Advertisement
Biotechnology
Subscribe to Biotechnology
View Sample

FREE Email Newsletter

DNA motor “walks” along nanotube, transports tiny particle

December 17, 2013 2:45 pm | by Emil Venere, Purdue Univ. | News | Comments

Researchers have created a new type of molecular motor made of DNA and demonstrated its potential by using it to transport a nanoparticle along the length of a carbon nanotube. The design was inspired by natural biological motors that have evolved to perform specific tasks critical to the function of cells.

Berkeley Lab creates first soluble 2-D supramolecular organic frameworks

December 17, 2013 12:53 am | News | Comments

Metal-organic frameworks (MOFs) are commanding considerable research attention because of their appetite for greenhouse gases. But now supramolecular organic frameworks (SOFs), held together by non-covalent bonds, have joined the field. Researchers have unveiled the first 2-D SOFs that self-assemble in solution, an important breakthrough that holds implications for sensing, separation technologies, and biomimetics.

Golden trap: Highly sensitive system detects individual nanoparticles

December 17, 2013 12:45 am | by Uta Bilow, Helmholtz-Zentrum Dresden-Rossendorf | News | Comments

Medical diagnostics seeks to learn early on whether a serious disease is developing or what its course will be. In many cases, treacherous molecules are present only in trace amounts, however. Researchers in Germany have come up with a new method of detection which has allowed them to notice the presence of only 17 dye molecules. The highly sensitive method might one day be used to scan a tiny drop of blood for potential diseases.

Advertisement

The synaptic mechanisms behind brain waves

December 17, 2013 12:20 am | News | Comments

How information is processed and encoded in the brain is a central question in neuroscience. But the brain's underlying synaptic mechanisms have so far remained unclear. In a recent study, researchers have discovered the synaptic mechanisms underlying oscillations in the hippocampus. Furthermore, the researchers suggest a role for these oscillations in the coding of information by the principal neurons in that area of the brain.

Hybrid carrier five times more effective in delivering genetic material into cells

December 16, 2013 2:48 pm | News | Comments

Researchers in New York City have developed a carrier in their lab that is five times more efficient in delivering DNA into cells than today’s commercial delivery methods: reagent vectors. This novel complex is a peptide-polymer hybrid, assembled from two separate, less effective vectors that are used to carry DNA into cells.

3-D printed implants may soon fix complex injuries

December 13, 2013 2:54 pm | by Katie Feldman, National Science Foundation | News | Comments

Researchers are adapting technology for 3-D printing metals, ceramics, and other materials to create custom medical implants designed to fix complicated injuries. Using a technology called Laser Engineered Net Shaping (LENS), these new implants integrate into the body more effectively, encouraging bone regrowth that ultimately results in a stronger, longer lasting implant.

Engineers make strides toward artificial cartilage

December 13, 2013 1:50 pm | News | Comments

A Duke Univ. research team has developed a better recipe for synthetic replacement cartilage in joints. Combining two innovative technologies, the team found a way to create artificial replacement tissue that mimics both the strength and suppleness of native cartilage. Articular cartilage is the tissue on the ends of bones where they meet at joints in the body.

Temperature-sensitive gelling scaffolds to regenerate craniofacial bone

December 11, 2013 2:59 pm | News | Comments

Rice Univ. bioengineers have developed a hydrogel scaffold for craniofacial bone tissue regeneration that starts as a liquid, solidifies into a gel in the body and liquefies again for removal. The material developed in a Rice laboratory is a soluble liquid at room temperature that can be injected to the point of need. At body temperature, it turns into a gel to help direct the formation of new bone to replace that damaged by injury.

Advertisement

Tech for Faster Diagnosis, Cures

December 10, 2013 2:52 pm | by Lindsay Hock | Articles | Comments

In January 2013, an assoc. prof of biomedical engineering at Columbia Univ., Samuel K. Sia, developed a lab-on-a-chip technology that not only checks a patient’s HIV status with a finger prick, it also synchronizes the results automatically and instantaneously with central health care records. The technology, developed in collaboration with OPKO Diagnostics and called mChip, performs all ELISA functions, and produces results within 15 min.

New tool assesses the impact of toxic agents in cells

December 10, 2013 9:21 am | News | Comments

By using optical techniques, researchers in Switzerland are now able to measure the concentration of the oxidizing substances produced by a damaged cell. This new biosensing technique for toxic agents also offers a new way to know more about the mechanisms of oxidative stress.

Innovative contact lens delivers glaucoma medication continuously

December 9, 2013 10:10 am | News | Comments

For nearly 50 years, contact lenses have been proposed as a means of ocular drug delivery that may someday replace eye drops, but achieving controlled drug release has been a significant challenge. Researchers in Massachusetts have made an advance in this direction with the development of a drug-eluting contact lens designed for prolonged delivery glaucoma medication.

Recycled plastic effective in killing drug-resistant fungi

December 9, 2013 9:46 am | News | Comments

Researchers in Singapore and at IBM Research in California have discovered a new, potentially life-saving application for polyethylene terephthalate (PET), which is widely used to make plastic bottles. They have successfully converted PET into a non-toxic biocompatible material with superior fungal killing properties. This could help prevent and treat various fungus-induced diseases such as keratitis.

“Smuggling” drugs at the cellular level

December 9, 2013 9:28 am | by Britt Faulstick, Drexel Univ. | News | Comments

Medicated adhesive patches have become a preferred method of delivery for everything from nicotine to hormones to motion sickness medication. Drexel Univ. researchers are trying to expand the possibilities of this system, which is called transdermal delivery, with the help of a cleverly designed delivery vehicle and an ultrasonic "push," or pressure from sound waves.

Advertisement

Ultrasound microscopy: Aid for surgeons makes the invisible, visible

December 9, 2013 9:17 am | News | Comments

An ultrasonic microscope emits a high frequency sound at an object, and the reflected sound captured by its lens is converted into a 2-D image of the object under scrutiny. Prof. Naohiro Hozumi in Japan is developing the technology to monitor living tissue and cell specimens for medical purposes.

Industry Breakout - Life Sciences

December 9, 2013 6:10 am | by R&D Magazine/Battelle | Articles | Comments

As represented in this Forecast, the life science industry includes biopharmaceuticals, medical instruments and devices, animal/agricultural bioscience and commercial research and testing. However, the industry’s R&D spending is driven primarily by the mass and research intensity of the biopharmaceutical sector, which accounts for nearly 85% of all expenditures.

Gene sequencing that everyone can afford

December 6, 2013 8:15 am | News | Comments

Researchers in China, working on the optimization of a third-generation sequencing technique based on nanopores, have found that long-chain DNA with low salt concentration is more conducive to the nanopore sequencing process. This finding may improve the efficiency of sequencing, and further low the cost of gene sequencing.

Collaboration yields new genetic variant data set for 1000 Genomes Project

December 5, 2013 9:33 am | News | Comments

DNAnexus has announced a collaboration with Stanford Univ. that has resulted in a new 1000 Genomes Project data set of genetic variation. Launched in January 2008, the 1000 Genomes Project was the first international effort to sequence a large number of individual genomes with the goal of developing a comprehensive and freely accessible resource on human genetic variation.

Osteoarthritis medicine delivered on-demand

December 5, 2013 9:23 am | News | Comments

Scientists are reporting development of a squishy gel that, when compressed at a key location such as a painful knee joint, releases anti-inflammatory medicine. The new material could someday deliver medications when and where osteoarthritis patients need it most.

Ultrathin “diagnostic skin” allows continuous patient monitoring

December 5, 2013 9:10 am | News | Comments

An international multidisciplinary team including researchers at the Univ. of Illinois at Urbana/Champaign and the National Institute of Biomedical Imaging and Bioengineering has developed  a sophisticated ”electronic skin” that adheres non-invasively to human skin, conforms well to contours, and provides a detailed temperature map of any surface of the body.

New tool profiles critical regulatory structures of RNA molecules

December 4, 2013 10:34 am | News | Comments

Scientists at Penn State Univ. have developed a method that enables a more accurate prediction of how ribonucleic acid molecules (RNAs) fold within living cells, shedding new light on how plants, as well as other living organisms, respond to environmental conditions. The advance was made possible by the ability to analyze more than 10,000 RNA molecules in a single cell.

Bruker receives FDA clearance to market MALDI Biotyper CA System

November 27, 2013 11:52 am | News | Comments

Bruker Corp. has announced that it has been granted U.S. FDA clearance under Section 510(k) to market its MALDI Biotyper CA System in the United States for the identification of Gram negative bacterial colonies cultured from human specimens. The clearance marks progress in Bruker’s efforts to develop MALDI-TOF mass spectrometry into the most advanced platform for clinical microbiology identification.

Engineer, cardiologist team up to make implanted devices “sticky”

November 27, 2013 9:24 am | by Eric Swedlund, Univ. of Arizona | News | Comments

Univ. of Arizona agricultural and biosystems engineering associate professor Jeong-Yeol Yoon and cardiology professor Dr. Marvin Slepian are testing nanotextured surfaces to improve how cardiovascular implant devices are attached in the body. The goal is to create a selectively sticky surface, favoring endothelial cell attachment, without favoring platelet attachment.

Scientists invent implantable slimming aid

November 27, 2013 6:22 am | by Peter Rüegg, ETH Zurich | News | Comments

A new innovation may help us deal with post-Thanksgiving guilt: Biotechnologists have constructed a genetic regulatory circuit from human components that monitors blood-fat levels. In response to excessive levels, it produces a messenger substance that signals satiety to the body. Tests on obese mice reveal that this helps them to lose weight.

FDA tells 23andMe to halt sales of genetic test

November 26, 2013 11:57 am | by Matthew Perrone, AP Health Writer | News | Comments

The Food and Drug Administration has ordered Google-backed genetic test maker 23andMe to halt sales of its personalized DNA test kits. In a warning letter posted online Monday, FDA regulators say that the Silicon Valley company has not shown that its tests are safe or effective despite "more than 14 face-to-face and teleconference meetings" and "hundreds of email exchanges."

Scientists find powerful tool for genetic engineering

November 22, 2013 10:54 am | News | Comments

Viruses can not only cause illnesses in humans, they also infect bacteria. Bacteria protect themselves with a kind of immune system that detects and “chops up” foreign DNA. Scientists have now shown that the dual-RNA guided enzyme Cas9 which is involved in the process has developed independently in various strains of bacteria. This enhances the potential of exploiting the bacterial immune system for genome engineering.

X
You may login with either your assigned username or your e-mail address.
The password field is case sensitive.
Loading