The condition of an athlete's heart has for the first time been accurately monitored throughout the duration of a marathon race. The real-time monitoring was achieved by continuous electrocardiogram (ECG) surveillance and data transfer over a public mobile phone network. The new development allows instantaneous diagnosis of potentially fatal rhythm disorders.
Cancer researchers have found that a simple blood test might help diagnose pancreatic cancer, one of the most deadly forms of the disease. In new research at Indiana Univ., scientists have found that several microRNAs, which are small RNA molecules, circulate at high levels in the blood of pancreatic cancer patients.
Starting Monday, millions of people who have avoided colon cancer screening can get a new home test that's noninvasive and doesn't require the icky preparation most other methods do. The test is the first to look for cancer-related DNA in stool. But deciding whether to get it is a more complex choice than ads for "the breakthrough test ... that's as easy as going to the bathroom" make it seem.
New achievements in synthetic biology, which will allow complex cellular recognition reactions to proceed outside of living cells, will dare scientists to dream big: There could one day be inexpensive, shippable and accurate test kits that use saliva or a drop of blood to identify specific disease or infection.
Researchers at the Univ. of Pennsylvania and The Children's Hospital of Philadelphia have used graphene to fabricate a new type of microelectrode that solves a major problem for investigators looking to understand the intricate circuitry of the brain. The see-through, one-atom-thick electrodes can obtain both high-resolution optical images and electrophysiological data for the first time.
Scientists have been laboring to detect cancer and a host of other diseases in people using promising new biomarkers called “exosomes.” Indeed, Popular Science magazine named exosome-based cancer diagnostics one of the 20 breakthroughs that will shape the world this year. Exosomes could lead to less invasive, earlier detection of cancer, and sharply boost patients’ odds of survival.
A U.S.-British scientist and a Norwegian husband-and-wife research team won the Nobel Prize in medicine for discovering the brain's navigation system—the inner GPS that helps us find our way in the world—a revelation that could lead to advances in diagnosing Alzheimer's. The research by John O'Keefe, May-Britt Moser and Edvard Moser represents a "paradigm shift" in neuroscience that could help researchers understand Alzheimer's disease.
Life Science researchers have become ever-more dependent on the industry for “kits” that are intended to execute research processes in the laboratory flawlessly. In recognition of this expectation, kit manufacturers now market nearly every product as “guaranteed” or “validated.” This practice has led the research community to feel secure that the products will perform as advertised.
Massachusetts Institute of Technology engineers have devised a way to rapidly test hundreds of different drug-delivery vehicles in living animals, making it easier to discover promising new ways to deliver a class of drugs called biologics, which includes antibodies, peptides, RNA and DNA, to human patients.
Almost all of today’s previously existing cell-sorting methods rely on what is called a single-cell analysis platform. A researcher in Hawaii took a different approach, inventing a bulk method that sorts different cell populations by tuning their solubility. Instead of targeting individual features, the measurement principle sorts cells by differentiating their characteristic surface free energies.
A new, ultrasensitive biosensor made from graphene has been used to detect molecules that indicate an increased risk of developing cancer. The biosensor has been shown to be more than five times more sensitive than bioassay tests currently in use, and was able to provide results in a matter of minutes, opening up the possibility of a rapid, point-of-care diagnostic tool for patients.
Fewer than half of all patients who are suspected of having a genetic disease actually receive a satisfactory diagnosis. To solve this problem, scientists have developed an innovative diagnostic procedure, called PhenIX, that combines the analysis of genetic irregularities with the patient's clinical presentation. The method involves a search for genes that cause disease and its related phenotypes to produce a short, testable list.
Things can go downhill fast when a patient has sepsis, a life-threatening condition in which bacteria or fungi multiply in a patient's blood—often too fast for antibiotics to help. A new device inspired by the human spleen and developed by a team at Harvard's Wyss Institute for Biologically Inspired Engineering may radically transform the way doctors treat sepsis.
A simple point-of-care testing device for anemia could provide more rapid diagnosis of the common blood disorder and allow inexpensive at-home self-monitoring of persons with chronic forms of the disease. The disposable self-testing device analyzes a single droplet of blood using a chemical reagent that produces visible color changes corresponding to different levels of anemia.
New research in Europe suggests that testing the temperature of breath could be a simple and noninvasive method to either confirm or reject the presence of lung cancer. Many research teams have been looking at the possibility of using breath tests for a number of cancers but this is the first study looking at breath temperature as a marker in lung cancer.
A new atomically thin 2-D ultrasensitive semiconductor material developed by researchers California promises to push the boundaries of biosensing technology toward single-molecule detection. Based on molybdenum disulfide or molybdenite, the biosensor material which is used commonly as a dry lubricant, surpasses graphene’s already high sensitivity, offers better scalability and lends itself to high-volume manufacturing.
Over the past several decades, malaria diagnosis has changed very little. After taking a blood sample from a patient, a technician smears the blood across a glass slide, stains it with a special dye and looks under a microscope for the Plasmodium parasite, which causes the disease. This approach gives an accurate count of how many parasites are in the blood, but is not ideal because there is potential for human error.
DARPA’s new Electrical Prescriptions (ElectRx) program was among the initiatives the White House highlighted this week as President Barack Obama addressed the need for new and more effective strategies for improving the health of service members, veterans and others. ElectRx goes beyond medication, aiming to explore neuromodulation of organ functions to help the human body heal itself.
For the 2.2 million Americans battling glaucoma, the main course of action for staving off blindness involves weekly visits to eye specialists who monitor increasing pressure within the eye. Now researchers have developed an eye implant that could help stave off blindness caused by glaucoma. The tiny eye implant developed at Stanford Univ. could enable patients to take more frequent readings from the comfort of home.
Univ. of Illinois engineers are bringing a touch of color to glucose monitoring. The researchers developed a new continuous glucose monitoring material that changes color as glucose levels fluctuate, and the wavelength shift is so precise that doctors and patients may be able to use it for automatic insulin dosing—something now possible using current point measurements like test strips.
Researchers have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel. Their device, about the size of a dime, could be used to detect the extremely rare tumor cells that circulate in cancer patients’ blood, helping doctors predict whether a tumor is going to spread.
David Erickson, a professor at Cornell Univ., will receive a $3 million National Science Foundation grant over five years to adapt smartphones for health monitoring. The program, dubbed PHeNoM for Public Health, Nanotechnology, and Mobility, aims to deploy three systems that can have an immediate impact on personal healthcare.
To mitigate anthrax attack risks, Sandia National Laboratories developed a credit-card sized device based on the lateral flow assay for detection of B. anthracis in ultra-low resource environments: BaDx (Bacillus anthracis diagnostics). BaDx is a low-cost, disposable device that requires no power, instrumentation or equipment to operate, and no refrigeration to maintain efficacy.
Novilytic’s Noviplex Plasma Collection Card is a self-contained, blood-plasma sampling device used to volumetrically collect a plasma aliquot independent of whole blood application volumes. The Noviplex requires no power and circumvents requirements for venipuncture-phlebotomy training, needles, special vials and equipment, refrigeration and centrifugation normally associated with traditional plasma methods.
Previous research into the health impacts of in utero exposure to the 9/11 dust cloud on birth outcomes has shown little evidence of consistent effects. But according to a new paper pregnant women living near the World Trade Center during 9/11 experienced higher-than-normal negative birth outcomes. These mothers were more likely to give birth prematurely and deliver babies with low birth weights.