A new drug that prompts cancer cells to self-destruct while sparing healthy cells is now entering phase I clinical trials in humans. The drug, called PAC-1, first showed promise in the treatment of pet dogs with spontaneously occurring cancers, and is still in clinical trials in dogs with osteosarcoma.
When exposed to nitrogen fertilizer over a period of years, nitrogen-fixing bacteria called...
Researchers at the Univ. of Illinois at Urbana-Champaign have developed a unique single-step...
Seismic waves are helping scientists to plumb the world’s deepest mystery: the planet’s inner core. Thanks to a novel application of earthquake-reading technology, a research team at the Univ. of Illinois and colleagues at Nanjing Univ. in China have found that the Earth’s inner core has an inner core of its own, which has surprising properties that could reveal information about our planet.
Two new drug compounds appear to be effective in treating endometriosis, a disorder that, like MS, is driven by estrogen and inflammation, scientists report in Science Translational Medicine. The researchers hope to eventually use the new compounds and others like them to treat a variety of disorders linked to estrogen signaling and inflammation.
People who have upbeat outlooks on life have significantly better cardiovascular health, suggests a new study that examined associations between optimism and heart health in more than 5,100 adults. Participants’ cardiovascular health was assessed using seven metrics: blood pressure, body mass index, fasting plasma glucose and serum cholesterol levels, dietary intake, physical activity and tobacco use.
Stroke victims could have more time to seek treatment that could reduce harmful effects on the brain, thanks to tiny blobs of gelatin that could deliver the medication to the brain noninvasively. Univ. of Illinois researchers found that gelatin nanoparticles could be laced with medications for delivery to the brain, and that they could extend the treatment window for when a drug could be effective.
Where did the songbird get its song? What branch of the bird family tree is closer to the flamingo: the heron or the sparrow? These questions seem simple, but are actually difficult for geneticists to answer. A new, sophisticated statistical technique developed by researchers can help researchers construct more accurate species trees detailing the lineage of genes and the relationships between species.
Scientists have created an app that brings molecules to life in a handheld device. Through the app, people can use up to eleven fingers to examine in great detail more than 350 molecules.
Researchers at the Univ. of Illinois at Urbana-Champaign have figured out how to reverse the characteristics of a key bonding material—polyurea—providing an inexpensive alternative for a broad number of applications, such as drug delivery, tissue engineering and packaging.
The house mouse, stickleback fish and honey bee appear to have little in common, but at the genetic level these creatures respond in strikingly similar ways to danger, researchers report. When any of these animals confronts an intruder, the researchers found, many of the same genes and brain gene networks gear up or down in response.
Farmers interested in bioenergy crops now have a resource to help them determine which kind of bioenergy crop would grow best in their regions and what kind of harvest to expect. Researchers at the Univ. of Illinois have published a study identifying yield zones for three major bioenergy crops.
When munched by grazing animals (or mauled by scientists in the laboratory), some herbaceous plants overcompensate, producing more plant matter and becoming more fertile than they otherwise would. Scientists say they now know how these plants accomplish this feat of regeneration. They report their findings in Molecular Ecology.
Tiny, thin microtubes could provide a scaffold for neuron cultures to grow so that researchers can study neural networks, their growth and repair, yielding insights into treatment for degenerative neurological conditions or restoring nerve connections after injury. Researchers created the microtube platform to study neuron growth.
A common perception, especially outside the university classroom, is that teaching and research are two separate domains, with little overlap. That’s not the reality, however, for many Univ. of Illinois faculty. For these faculty members, “there is an active and dynamic link” between the two.
In spite of the broad scientific consensus about its existence, global warming remains a contentious public policy issue. Yet it’s also an issue that requires a public consensus to support policies that might curb or counteract it. According to research, the task of educating the public about climate change might be made easier or more difficult depending on their perception of short-term versus long-term temperature changes.
Astronomers have caught their first glimpse of the invisible magnetic fields that sculpt solar systems. Looking at a bright, nearby baby star and the dust swirling in its cradle, astronomers from the Univ. of Illinois and six collaborating institutions were able to make out the shape of the magnetic field surrounding the star.
Researchers report in Nature that they have made a breakthrough in understanding how a powerful antibiotic agent is made in nature. Their discovery solves a decades-old mystery, and opens up new avenues of research into thousands of similar molecules, many of which are likely to be medically useful.
River beds, where flowing water meets silt, sand and gravel, are critical ecological zones. Yet how water flows in a river with a gravel bed is very different from the traditional model of a sandy river bed, according to a new study that compares their fluid dynamics. The findings establish new parameters for river modeling that better represent reality, with implications for field researchers and water resource managers.
Nanomedicines consisting of nanoparticles for targeted drug delivery to specific tissues and cells offer new solutions for cancer diagnosis and therapy. Understanding the interdependency of physiochemical properties of nanomedicines, in correlation to their biological responses and functions, is crucial for their further development of as cancer-fighters.
When Illinois researchers set out to investigate a method to control how DNA moves through a tiny sequencing device, they didn’t know they were about to witness a display of molecular gymnastics. Fast, accurate and affordable DNA sequencing is the first step toward personalized medicine.
Thermal considerations are rapidly becoming one of the most serious design constraints in microelectronics, especially on submicron scale lengths. A study by researchers from the Univ. of Illinois at Urbana-Champaign has shown that standard thermal models will lead to the wrong answer in a 3-D heat-transfer problem if the dimensions of the heating element are on the order of one micron or smaller.
Scientists have scoured cow rumens and termite guts for microbes that can efficiently break down plant cell walls for the production of next-generation biofuels, but some of the best microbial candidates actually may reside in the human lower intestine, researchers report. Their studyis the first to use biochemical approaches to confirm the hypothesis that microbes in the human gut can digest fiber.
A new analysis suggests the planet can produce much more land-plant biomass than previously thought. The study, reported in Environmental Science and Technology, recalculates the theoretical limit of terrestrial plant productivity, and finds that it is much higher than many current estimates allow.
By combining plasmonics and optical microresonators, researchers at the Univ. of Illinois at Urbana-Champaign have created a new optical amplifier (or laser) design, paving the way for power-on-a-chip applications. The speed of currently available semiconductor electronics is limited to about 10 GHz due to heat generation and interconnects delay time issues.
Univ. of Illinois engineers are bringing a touch of color to glucose monitoring. The researchers developed a new continuous glucose monitoring material that changes color as glucose levels fluctuate, and the wavelength shift is so precise that doctors and patients may be able to use it for automatic insulin dosing—something now possible using current point measurements like test strips.
Gene-based personalized medicine has many possibilities for diagnosis and targeted therapy, but one big bottleneck: the expensive and time-consuming DNA sequencing process. Now, researchers at the Univ. of Illinois at Urbana-Champaign have found that nanopores in the material molybdenum disulfide (MoS2) could sequence DNA more accurately, quickly and inexpensively than anything yet available.
Scientists are searching through a massive collection of 20-million-year-old amber found in the Dominican Republic more than 50 years ago, and the effort is yielding fresh insights into ancient tropical insects and the world they inhabited. When the collection is fully curated, a task that will take many years, it will be the largest unbiased Dominican amber collection in the world, the researchers report.
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