Advertisement
Biology
Subscribe to Biology

The Lead

Environmental “tipping points” key to predicting extinctions

November 25, 2014 11:35 am | by Tracey Peake, North Carolina State Univ. | News | Comments

Researchers from North Carolina State Univ. have created a model that mimics how differently adapted populations may respond to rapid climate change. Their findings demonstrate that depending on a population’s adaptive strategy, even tiny changes in climate variability can create a “tipping point” that sends the population into extinction.

Angiogenesis drug could provide treatment for TB

November 25, 2014 9:27 am | by Karl Bates, Duke Univ. | News | Comments

The body responds to tuberculosis infection by locking the bacterial offenders into tiny...

Pain in a dish

November 25, 2014 9:11 am | by Harvard Stem Cell Institute | News | Comments

After more than six years of intensive effort, and repeated failures that made the quest at...

Wireless electronic implants stop staph

November 25, 2014 8:41 am | by Kim Thurier, Tufts Univ. | News | Comments

Researchers at Tufts Univ., in collaboration with a team at the Univ. of Illinois at Urbana-...

View Sample

FREE Email Newsletter

Device could make large biological circuits practical

November 25, 2014 7:59 am | by David L. Chandler, MIT News Office | News | Comments

Researchers have made great progress in recent years in the design and creation of biological circuits: systems that, like electronic circuits, can take a number of different inputs and deliver a particular kind of output. But while individual components of such biological circuits can have precise and predictable responses, those outcomes become less predictable as more such elements are combined.

Brain’s reaction to virtual reality

November 25, 2014 7:42 am | by Stuart Wolpert, Univ. of California, Los Angeles | News | Comments

Univ. of California, Los Angeles neurophysicists have found that space-mapping neurons in the brain react differently to virtual reality than they do to real-world environments. Their findings could be significant for people who use virtual reality for gaming, military, commercial, scientific or other purposes.

Cell’s skeleton is never still

November 24, 2014 11:23 am | by Mike Williams, Rice Univ. | News | Comments

New computer models that show how microtubules age are the first to match experimental results and help explain the dynamic processes behind an essential component of every living cell, according to Rice Univ. scientists. The results could help scientists fine-tune medications that manipulate microtubules to treat cancer and other diseases. 

Advertisement

Nanoparticles infiltrate, kill cancer cells from within

November 24, 2014 11:06 am | by Melanie Titanic-Schefft, Univ. of Cincinnati | News | Comments

Conventional treatment seeks to eradicate cancer cells by drugs and therapy delivered from outside the cell, which may also affect (and potentially harm) nearby normal cells. In contrast to conventional cancer therapy, a Univ. of Cincinnati team has developed several novel designs for iron-oxide based nanoparticles that detect, diagnose and destroy cancer cells using photo-thermal therapy (PTT).

Bee brains offer insights into how human memories form

November 24, 2014 9:46 am | by Univ. of Queensland | News | Comments

Scientists have discovered that genes switch off as memories are being formed, allowing for new connections between nerve cells. The discovery could eventually lead to a key for treating conditions such as autism and dementia. Researchers studying honeybees during learning activities have shown that memory management in the bee brain is controlled by small genetic elements called microRNAs that help regulate gene expression.

Life’s extremists may be an untapped source of antibacterial drugs

November 24, 2014 9:29 am | by David Salisbury, Vanderbilt Univ. | News | Comments

One of the most mysterious forms of life may turn out to be a rich and untapped source of antibacterial drugs. The mysterious life form is Archaea, a family of single-celled organisms that thrive in environments like boiling hydrothermal pools and smoking deep sea vents which are too extreme for most other species to survive.

Robotics meet x-ray laser in cutting-edge biology studies

November 24, 2014 8:31 am | by SLAC Office of Communications | News | Comments

Scientists at SLAC National Accelerator Laboratory are combining the speed and precision of robots with one of the brightest x-ray lasers on the planet for pioneering studies of proteins important to biology and drug discovery. The new system uses robotics and other automated components to precisely maneuver delicate samples for study with the x-ray laser pulses at SLAC’s Linac Coherent Light Source.

For important tumor-suppressing protein, context is key

November 24, 2014 8:19 am | by Dan Krotz, Lawrence Berkeley National Laboratory | News | Comments

Scientists from Lawrence Berkeley National Laboratory have learned new details about how an important tumor-suppressing protein, called p53, binds to the human genome. As with many things in life, they found that context makes a big difference. The researchers mapped the places where p53 binds to the genome in a human cancer cell line.

Advertisement

Model evaluates where bioenergy crops grow best

November 24, 2014 7:59 am | by Liz Ahlberg, Physical Sciences Editor, Univ. of Illinois, Urbana-Champaign | News | Comments

Farmers interested in bioenergy crops now have a resource to help them determine which kind of bioenergy crop would grow best in their regions and what kind of harvest to expect. Researchers at the Univ. of Illinois have published a study identifying yield zones for three major bioenergy crops.

How mutant gene causes deafness

November 21, 2014 9:47 am | by The Scripps Research Institute | News | Comments

Scientists at The Scripps Research Institute (TSRI) have discovered how one gene is essential to hearing, uncovering a cause of deafness and suggesting new avenues for therapies. The new study, published in Neuron, shows how mutations in a gene called Tmie can cause deafness from birth. Underlining the critical nature of their findings, researchers were able to reintroduce the gene in mice and restore the process underpinning hearing.

Quantum mechanical calculations reveal the hidden states of enzyme active sites

November 21, 2014 8:37 am | by Princeton Univ. | News | Comments

Enzymes carry out fundamental biological processes such as photosynthesis, nitrogen fixation and respiration, with the help of clusters of metal atoms as "active" sites. But scientists lack basic information about their function because the states thought to be critical to their chemical abilities cannot be experimentally observed.

Biomarker could provide early warning of kidney disease in cats

November 21, 2014 8:27 am | by David Stauth, Oregon State Univ. | News | Comments

Researchers from Oregon State Univ. and other institutions have developed a new biomarker called “SDMA” that can provide earlier identification of chronic kidney disease in cats, which is one of the leading causes of their death. A new test based on this biomarker, when commercialized, should help pet owners and their veterinarians watch for this problem through periodic checkups, and treat it with diet or other therapies.

Deep-Earth carbon offers clues about origin of life

November 21, 2014 7:53 am | by Jill Rosen, Johns Hopkins Univ. | News | Comments

New findings by a Johns Hopkins Univ.-led team reveal long unknown details about carbon deep beneath the Earth’s surface and suggest ways this subterranean carbon might have influenced the history of life on the planet. The team also developed a new, related theory about how diamonds form in the Earth’s mantle.

Advertisement

Researchers create first inhibitor for enzyme linked to certain cancers

November 21, 2014 7:49 am | by Univ. of California, Irvine | News | Comments

Recent studies showing acid ceramidase (AC) to be upregulated in melanoma, lung and prostate cancers have made the enzyme a desired target for novel synthetic inhibitor compounds. In Angewandte Chemie, scientists with the Univ. of California, Irvine School of Medicine and the Italian Institute of Technology describe the very first class of AC inhibitors that may aid in the efficacy of chemotherapies.

Unique sense of “touch” gives a prolific bacterium its ability to infect anything

November 20, 2014 8:49 am | by Morgan Kelly, Office of Communications, Princeton Univ. | Videos | Comments

New research has found that one of the world's most prolific bacteria manages to afflict humans, animals and even plants by way of a mechanism not before seen in any infectious microorganism—a sense of touch. This unique ability helps make the bacteria Pseudomonas aeruginosa ubiquitous, but it also might leave these antibiotic-resistant organisms vulnerable to a new form of treatment.

Many older brains have plasticity, but in a different place

November 20, 2014 8:38 am | by David Orenstein, Brown Univ. | News | Comments

A widely presumed problem of aging is that the brain becomes less flexible or plastic, and that learning may therefore become more difficult. A new study led by Brown Univ. researchers contradicts that notion with a finding that plasticity did occur in seniors who learned a task well, but it occurred in a different part of the brain than in younger people.

Spiraling light, nanoparticles and insights into life’s structure

November 20, 2014 8:12 am | by Nicole Casal Moore, Univ. of Michigan | News | Comments

As hands come in left and right versions that are mirror images of each other, so do the amino acids and sugars within us. But unlike hands, only the left-oriented amino acids and the right-oriented sugars ever make into life as we know it. Scientists know the other varieties exist because when they synthesize these amino acids and sugars in a laboratory, roughly equal numbers of left- and right-facing arrangements form.

Immune system surprise hints at new strategy for fighting HIV

November 19, 2014 10:53 am | by Bill Hathaway, Yale Univ. | News | Comments

The discovery of the innate immunity system’s role in mobilizing the body’s defenses against invading microorganisms has been long studied at Yale Univ. Now in Nature Immunology, Yale researchers have discovered a surprising twist to the story that may open a new avenue in the fight against HIV.

Biochemists build largest synthetic molecular “cage” ever

November 19, 2014 10:26 am | by Stuart Wolpert, Univ. of California, Los Angeles | News | Comments

Univ. of California, Los Angeles biochemists have created the largest-ever protein that self-assembles into a molecular “cage.” The research could lead to synthetic vaccines that protect people from the flu, HIV and other diseases. At a size hundreds of times smaller than a human cell, it also could lead to new methods of delivering pharmaceuticals inside of cells, or to the creation of new nanoscale materials.

X-ray laser brings key cell structures into focus

November 19, 2014 9:07 am | by SLAC Office of Communications | News | Comments

Scientists have made high-resolution x-ray laser images of an intact cellular structure much faster and more efficiently than ever possible before. The results are an important step toward atomic-scale imaging of intact biological particles, including viruses and bacteria. The technique was demonstrated at the Linac Coherent Light Source at the SLAC National Accelerator Laboratory.

Computer model sets new precedent in drug discovery

November 19, 2014 8:52 am | by Kat J. McAlpine, Wyss Institute for Biologically Inspired Engineering | Videos | Comments

A major challenge faced by the pharmaceutical industry has been how to rationally design and select protein molecules to create effective biologic drug therapies while reducing unintended side effects—a challenge that has largely been addressed through costly guess–and–check experiments. Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard Univ. offer a new approach.

Hormone points to potential treatment for metabolic disorders

November 19, 2014 8:13 am | by Laura Williams, Univ. of Michigan | News | Comments

Researchers at the Univ. of Michigan have discovered how a previously unknown hormone serves as a messenger from fat cells to the liver and are investigating the potential of developing a new treatment for metabolic disorders. Jiandie Lin of the Life Sciences Institute described how in mice the hormone, NRG4, is secreted by so-called brown fat cells and communicates with the liver to regulate the conversion of sugar into fat.

Paramecia need Newton for navigation

November 19, 2014 7:36 am | by Kevin Stacey, Brown Univ. | Videos | Comments

For such humble creatures, single-celled paramecia have remarkable sensory systems. Give them a sharp jab on the nose, they back up and swim away. Jab them in the behind, they speed up their swimming to escape. But according to new research, when paramecia encounter flat surfaces, they’re at the mercy of the laws of physics.

Study will test survivors' blood to treat Ebola

November 18, 2014 11:00 pm | by Marilynn Marchione - AP Chief Medical Writer - Associated Press | News | Comments

A coalition of companies and aid groups announced plans Tuesday to test experimental drugs and collect blood plasma from Ebola survivors to treat new victims of the disease in West Africa. Plasma from survivors contains antibodies, substances the immune system makes to fight the virus.

Scientists reveal weak spots in Ebola’s defenses

November 18, 2014 9:27 am | by The Scripps Research Institute | News | Comments

Scientists at The Scripps Research Institute have identified weak spots on the surface of Ebola virus that are targeted by the antibodies in ZMapp, the experimental drug cocktail administered to several patients during the recent Ebola outbreak. The study provides a revealing 3-D picture of how the ZMapp antibodies bind to Ebola virus.

X
You may login with either your assigned username or your e-mail address.
The password field is case sensitive.
Loading