Scientists at Princeton University used off-the-shelf printing tools to create a functional ear that can "hear" radio frequencies far beyond the range of normal human capability. Standard tissue engineering involves seeding types of cells onto a scaffold of a polymer material called a hydrogel. But this method is not useful for complex 3D shapes, which is why researchers turned to 3D printing methods.
Researchers at the Synthetic Biology Project at the Woodrow Wilson International Center for Scholars have recently reported that the number of private and public entities conducting research in synthetic biology worldwide grew significantly between 2009 and 2013. Their findings, which include more than 500 organizations, are tracked on an interactive online map.
In 2012, more than 3 million people had stents inserted in their coronary arteries. But the longer a stent is in the body, the greater the risk of late-stage side effects. Studies have investigated iron- and magnesium-based bioabsorbable stents, but iron rusts and magnesium dissolves too fast. Recent research shows that a certain type of zinc alloy might be the answer.
Coating medical supplies with an antimicrobial material is one approach that bioengineers are using to combat the increasing spread of multidrug-resistant bacteria. A research team in Singapore has now developed a highly effective antimicrobial coating based on cationic polymers. The coating can be applied to medical equipment, such as catheters.
For the first time, human embryonic stem cells have been transformed into nerve cells that helped mice regain the ability to learn and remember. The study at the University of Wisconsin began with deliberate damage to a part of the brain that is involved in learning and memory.
How do nerve cells—which can each be up to three feet long in humans—keep from rupturing or falling apart? Recent research reports that axons, the long, cable-like projections on neurons, are made stronger by a unique modification of the common molecular building block of the cell skeleton. The finding may help guide the search for treatments for neurodegenerative diseases.
Not many people can run and read at the same time, because the relative location of the eyes to the text is constantly changing. This forces the eyes to constantly adjust. At Purdue University, an industrial engineering professor has introduced a new innovation called ReadingMate, which adjusts text on a monitor to counteract the bobbing motion of a runner's head so that the text appears still.
Stanford University School of Medicine scientists have succeeded in transforming skin cells directly into oligodendrocyte precursor cells, the cells that wrap nerve cells in the insulating myelin sheaths that help nerve signals propagate. The research was done in mice and rats, but if the approach also works with human cells, it could eventually lead to cell therapies for a variety of diseases of the nervous system.
A new class of tiny, injectable light-emitting diodes (LEDs) is illuminating the deep mysteries of the brain. Researchers at the University of Illinois at Urbana-Champaign and Washington University in St. Louis developed ultrathin, flexible optoelectronic devices—including LEDs the size of individual neurons—that are lighting the way for neuroscientists in the field of optogenetics and beyond.
A letter that scientist Francis Crick wrote to his son about his Nobel Prize-winning DNA discovery was sold to anonymous buyer at a New York City auction on Wednesday for a record-breaking $5.3 million. The price, which far exceeded the $1 million pre-sale estimate, was a record for a letter sold at auction, eclipsing an Abraham Lincoln letter that sold in April 2008 for $3.4 million including commission.
An advance in micromotor technology akin to the invention of cars that fuel themselves from the pavement or air, rather than gasoline or batteries, is opening the door to broad new medical and industrial uses for these tiny devices, scientists said here today. Their update on development of the motors—so small that thousands would fit inside this "o"—was part of the American Chemical Society national meeting.
Scientists at the Uniersity of North Carolina at Chapel Hill School of Medicine have "rationally rewired" some of the cell's smallest components to create proteins that can be switched on or off by command. These "protein switches" can be used to interrogate the inner workings of each cell, helping scientists uncover the molecular mechanisms of human health and disease.
Sandia National Laboratories is developing a suite of complementary technologies to help the emerging algae industry detect and quickly recover from algal pond crashes, an obstacle to large-scale algae cultivation for future biofuels. The research draws upon Sandia's longstanding expertise in microfluidics technology, its strong bioscience research program and significant internal investments.
The Office of Naval Research (ONR) this week launched a collaborative initiative with university researchers focused on synthetic, or engineered, cells—part of a larger effort to use the smallest units of life to help Sailors and Marines execute their missions. ONR currently has multiple ongoing projects in the field of synthetic biology.
Another innovative feature has been added to the world’s first practical “artificial leaf,” making the device even more suitable for providing people in developing countries and remote areas with electricity, scientists reported at the American Chemical Society’s National Meeting & Exposition this week. It gives the leaf the ability to self-heal damage that occurs during production of energy.
Researchers at Lund University in Sweden have discovered a new protein that controls the presence of the Vel blood group antigen on our red blood cells. The discovery makes it possible to use simple DNA testing to find blood donors for patients who lack the Vel antigen and need a blood transfusion. This is significant because there is a global shortage of Vel-negative blood
Scientists this week described technology that accelerates microalgae’s ability to produce many different types of renewable oils for fuels, chemicals, foods and personal-care products within days using standard industrial fermentation. On highlight was Solazyme, which has achieved more than 80% oil within each individual cell of microalgae at the commercial scale.
Researchers from the RIKEN Brain Science Institute report that they successfully used a virus vector to restore the expression of a brain protein and improve cognitive functions, in a mouse model of Alzheimer's disease. Because it is impossible to deliver genes directly to the brain without surgery, the researchers injected the virus in the left ventricle of the heart, as this provides a direct route to the brain.
The NeuroBlate Thermal Therapy System is a new device that uses a minimally invasive, magnetic resonance imaging (MRI)-guided laser system to coagulate, or heat and kill, brain tumors. The MRI basically "cooks" brain tumors in a controlled fashion to destroy them. The first-in-human study of the system finds that it appears to provide a new, safe and minimally invasive procedure for treating recurrent glioblastoma, a malignant type of brain tumor.
People who are hard of hearing can quickly drift into social isolation. Worse, they can also get into dangerous situations, for example when driving or crossing the road. For many of them, their hearing is so damaged that a standard hearing aid is no longer enough. A new device developed by researchers in Europe is intended to improve patients’ hearing and can be implanted during outpatient surgery.
Although bladder cancer is the sixth most common form of cancer in the U.S. and the most expensive to treat, the basic method that doctors use to treat it hasn’t changed much in more than 70 years. A research team may soon be changing that dramatically after having developed a prototype telerobotic platform designed to be inserted through natural orifices—in this case the urethra—that can provide surgeons with a much better view, making it easier to remove tumors.
A sensing system developed at the University of Cambridge is being commercialized in the U.K. for use in rapid, low-cost DNA sequencing, which would make the prediction and diagnosis of disease more efficient, and individualized treatment more affordable.
Researchers at Sandia National Laboratories are developing a medical instrument that will be able to quickly detect a suite of biothreat agents, including anthrax, ricin, botulinum, shiga, and SEB toxin. The device, once developed, approved by the U.S. Food and Drug Administration, and commercialized, would most likely be used in emergency rooms in the event of a bioterrorism incident.
Porous polymer scaffolds fabricated to support the growth of biological tissue for implantation may hold the potential to greatly accelerate the development of cancer therapeutics. Researchers at Rice University, the University of Texas MD Anderson Cancer Center, and Mount Sinai Medical Center reported that 3D scaffolds used to culture Ewing's sarcoma cells were effective at mimicking the environment in which such tumors develop.
Current methods of detecting microRNA (miRNA) can be time consuming and costly: The custom equipment used in such tests costs more than $100,000, and the limited throughput of these systems further hinders progress. Two Massachusetts Institute of Technology alumni are helping to rectify these issues through their fast-growing, Cambridge-headquartered startup, Firefly BioWorks Inc., which provides technology that allows for rapid miRNA detection in a large number of samples using standard laboratory equipment.