Commercially available as instrumentation designed for macro-size sampling, Raman spectroscopy drew interest for providing information similar but complementary to infrared (FTIR) spectroscopy for chemical identification. In addition to chemical fingerprinting, the technique could provide molecular backbone information, materials morphology, sensitivity to symmetric bonds and the ability to analyze inorganic samples and components.
A rare, recently discovered microbe that survives on very little to eat has been found in two...
The increasingly powerful microscopes used in biomedical imaging provide biologists with 3-D images of hundreds of cells, and cells in these images are often layered on each other. Under these conditions, it is impossible for traditional computational methods to determine the cells' properties. Researchers have developed a virtual tool that can analyze dozens of images in just an hour. This works out to hundreds of cells.
Researchers using transmission electron microscopy have examined the smallest building block of coral that can be identified: sphemlites. These studies have revealed three distinct regions whose formation could be directly correlated to the time of day. These findings could help scientists and environmentalists working to protect and conserve coral from the threats of acidification and rising water temperatures.
A team of scientists in Europe have developed a new method of rapidly identifying different molecular species under a microscope. Their technique of coherent Raman spectro-imaging with two laser frequency combs takes a big step toward the holy grail of real-time label-free biomolecular imaging.
Cell biologists and chemists in Switzerland have revealed how viral DNA moves in human cells. They have developed a new method to generate virus particles containing labeled viral DNA genomes, which has allowed them to visualize, for the first time, single viral genomes in the cytoplasm and the nucleus.
Human fingertips have several types of sensory neurons that are responsible for relaying touch signals to the central nervous system. Scientists have long believed these neurons followed a linear path to the brain with a "labeled-lines" structure. But new research on mouse whiskers reveals a surprise: At the fine scale, the sensory system's wiring diagram doesn't have a set pattern.
Micromachines operate under very different conditions than their macroscale cousins. The high surface-area-to-mass ratio of tiny motors means they require a constant driving force to keep them going. In the past, researchers have relied on asymmetric chemical reactions on the surface of the motors to supply the force. Researchers in Japan have now discovered, however, that two-sided materials aren't necessary to make micromotors move.
During evolution, many plants and organisms have developed mushroom-shaped adhesive structures and organs that allow them to climb walls and grip surfaces. Through observations of these microstructures at speeds of up to 180,000 frames per second, scientists have discovered why the specific shape is advantageous for adhesion.
Researchers have developed a new quantitative method of identifying pollen grains that is certainly nothing to sneeze at. Since the invention of the light microscopes, the classification of pollen and spores has been a highly subjective venture for those who use these tiny particles to study vegetation in their field, palynology. However, the limitations have kept researchers from classifying pollen and spores beyond a general level.
The microscopic technique, developed by researchers at Queen Mary Univ. of London, represents a major advance for cell biologists as it will allow them to investigate structures deep inside the cell, such as viruses, bacteria and parts of the nucleus in depth.
With high-tech optical tools and sophisticated mathematics, Rice Univ. researchers have found a way to pinpoint the location of specific sequences along single strands of DNA, a technique that could someday help diagnose genetic diseases. Proof-of-concept experiments in the Rice laboratory of chemist Christy Landes identified DNA sequences as short as 50 nucleotides at room temperature.
Researchers at Massachusetts Institute of Technology, working with partners at NASA, have developed a new concept for a microscope that would use neutrons instead of beams of light or electrons to create high-resolution images. Among other features, neutron-based instruments have the ability to probe inside metal objects to learn details of their internal structure.
Autumn is usually not such a great time for big special effects movies as the summer blockbusters have faded and those for the holiday season have not yet opened. Fall is more often the time for thoughtful films about small subjects, which makes it perfect for the unveiling of a new movie produced by researchers at Lawrence Berkeley National Laboratory.
Scientists at Massachusetts Institute of Technology and the Univ. of Texas at Arlington have developed a new type of microscopy that can image cells through a silicon wafer, allowing them to precisely measure the size and mechanical behavior of cells behind the wafer. The new technology, which relies on near-infrared light, could help scientists learn more about diseased or infected cells as they flow through silicon microfluidic devices.
In a new white paper from Carl Zeiss Microscopy, scientists from DME Nanotechnologie GmbH and Zeiss demonstrate the power of the AFM/SEM combination found in the Zeiss Merlin series microscopes for the analysis of helium ion beam exposed nanostructures.
Inspired by how wireless communication networks use multiple radio frequencies to communicate with multiple users, researchers from the Univ. of California, Los Angeles have developed a new high-speed microscopy technique that is an order of magnitude faster than current fluorescence-imaging technologies.
A team from Queen’s Univ. has found a way to “feel” the surface of silicon molecules at the molecular level. This new “sense of touch” could mean a solution to the long-standing problem of producing clear images of silicon surfaces with a scanning tunneling microscope. Closely examining silicon surfaces has become increasingly important over the years as nearly all microelectronic devices are made from silicon-containing microchips.
Watching a plant grow and develop roots can be a long and tiresome process, but watching this process closely can reveal what happens to a genetically modified organism. A recently developed system from IntelLiDrives and the Univ. of Wisconsin-Madison uses robotic cameras and computerized motion control systems to make this process easier.
On Tuesday, Olympus America debuted a new functional brain mapping and high-speed physiology multiphoton system, the Olympus FluoView FVMPE-RS. This system enables high-precision, ultra-fast scanning and stimulation, allowing researchers to see deep within specimens and take measurements at high speeds under demanding conditions.
Your smartphone now can see what the naked eye cannot: A single virus and bits of material less than one-thousandth of the width of a human hair. A team at the Univ. of California, Los Angeles has created a portable smartphone attachment that can be used to perform sophisticated field testing to detect viruses and bacteria without the need for bulky and expensive microscopes and lab equipment. The device weighs less than half a pound.
Asylum Research has announced the release of the new GetReal Automated Probe Calibration feature. With one click, GetReal fully calibrates the atomic force microscope (AFM) probe sensitivity and spring constant, enabling more consistent, more accurate results.
JEOL has introduced a new scanning electron microscope (SEM) with expanded pressure range, large specimen chamber and high resolution for imaging and characterizing a wide variety of sample types and sizes. The JSM-IT300LV is the latest addition to JEOL's series of tungsten low vacuum SEMs.
Developers at Lawrence Livermore National Laboratory have introduced the Movie Mode Dynamic Transmission Electron Microscope (MM-DTEM), which can capture an in situ multiframe movie that reveals a complex sequence of nanoscale events with frame rates over 100,000 times faster than those of conventional techniques. MM-DTEM is based on a TEM that has been modified to include two pulsed lasers, the sample drive laser and the cathode laser.
Imaging of live, large-scale biological specimens is an important application for biological research. This is typically done using fluorescence microscopes that must achieve high resolution and clarity without damaging the specimen. The Lightsheet Z.1 fluorescence microscopy system from Carl Zeiss Microscopy LLC is specifically designed to protect the health and integrity of specimens.
Scanning probe technologies such as atomic force microscopes (AFMs) return spatial maps with atomic-scale detail; but until now, no equivalently accessible tool to investigate chemical and physical properties at such a length scale was available. Scientists at Lawrence Berkeley National Laboratory have overcome this challenge by developing a tool to perform optical spectroscopy with a spatial resolution less than 10 nm, two orders of magnitude better than is possible with current technologies.
High-temperature testing of micro- and nanoscale materials has been limited by deleterious effects like oxidation or thermal drift. Despite this constraint on temperature level, the demand for this type of analysis means that heating stages are optional on many commercially available nanoindentation systems. Nanomechanics Inc. has improved available options with the introduction of the InSEM HT, which, for the first time, allows materials testing under load up to 500 C in an electron microscope or other vacuum environment.
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