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WHO: Small cancer risk after Fukushima accident

February 28, 2013 10:22 am | by MARIA CHENG - AP Medical Writer - Associated Press | News | Comments

People exposed to the highest doses of radiation during Japan's Fukushima nuclear plant disaster in 2011 may have a slightly higher risk of cancer but one so small it probably won't be detectable, the World Health Organization said in a report released Thursday.

Chemists find help from nature in fighting cancer

February 27, 2013 7:52 am | by Anne Trafton, MIT News Office | News | Comments

Inspired by a chemical that fungi secrete to defend their territory, Massachusetts Institute of Technology chemists have synthesized and tested several dozen compounds that may hold promise as potential cancer drugs.

One-two punch strategy against bacteria, cancer

February 11, 2013 4:44 pm | News | Comments

Cancer researchers from Rice University suggest that a new man-made drug that’s already proven effective at killing cancer and drug-resistant bacteria could best deliver its knockout blow when used in combination with drugs made from naturally occurring toxins.


Nanoscale vehicle battles cancer

February 6, 2013 3:38 pm | News | Comments

A tiny capsule invented at a University of California, Los Angeles laboratory could go a long way toward improving cancer treatment. Devising a method for more precise and less invasive treatment of cancer tumors, the team has developed a degradable nanoscale shell to carry proteins to cancer cells and stunt the growth of tumors without damaging healthy cells.

Scientists build harness for powerful radiation cancer therapy

February 5, 2013 8:24 am | News | Comments

Low-energy radiation particles, known as beta particles, are often used in radiation treatments for cancer patients. For years, scientists have been studying how to use alpha particles, which are far higher in energy, for the same treatments. The challenge has been finding ways to focus these powerful particles on target cancers without hurting other tissues. A collaboration of scientists have recently created a gold nanoparticle that can transport powerful alpha particles directly to tumors for treatment.

Improving the accuracy of cancer diagnoses

December 26, 2012 8:41 am | by Anne Trafton, MIT News Office | News | Comments

Tiny calcium deposits can be a telltale sign of breast cancer. However, in the majority of cases these microcalcifications signal a benign condition. A new diagnostic procedure developed at Massachusetts Institute of Technology and Case Western Reserve University could help doctors more accurately distinguish between cancerous and noncancerous cases.

PNNL recognized for transferring innovations to the marketplace

December 21, 2012 9:21 am | News | Comments

The Federal Laboratory Consortium announced this week that the Department of Energy national laboratory in Richland is receiving three 2013 Excellence in Technology Transfer awards in recognition for creating technologies or processes that can store large amounts of renewable energy until it's needed, fight cancer and detect explosives, and then moving the innovations to the marketplace.

Spread of cancer cells may be slowed by targeting of protein

December 18, 2012 11:39 am | News | Comments

The spread of cancer cells may be slowed by targeting the protein km23-1, according to researchers at Penn State University College of Medicine. A motor protein that transports cargo within the cell, km23-1 is also involved in the movement or migration of cells. Migration is necessary for cancer to spread, so understanding this cell movement is important for development of better cancer treatments.


Scientists capture, preserve cancer cells circulating in blood

December 17, 2012 3:11 pm | News | Comments

Researchers in Japan and California have built a nanoscale Velcro-like device that captures and releases tumor cells that have broken away from primary tumors and are circulating in the bloodstream. This new nanotechnology could be used for cancer diagnosis and give insight into the mechanisms of how cancer spreads throughout the body.

Controlled Success

December 14, 2012 11:42 am | by Paul Livingstone | Articles | Comments

From an early age, the 2012 Scientist of the Year knew that his knowledge of chemistry could make a difference in medicine. He’s still exploring just how much impact that can be.

Protein strongest just before death

December 12, 2012 4:35 pm | News | Comments

Retinoblastoma protein are tumor suppressors that can be dysfunctional in several major types of cancers. Researchers at Michigan State University have discovered that these proteins actually do their best work with one foot in the grave. Most proteins, like living things, become weaker toward the end of their lifecycle. Retinoblastoma proteins instead become stronger.

Capturing circulating cancer cells provides insights into how disease spreads

December 12, 2012 10:48 am | News | Comments

A glass plate with a nanoscale roughness could be a simple way for scientists to capture and study the circulating tumor cells that carry cancer around the body through the bloodstream. Engineering and medical researchers at the University of Michigan have devised such a set-up, which they say takes advantage of cancer cells' stronger drive to settle and bind compared with normal blood cells.

DNA self-assembly enables “drag-and-drop” drug development

December 6, 2012 12:52 pm | News | Comments

Using a simple "drag-and-drop" computer interface and DNA self-assembly techniques, researchers with Parabon NanoLabs of Reston, Va.,have developed a new approach for drug development that could drastically reduce the time required to create and test medications. Parabon has partnered with Janssen Research & Development to use this technology to create and test the efficacy of a new prostate cancer drug.


The nanomechanical signature of breast cancer

October 22, 2012 9:16 am | News | Comments

The spread of cancer cells from primary tumors to other parts of the body remains the leading cause of cancer-related deaths. Using atomic force microscopy, a research group in Europe has recently shown how the unique nanomechanical properties of breast cancer cells are fundamental to the process of metastasis.

Complex logic circuits can be made from bacterial genes

October 12, 2012 5:07 pm | by Diana Lutz, Washington University in St. Louis, Tae Seok Moon, logic circuit, gene circuit | News | Comments

Logic circuits can be built from just about anything, including billiard balls, pipes of water, or animals in a maze. Tae Seok Moon, a professor at Washington University in St. Louis, intends to build logic gates out of genes, and has already built the largest such device yet reported. But the purpose of these circuits is not to crunch numbers.

Scientists discover that shape matters in DNA nanoparticle therapy

October 12, 2012 10:03 am | News | Comments

Researchers from Johns Hopkins and Northwestern universities have discovered how to control the shape of nanoparticles that move DNA through the body and have shown that the shapes of these carriers may make a big difference in how well they work in treating cancer and other diseases. The technique is noteworthy because it does not use a virus to carry DNA into cells.

Nanoscale drug discovery approach relies on in silico, in vivo, in vitro

October 10, 2012 10:58 am | News | Comments

Using in silico computational tools to complement the results of in vivo and in vitro experiments, researchers at Pacific Northwest National Laboratory have revealed an atomic-level understanding of the mechanism by which nanoparticles inhibit the growth and metastasis of pancreatic tumors. The findings are promising for the development of particle-based therapies.

Optimized substance forces cancer cells into death

October 2, 2012 3:47 am | News | Comments

Many tumor cells have a defective cellular equipment. It is only by a special trick that they manage to distribute their chromosomes correctly to their daughter cells during cell division. Researchers have now developed a substance that thwarts this trick and forces cancer cells into death during cell division.

zarre tumor case may lead to custom cancer care

October 1, 2012 5:01 am | by Marilynn Marchone, AP Chief Medical Writer | News | Comments

It's a medical nightmare: a 24-year-old man endures 350 surgeries since childhood to remove growths that keep coming back in his throat and have spread to his lungs, threatening his life. A new discovery, however, allows doctors to grow "mini tumors" from each patient's cancer in a lab dish, then test various drugs or combinations on them to see which works best.

Bizarre tumor case may lead to custom cancer care

September 26, 2012 1:40 pm | by Marilynne Marchione, AP Chief Medical Writer - Associated Press | News | Comments

It's a medical nightmare: a 24-year-old man endures 350 surgeries since childhood to remove growths that keep coming back in his throat and have spread to his lungs, threatening his life. Now doctors have found a way to help him by way of a scientific coup that holds promise for millions of cancer...

Exposing cancer's lethal couriers with nanochains

September 25, 2012 8:02 am | News | Comments

Malignant cells that leave a primary tumor, travel the bloodstream and grow out of control in new locations cause the vast majority of cancer deaths. New nanotechnology developed at Case Western Reserve University detects these metastases in mouse models of breast cancer far earlier than current methods, a step toward earlier, life-saving diagnosis and treatment.

New breast cancer clues found in gene analysis

September 24, 2012 4:37 am | News | Comments

Scientists reported Sunday that they have completed a major analysis of the genetics of breast cancer, finding four major classes of the disease. The new finding, which is the latest example of research into the biological details of tumors, offers hints that one type of breast cancer might be vulnerable to drugs that already work against ovarian cancer.

Cancer research yields unexpected way to produce nylon

September 24, 2012 3:50 am | News | Comments

In their quest for a cancer cure, researchers at the Duke Cancer Institute made a serendipitous discovery: a molecule necessary for cheaper and greener way to produce nylon. The finding arose from an intriguing notion that some of the genetic and chemical changes in cancer tumors might be harnessed for beneficial uses.

Diseases of aging map to a few “hotspots” on the human genome

September 19, 2012 9:19 am | News | Comments

Researchers have long known that individual diseases are associated with genes in specific locations of the genome. Now, genetics researchers have shown definitively that a small number of places in the human genome are associated with a large number and variety of diseases. In particular, several diseases of aging are associated with a locus which is more famous for its role in preventing cancer.

Chemists develop nose-like sensor array to “smell” cancer diagnoses

September 13, 2012 12:36 pm | News | Comments

In a pre-clinical non-small-cell lung cancer metastasis model in mice, a research team at the University of Massachusetts, Amherst uses a sensor array system of gold nanoparticles and proteins to “smell” different cancer types in much the same way our noses identify and remember different odors.

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