Knowing virtually everything about how the body’s cells make transitions from one state to another would be a major jump forward in understanding the basics of what drives biological processes. An interdisciplinary team of researchers report on taking at least a step toward better comprehension of the fundamentals of “cell fate determination”.
According to NASA, there are more than 21,000 pieces of “space junk roughly the size of a baseball in orbit, and about 500,000 pieces that are golf ball-sized. These pieces can be dangerous, which is why researchers at Texas Advanced Computing Center’s supercomputers are simulating orbital debris impacts on spacecraft and fragment impacts on body armor to help NASA design better shielding.
The National Institute of Standards and Technology this week announced that it plans to establish a new Advanced Materials Center of Excellence to facilitate collaborations between NIST and researchers from academia and industry on advanced materials development. Fund at about $25 million over five years, the center will emphasize innovations in measurement technology, modeling, simulation, and data and informatics tools
How do fish swim? It is a simple question, but there is no simple answer. Researchers at Northwestern Univ. have revealed some of the mechanical properties that allow fish to perform their complex movements. Their findings could provide insights in evolutionary biology and lead to an understanding of the neural control of movement and development of bio-inspired underwater vehicles.
After analyzing genomic sequencing data from the Human Genome Project and other sources, scientists in Maryland have found evidence that lateral gene transfer is possible from bacteria to the cells of the human body, known as human somatic cells. They also found that bacterial DNA was more likely to integrate in the genome in tumor samples than in normal, healthy somatic cells.
JMAG is a powerful finite element analysis (FEA) tool that allows engineers to develop, analyze, and fine-tune electric motors and generators, taking into account such diverse factors as thermal, structural, and vibration issues. This week, Maplesoft has launched a new product that allows users to combine JMAG with the advanced physical modeling approach of MapleSim. This allows engineers to produce high-fidelity system models.
Rice Univ. researchers have for the first time detailed the molecular mechanism that makes a particular combination of cement and polymer glue so tough. The theoretical research led to a fine picture of how hydrogen bonds control the properties of hybrid organic-inorganic materials. The finding has implications for understanding the interface bonding that is often a roadblock to improved composite properties.
An international team of scientists has developed crop models to better forecast food production to feed a growing population—projected to reach 9 billion by mid-century—in the face of climate change. The team recently unveiled an all-encompassing modeling system that integrates multiple crop simulations with improved climate change models.
On March 11, 2011, a magnitude 9.0 undersea earthquake occurred 43 miles off the shore of Japan. It generated an unexpectedly massive tsunami that washed over eastern Japan roughly 30 minutes later. Scientists at Stanford University have identified key acoustic characteristics of this quake that indicated it would cause a large tsunami.
Water is one of the most common and extensively studied substances on Earth. It is vital for all known forms of life but its unique behavior has yet to be explained in terms of the properties of individual molecules. A research team has now revealed a major breakthrough in the modeling of water that could shed light on its mysterious properties.
Lithium-ion batteries are lightweight, fully rechargeable and can pack a lot of energy into a small volume—making them attractive as power sources for hybrid and electric vehicles. However, there’s a significant downside: Overheating and collisions may cause the batteries to short-circuit and burst into flames. Engineers have worked to improve the safety of lithium-ion batteries and now there may be ways to make batteries more resilient.
Researchers report that they have determined the precise chemical structure of the HIV capsid, a protein shell that protects the virus’s genetic material and is a key to its virulence. The capsid has become an attractive target for the development of new antiretroviral drugs. The researchers used the University of Illinois’ supercomputer Blue Waters to determine the complete HIV capsid structure.
Environment is not the only factor in shaping cell regulatory patterns—and it might not even be the primary factor, according to a new Rice University study that looks at how cells’ protein networks relate to a bacteria’s genome. When environmental factors are eliminated from an evolutionary model, the researchers say, mutations and genetic drift can give rise to the patterns that appear.
All living cells have a regulatory system similar to what can be found in today's smartphones. Just like our phones process a large amount of information that we feed them, cells continuously process information about their outer and inner environment. Researchers have recently modeled how cells regulate this processing function.
Sulfur dioxide has been pegged as a significant cooling element in atmospheric climate models because of its ability to form sulfate aerosol particles that reflect sunlight. Recent findings from a team suggest that it is likely most models overestimate the cooling effect of these particles. The reason is a largely disregarded reaction pathway catalyzed by mineral dust within clouds.
The three different formations of South Pacific coral-reef islands, fringing, barrier, and atoll, have long fascinated geologists. The question of how reefs develop into these shapes over evolutionary time produced an enduring conflict between two hypotheses, one from Charles Darwin and the other from Reginald Daly. But in a recently published paper, researchers use modern measurements and computer modeling to resolve this old conundrum.
Bubble baths and soapy dishwater and the refreshing head on a beer: These are foams, beautiful yet ephemeral as the bubbles pop one by one. Now, a team of researchers has described mathematically the successive stages in the complex evolution and disappearance of foamy bubbles, a feat that could help in modeling industrial processes in which liquids mix or in the formation of solid foams such as those used to cushion bicycle helmets.
Ion channels are important drug targets. A team of researchers University of Vienna has investigated the opening and closing mechanisms of these channels, which represent large proteins with more than 400 amino acids. Their work for the first time calculates in atomic detail the full energy landscape of this protein.
Computer simulations conducted in Germany have shown that the reduction of natural dental wear might be the main cause for widely spread non-carius cervical lesions—the loss of enamel and dentine at the base of the crown—in our teeth. The discovery was made by examining the biomechanical behavior of teeth using finite element analysis methods typically applied to engineering problems.
Scientists have long observed that species seem to have become increasingly capable of evolving in response to changes in the environment. But computer science researchers now say that the popular explanation of competition to survive in nature may not actually be necessary for evolvability to increase.
In efforts to prioritize and efficiently manage the repair of boats and stations damaged by Superstorm Sandy, the U.S. Coast Guard has accredited a system called Coast Guard Search and Rescue Visual Analytics (cgSARVA) developed in collaboration with Purdue University.
To understand the development of sensory representations within our brain, we have to comprehend how electrical activation is linked to the sensory experience. For this reason, researchers in Italy have analyzed the behavior and the activation of neural networks in rats while carrying out tactile object recognition tests. The study represents the first time that the activity of multiple neurons has been monitored.
An engineer in Finland has designed a new evaluation model that allows developers to determine how fatigue sets in with various welded steel materials. By considering the differences between traditional welds and structural joining technologies and newer more advanced methods, he model allows for the development of lighter structures, and as a consequence, more energy-efficient ships.
A new global-scale modeling study that takes into account nitrogen—a key nutrient for plants—estimates that carbon emissions from human activities on land were 40% higher in the 1990s than in studies that did not account for nitrogen. Most existing models used to estimate global emissions changes based on land use do not have the ability to model nitrogen limitations on plant regrowth.
A research team from Aalto University has modeled the work processes and human decision making in scientific peer review with the help of statistical physics. Their study will improve understanding of how actions of reviewers and editors during the review work correlate with the decisions to publish or reject article manuscripts.