A multidisciplinary team of scientists from the Univ. of California, Los Angeles and Stanford Univ. has used a naturally occurring nanoparticle called a vault to create a novel drug delivery system that could lead to advances in the treatment of cancer and HIV. Their findings could lead to cancer treatments that are more effective with smaller doses and to therapies that could potentially eradicate the HIV virus.
Imagine watching a procedure performed live through the eyes of the surgeon. That’s exactly what...
Researchers in California have created a nanoscale...
A team led by researchers from the Univ. of...
In pharmaceutical production, identifying enzyme catalysts that help improve the speed and efficiency of the process can be a major boon. Figuring out exactly why a particular enzyme works so well is an altogether different quest. Take the cholesterol-lowering drug simvastatin.
Scientists have published the first study explaining in detail how viruses reprogram the metabolism of the cells they invade to promote continued viral growth within an organism.
The frustrated attempts of a Univ. of California, Los Angeles graduate student to quantify the amount of water draining from Greenland's melting ice sheet led him to devise a new way to measure river flows from outer space, he and his professor report in a new study. The new approach relies exclusively on the measurements of a river's width over time, which can be obtained from freely available satellite imagery.
Flawed but colorful diamonds are among the most sensitive detectors of magnetic fields known today, allowing physicists to explore the minuscule magnetic fields in metals, exotic materials and even human tissue. A team of physicists have now shown that these diamond sensors can measure the tiny magnetic fields in high-temperature superconductors, providing a new tool to probe these much ballyhooed but poorly understood materials.
A team of researchers has developed a material that could help prevent blood clots associated with catheters, heart valves, vascular grafts and other implanted biomedical devices. Blood clots at or near implanted devices are thought to occur when the flow of nitric oxide, a naturally occurring clot-preventing agent generated in the blood vessels, is cut off. When this occurs, the devices can fail.
A diverse team of scientists from Univ. of California, Los Angeles' Jonsson Comprehensive Cancer Center has developed an experimental treatment that eradicates an acute type of leukemia in mice without any detectable toxic side effects. The drug works by blocking two important metabolic pathways that the leukemia cells need to grow and spread.
Working on the cutting edge of a newly emerging area of solar-cell research, Univ. of California, Los Angeles engineers have invented a new process for manufacturing highly efficient photovoltaic materials that shows promise for low-cost industrial production. The new process uses so-called perovskite materials, which in the past few years have significantly advanced scientists' efforts to create the next generation of solar cells.
A team of engineers from the Univ. of California, Los Angeles has developed a smartphone attachment and application to test water for the presence of mercury, a toxic heavy metal. The new platform could significantly reduce the time and cost of the testing, and it could be particularly useful in regions with limited technological resources.
To safely use bacteria in agriculture to help fertilize crops, it is vital to understand the difference between harmful and healthy strains. The bacterial genus Burkholderia, for example, includes dangerous disease-causing pathogens—one species has even been listed as a potential bioterrorist agent—but also many species that are safe and important for plant development.
A new study by researchers at the Univ. of California, Los Angeles and McGill Univ. reveals that the U.S. health care system ranks 22nd out of 27 high-income nations when analyzed for its efficiency of turning dollars spent into extending lives. The study illuminates stark differences in countries' efficiency of spending on health care, and the U.S.'s inferior ranking reflects a high price paid and a low return on investment.
A team of researchers have demonstrated a technique that, by measuring the physical properties of individual cells in body fluids, can diagnose cancer with a high degree of accuracy. The technique, which uses a deformability cytometer to analyze individual cells, could reduce the need for more cumbersome diagnostic procedures and the associated costs, while improving accuracy over current methods.
Univ. of California, Los Angeles chemists, for the first time, have employed magnetic resonance imaging to better measure the temperature of gases inside a catalytic reactor. The research, a major step toward bridging the gap between laboratory studies and industrial catalysis, could help improve the design and environmental impact of catalytic reactors.
Everyone grows older, but scientists don't really understand why. Now a Univ. of California, Los Angeles study has uncovered a biological clock embedded in our genomes that may shed light on why our bodies age and how we can slow the process.
When the "war on cancer" was declared, identifying potential biomarkers that would allow doctors to detect the disease early on was a significant goal. To this day, progress depends on understanding the underlying causes and molecular mechanisms of the disease. In a new study, researchers analyzed the gene-expression profiles of more than 2,000 patients and were able to identify cancer-specific gene signatures for certain cancers.
Univ. of California, Los Angeles chemical engineering researchers have created a new synthetic metabolic pathway for breaking down glucose that could lead to a 50% increase in the production of biofuels. The new pathway is intended to replace the natural metabolic pathway known as glycolysis, a series of chemical reactions that nearly all organisms use to convert sugars into the molecular precursors that cells need.
Inspired by how wireless communication networks use multiple radio frequencies to communicate with multiple users, researchers from the Univ. of California, Los Angeles have developed a new high-speed microscopy technique that is an order of magnitude faster than current fluorescence-imaging technologies.
Imagine an electronic display nearly as clear as a window, or a curtain that illuminates a room, or a smartphone screen that doubles in size, stretching like rubber. Now imagine all of these being made from the same material. Researchers from Univ. of California, Los Angeles have developed a transparent, elastic OLED that could one day make all these possible.
Since the discovery of the Van Allen radiation belts in 1958, space scientists have believed these belts encircling the Earth consist of two doughnut-shaped rings of highly charged particles. In February of 2013, a team of scientists reported the surprising discovery of a previously unknown third radiation ring. In new research, scientists have successfully modeled and explained the unprecedented behavior of this third ring.
Your smartphone now can see what the naked eye cannot: A single virus and bits of material less than one-thousandth of the width of a human hair. A team at the Univ. of California, Los Angeles has created a portable smartphone attachment that can be used to perform sophisticated field testing to detect viruses and bacteria without the need for bulky and expensive microscopes and lab equipment. The device weighs less than half a pound.
A lightweight and field-portable device invented at Univ. of California, Los Angeles that conducts kidney tests and transmits data through a smartphone attachment may significantly reduce the need for frequent office visits by people with diabetes and others with chronic kidney ailments.
In collaboration with teams in China, researchers in California have used the technology of single-cell RNA sequencing to track the genetic development of a human and a mouse embryo at a high level of accuracy. The technique could lead to earlier and more accurate diagnoses of genetic diseases, even when the embryo consists of only eight cells.
A team of researchers at the Univ. of California, Los Angeles have designed a system to encrypt software so that it only allows someone to use a program as intended while preventing any deciphering of the code behind it. This is known in computer science as "software obfuscation," and it is the first time it has been accomplished.
The ultimate dream come true for material scientists is to have the ability to make materials that can take on properties and behaviors to best suit our needs. But scientists first must truly understand the properties of cluster assembly through the individual cluster. Now, material scientists will have greater insight into the organizing principles that allow for the design of nanoscopic materials with specific band gap energy.
The genetic malady known as Fragile X syndrome is the most common cause of inherited autism and intellectual disability. Brain scientists know the gene defect that causes the syndrome and understand the damage it does in misshaping the brain's synapses—the connections between neurons. But how this abnormal shaping of synapses translates into abnormal behavior is unclear. Now, researchers believe they know.
Bacteria on a surface wander around and often organize into highly resilient communities known as biofilms. It turns out that they organize in a rich-get-richer pattern similar to the distribution of wealth in the U.S. economy, according to a new study.
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