Things can go downhill fast when a patient has sepsis, a life-threatening condition in which bacteria or fungi multiply in a patient's blood—often too fast for antibiotics to help. A new device inspired by the human spleen and developed by a team at Harvard's Wyss Institute for Biologically Inspired Engineering may radically transform the way doctors treat sepsis.
A simple point-of-care testing device for anemia could provide more rapid diagnosis of the...
A new atomically thin 2-D ultrasensitive...
Over the past several decades, malaria diagnosis has changed very little. After taking a blood sample from a patient, a technician smears the blood across a glass slide, stains it with a special dye and looks under a microscope for the Plasmodium parasite, which causes the disease. This approach gives an accurate count of how many parasites are in the blood, but is not ideal because there is potential for human error.
DARPA’s new Electrical Prescriptions (ElectRx) program was among the initiatives the White House highlighted this week as President Barack Obama addressed the need for new and more effective strategies for improving the health of service members, veterans and others. ElectRx goes beyond medication, aiming to explore neuromodulation of organ functions to help the human body heal itself.
For the 2.2 million Americans battling glaucoma, the main course of action for staving off blindness involves weekly visits to eye specialists who monitor increasing pressure within the eye. Now researchers have developed an eye implant that could help stave off blindness caused by glaucoma. The tiny eye implant developed at Stanford Univ. could enable patients to take more frequent readings from the comfort of home.
Univ. of Illinois engineers are bringing a touch of color to glucose monitoring. The researchers developed a new continuous glucose monitoring material that changes color as glucose levels fluctuate, and the wavelength shift is so precise that doctors and patients may be able to use it for automatic insulin dosing—something now possible using current point measurements like test strips.
Researchers have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel. Their device, about the size of a dime, could be used to detect the extremely rare tumor cells that circulate in cancer patients’ blood, helping doctors predict whether a tumor is going to spread.
David Erickson, a professor at Cornell Univ., will receive a $3 million National Science Foundation grant over five years to adapt smartphones for health monitoring. The program, dubbed PHeNoM for Public Health, Nanotechnology, and Mobility, aims to deploy three systems that can have an immediate impact on personal healthcare.
To mitigate anthrax attack risks, Sandia National Laboratories developed a credit-card sized device based on the lateral flow assay for detection of B. anthracis in ultra-low resource environments: BaDx (Bacillus anthracis diagnostics). BaDx is a low-cost, disposable device that requires no power, instrumentation or equipment to operate, and no refrigeration to maintain efficacy.
Novilytic’s Noviplex Plasma Collection Card is a self-contained, blood-plasma sampling device used to volumetrically collect a plasma aliquot independent of whole blood application volumes. The Noviplex requires no power and circumvents requirements for venipuncture-phlebotomy training, needles, special vials and equipment, refrigeration and centrifugation normally associated with traditional plasma methods.
Previous research into the health impacts of in utero exposure to the 9/11 dust cloud on birth outcomes has shown little evidence of consistent effects. But according to a new paper pregnant women living near the World Trade Center during 9/11 experienced higher-than-normal negative birth outcomes. These mothers were more likely to give birth prematurely and deliver babies with low birth weights.
In the future, working up a sweat by exercising may not only be good for your health, but it could also power your small electronic devices. Researchers report that they have designed a sensor in the form of a temporary tattoo that can both monitor a person’s progress during exercise and produce power from their perspiration.
The Food and Drug Administration has approved the first screening test for colon cancer that uses patient DNA to help spot potentially deadly tumors and growths. The Cologuard test from Exact Sciences detects irregular mutations in a patient's stool sample that can be an early warning sign of cancer. Patients who test positive for the mutations should undergo a colonoscopy to confirm the results.
Melanoma is the fifth most common cancer type in the United States. A new handheld device may help diagnosis and treatment efforts for the disease. It uses lasers and sound waves and is the first that can be used directly on a patient to accurately measure how deep a melanoma tumor extends into the skin.
The Wyss Institute for Biologically Inspired Engineering at Harvard Univ. announced that its human “Organs-on-Chips” technology will be commercialized by a newly formed private company to accelerate development of pharmaceutical, chemical, cosmetic and personalized medicine products.
Janelia Research Campus experts have built a new computational method that can essentially automate much of the time-consuming process of reconstructing an animal's developmental building plan cell by cell. Using image data obtaining using a sophisticated form of light sheet microscopy, the tool can track the movement of cells in an animal’s body in 3-D.
HIV-infected people carry many different HIV viruses and all have distinct personalities—some much more vengeful and infectious than others. Yet, despite the breadth of infectivity, roughly 76% of HIV infections arise from a single virus. Now, scientists believe they can identify the culprit with very specific measurements of the quantities of a key protein in the HIV virus.
The rate of HIV infections diagnosed in the U.S. each year fell by one-third over the past decade, a government study finds. Experts celebrated it as hopeful news that the AIDS epidemic may be slowing in the U.S. The reasons for the drop aren't clear. It might mean fewer new infections are occurring. Or that most infected people already have been diagnosed so more testing won't necessarily find many more cases.
Most current methods of identifying intracellular information result in the death of the individual cells, making it impossible to continue to gain information and assess change over time. Using magnetized carbon nanotubes, scientists in Texas have devised a new method for extracting molecules from live cells without disrupting cell development.
Popping the blisters on the bubble wrap might be the most enjoyable thing about moving. But now, researchers led by 2007 R&D Magazine Scientist of the Year George Whitesides propose a more productive way to reuse the popular packing material: as a sheet of small, test tube-like containers for medical and environmental samples. Analyses can take place right in the bubbles.
A cheap, portable, microchip-based test for diagnosing type-1 diabetes could speed up diagnosis and enable studies of how the disease develops. Handheld microchips distinguish between the two main forms of diabetes mellitus, which are both characterized by high blood-sugar levels but have different causes. Until now, making the distinction has required a slow, expensive test available only in sophisticated healthcare settings.
In a basement laboratory at Fort Sam Houston military base in Texas, a research team has spent the last two years simulating improvised explosive device blasts on postmortem pig eyes using a high-powered shock tube. Their most striking discovery is that these blasts can damage the optic nerve, and these injuries can occur even at low pressures, causing visual defects that until now have been associated traumatic brain injuries.
Researchers compare the processing of biological fluid samples with searching for a needle in a haystack—only in this case, the haystack could be diagnostic samples, and the needle might be tumor cells present in just ppm concentrations. Now, a new way of processing these samples could make such detections possible in real time.
Lung cancer causes more deaths in the U.S. than the next three most common cancers combined, and the main reason is poor detection methods. A new device developed by a team of Israeli, American and British cancer researchers may turn the tide by both accurately detecting lung cancer and identifying its stage of progression. The breathalyzer test is embedded with a "NaNose" nanotech chip to literally "sniff out" cancer tumors.
A biological detection technology developed by Lawrence Livermore National Laboratory scientists can detect bacterial pathogens in the wounds of U.S. soldiers that have previously been missed by other technologies. This advance may, in time, allow an improvement in how soldiers' wounds are treated.
A bold new way to test cancer drugs started Monday. Like a medical version of speed dating, doctors will sort through multiple experimental drugs and match patients to the one most likely to succeed based on each person's unique tumor gene profile. Five drug companies, the government, private foundations and advocacy groups are taking part.
A large team of scientists have developed a “nanobarrel” molecular container that traps and concentrates light onto single molecule. These nanobarrels, which act as tiny test tubes, have been combined with gold nanoparticles so that researchers can detect what is in each one. The invention could be used as a low-cost and reliable diagnostic test.
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