost your keys? Your cat? The brain can rapidly mobilize a search party
April 22, 2013 9:46 am | News | Comments
Scientists at the University of California, Berkeley, have discovered that when we...
Device can extract human DNA with full genetic data in minutes
May 6, 2013 1:15 pm | News | CommentsTake a swab of saliva from your mouth and within minutes your DNA could be ready for analysis and genome sequencing with the help of a new device. University of Washington engineers and NanoFacture, a Bellevue, Wash., company, have created a device that can extract human DNA from fluid samples in a simpler, more efficient, and environmentally friendly way than conventional methods.
Physical by smartphone becoming real possibility
May 2, 2013 3:35 am | by LAURAN NEERGAARD - AP Medical Writer - Associated Press | News | CommentsIt's not a "Star Trek" tricorder, but by hooking a variety of gadgets onto a smartphone you could almost get a complete physical—without the paper gown or even a visit to the doctor's office. Blood pressure? Just plug the arm cuff into the phone for a quick reading. Heart okay? Put your fingers in the right spot, and the squiggly rhythm of an EKG appears on the phone's screen.
Bad decisions arise from faulty information, not faulty brain circuits
April 16, 2013 8:11 am | News | CommentsMaking choices involves the evaluation of an accumulation of facts. If a wrong choice is made, Princeton University researchers have recently found, the problem may lie in the facts, or information, rather than the brain's decision-making process. The researchers report that erroneous decisions tend to arise from errors, or "noise," in the information coming into the brain.
Implanted 'bracelet' helps treat chronic heartburn
April 11, 2013 10:31 am | by MARILYNN MARCHIONE - AP Chief Medical Writer - Associated Press | News | CommentsA tiny magnetic bracelet implanted at the base of the throat is greatly improving life for some people with chronic heartburn who get limited relief from medicines. It's a novel way to treat severe acid reflux, which plagues millions of Americans and can raise their risk for more serious health problems.
Doctors use brain scans to “see” and measure pain
April 11, 2013 3:24 am | by Marilynn Marchione, AP Chief Medical Writer | News | CommentsIn a provocative new study, scientists reported Wednesday that they were able to "see" pain on brain scans and, for the first time, measure its intensity and tell whether a drug was relieving it. Though the research is in its early stages, it opens the door to a host of possibilities. For example, scans might be used someday to tell when pain is hurting a baby, someone with dementia, or a paralyzed person unable to talk.
ORNL's awake imaging device moves diagnostics field forward
April 4, 2013 12:13 pm | News | CommentsA technology being developed at Oak Ridge National Laboratory promises to provide clear images of the brains of children, the elderly, and people with Parkinson's and other diseases without the use of uncomfortable or intrusive restraints. Awake imaging provides motion compensation reconstruction, which removes blur caused by motion, allowing physicians to get a transparent picture of the functioning brain without anesthetics that can mask conditions and alter test results.
New system to improve DNA sequencing
April 3, 2013 9:11 am | News | CommentsA sensing system developed at the University of Cambridge is being commercialized in the U.K. for use in rapid, low-cost DNA sequencing, which would make the prediction and diagnosis of disease more efficient, and individualized treatment more affordable.
MicroRNA detection on the cheap
March 29, 2013 7:37 am | by Rob Matheson, MIT News Office | News | CommentsCurrent methods of detecting microRNA (miRNA) can be time consuming and costly: The custom equipment used in such tests costs more than $100,000, and the limited throughput of these systems further hinders progress. Two Massachusetts Institute of Technology alumni are helping to rectify these issues through their fast-growing, Cambridge-headquartered startup, Firefly BioWorks Inc., which provides technology that allows for rapid miRNA detection in a large number of samples using standard laboratory equipment.
DNA test identifies ingredients in foods
March 27, 2013 9:18 am | News | CommentsAlmost all foodstuffs contain the genetic material of those animal and plant species that were used in their preparation. Scientists at Johannes Gutenberg University Mainz have developed a novel screening procedure that provides for highly sensitive, quantifiable analysis of animal, plant, and microbial substances present in foodstuffs. For this, the researchers have adapted the latest techniques of DNA sequencing.
Counting white blood cells at home
March 26, 2013 9:59 am | News | CommentsCurrently, most white blood cell counts are performed with large-scale equipment in central clinical laboratories. If a physician collects blood samples from a patient in the office, it can take days to get the results. But now engineers at the California Institute of Technology, working with LeukoDx, have developed a portable device to count white blood cells that needs less than a pinprick's worth of blood and takes just minutes to run.
Wireless, implanted sensor broadens range of brain research
March 19, 2013 3:31 pm | News | CommentsA compact, self-contained sensor recorded and transmitted brain activity data wirelessly for more than a year in early stage animal tests, according to a recent study funded by the National Institutes of Health. In addition to allowing for more natural studies of brain activity in moving subjects, this implantable device represents a potential major step toward cord-free control of advanced prosthetics that move with the power of thought
Rapid cancer detection built on a chip
March 8, 2013 3:39 pm | News | CommentsEarly detection is vital for the effective treatment of cancer. In many cases, tell-tale biomarkers are present in the bloodstream long before outward symptoms become apparent. The development of an inexpensive and rapid point-of-care diagnostic test capable of spotting such early biomarkers of disease could save many lives. A research team in Japan working on developing such a test has now produced their most sensitive microRNA detector yet.
New tool better estimates pandemic threats
March 6, 2013 11:12 am | News | CommentsA simple new method better assesses the risks posed by emerging zoonotic viruses Researchers show that the new tool can produce transmissibility estimates for swine flu, allowing researchers to better evaluate the possible pandemic threat posed by this virus. ntil now, estimates of transmissibility were derived from detailed outbreak investigations, which are resource intensive and subject to selection bias.
Diagnostic cocktail: Pour, shake and stir
March 1, 2013 10:01 am | News | CommentsA homebrewed diagnostic mixture containing a single drop of blood, a dribble of water, and a dose of DNA powder with gold particles could mean rapid diagnosis and treatment of the world's leading diseases in the near future. The cocktail diagnostic is being developed at the University of Toronto and it involves the same technology used in over-the-counter pregnancy tests.
Disease diagnosis at the touch of a button
February 26, 2013 7:56 am | News | CommentsWhen viruses like HIV/AIDS strike in underdeveloped regions of the world, they often spiral out of control in part because there is no easy way to bring diagnostic equipment to remote areas so that the diseases can be identified, treated, and stopped before they spread. Now, an inexpensive, portable, easy-to-use device, built by a team of Caltech engineers and biologists, promises to speed the diagnosis of HIV/AIDS and other diseases—and improve treatment—in even the most far-flung corners of the world.
Why cells stick: Phenomenon extends longevity of bonds between cells
February 15, 2013 8:50 am | News | CommentsResearch carried out by scientists at the Georgia Institute of Technology and The University of Manchester has revealed new insights into how cells stick to each other and to other bodily structures, an essential function in the formation of tissue structures and organs. It's thought that abnormalities in their ability to do so play an important role in a broad range of disorders, including cardiovascular disease and cancer.
Building a biochemistry lab-on-a-chip
February 13, 2013 8:04 am | News | CommentsMiniaturized laboratory-on-chip systems promise rapid, sensitive, and multiplexed detection of biological samples for medical diagnostics, drug discovery, and high-throughput screening. Using microfabrication techniques and incorporating a unique design of transistor-based heating, researchers at the University of Illinois at Urbana-Champaign are further advancing the use of silicon transistor and electronics into chemistry and biology for point-of-care diagnostics.
Scientists probe human cells with high-frequency sound
February 4, 2013 8:29 am | News | CommentsSound waves are widely used in medical imaging, such as when doctors take an ultrasound of a developing fetus. Now scientists have developed a way to use sound to probe tissue on a much tinier scale. Researchers deployed high-frequency sound waves to test the stiffness and viscosity of the nuclei of individual human cells. The probe could eventually help answer questions such as how cells adhere to medical implants and why healthy cells turn cancerous.
Breath test identifies bacteria's fingerprint
January 14, 2013 11:51 am | News | CommentsScientists have identified the chemical "fingerprints" given off by specific bacteria when present in the lungs, potentially allowing for a quick and simple breath test to diagnose infections such as tuberculosis. The researchers have successfully distinguished between different types of bacteria, as well as different strains of the same bacteria, in the lungs of mice by analyzing the volatile organic compounds (VOCs) present in exhaled breath.
Improving the accuracy of cancer diagnoses
December 26, 2012 8:41 am | by Anne Trafton, MIT News Office | News | CommentsTiny calcium deposits can be a telltale sign of breast cancer. However, in the majority of cases these microcalcifications signal a benign condition. A new diagnostic procedure developed at Massachusetts Institute of Technology and Case Western Reserve University could help doctors more accurately distinguish between cancerous and noncancerous cases.
Glowing fish shed light on metabolism
December 3, 2012 11:48 am | News | CommentsEmerging from a panel of 2,400 medications and drug-like compounds tested in a tiny zebrafish, a compound has been pinpointed by researchers who say it regulates whole-body metabolism and appears to protect obese mice from signs of metabolic disorders. The discovery may help drug discovery efforts to help help the rising population of Americans adults at risk for diabetes and other metabolic disorders.
White smell: Scientists find odor has color
November 26, 2012 4:49 pm | News | CommentsYou can see the color white; you can hear white noise. Now, researchers have shown that you can also smell a white odor. To be perceived as white, a stimulus (like light or sound) must meet two conditions: The mix that produces them must span the range of our perception; and each component must be present at the exact same intensity. Neuroscientists have reproduced these conditions for scent.
Tooth “tattoo” sensor may help dentists assess patients' oral health
November 9, 2012 8:58 am | by David Levin, Tufts University | News | CommentsA sensor invented by Tufts University bioengineers, when attached temporarily to a tooth, could one day help dentists fine-tune treatments for patients with chronic periodontitis, for example, or even provide a window on a patient’s overall health. The thin foil-like sensor is built from gold, silk, and graphite, has a built-in antenna to receive power and signals, and is applied directly to a tooth.
Portable device enables quick RNA detection
November 8, 2012 10:29 am | News | CommentsA new power-free microfluidic chip developed by researchers at the RIKEN Advanced Science Institute enables detection of microRNA from extremely small sample volume in only 20 minutes. By drastically reducing the time and quantity of sample required for detection, the chip lays the groundwork for early-stage point-of-care diagnosis of diseases.
Children’s hospital, Silicon Valley to market medical research software
October 31, 2012 10:18 pm | News | CommentsThe latest significant biomedical informatics technology is not coming from the biotech industry or a university. In fact, it’s coming from a children’s hospital. Nationwide Children’s Hospital in Columbus, Ohio, and Transformatix Technologies, Inc., in Davis, California, have partnered to create BioLinQ, a new biomedical informatics company designed to supply advanced software solutions for disease diagnosis and medical research.
