New UCLA research indicates that lost memories can be restored. The findings offer some hope for patients in the early stages of Alzheimer’s disease. For decades, most neuroscientists have believed that memories are stored at the synapsesm which are destroyed by Alzheimer’s disease. The new study provides evidence contradicting the idea that long-term memory is stored at synapses.
Researchers at Swinburne University of Technology have discovered an instability in gold nanoparticles that is critical for their application in future technology. Gold nanorods are important building blocks for future applications in solar cells, cancer therapy and optical circuitry.
Univ. of California, Los Angeles researchers have developed a lens-free microscope that can be used to detect the presence of cancer or other cell-level abnormalities with the same accuracy as larger and more expensive optical microscopes. The invention could lead to less expensive and more portable technology for performing common examinations of tissue, blood and other biomedical specimens.
More than 90% of cancer-related deaths are caused by the spread of cancer cells from their primary tumor site to other areas of the body. A new study has identified how one important gene helps cancer cells break free from the primary tumor.
Mistletoe hanging in doorways announces that the holidays are just around the corner. For some people, however, the symbolic plant might one day represent more than a kiss at Christmas time: It may mean better liver health. Researchers have found that a compound produced by a particular variety of the plant can help fight obesity-related liver disease in mice.
Newly published research provides the first demonstration of how a genetic mutation associated with a common form of albinism leads to the lack of melanin pigments that characterizes the condition. About 1 in 40,000 people worldwide have type 2 oculocutaneous albinism, which has symptoms of unusually light hair and skin coloration, vision problems and reduced protection from sunlight-related skin or eye cancers.
A Yale Univ. laboratory has crafted the first synthetic molecules that have both the targeting and response functions of antibodies. The new molecules attach themselves simultaneously to disease cells and disease-fighting cells. The result is a highly targeted immune response, similar to the action of natural human antibodies.
Around 400 BC, Hippocrates was among the first people in recorded history to postulate the brain as the seat of sensation and intelligence. Yet only in the last 100 years have we identified, and closely studied, its key building block: the neuron. A highly specialized cell found in all but the simplest animals, like sponges, the neuron is one of the keys to understanding the brain.
The bionic age is no longer the workings of a far-fetched sci-fi movie; it’s here, now. We have experienced the first bionic eye and limbs. These technologies merge human capabilities with machines. They transform how we live, and who we are. They are improving quality of life. And there’s perhaps no greater example than R&D Magazine’s Innovator of the Year Prof. Hugh Herr.
Rice Univ. scientists have detected at least three instances of cross-species mating that likely influenced the evolutionary paths of “old world” mice, two in recent times and one in the distant past. The researchers think these instances of introgressive hybridization are only the first of many needles waiting to be found in a very large genetic haystack.
Lawrence Livermore National Laboratory researchers in conjunction with collaborators at Univ. of California, Los Angeles have found that some cells build intracellular compartments that allow the cell to store metals and maintain equilibrium. Nearly 40% of all proteins require metal ions such as zinc, copper, manganese or iron for activity.
In one of the most comprehensive laboratory studies of its kind, Rice Univ. scientists traced the uptake and accumulation of quantum dot nanoparticles from water to plant roots, plant leaves and leaf-eating caterpillars. The study found that nanoparticle accumulation in both plants and animals varied significantly depending upon the type of surface coating applied to the particles.
A new study from Massachusetts Institute of Technology implicates a family of RNA-binding proteins in the regulation of cancer, particularly in a subtype of breast cancer. These proteins, known as Musashi proteins, can force cells into a state associated with increased proliferation.
When someone you know is wearing an unfamiliar hat, you might not recognize them. Georgia Institute of Technology researchers are using just such a disguise to sneak biomaterials containing peptide signaling molecules into living animals. When the disguised peptides are needed to launch biological processes, the researchers shine ultraviolet light onto the molecules through the skin, causing the "hat" structures to come off.
Squid, what is it good for? You can eat it and you can make ink or dye from it, and now a Penn State Univ. team of researchers is using it to make a thermoplastic that can be used in 3-D printing. The team looked at the protein complex that exists in the squid ring teeth (SRT). The naturally made material is a thermoplastic, but obtaining it requires a large amount of effort and many squid.
A species of small fish uses a homemade coral-scented cologne to hide from predators, a new study has shown, providing the first evidence of chemical camouflage from diet in fish. Filefish evade predators by feeding on their home corals and emitting an odor that makes them invisible to the noses of predators, the study found.
Where did the songbird get its song? What branch of the bird family tree is closer to the flamingo: the heron or the sparrow? These questions seem simple, but are actually difficult for geneticists to answer. A new, sophisticated statistical technique developed by researchers can help researchers construct more accurate species trees detailing the lineage of genes and the relationships between species.
In a triumph for cell biology, researchers have assembled the first high-resolution, 3-D maps of entire folded genomes and found a structural basis for gene regulation—a kind of “genomic origami” that allows the same genome to produce different types of cells. The research appears online in Cell.
In a triumph for cell biology, researchers have assembled the first high-resolution, 3-D maps of entire folded genomes and found a structural basis for gene regulation -- a kind of "genomic origami" that allows the same genome to produce different types of cells.
Growing resistance to malaria drugs in Southeast Asia is caused by a single mutated gene inside the disease-causing Plasmodium falciparum parasite. This finding provides public health officials around the world with a way to look for pockets of emerging resistance and potentially eliminate them before they spread.
Researchers for the first time have developed a method to track through the human body the movement of polycyclic aromatic hydrocarbons, or PAHs, as extraordinarily tiny amounts of these potential carcinogens are biologically processed and eliminated.
Researchers have devised a way to replace the knee’s protective lining, called the meniscus, using a personalized 3D-printed implant, or scaffold, infused with human growth factors that prompt the body to regenerate the lining on its own. The therapy, successfully tested in sheep, could provide the first effective and long-lasting repair of damaged menisci.
It may be possible to develop a simple blood test that, by detecting changes in the zinc in our bodies, could help to diagnose breast cancer early.
Scientists in a lab used a powerful laser to re-create what might have been the original spark of life on Earth. The researchers zapped clay and a chemical soup with the laser to simulate the energy of a speeding asteroid smashing into the planet.
Scientists from the Spanish National Cancer Research Centre (CNIO), have developed a method for producing biological crystals that has allowed scientists to observe— for the first time— DNA double chain breaks.