A collaboration has been announced between Agilent Technologies and the Univ. of Toronto’s Donnelly Centre for Cellular and Biomolecular Research to produce a comprehensive metabolomics multiple-reaction monitoring library and methodology, using Agilent’s Infinity 1290 UHPLC, 6460 triple quadrupole mass spectrometry system, and MassHunter Software. The goal is to accelerate quantification of hundreds of metabolically important compounds.
An ambitious health startup from Google is teaming...
Several prominent leaders in neuroscience research...
Popping the blisters on the bubble wrap might be...
Oxford Gene Technology has announced the launch of a new high-resolution, high-throughput pre-implantation genetic screening (PGS) microarray aimed at improving embryo screening for in vitro fertilization. The CytoSure Embryo Screen Array offers eight arrays of 60,000 spots for high-resolution genome-wide aneuploidy and copy number detection in pre-implantation embryos.
Scientists in Switzerland have developed a fast and accurate method for determining exactly which proteins cause allergies to milk. The novel approach, which is based on a specialized form of laser desorption-ionization mass spectrometry, is highly personalized and can extend to other foods as well.
In a basement laboratory at Fort Sam Houston military base in Texas, a research team has spent the last two years simulating improvised explosive device blasts on postmortem pig eyes using a high-powered shock tube. Their most striking discovery is that these blasts can damage the optic nerve, and these injuries can occur even at low pressures, causing visual defects that until now have been associated traumatic brain injuries.
Biochrom Ltd, a manufacturer of scientific instruments, and Gilson, a leader in fluidics, purification and sample management, announced an agreement to co-market and distribute in Europe products for automation of ELISAs and other absorbance assays. The partnership combines the strength of the EZ Read range of microplate readers from Biochrom, with Gilson’s innovative line of liquid handling systems.
A new “lab-on-a-chip” platform developed at the Institute of Photonic Sciences in Spain is capable of detecting detect very low concentrations of protein cancer markers, enabling diagnoses of the disease in its earliest stages. The device, just a few square centimeters in size, uses recent advances in plasmonics, nano-fabrication, microfluids and surface chemistry.
Counterfeit or adulterated olive oil has been a persistent presence on the market, in part because the oil is difficult to track. An invisible label, developed by researchers in Switzerland, could perform this task. The tag consists of tiny magnetic DNA particles encapsulated in a silica casing and mixed with the oil. Just a few grams of the new substance are enough to tag the entire olive oil production of Italy.
On the less glamorous side of space exploration, there’s the more practical problem of waste: in particular, what to do with astronaut pee. But rather than ejecting it into space, scientists are developing a new technique that can turn this waste burden into a boon by converting it into fuel and much-needed drinking water.
The Japanese scientist accused of falsifying data in a widely heralded stem-cell research paper said Wednesday the results are valid despite mistakes in their presentation. Haruko Obokata, 30, struggled to maintain her composure during a televised news conference packed with hundreds of reporters, but insisted she did not tamper with the data to fabricate results.
Researchers have discovered that the so-called HOPE method allows tissue samples to be treated such that they do not only meet the requirements of clinical histology, but can still be characterized later on by modern methods of proteomics, a technique that analyzes all proteins at once. This differs from the traditional formalin-based approach that cross-links protein molecules.
New research is focusing on enhancing poplar trees so they can break down easier and thus improving their viability as a biofuel. The long-term efforts and teamwork involved to find this solution can be described as a rare, top-down approach to engineering plants for digestibility.
Scientists have created a detailed, three-dimensional wiring diagram of the mouse brain. That should help researchers seek clues about how the human brain works in health and disease.
Scientists have published the first study explaining in detail how viruses reprogram the metabolism of the cells they invade to promote continued viral growth within an organism.
As the Earth’s human population marches toward 9 billion, the need for hardy new varieties of grain crops has never been greater. It won’t be enough to yield record harvests under perfect conditions; new grains must also be able to handle stress from climate changes. Researchers in Michigan have recently identified a set of genes that could be key to the development of the next generation of super rice.
Wounds may heal more quickly if exposed to low-intensity vibration, report researchers at the Univ. of Illinois at Chicago. The finding, in mice, may hold promise for the 18 million Americans who have type 2 diabetes, and especially the quarter of them who will eventually suffer from foot ulcers. Their wounds tend to heal slowly and can become chronic or worsen rapidly.
A new organ has been developed at George Washington Univ. to help return blood flow from veins lacking functional valves. A rhythmically contracting cuff made of cardiac muscle cells surrounds the vein acting as a 'mini heart' to aid blood flow through venous segments. The cuff can be made of a patient’s own adult stem cells, eliminating the chance of implant rejection.
A new microfluidic method for evaluating drugs commonly used for preventing heart attacks has found that while aspirin can prevent dangerous blood clots in some at-risk patients, it may not be effective in all patients with narrowed arteries. The study, a first in the examination of heart attack prevention drugs, used a device that simulated blood flowing through narrowed coronary arteries to assess effects of anti-clotting drugs.
AMSBIO has announced the launch of ClioCell, an ex vivo device for removal of dying and dead cells, improving viability and quality of cell populations and their subsequent productivity. The system comprises super-paramagnetic nanoparticles which have been coupled with proprietary elements that bind to dead and dying cells and cell debris.
When cancers become advanced, tumor cells from the primary tumor can enter the bloodstream and cause metastasis at another organ with deadly effect. While researching the biological implications of CTC spread, Creatv MicroTech researchers found a group of previously unreported cells associated with primary cancer spread. These macrophage-like cells could serve as biomarkers.
Scientists in the U.K. have proposed a new computer-based method of screening drugs that could be used to slow the aging process in humans. The proposed method uses gene expression data from “young” and “old” tissues to construct the cloud of molecular signalling pathways involved in ageing and longevity. It then evaluates the effects of a large number of drugs and drug combinations to emulate a youthful state for cells and tissues.
Over the past 20 years, the number of laboratory tests available to primary care physicians has doubled, to more than 3,500 tests, and physicians are challenged by the quantity of tests available. A recent survey conducted by the U.S. Centers for Disease Control and Prevention suggests they often face uncertainty in ordering and interpreting clinical laboratory tests, and would welcome better electronic clinical decision support tools.
Beckman Coulter Life Sciences has announced an agreement with Wyatt Technology Corp. to enable collaboration on products, applications and technical development. The partnership brings together Wyatt’s expertise in protein characterization, light scattering and biophysics with Beckman Coulter’s expertise in particle counting, particle characterization and cell viability measurement.
For people whose hands shake uncontrollably due to a medical condition, just eating can be a frustrating and embarrassing ordeal, enough to keep them from sharing a meal with others. But a small new study conducted at the Univ. of Michigan Health System suggests that a new handheld electronic device can help such patients overcome the hand shakes caused by essential tremor, the most common movement disorder.
At a recent two-day meeting, the Food and Drug Administration heard from supporters and opponents of a provocative new technique meant to prevent children from inheriting debilitating diseases. The method creates babies from the DNA of three people, and the agency is considering whether to greenlight testing in women who have defective genes.
For more than two years, researchers have been investigating melanopsin, a retina pigment capable of sensing light changes in the environment, informing the nervous system and synchronizing it with the day/night rhythm. They have found that this pigment is potentially more sensitive to light than its more famous counterpart rhodopsin, the pigment that allows night vision.
In research that could ultimately lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute have developed a potentially general approach to design drugs from genome sequence. As a proof of principle, they identified a highly potent compound that causes cancer cells to attack themselves and die.
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