Fabricating precise biomolecular structures at extremely small scales is critical to the progress of nanotechnology. Traditionally this has been accomplished through the use of rubber stamps with tiny features which are covered with molecular inks and then stamped onto substrate surfaces, creating molecular patterns. However, when using this technique at the nanoscale, molecules tend to diffuse on the surface both during and after stamping, blurring the patterns. Now, a team of researchers have turned this "soft lithography" process on its head.
A team of researchers have used surface photochemical reactions to probe the critical role of substrate morphology on self-assembly and ligand environment, determining that molecules on curved surfaces have a greater range of orientations and, as a result, react more slowly than do molecules on flat surfaces.
For years, many scientists had thought that plate tectonics existed nowhere in our solar system but on Earth. Now, a University of California, Los Angeles scientist has discovered that the geological phenomenon, which involves the movement of huge crustal plates beneath a planet's surface, also exists on Mars.
Researchers have come across an unexpected potential use for fluoxetine—commonly known as Prozac—which shows promise as an antiviral agent. Using molecular screening, a California research team found that fluoxetine was a potent inhibitor of replication in viruses found in the gastrointestinal tract. The discovery could provide another tool in treating human enteroviruses that sicken and kill people in the U.S. and around the world.
Researchers in California have recently described a new kind of polymer solar cell that produces energy by absorbing mainly infrared light, not visible light, making the cells nearly 70% transparent to the human eye. The device was made from a photoactive plastic that converts infrared light into an electrical current.
From driftwood traveling down a river to a blood cell flowing through your artery, objects moving in a stream of fluid are mostly thought to passively go with the flow but not disturb it in controllable ways. Researchers at the University of California, Los Angeles have recently found that objects within a confined stream create controllable disturbances that can be used to move mass or heat at high rates, potentially providing simple solutions to performing chemical reactions on particles or cooling microelectronic chips.
The ability to distinguish and isolate rare cells from among a large population of assorted cells has become increasingly important for the early detection of disease and for monitoring disease treatments. A new optical microscope could make the tough task a whole lot easier. It uses photonic time-stretch camera technology and is the world's fastest continuous-running camera.
A team of University of California, Los Angeles researchers has created the most powerful high-performance nanoscale microwave oscillators in the world, a development that could lead to cheaper, more energy-efficient mobile communication devices that deliver much better signal quality.
A groundbreaking new study led by University of California, Los Angeles climate expert Alex Hall shows that climate change will cause temperatures in the Los Angeles region to rise by an average of 4 to 5 F by the middle of this century, tripling the number of extremely hot days in the downtown area and quadrupling the number in the valleys and at high elevations.
University of California, Los Angeles biochemists have mapped the structure of a key protein–RNA complex that is required for the assembly of telomerase, an enzyme important in both cancer and aging. The researchers found that a region at the end of the p65 protein that includes a flexible tail is responsible for bending telomerase's RNA backbone in order to create a scaffold for the assembly of other protein building blocks.
Researchers from Rice University and the University of California, Los Angeles unveiled a new data-encoding scheme that slashes more than 30% of the energy needed to write data onto new memory cards that use phase-change memory—a competitor to flash memory that has big backing from industry heavyweights.
By using a laser microbeam technology called optical tweezers, University of California, Irvine and University of California, Los Angeles researchers have uncovered fundamental properties of a key molecular signaling system involved with development, cancer, and cardiovascular disease.
In a new study, investigators from the University of California, Los Angeles describe how they synthesized polymers to attach to proteins in order to stabilize them during shipping, storage, and other activities. The study findings suggest that these polymers could be useful in stabilizing protein formulations.
The overwhelming majority of proteins and other functional molecules in our bodies display chirality: They can exist in two distinct forms that are mirror images of each other. Seeking out a reason for why biological systems express chiral preferences, researchers used lithography to make achiral triangles with no handedness. Then physical entropic forces took over and scientists were completely surprised.
Online crowd-sourcing—in which a task is presented to the public, who respond, for free, with various solutions and suggestions—has been used to evaluate potential consumer products, develop software algorithms, and solve vexing research and development challenges. But diagnosing infectious diseases?
University of California, Los Angeles researchers and their colleagues have developed a novel screening technology that allows large batches of metal-oxide nanomaterials to be assessed quickly, based on their ability to trigger certain biological responses in cells as a result of their semiconductor properties.
Researchers have taken advantage of cells' physical properties to develop a new instrument that slams cells against a wall of fluid and quickly analyzes the physical response, allowing for the identification of cancer and other cell states without expensive chemical tags.
A newly developed cell phone-based platform lets health workers accurately read diagnostic tests in the field and chart the spread of diseases worldwide.
New research by University of California, Los Angeles biologists could lead to predictions of which plant species will escape extinction from climate change. Droughts are worsening around the world, which poses a great challenge to plants in gardens and forests. Scientists have debated for more than a century how to predict which species are most vulnerable.
Researchers at New York University and the University of California, Los Angeles, developed a method to detect sequence difference in individual DNA molecules by taking nanoscopic pictures of molecules themselves. Using direct molecular recognition, the researchers used nanoparticles to turn DNA molecules into a form of molecular Braille that can be read in the scale of nanometers using an atomic force microscope.
University of California, Los Angeles researchers are now able to peer deep within the world's tiniest structures to create 3D images of individual atoms and their positions. Their research presents a new method for directly measuring the atomic structure of nanomaterials.
Researchers at the University of California, Los Angeles have used a standard LightScribe DVD optical drive to produce electrodes composed of an expanded network of graphene that shows excellent mechanical and electrical properties as well as exceptionally high surface area. These LSG supercapacitors demonstrate high-performance graphene-based electrochemical capacitors that maintain excellent electrochemical attributes under high mechanical stress.
Researchers from the University of California, Los Angeles have developed a new cell phone-based fluorescent imaging and sensing platform that can detect the presence of the bacterium Escherichia coli in food and water.
Researchers at University of California, Los Angeles report a unique way to enhance polymer solar cell performance by building a tandem structure device. The device's architecture has also proven to be widely applicable after the researchers adopted a new material provided by Sumitomo Chemical of Japan, increasing the power conversion efficiency from 8.62% to a new world record of 10.6%.
In a recent study, participants played a video game in which they learned the locations of stores in a virtual city. The study showed that they recalled the locations better also received a painless boost from tiny electrodes buried deep inside their brains. The finding may have uses in treating Alzheimer’s disease.