Low doses of metformin, a widely used diabetes medication and a gene inhibitor known as BI2536 can successfully halt the growth of late-stage prostate cancer tumors, a Purdue Univ. study finds. Prostate cancer causes the second-highest number of cancer-related deaths in men in the U.S., and methods of treating advanced prostate cancer are limited.
Research probing the complex science behind the formation of "dendrites"...
A new cardboard-robotic toolkit allows children to create custom robots they...
New research findings point toward a class of compounds that could be effective in combating infections caused by enterovirus D68, which has stricken children with serious respiratory infections in the U.S. and elsewhere. The researchers used x-ray crystallography to learn the precise structure of the original strain of EV-D68 on its own and when bound to an anti-viral compound called "pleconaril."
A new catalytic process is able to convert what was once considered biomass waste into lucrative chemical products that can be used in fragrances, flavorings or to create high-octane fuel. A team of researchers from Purdue Univ.'s Center for Direct Catalytic Conversion of Biomass to Biofuels, or C3Bio, has developed a process that uses a chemical catalyst and heat to spur reactions that convert lignin into valuable chemical commodities.
A laboratory at Purdue Univ. provided a critical part of the world's first transistor in 1947—the purified germanium semiconductor—and now researchers here are on the forefront of a new germanium milestone. The team has created the first modern germanium circuit—a complementary metal–oxide–semiconductor (CMOS) device—using germanium as the semiconductor instead of silicon.
Purdue Univ. announced that GE Global Research will invest up to $10 million in a five-year partnership focused on R&D in advanced manufacturing. The GE/Purdue Partnership in Research and Innovation in Advanced Manufacturing will push a new era in manufacturing, promoting technologies that enable the digitization, decentralization and democratization of manufacturing to lower cost, improve speed and drive innovation.
A new electrode design for lithium-ion batteries has been shown to potentially reduce the charging time from hours to minutes by replacing the conventional graphite electrode with a network of tin-oxide nanoparticles. Batteries have two electrodes, called an anode and a cathode. The anodes in most of today's lithium-ion batteries are made of graphite.
Researchers at Nano-Meta Technologies Inc. have shown how to overcome key limitations of a material that could enable the magnetic storage industry to achieve data-recording densities far beyond today's computers. The new technology could make it possible to record data on an unprecedented small scale using tiny "nanoantennas" and to increase the amount of data that can be stored on a standard magnetic disk by 10 to 100 times.
Researches have uncovered "smoking-gun" evidence to confirm the workings of an emerging class of materials that could make possible "spintronic" devices and practical quantum computers far more powerful than today's technologies. The materials are called topological insulators.
Researchers have demonstrated a new process to convert all biomass into liquid fuel, and the method could make possible mobile processing plants. The researchers at Purdue Univ. filed a patent application on the concept in 2008 and have now demonstrated that it works in laboratory experiments.
Researchers led by David Thompson, president of Aten Biotherapeutics and a professor in Purdue's Department of Chemistry, are developing controlled-release imaging agents that allow for a longer, safer imaging session.
What began as research into a method to strengthen metals has led to the discovery of a new technique that uses a pulsing laser to create synthetic nanodiamond films and patterns from graphite, with potential applications from biosensors to computer chips.
Plants bask in the sun and need its light to live, but they also coat themselves in a natural sunscreen like a sunbather on the beach, protecting themselves from damaging rays. A new study examined the properties and mechanics of the molecule plants use to absorb harmful ultraviolet-B radiation, and its SPF rating would be off the charts.
Researchers are close to commercializing a new type of medical imaging technology that could diagnose cardiovascular disease by measuring ultrasound signals from molecules exposed to a fast-pulsing laser. The system takes precise 3-D images of plaques lining arteries and identifies deposits that are likely to rupture and cause heart attacks.
Research by Purdue Univ. scientist Jon Schoonmaker and his colleagues has shown that small amounts of calcium oxide can neutralize the acid in distillers grains, a commonly used alternative to corn in many livestock feed mixes. The findings are good news for beef producers hoping to provide a more nutritious, better balanced diet to their animals while keeping their feed budgets manageable.
New software algorithms have been shown to significantly reduce the time and material needed to produce objects with 3-D printers. Because the printers create objects layer-by-layer from the bottom up, this poses a challenge when printing overhanging or protruding features like a figure's outstretched arms. They must be formed using supporting structures—which are later removed—adding time and material to the process.
Several types of plastic pipes in eco-friendly green buildings in the U.S. have been found to leach chemicals into drinking water that can cause odors and sometimes exist at levels that may exceed health standards. Purdue Univ. engineering professor Andrew Whelton will detail these findings during the 2014 U.S. Green Building Council’s Greenbuild International Conference & Exposition on Oct. 24 in New Orleans.
Researchers are exploring the usefulness of ultrasound imaging to study dangerous abdominal aortic aneurysms, a bulging of the aorta that is usually fatal when it ruptures and for which there is no effective medical treatment. Abdominal aortic aneurysms are the 13th leading cause of death in the U.S., killing about 15,000 annually.
Officials at a Chicago-based startup, Sagamore-Adams Laboratories LLC, say innovations discovered in Purdue University's School of Nuclear Engineering are being commercialized to address challenges in improving radiation detection and making sealants and adhesives safer. They have developed technology that could lead to radiation sensors that cost less and provide better information than traditional sensors.
Inexpensive microrobots capable of probing and manipulating individual cells and tissue for biological research and medical applications are closer to reality with the design of a system that senses the minute forces exerted by a robot's tiny probe. Microrobots small enough to interact with cells already exist. However, there is no easy, inexpensive way to measure the small forces applied to cells by the robots, until now.
An emerging class of electrically conductive plastics called "radical polymers” may bring low-cost, transparent solar cells, flexible and lightweight batteries, and ultrathin antistatic coatings for consumer electronics and aircraft. Researchers have established the solid-state electrical properties of one such polymer, called PTMA, which is about 10 times more electrically conductive than common semiconducting polymers.
Individuals in industrial associations, educational institutions and government organizations who are interested in composites, or materials made from constituent materials with different physical or chemical properties, now have free, 24/7 access to simulation tools through an online community with offices in the Purdue Research Park.
A mysterious space within a protein critical to photosynthesis is filled with fat molecules that influence both the protein’s architecture and electrical properties, according to two recent studies. Researchers studied the atomic structure of, and electrical interactions within, the cytochrome bf complex, a protein complex central to the transport of electrons within membranes of a plant cell, a critical step in photosynthesis.
Purdue Univ. researchers have discovered the structure of the enzyme that makes cellulose, a finding that could lead to easier ways of breaking down plant materials to make biofuels and other products and materials. The research also provides the most detailed glimpse to date of the complicated process by which cellulose is produced.
Researchers are developing a robotic fabric that moves and contracts and is embedded with sensors, an approach that could lead to "active clothing" or a new class of "soft" robots. The robotic fabric, developed at Purdue Univ., is a cotton material containing sensors made of a flexible polymer and threadlike strands of a shape-memory alloy that return to a coiled shape when heated, causing the fabric to move.
Glenn Johnson, CEO of BlueVine Graphene Industries Inc., said many of the methodologies being utilized to produce graphene today are not easily scalable and require numerous post-processing steps to use it in functional applications. He said his company has developed a way to scale graphene production using a roll-to-roll chemical vapor deposition process.
Ensuring that corn absorbs the right balance of nitrogen, phosphorus and potassium is crucial to increasing global yields, a Purdue and Kansas State Univ. study finds. A review of data from more than 150 studies from the U.S. and other regions showed that high yields were linked to production systems in which corn plants took up key nutrients at specific ratios.
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