Zebrafish with very weak muscles helped scientists decode the elusive genetic mutation responsible for Native American myopathy, a rare, hereditary muscle disease that afflicts Native Americans in North Carolina. Scientists originally identified the gene in mutant zebrafish that exhibited severe muscle weakness. The responsible gene encodes for a muscle protein called Stac3.
High-performance thermoelectric materials that convert waste heat to electricity could one day be a source of more sustainable power. But they need to be a lot more efficient before they could be effective on a broad scale in places like power plants or military bases, researchers say. A University of Michigan researcher has taken a step toward that goal.
Health care spending is much higher for older Americans than for younger adults and children, on average, and analysts have said that increasing spending leads to longer life expectancy. But new research from the University of Michigan indicates that aging populations could view things differently.
You're standing near an airport luggage carousel and your bag emerges on the conveyor belt, prompting you to spring into action. How does your brain make the shift from passively waiting to taking action when your bag appears? A new study from investigators at the University of Michigan and Eli Lilly may reveal the brain's "switch" for new behavior.
Engineering researchers at the University of Michigan have demonstrated a paradigm-shifting "polariton" laser that's fueled not by light, but by electricity. Polaritons are particles that are part light, and part matter. The new device requires at least 1,000 times less energy to operate, compared with a conventional laser.
Most Michigan and Pennsylvania residents say fracking is good for the economy, but have concerns about chemicals used and other environmental risks, according to a University of Michigan survey. Fracking is the common term for hydraulic fracturing, which involves injecting a mixture of water, sand, and chemicals deep into the ground through encased wells at high pressure to create and expand fractures in the shale rock.
Leading nanoscientists created beautiful, tiled patterns with flat nanocrystals, but they were left with a mystery: Why did some sets of crystals arrange themselves in an alternating, herringbone style? To find out, they turned to experts in computer simulation at the University of Michigan and the Massachusetts Institute of Technology.
An international team of physicists has found the first direct evidence of pear-shaped nuclei in exotic atoms. The findings could advance the search for a new fundamental force in nature that could explain why the Big Bang created more matter than antimatter—a pivotal imbalance in the history of everything.
The human body contains trillions of cells, all derived from a single cell. That single cell contains all the genetic information needed to develop into a human, and passes identical copies of that information to each new cell as it divides into the many diverse types of cells. If each cell is genetically identical, however, how does it grow to be a skin, blood, nerve, bone, or other type of cell?
Thermoelectric materials can be used to turn waste heat into electricity or to provide refrigeration without any liquid coolants, and a research team from the University of Michigan has found a way to nearly double the efficiency of a particular class of them that's made with organic semiconductors.
Cancer cells are wily, well-traveled adversaries, constantly side-stepping treatments to stop their spread. But, for the first time, scientists at the University of Michigan have decoded the molecular chatter that ramps certain cancer cells into overdrive and can cause tumors to metastasize throughout the body.
Long-term exposure to air pollution may be linked to heart attacks and strokes by speeding up atherosclerosis, or "hardening of the arteries," according to a University of Michigan public health researcher and colleagues from across the U.S.
Using a new laboratory geochemical technique to analyze heavy isotopes of carbon and oxygen in fossil snail shells, scientists have gained insights into an abrupt climate shift that transformed the planet nearly 34 million years ago. At that time, the Earth switched from a warm and high-carbon dioxide "greenhouse" state to the lower-carbon dioxide, variable climate of the modern "icehouse" world.
The explosive popularity of wireless devices is increasingly clogging the airwaves, resulting in dropped calls, wasted bandwidth, and botched connections. New software, called GapSense, being developed at the University of Michigan works like a stoplight to control the traffic and dramatically reduce interference.
Deep inside your brain, a legion of stem cells lies ready to turn into new brain and nerve cells whenever and wherever you need them most. But what happens to the garbage within cells that keeps them in a stem-cell state. Years of mouse research has allowed researchers at the University of Michigan to discover how autophagy keeps neural stem cells ready to replace damaged brain and nerve cells.
In a development that could make the advanced form of secure communications known as quantum cryptography more practical, University of Michigan researchers have demonstrated a simpler, more efficient single-photon emitter that can be made using traditional semiconductor processing techniques.
One of the major obstacles to growing new organs—replacement hearts, lungs, and kidneys—is the difficulty researchers face in building blood vessels that keep the tissues alive, but new findings from the University of Michigan could help overcome this roadblock.
Wouldn't it be convenient if you could reverse the rusting of your car by shining a bright light on it? It turns out that this concept works for undoing oxidation on copper nanoparticles, and it could lead to an environmentally friendly production process for an important industrial chemical, University of Michigan engineers have discovered.
Low-energy terahertz radiation could potentially enable doctors to see deep into tissues without the damaging effects of X-rays, or allow security guards to identify chemicals in a package without opening it. But it's been difficult for engineers to make powerful enough systems to accomplish these promising applications. Now an electrical engineering research team at the University of Michigan has developed a laser-powered terahertz source and detector system that transmits with 50 times more power and receives with 30 times more sensitivity than existing technologies.
Semiconducting polymers are an unruly bunch, but University of Michigan engineers have developed a new method for getting them in line that could pave the way for cheaper, greener, "paint-on" plastic electronics.
A common test used to determine mercury exposure from dental amalgam fillings may significantly overestimate the amount of the toxic metal released from fillings, according to University of Michigan researchers. Scientists agree that dental amalgam fillings slowly release mercury vapor into the mouth. But both the amount of mercury released and the question of whether this exposure presents a significant health risk remain controversial.
Running cockroaches start to recover from being shoved sideways before their dawdling nervous system kicks in to tell their legs what to do, researchers have found. These new insights on how biological systems stabilize could one day help engineers design steadier robots and improve doctors' understanding of human gait abnormalities.
Traces of water have been detected within the crystalline structure of mineral samples from the lunar highland upper crust obtained during the Apollo missions, according to a University of Michigan researcher and his colleagues. The lunar highlands are thought to represent the original crust, crystallized from a magma ocean on a mostly molten early moon. The new findings indicate that the early moon was wet and that water there was not substantially lost during the moon's formation.
Ancient carbon trapped in Arctic permafrost is extremely sensitive to sunlight and, if exposed to the surface when long-frozen soils melt and collapse, can release climate-warming carbon dioxide gas into the atmosphere much faster than previously thought.
Researchers at the University of Michigan's Life Sciences Institute have found that amlexanox, an off-patent drug currently prescribed for the treatment of asthma and other uses, also reverses obesity, diabetes, and fatty liver in mice.