A new online database combining symptoms, family history and genetic sequencing information is speeding the search for diseases caused by a single rogue gene. As described in an article in the May issue of Human Mutation, the database, known as PhenoDB, enables any clinician to document cases of unusual genetic diseases for analysis by researchers at the Johns Hopkins University School of Medicine or the Baylor College of Medicine.
Columbia University has signed a licensing agreement with Varian Medical Systems for...
The University of Chicago has recently launched the first secure cloud-based...
Ion channels are important drug targets. A team of researchers University of Vienna...
Researchers at Columbia University and Stanford University have developed a computational method that enables scientists to visualize and interpret "high-dimensional" data produced by single-cell measurement technologies such as mass cytometry. A sophisticated algorithm converts difficult-to-interpret data into visual representations similar to two-dimensional "scatter plots".
Engineers combine layers of flexible materials into pressure sensors to create a wearable heart monitor thinner than a dollar bill. The skin-like device could one day provide doctors with a safer way to check the condition of a patient's heart.
In a provocative new study, scientists reported Wednesday that they were able to "see" pain on brain scans and, for the first time, measure its intensity and tell whether a drug was relieving it. Though the research is in its early stages, it opens the door to a host of possibilities. For example, scans might be used someday to tell when pain is hurting a baby, someone with dementia, or a paralyzed person unable to talk.
Although bladder cancer is the sixth most common form of cancer in the U.S. and the most expensive to treat, the basic method that doctors use to treat it hasn’t changed much in more than 70 years. A research team may soon be changing that dramatically after having developed a prototype telerobotic platform designed to be inserted through natural orifices—in this case the urethra—that can provide surgeons with a much better view, making it easier to remove tumors.
A compact, self-contained sensor recorded and transmitted brain activity data wirelessly for more than a year in early stage animal tests, according to a recent study funded by the National Institutes of Health. In addition to allowing for more natural studies of brain activity in moving subjects, this implantable device represents a potential major step toward cord-free control of advanced prosthetics that move with the power of thought
A team of neuroengineers based at Brown University has developed a fully implantable and rechargeable wireless brain sensor capable of relaying real-time broadband signals from up to 100 neurons in freely moving subjects. Several copies of the novel low-power device have been performing well in animal models for more than year, a first in the brain-computer interface field.
Researchers at Pompeu Fabra University (Spain) have created a high resolution atlas of the heart with 3D images taken from 138 people. The study demonstrates that an average image of an organ along with its variations can be obtained for the purposes of comparing individual cases and differentiating healthy forms from pathologies.
Our ancestors evolutionarily split from those of rhesus monkeys about 25 million years ago. Since then, brain areas have been added, have disappeared, or have changed in function. This raises the question: Has evolution given humans unique brain structures? Previous research has been inconclusive, but by combining different research methods, researchers in The Netherlands now say they have the first piece of evidence that could prove that humans have unique cortical brain networks.
Take a walk through a human brain? Fly over the surface of Mars? Computer scientists at the University of Illinois at Chicago are pushing science fiction closer to reality with a wraparound virtual world where a researcher wearing 3D glasses can do all that and more. In the system, known as CAVE2, a 8-foot-high screen encircles the viewer 320 degrees. A panorama of images springs from 72 stereoscopic liquid crystal display panels, conveying a dizzying sense of being able to touch what's not really there.
Researchers have recently demonstrated magnetic resonance imaging (MRI) on the molecular scale through the use of artificial atoms, diamond nanoparticles doped with nitrogen impurity. Conventional MRI responds to the magnetic fields of atomic nuclei, but this new method improves resolution nearly one million times, allowing scientists to probe very weak magnetic fields such as those generated in some biological molecules and even proteins.
The connection between poor sleep, memory loss and brain deterioration as we grow older has been elusive. But for the first time, scientists at the University of California, Berkeley, have found a link between these hallmark maladies of old age. Their discovery opens the door to boosting the quality of sleep in elderly people to improve memory.
A new software tool, developed at The Children's Hospital of Philadelphia, streamlines the detection of disease-causing genetic changes through more sensitive detection methods and by automatically correcting for variations that reduce the accuracy of results in conventional software. The software, called ParseCNV, is freely available to the scientific-academic community.
The development of functional magnetic resonance imaging (fMRI)—a tool used to gauge real-time brain activity by measuring changes in blood flow—has given researchers the opportunity to try to answer various questions about the brain and mind. But some are not convinced of its usefulness, and a new report published by Association for Psychological Science takes stock of what fMRI has actually accomplished.
Health care providers and hospitals are being offered up to $27 billion in federal incentives to use electronic health records (EHRs) in ways that demonstrably improve the quality of care. The incentives are based, in part, on the ability to electronically report clinical quality measures. A new study has found ways in which quality measurement from EHRs—which are primarily designed for documentation of clinical care for individual patients—can be improved
Physicians may soon have a better alternative to endoscopy for screening patients for Barrett's esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at Massachusetts General Hospital have developed an imaging system enclosed in a capsule about the size of a multivitamin pill that creates detailed, microscopic images of the esophageal wall.
Doctors may soon be using a system in the operating room that recognizes hand gestures as commands to tell a computer to browse and display medical images of the patient during a surgery. Purdue University researchers are creating a system that uses depth-sensing cameras and specialized algorithms to recognize hand gestures as commands to manipulate MRI images on a large display.
Because of the limited image spatial-resolution of even today's best-quality laptop and desktop computers, researchers and physicians often can’t see phenomena that are too large, too small, too complex, or too distant. CAVE2, a next-generation, large-scale virtual environment, combines the benefits of scalable-resolution display walls with virtual-reality system to create a revealing and seamless 2D and 3D environment that is becoming increasingly important in scientific discovery.
A research team has used stretchable electronics to create a multipurpose medical catheter that can both monitor heart functions and perform corrections on heart tissue during surgery. The device marks the first time stretchable electronics have been applied to a surgical process known as cardiac ablation, a milestone that could lead to simpler surgeries for arrhythmia and other heart conditions.
Electrical engineers at Oregon State University have developed new technology to monitor medical vital signs, with sophisticated sensors so small and cheap they could fit onto a bandage, be manufactured in high volumes, and cost less than a quarter. A patent is being processed for the monitoring system and it's now ready for clinical trials, researchers say.
A thin, flexible electrode developed at the University of Michigan is 10 times smaller than the nearest competition and could make long-term measurements of neural activity practical at last. This kind of technology could eventually be used to send signals to prosthetic limbs, overcoming inflammation larger electrodes cause that damages both the brain and the electrodes.
A new iPhone app developed at the University of Michigan lets migraine or facial pain patients easily track and record their pain, which in turn helps the treating clinician develop a pain management plan.
Johns Hopkins Medicine researchers have succeeded in teaching computers how to identify commonalities in DNA sequences known to regulate gene activity, and to then use those commonalities to predict other regulatory regions throughout the genome. The tool is expected to help scientists better understand disease risk and cell development.
An international team of scientists has discovered a new method for coloring the cell wall of bacterial cells to determine how they grow. Multicolored probes target cell wall synthesis, labeling them with nontoxic dyes. The technique provides a new, much-needed tool for the development of new antibiotics.