Valium, one of the best known antianxiety drugs, produces its calming effects by binding with a particular protein in the brain. But the drug has an almost equally strong affinity for a completely different protein. Understanding this secondary interaction might offer clues about Valium's side effects and point the way to more effective drugs.
The idea of computing systems based on controlling atomic spins just got a boost from new...
Reducing the amount of sunlight that bounces off the surface of solar cells helps maximize the...
The discovery of "topologically protected" electrical conductivity on the surface of some...
One challenge in improving the efficiency of solar cells is some of the absorbed light energy is lost as heat. So scientists have been looking to design materials that can convert more of that energy into useful electricity. Now a team from Brookhaven National Laboratory and Columbia Univ. has paired up polymers that recover some of that lost energy by producing two electrical charge carriers per unit of light instead of the usual one.
Plans for the construction of the world's largest digital camera at the SLAC National Accelerator Laboratory have reached a major milestone. The 3,200-megapixel centerpiece of the Large Synoptic Survey Telescope, which will provide unprecedented details of the universe and help address some of its biggest mysteries, has received key "Critical Decision 2" approval from the DOE.
In a promising lithium-based battery, the formation of a highly conductive silver matrix transforms a material otherwise plagued by low conductivity. To optimize these multi-metallic batteries, scientists needed a way to see where, when and how these silver, nanoscale "bridges" emerge. Now, researchers have used x-rays to map this changing atomic architecture and revealed its link to the battery's rate of discharge.
A team of scientists has discovered an unusual form of electronic order in a new family of unconventional superconductors. The findingestablishes an unexpected connection between this new group of titanium-oxypnictide superconductors and the more familiar cuprates and iron-pnictides, providing scientists with a whole new family of materials from which they can gain deeper insights into the mysteries of high-temperature superconductivity.
A new discovery about the atomic structure of uranium dioxide will help scientists select the best computational model to simulate severe nuclear reactor accidents. Using the Advanced Photon Source, a team of researchers found that the atomic structure of uranium dioxide (UO2) changes significantly when it melts.
A collaboration blending research in U.S. Dept. of Energy's offices of High-Energy Physics (HEP) with Basic Energy Sciences (BES) will yield a one-of-a-kind x-ray detector. The device boasts Brookhaven National Laboratory sensors mounted on Fermilab integrated circuits linked to Argonne National Laboratory data acquisition systems. It will be used at Brookhaven's National Synchrotron Light Source II and Argonne's Advanced Photon Source.
Results from experiments at the Relativistic Heavy Ion Collider, a particle collider located at the Brookhaven National Laboratory, reveal new insights about how quarks and gluons, the subatomic building blocks of protons, contribute to the proton’s intrinsic angular momentum, a property more commonly known as “spin.”
The proteins that drive DNA replication are some of the most complex machines on Earth and the process involves hundreds of atomic-scale moving parts that rapidly interact and transform. Now, scientists have pinpointed crucial steps in the beginning of the replication process, including surprising structural details about the enzyme that "unzips" and splits the DNA double helix so the two halves can serve as templates for DNA duplication.
Mazhar Ali, a fifth-year graduate student in the laboratory of Bob Cava, the Russell Wellman Moore Professor of Chemistry at Princeton Univ., has spent his academic career discovering new superconductors, materials coveted for their ability to let electrons flow without resistance. While testing his latest candidate, the semimetal tungsten ditelluride (WTe2), he noticed a peculiar result.
Hepatitis C, an infectious disease of the liver caused by the hepatitis C virus (HCV), affects 160 million people worldwide. There’s no vaccine for HCV and the few treatments that are available do not work on all variants of the virus. Before scientists can develop potential vaccines and additional therapies they must first thoroughly understand the molecular-level activity that takes place when the virus infects a host cell.
Increasing the oil content of plant biomass could help fulfill the nation's increasing demand for renewable energy feedstocks. But many of the details of how plant leaves make and break down oils have remained a mystery. Now a series of detailed genetic studies conducted at Brookhaven National Laboratory reveals previously unknown biochemical details about those metabolic pathways.
Heat drives classical phase transitions, but much stranger things can happen when the temperature drops. If phase transitions occur at the coldest temperatures imaginable, where quantum mechanics reigns, subtle fluctuations can dramatically transform a material. Scientists have explored this frigid landscape of absolute zero to isolate and probe these quantum phase transitions with unprecedented precision.
Using a calculation originally proposed seven years ago to be performed on a petaflop computer, Lawrence Livermore National Laboratory researchers computed conditions that simulate the birth of the universe. When the universe was less than one microsecond old and more than one trillion degrees, it transformed from a plasma of quarks and gluons into bound states of quarks.
Cadmium zinc telluride (CZT) gamma-ray detectors are important new components in spectroscopic imaging systems because they are the first detectors capable of distinguishing natural gamma-ray background and radioactive isotopes without the need for bulky cooling equipment. The technological difficulties of producing perfect crystals, however, have hindered widespread usage. Brookhaven National Laboratory has successfully addressed these challenges with the introduction of the GammaScout.
New supercomputing calculations provide the first evidence that particles predicted by the theory of quark-gluon interactions but never before observed are being produced in heavy-ion collisions at the Relativistic Heavy Ion Collider, a facility that is dedicated to studying nuclear physics. These heavy strange baryons, containing at least one strange quark, still cannot be observed directly.
Electronic devices with unprecedented efficiency and data storage may someday run on ferroelectrics—remarkable materials that use built-in electric polarizations to read and write digital information, outperforming the magnets inside most popular data-driven technology. But ferroelectrics must first overcome a few key stumbling blocks, including a curious habit of "forgetting" stored data.
Using a new method to track the electrochemical reactions in a common electric vehicle battery material under operating conditions, scientists at Brookhaven National Laboratory have revealed new insight into why fast charging inhibits this material's performance. The study also provides the first direct experimental evidence to support a particular model of the electrochemical reaction.
Lithium (Li)-ion batteries power almost all of the portable electronic devices that we use every day, including smartphones, cameras, toys and even electric cars. Researchers across the globe are working to find materials that will lead to safe, cheap, long-lasting and powerful Li-ion batteries.
Scientists running the ATLAS experiment at the Large Hadron Collider report the first evidence of a process that can be used to test the mechanism by which the recently discovered Higgs particle imparts mass to other fundamental particles. More rare than the production of the Higgs itself, this process also provides a new stringent test of the Standard Model of particle physics.
Researchers at The Johns Hopkins Univ. report they have deciphered the inner workings of a protein called YiiP that prevents the lethal buildup of zinc inside bacteria. They say understanding YiiP's movements will help in the design of drugs aimed at modifying the behavior of ZnT proteins, eight human proteins that are similar to YiiP, which play important roles in hormone secretion and in signaling between neurons.
Scientists seeking ways to engineer the assembly of tiny particles measuring just billionths of a meter have achieved a new first: the formation of a single layer of nanoparticles on a liquid surface where the properties of the layer can be easily switched. Understanding the assembly of such nanostructured thin films could lead to the design of new kinds of membranes with a variable mechanical response for a wide range of applications.
Sometimes a cell has to die—when it's done with its job or inflicted with injury that could otherwise harm an organism. Conversely, cells that refuse to die when expected can lead to cancer. So scientists interested in fighting cancer have been keenly interested in learning the details of "programmed cell death." They want to understand what happens when this process goes awry and identify new targets for anticancer drugs.
Wouldn’t it be nice to use solar- or wind-generated electricity to turn excess carbon dioxide into fuels and other useful chemicals? The process would store up the intermittent solar or wind energy in a form that could be used when and where it was needed, including in transportation applications, all while getting rid of some greenhouse gas.
Batteries don’t age gracefully. The lithium ions that power portable electronics cause lingering structural damage with each cycle of charge and discharge, making devices from smartphones to tablets tick toward zero faster and faster over time. To stop or slow this steady degradation, scientists must track and tweak the imperfect chemistry of lithium-ion batteries with nanoscale precision.
In recent work at Brookhaven National Laboratory, semiconductor quantum dots (QDs) have been combined with graphene to develop nanoscale photonic devices that can dramatically improve our ability to detect light. The research has demonstrated that the thickness of the organic molecule layer that typically surrounds the QDs is crucial in attaining sufficiently high efficiency of light/energy transfer into the graphene.
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