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The Lead

Nicotinoid, fungal disease team to break down termites’ defenses

May 22, 2015 7:31 am | by Natalie van Hoose, Purdue Univ. | News | Comments

Purdue Univ. research shows that a small amount of nicotinoid pesticide substantially weakens termites' ability to fight off fungal diseases, a finding that could lead to more effective methods of pest control. The study also provides clues into termites' robust defense systems and how nicotinoids affect social insects.

Findings reveal clues to functioning of mysterious “mimivirus”

May 14, 2015 4:16 pm | by Emil Venere, Purdue Univ. | News | Comments

Researchers have discovered the structure of a key protein on the surface of an unusually large...

Self-assembling, bioinstructive collagen materials for research, medical applications

April 9, 2015 7:50 am | by Emil Venere, Purdue Univ. | News | Comments

A Purdue Univ. researcher and entrepreneur is commercializing her laboratory's innovative...

Inkjet-printed liquid metal could bring wearable tech, soft robotics

April 8, 2015 7:40 am | by Emil Venere, Purdue Univ. | News | Comments

New research shows how inkjet-printing technology can be used to mass-produce electronic...

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Protein determines life or death fate of stressed cells

April 2, 2015 10:30 am | by Elizabeth K. Gardner, Purdue Univ. | News | Comments

Researchers discovered a new protein involved in the process that determines the fate of cells under stress and whether they fight to survive or sacrifice themselves for the greater good. A protein named HYPE orchestrates a response to misfolded proteins within the cell, mistakes which increase when a cell is under stress from disease or injury.

New insecticide class offers safer, more targeted mosquito control

April 2, 2015 7:37 am | by Natalie van Hoose, Purdue Univ. | News | Comments

Purdue Univ. researchers have identified a new class of chemical insecticides that could provide a safer, more selective means of controlling mosquitoes that transmit key infectious diseases such as dengue, yellow fever and elephantiasis. Known as dopamine receptor antagonists, the chemicals beat out the neurotransmitter dopamine to lock into protein receptors that span the mosquito cell membrane.

Natural nanocrystals shown to strengthen concrete

April 1, 2015 7:40 am | by Emil Venere, Purdue Univ. | News | Comments

Cellulose nanocrystals derived from industrial byproducts have been shown to increase the strength of concrete, representing a potential renewable additive to improve the ubiquitous construction material. The cellulose nanocrystals could be refined from byproducts generated in the paper, bioenergy, agriculture and pulp industries.

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Microsecond Raman imaging might probe cells, organs for disease

March 30, 2015 1:03 pm | by Emil Venere, Purdue Univ. | News | Comments

A vibrational spectroscopic imaging technology that can take images of living cells could represent an advanced medical diagnostic tool for the early detection of cancer and other diseases. High-speed spectroscopic imaging makes it possible to observe the quickly changing metabolic processes inside living cells and to image large areas of tissue, making it possible to scan an entire organ.

“Virtual nose” may reduce simulator sickness in video games

March 25, 2015 7:50 am | by Emil Venere, Purdue Univ. | News | Comments

Virtual reality games often cause simulator sickness, but new research findings point to a potential strategy to ease the affliction. Various physiological systems govern the onset of simulator sickness: a person's overall sense of touch and position, or the somatosensory system; liquid-filled tubes in the ear called the vestibular system; and the oculumotor system, or muscles that control eye movements.

New technique could bring quality-control tool for nanocomposites

March 23, 2015 4:10 pm | by Emil Venere, Purdue Univ. | News | Comments

Layered nanocomposites containing tiny structures mixed into a polymer matrix are gaining commercial use, but their complex nature can hide defects that affect performance. Now researchers have developed a system capable of detecting such defects using a "Kelvin probe" scanning method with an atomic force microscope. The ability to look below the surface of nanocomposites represents a potential new quality-control tool for industry. 

Processing tech converts packing peanuts to battery components

March 23, 2015 7:53 am | by Emil Venere, Purdue Univ. | News | Comments

Researchers have shown how to convert waste packing peanuts into high-performance carbon electrodes for rechargeable lithium-ion batteries that outperform conventional graphite electrodes, representing an environmentally friendly approach to reuse the waste.

Theoretical study suggests huge lava tubes could exist on moon

March 20, 2015 7:37 am | by Elizabeth K. Gardner, Purdue Univ. | News | Comments

Lava tubes large enough to house cities could be structurally stable on the moon, according to a theoretical study. The volcanic features are an important target for future human space exploration because they could provide shelter from cosmic radiation, meteorite impacts and temperature extremes.

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Plasmonic ceramic materials key to advances in nanophotonics

March 19, 2015 3:52 pm | by Emil Venere, Purdue Univ. | News | Comments

Progress in developing nanophotonic devices capable of withstanding high temperatures and harsh conditions for applications including data storage, sensing, health care and energy will depend on the research community and industry adopting new "plasmonic ceramic" materials, according to a commentary in Science.

New trigger of cellular self-destruction identified

March 17, 2015 8:03 am | by Elizabeth Gardner, Purdue Univ. | News | Comments

Researchers have identified a bacterial protein that triggers a self-inflicted cell death pathway in immune system cells and could lead to a better understanding of an important cellular structure. The protein initiates a cascade of events that leads the lysosome to open holes in its membrane and release enzymes that destroy the cell.

Study yields insights into how plant cells grow

March 12, 2015 8:06 am | by Natalie van Hoose, Purdue Univ. | News | Comments

A study by Purdue Univ. plant scientists and Univ. of Nebraska-Lincoln engineers advances our understanding of how plants control their shape and development at the cellular level. Their findings could help researchers engineer better cotton fibers, improve plant defense against insects, alter plant architecture and toughen root response to drought.

Simulations provide new insight into emerging nanoelectronic device

March 6, 2015 7:50 am | by Emil Venere, Purdue Univ. | News | Comments

Researchers have used an advanced model to simulate in unprecedented detail the workings of "resistance-switching cells" that might replace conventional memory for electronics applications, with the potential to bring faster and higher capacity computer memory while consuming less energy. These electromechanical "metallization cells" rapidly switch from high resistance to low resistance.

Sub-micrometer carbon spheres reduce engine friction as oil additive

March 5, 2015 8:31 am | by Emil Venere, Purdue Univ. | News | Comments

Tiny, perfectly smooth carbon spheres added to motor oil have been shown to reduce friction and wear typically seen in engines by as much as 25%, suggesting a similar enhancement in fuel economy. The researchers also have shown how to potentially mass-produce the spheres, making them hundreds of times faster than previously possible using ultrasound to speed chemical reactions in manufacturing.

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Genome reveals how Hessian fly causes galls in wheat

March 4, 2015 8:14 am | by Natalie van Hoose, Purdue Univ. | News | Comments

A team of researchers from 26 institutions around the world has sequenced the Hessian fly genome, shedding light on how the insect creates growth-stunting galls in wheat. Hessian fly larvae can destroy entire wheat fields by injecting seedlings with potent saliva that "hijacks" the plants' biochemistry, irreversibly halting development and forcing the seedlings to produce a leaky tissue that contains nutrients for the larvae.

Economic models provide insights into global sustainability challenges

February 27, 2015 7:40 am | by Natalie van Hoose, Purdue Univ. | News | Comments

Using models that blend global economics, geography, ecology and environmental sciences is essential to understanding how changes in trade and natural systems in one part of the world affect those in another, a review concludes. An interdisciplinary team of experts determined how systems integration could shed insights on how activities in one part of the world can have significant impacts on distant regions.

Microfluidics enables production of shape-controllable microgels

February 10, 2015 10:41 am | by Emil Venere, Purdue Univ. | News | Comments

A new, relatively simple process makes it possible to create biocompatible particles called shape-controllable microgels that could be custom designed for specific roles such as drug delivery vehicles, tissue engineering building blocks and biomedical research. The particles are made of two distinctly different materials: polymers called polyNIPAAm and sodium alginate, used in drug delivery.

Chances of saving with solar energy greater for Indiana farms than homes

February 6, 2015 8:14 am | by Natalie van Hoose, Purdue Univ. | News | Comments

The probability of saving money by using solar energy rather than standard grid electricity is 92% for Indiana farm businesses and about 50% for homes, Purdue Univ. energy economists find. While current energy policies play key roles in providing incentives for the use of solar energy in Indiana, businesses have an additional cost-saving option not available to residences: Businesses can deduct their investment in solar from their revenues.

Drug combo suppresses growth of late-stage prostate cancer tumors

January 28, 2015 8:31 am | by Natalie van Hoose, Purdue Univ. | News | Comments

Low doses of metformin, a widely used diabetes medication and a gene inhibitor known as BI2536 can successfully halt the growth of late-stage prostate cancer tumors, a Purdue Univ. study finds. Prostate cancer causes the second-highest number of cancer-related deaths in men in the U.S., and methods of treating advanced prostate cancer are limited.

Research aims to improve lithium-based batteries

January 21, 2015 8:31 am | by Emil Venere, Purdue Univ. | News | Comments

Research probing the complex science behind the formation of "dendrites" that cause lithium-ion batteries to fail could bring safer, longer-lasting batteries capable of being charged within minutes instead of hours. The dendrites form on anode electrodes and may continue to grow until causing an internal short circuit, which results in battery failure and possible fire.

System encourages creativity, makes robot design fun

January 20, 2015 8:01 am | by Emil Venere, Purdue Univ. | News | Comments

A new cardboard-robotic toolkit allows children to create custom robots they control wirelessly with hand gestures without formal education in programming or electronics. The system, called HandiMate, uses motorized "joint modules" equipped with wireless communicators and microcontrollers. Children create robots by using Velcro strips to attach the modules to any number of everyday materials and objects.

Single-photon emission enhancement

January 14, 2015 8:01 am | by Emil Venere, Purdue Univ. | News | Comments

Researchers have demonstrated a new way to enhance the emission of single photons by using "hyperbolic metamaterials," a step toward creating devices in work aimed at developing quantum computers and communications technologies. Optical metamaterials harness clouds of electrons called surface plasmons to manipulate and control light.

Research suggests approach to treat virus causing respiratory illness in children

January 5, 2015 8:01 am | by Emil Venere, Purdue Univ. | News | Comments

New research findings point toward a class of compounds that could be effective in combating infections caused by enterovirus D68, which has stricken children with serious respiratory infections in the U.S. and elsewhere. The researchers used x-ray crystallography to learn the precise structure of the original strain of EV-D68 on its own and when bound to an anti-viral compound called "pleconaril."

New conversion process turns biomass “waste” into lucrative chemical products

December 17, 2014 2:58 pm | by Elizabeth K. Gardner, Purdue Univ. | Videos | Comments

A new catalytic process is able to convert what was once considered biomass waste into lucrative chemical products that can be used in fragrances, flavorings or to create high-octane fuel. A team of researchers from Purdue Univ.'s Center for Direct Catalytic Conversion of Biomass to Biofuels, or C3Bio, has developed a process that uses a chemical catalyst and heat to spur reactions that convert lignin into valuable chemical commodities.

Germanium comes home to Purdue for semiconductor milestone

December 8, 2014 4:26 pm | by Emil Venere, Purdue Univ. | News | Comments

A laboratory at Purdue Univ. provided a critical part of the world's first transistor in 1947—the purified germanium semiconductor—and now researchers here are on the forefront of a new germanium milestone. The team has created the first modern germanium circuit—a complementary metal–oxide–semiconductor (CMOS) device—using germanium as the semiconductor instead of silicon.

Purdue, GE collaborate on advanced manufacturing

December 5, 2014 8:32 am | by Judith Barra Austin, Purdue Univ. | News | Comments

Purdue Univ. announced that GE Global Research will invest up to $10 million in a five-year partnership focused on R&D in advanced manufacturing. The GE/Purdue Partnership in Research and Innovation in Advanced Manufacturing will push a new era in manufacturing, promoting technologies that enable the digitization, decentralization and democratization of manufacturing to lower cost, improve speed and drive innovation.

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