Researchers at Yale Univ. have joined forces with a leading 3-D biology company, Organovo, to develop 3-D printed tissues for transplant research. As the number of donors for vital tissue and organ transplants decreases worldwide and the demand for transplants increases, 3-D bioprinting technology offers a solution to a long-standing and growing problem.
In a study in Neuron, scientists describe a new high data-rate, low-power wireless brain sensor. The technology is designed to enable neuroscience research that cannot be accomplished with current sensors that tether subjects with cabled connections. Experiments in the paper confirm that new capability.
A groundbreaking research project by the GW4 Alliance aims to clean up water from a Cornish tin mine, using algae to harvest the precious heavy metals and produce biofuel at the same time. GW4 brings together the South West and Wales’ four leading, research-intensive universities: Bath, Bristol, Cardiff and Exeter.
An international team of researchers have caught a light-sensitive biomolecule at work using an x-ray laser. Their new study proves that high speed x-ray lasers can capture the fast dynamics of biomolecules in ultra slow-motion, revealing subtle processes with unprecedented clarity.
The electric eel—the scaleless Amazonian fish that can deliver an electrical jolt strong enough to knock down a full-grown horse—possesses an electroshock system uncannily similar to a Taser. That’s the conclusion of a nine-month study of the way in which the electric eel uses high-voltage electrical discharges to locate and incapacitate its prey.
A team led by Florida State Univ. researchers has identified DNA elements in maize that could affect the expression of hundreds or thousands of genes. The team wanted to know if certain DNA structures such as the four-strand G-quadruplex (G4) DNA might exist throughout the genetic material of maize.
Take two poisonous mushrooms, and call me in the morning. While no doctor would ever write this prescription, toxic fungi may hold the secrets to tackling deadly diseases. A team of Michigan State Univ. scientists has discovered an enzyme that is the key to the lethal potency of poisonous mushrooms.
Current asthma treatments can alleviate wheezing, coughing and other symptoms felt by millions of Americans every year, but they don’t get to the root cause of the condition. Now, for the first time, scientists are reporting a new approach to defeating asthma by targeting the trigger—the allergen—before it can spark an attack. They describe their new compound, which they tested on rats, in the Journal of Medicinal Chemistry.
Geckos, found in places with warm climates, have fascinated people for hundreds of years. Scientists have been especially intrigued by these lizards, and have studied a variety of features such as the adhesive toe pads on the underside of gecko feet with which geckos attach to surfaces with remarkable strength.
SLAS2015 takes place Feb. 7-11 in Washington, DC. Programmed especially for scientists and researchers looking to leverage the latest in technology. Best-in-class education, innovation and networking at the intersection of science and technology.
The rapid evolution of HIV, which has allowed the virus to develop resistance to patients' natural immunity, is at the same time slowing the virus's ability to cause AIDS. The Oxford Univ.-led study also indicates that people infected by HIV are likely to progress to AIDS more slowly—in other words the virus becomes less “virulent”—because of widespread access to antiretroviral therapy (ART).
New research from Rice Univ. and the Univ. of Texas MD Anderson Cancer Center shows how ovarian tumors co-opt a specific type of adult stem cell from abdominal tissues to fuel their growth. The research, published online in Cancer Research, suggests a new way to target aggressive ovarian cancers by disrupting the metabolic processes that allow them to thrive.
Biological engineers have created a new computer model that allows them to design the most complex 3-D DNA shapes ever produced, including rings, bowls and geometric structures such as icosahedrons that resemble viral particles. This design program could allow researchers to build DNA scaffolds to anchor arrays of proteins and light-sensitive molecules called chromophores that mimic the photosynthetic proteins found in plant cells.
IBM has engineered a way for everyone to join the fight against Ebola—by donating processing time on their personal computers, phones or tablets to researchers. IBM has teamed with scientists at Scripps Research Institute in southern California on a project that aims to combine the power of thousands of small computers, to each attack tiny pieces of a larger medical puzzle that might otherwise require a supercomputer to solve.
New research from North Carolina State Univ. and the Univ. of Minnesota shows the majority of consumers will accept the presence of nanotechnology or genetic modification (GM) technology in foods—but only if the technology enhances the nutrition or improves the safety of the food. The researchers conducted a nationally representative survey of 1,117 U.S. consumers.
Los Alamos National Laboratory has released an updated version of powerful bioinformatics software that is now capable of identifying DNA from viruses and all parts of the Tree of Life—putting diverse problems such as identifying pathogen-caused diseases, selection of therapeutic targets for cancer treatment and optimizing yields of algae farms within relatively easy reach for health care professionals, researchers and others.
The house mouse, stickleback fish and honey bee appear to have little in common, but at the genetic level these creatures respond in strikingly similar ways to danger, researchers report. When any of these animals confronts an intruder, the researchers found, many of the same genes and brain gene networks gear up or down in response.
Two years ago, researchers at the Joint BioEnergy Institute engineered E. coli bacteria to convert glucose into significant quantities of methyl ketones, a class of chemical compounds primarily used for fragrances and flavors, but highly promising as clean, green and renewable blending agents for diesel fuel. Now, after further genetic modifications, they have managed to dramatically boost the E.coli’s methyl ketone production 160-fold.
Researchers can now explore viruses, bacteria and components of the human body in more detail than ever before with software developed at The Scripps Research Institute. In a study published online in Nature Methods, the researchers demonstrated how the software, called cellPACK, can be used to model viruses such as HIV.
The presence of an immune-suppressing protein in non-cancerous immune cells may predict how patients with different types of cancer respond to treatment, a multi-center phase I study using an investigational immune therapy drug has found. The trial included patients with melanoma or cancers of the lung, kidney, colon, GI tract, or head and neck, whose tumors were evaluated for PD-L1 expression by a novel assay.
Toxoplasma gondii is a common parasite often spread by cats. Most people who are infected in Europe or North America show no symptoms at all, and only a few suffer from encephalitis or ocular toxoplasmosis, which can cause blindness. However, in South America, toxoplasmosis is associated with much more severe symptoms.
In recent years it has been established that copper plays an essential role in the health of the human brain. Improper copper oxidation has been linked to several neurological disorders. Copper has also been identified as a critical ingredient in the enzymes that activate the brain’s neurotransmitters in response to stimuli. Now, a new study has shown that proper copper levels are also essential to the health of the brain at rest.
Many older people silently harbor a blood "pre-cancer"—a gene mutation acquired during their lifetime that could start them on the path to leukemia, lymphoma or other blood disease, scientists have discovered. It opens a new frontier on early detection and possibly someday preventing these cancers, which become more common with age.
An experimental Ebola vaccine appears safe and triggered signs of immune protection in the first 20 volunteers to test it, U.S. researchers reported. The vaccine is designed to spur the immune system's production of anti-Ebola antibodies, and people developed them within four weeks of getting the shots at the National Institutes of Health.
A team of scientists from Arizona State Univ.’s Biodesign Institute and IBM’s T.J. Watson Research Center have developed a prototype DNA reader that could make whole genome profiling an everyday practice in medicine. Such technology could help usher in the age of personalized medicine, where information from an individual’s complete DNA and protein profiles could be used to design treatments specific to their individual makeup.