Scientists have developed a new technique allowing the bioprinting at ambient temperatures of a strong paste similar to play dough capable of incorporating protein-releasing microspheres. The scientists demonstrated the bioprinted material, in the form of a microparticle paste capable of being injected via a syringe, could sustain stresses and strains similar to cancellous bone.
Rice Univ. has been awarded a $1 million grant by the W.M. Keck Foundation to develop gas-...
The vast majority of the thousands of chemicals in our homes and workplaces have not been tested...
Traumatic injuries, whether from serious car accidents, street violence or military combat, can lead to significant blood loss and death. But using a material derived from crustacean shells, scientists have now developed a foam that can be sprayed onto an open wound to stop the bleeding. They report their successful tests on pigs in ACS Biomaterials Science & Engineering.
The global rise in antibiotic resistance is a growing threat to public health, damaging our ability to fight deadly infections such as tuberculosis. What’s more, efforts to develop new antibiotics are not keeping pace with this growth in microbial resistance, resulting in a pressing need for new approaches to tackle bacterial infection.
Researchers from the Univ. of Illinois at Urbana-Champaign have, for the first time, uncovered the complex interdependence and orchestration of metabolic reactions, gene regulation and environmental cues of clostridial metabolism, providing new insights for advanced biofuel development.
Cancerous tumors cast off tiny telltale genetic molecules known as microRNAs and Univ. of Michigan researchers have come up with an efficient way to detect them in blood. The researchers say their approach could open the door to a single, inexpensive blood test to simultaneously screen for multiple types of cancer, eventually perhaps more than 100 different kinds.
Silk inks containing enzymes, antibiotics, antibodies, nanoparticles and growth factors could turn inkjet printing into a new, more effective tool for therapeutics, regenerative medicine and biosensing, according to new research led by Tufts Univ. biomedical engineers and published in Advanced Materials.
Cornell Univ. engineers have created a functional, synthetic immune organ that produces antibodies and can be controlled in the lab, completely separate from a living organism. The engineered organ has implications for everything from rapid production of immune therapies to new frontiers in cancer or infectious disease research.
Tissues and organs in the body are sometimes damaged to such an extent that they require artificial support to heal. Now, A*STAR researchers have used star-shaped polymers to produce a 3-D network that is both compatible with human tissue and facilitates cells to adhere and proliferate under controlled biological conditions.
Injectable electronics hold promise for basic neuroscience, treatment of neuro-degenerative diseasesJune 9, 2015 9:45 am | News | Comments
It's a notion that might be pulled from the pages of science-fiction novel — electronic devices that can be injected directly into the brain, or other body parts, and treat everything from neuro-degenerative disorders to paralysis. It sounds unlikely, until you visit Charles Lieber's lab.
Researchers at the Univ. of Georgia have used a gene-editing tool known as CRISPR/Cas to modify the genome of a tree species for the first time. Their research, published online in New Phytologist, opens the door to more rapid and reliable gene editing of plants. By mutating specific genes in Populus, the researchers reduced the concentrations of two naturally occurring plant polymers.
Biochemists from Trinity College Dublin have devised a new technique that will make the difficult but critical job of blueprinting certain proteins considerably faster, easier and cheaper. The breakthrough will make a big splash in the field of drug discovery and development, where precise protein structure blueprints can help researchers understand how individual proteins work.
The future of medicine lies in ever greater precision, not only when it comes to diagnosis but also drug dosage. The blood work that medical staff rely on is generally a snapshot indicative of the moment the blood is drawn before it undergoes hours, or even days, of analysis. Several EPFL laboratories are working on devices allowing constant analysis over as long a period as possible.
Reporting on their study with lab-grown human cells, researchers at The Johns Hopkins Univ. and the Univ. of Maryland say that blocking a second blood vessel growth protein, along with one that is already well-known, could offer a new way to treat and prevent a blinding eye disease caused by diabetes.
Massachusetts Institute of Technology researchers have shown that they can use a microfluidic cell-squeezing device to introduce specific antigens inside the immune system’s B cells, providing a new approach to developing and implementing antigen-presenting cell vaccines.
The latest version of a microfluidic device for capturing rare circulating tumor cells is the first designed specifically to capture clusters of two or more cells, rather than single cells. The new device, called the Cluster-Chip, was developed by the same Massachusetts General Hospital (MGH) research team that created previous microchip-based devices.
Biomedical devices that can be implanted in the body for drug delivery, tissue engineering or sensing can help improve treatment for many diseases. However, such devices are often susceptible to attack by the immune system, which can render them useless. A team of Massachusetts Institute of Technology researchers has come up with a way to reduce that immune-system rejection.
Fans of homebrewed beer and backyard distilleries already know how to employ yeast to convert sugar into alcohol. But a research team led by UC Berkeley bioengineers has gone much further by completing key steps needed to turn sugar-fed yeast into a microbial factory for producing morphine and potentially other drugs, including antibiotics and anti-cancer therapeutics.
The printer looks like a toaster oven with the front and sides removed. Its metal frame is built up around a stainless steel circle lit by an ultraviolet light. Stainless steel hydraulics and thin black tubes line the back edge, which lead to an inner, topside box made of red plastic. All together, the gray metal frame is small enough to fit on top of an old-fashioned school desk, but nothing about this 3D printer is old school.
A team of neuroscientists and bioengineers a have created a miniature, fiber-optic microscope designed to peer deeply inside a living brain. The laser-scanning microscope, a prototype which will be further refined, uses fiber-optics and a tiny electrowetting lens. Compared to other small, focusing lenses, it’s fast and not sensitive to motion. This allows it to reliably focus on living tissue.
A new technique invented at Massachusetts Institute of Technology can measure the relative positions of tiny particles as they flow through a fluidic channel, potentially offering an easy way to monitor the assembly of nanoparticles, or to study how mass is distributed within a cell. With further advancements, this technology has the potential to resolve the shape of objects in flow as small as viruses, the researchers say.
Decorating the outside of cells like tiny antenna, a diverse community of sugar molecules acts like a telecommunications system, sending and receiving information, recognizing and responding to foreign molecules and neighboring cells. This sugar part of biomembranes is as crucial to health as DNA, but not much is known about it.
An international team of researchers has created tiny, complex scaffolds that mimic the intricate network of collagen fibers that form the human eardrum. It is hoped the scaffolds can be used to replace eardrums when they become severely damaged, reducing the need for patients to have their own tissue used in reconstruction surgery.
Imagine taking strands of DNA and using it to build tiny structures that can deliver drugs to targets within the body or take electronic miniaturization to a whole new level. While it may still sound like science fiction to most of us, researchers have been piecing together and experimenting with DNA structures for decades.
Washington State Univ. researchers have found a way to make jet fuel from a common black fungus found in decaying leaves, soil and rotting fruit. The researchers hope the process leads to economically viable production of aviation biofuels in the next five years. The researchers used Aspergillus carbonarius ITEM 5010 to create hydrocarbons, the chief component of petroleum, similar to those in aviation fuels.
If you opt to wear soft contact lenses, chances are you are using hydrogels on a daily basis. Made up of polymer chains that are able to absorb water, hydrogels used in contacts are flexible and allow oxygen to pass through the lenses, keeping eyes healthy. Hydrogels can be up to 99% water and as a result are similar in composition to human tissues.
Researchers from the Georgia Institute of Technology have developed a novel cellular sensing platform that promises to expand the use of semiconductor technology in the development of next-generation bioscience and biotech applications. The research proposes and demonstrates the world’s first multi-modality cellular sensor arranged in a standard low-cost CMOS process.
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