Researchers at the Univ. of Michigan have obtained the first 3-D snapshots of the "assembly line" within microorganisms that naturally produces antibiotics and other drugs. Understanding the complete structure and movement within the molecular factory gives investigators a solid blueprint for redesigning the microbial assembly line to produce novel drugs of high medicinal value.
Imaging and mapping of electric fields at radio frequencies (RF) currently requires the use of metallic structures such as dipoles, probes and reference antennas. To make such measurements efficiently, the size of these structures needs to be on the order of the wavelength of the RF fields to be mapped. This poses practical limitations on the smallest features that can be measured.
More Americans view global warming by what they see outside their windows and not scientific evidence, according to a Univ. of Michigan survey. While a majority of Americans still believe that global warming is occurring, the cold and snowy winter of 2014 created more disbelievers, according to the National Surveys on Energy and Environment.
Four major U.S. research universities have formed a technology consortium to improve the way in which educational content is shared across universities and ultimately delivered to students. Unizin will provide a common digital infrastructure that will allow member universities to work together to strengthen their traditional missions of education and research using the most innovative technology available today.
With precarious particles called polaritons that straddle the worlds of light and matter, Univ. of Michigan researchers have demonstrated a new, practical and potentially more efficient way to make a coherent laser-like beam. They have made what's believed to be the first polariton laser that is fueled by electrical current as opposed to light, and also works at room temperature, rather than way below zero.
Inspired by fictional cyborgs like Terminator, a team of researchers at the Univ. of Michigan and the Univ. of Pittsburgh has made the first bionic particles from semiconductors and proteins. These particles recreate the heart of the process that allows plants to turn sunlight into fuel.
When we're strolling down memory lane, our brains recall just as much information while walking as while standing still—findings that contradict the popular science notion that walking hinders one's ability to think. Univ. of Michigan researchers at the School of Kinesiology and the College of Engineering examined how well study participants performed a very complex spatial cognitive task while walking versus standing still.
Microbiologists have recently studied unseen armies of viruses and bacteria as they wage war at hydrothermal vents more than a mile beneath the ocean's surface. They have found that viruses infect bacterial cells to obtain tiny globules of elemental sulfur stored inside the bacterial cells. Instead of stealing this bounty, the viruses force the bacteria to burn their valuable sulfur reserves, then use the unleashed energy to replicate.
The ability to control crystals with light and chemistry could lead to chameleon-style color-changing camouflage for vehicle bodies and other surfaces. Univ. of Michigan researchers discovered a template-free method for growing shaped crystals that allows for changeable structures that could appear as different colors and patterns.
A 32-year study of subarctic forest moths in Finnish Lapland suggests that scientists may be underestimating the impacts of climate change on animals and plants because much of the harm is hidden from view. The study analyzed populations of 80 moth species and found that 90% of them were either stable or increasing throughout the study period, from 1978 to 2009.
New findings challenge the prevailing wisdom about how our body clocks are organized, and suggest that interactions among neurons that govern circadian rhythms are more complex than originally thought. A Univ. of Michigan team looked at the circadian clock neuron network in fruit flies, which is functionally similar to that of mammals, but at only 150 clock neurons is much simpler.
The 3-D virtual reality cadaver floats in space like a hologram on an invisible gurney. Univ. of Michigan 3-D Lab employee Sean Petty stands a few inches away. Petty wears special glasses and pilots a joystick to arbitrarily slice away sections of the cadaver. He enlarges and turns the body for a better view of the detailed anatomy inside.
Inspired by the space physics behind solar flares and the aurora, a team of researchers from the Univ. of Michigan and Princeton Univ. has uncovered a new kind of magnetic behavior that could help make nuclear fusion reactions easier to start.
Univ. of Michigan researchers have learned how to fix a cellular structure called the Golgi that mysteriously becomes fragmented in all Alzheimer's patients and appears to be a major cause of the disease. They say that understanding this mechanism helps decode amyloid plaque formation in the brains of Alzheimer's patients, plaques that kills cells and contributes to memory loss and other Alzheimer's symptoms.
The first room-temperature light detector that can sense the full infrared spectrum has the potential to put heat vision technology into a contact lens. Unlike comparable mid- and far-infrared detectors currently on the market, the detector developed by Univ. of Michigan engineering researchers doesn't need bulky cooling equipment to work.
For people whose hands shake uncontrollably due to a medical condition, just eating can be a frustrating and embarrassing ordeal, enough to keep them from sharing a meal with others. But a small new study conducted at the Univ. of Michigan Health System suggests that a new handheld electronic device can help such patients overcome the hand shakes caused by essential tremor, the most common movement disorder.
An ancient chemical, present for billions of years, appears to have helped proteins function properly since time immemorial. Proteins are the body's workhorses, and like horses they often work in teams. There exists a modern day team of multiple chaperone proteins that help other proteins fold into the complex 3-D shapes they must achieve to function. This is necessary to avert many serious diseases caused when proteins misbehave.
A new study led by the Joint Institute for Strategic Energy Analysis says that the total impact of switching to natural gas depends heavily on leakage of methane during the natural gas life cycle, and suggests that more can be done to reduce methane emissions and to improve measurement tools which help inform policy choices.
In a sort of biological "spooky action at a distance," water in a cell slows down in the tightest confines between proteins and develops the ability to affect other proteins much farther away, Univ. of Michigan researchers have discovered. The finding could provide insights into how and why proteins clump together in diseases such as Alzheimer's and Parkinson's.
A brain stimulation technique that is used to treat tough cases of depression could be considerably improved with a new headpiece designed by Univ. of Michigan engineers. Computer simulations showed that the headpiece—a square array of 64 circular metallic coils—could one day help researchers and doctors hit finer targets in the brain that are twice as deep as they can reach today, and without causing pain.
Structures that put a spin on light reveal tiny amounts of DNA with 50 times better sensitivity than the best current methods, a collaboration between the Univ. of Michigan and Jiangnan Univ. in China has shown. Highly sensitive detection of DNA can help with diagnosing patients, solving crimes and identifying the origins of biological contaminants such as a pathogen in a water supply.
If recent trends continue, auto companies should be able to meet new federal fuel economy standards over the next 12 years, say Univ. of Michigan researchers. A year after the EPA and the National Highway Traffic Safety Administration announced the final standard governing new-vehicle Corporate Average Fuel Economy (CAFE) for model years 2017-2025, CAFE performance has exceeded anticipated levels for 2012 and 2013.
A global hunt for genes that influence heart disease risk has uncovered 157 changes in human DNA that alter the levels of cholesterol and other blood fats—a discovery that could lead to new medications. Each of the changes points to genes that can modify levels of cholesterol and other blood fats and are potential drug targets.
A microfluidic chip developed at the Univ. of Michigan is among the best at capturing elusive circulating tumor cells from blood—and it can support the cells' growth for further analysis. The device, believed to be the first to pair these functions, uses the advanced electronics material graphene oxide. In clinics, such a device could one day help doctors diagnose cancers.
Coal soot shrank the Alpine glaciers in mid-19th-century Europe, according to new findings that show how black carbon alone, even without warmer temperatures, can affect ice and snow cover. The research provides insights into when the so-called Little Ice Age ended and why European glaciers began to retreat decades before global temperatures rose.