A team of researchers has created a new implantable drug-delivery system using nanowires that can be wirelessly controlled. The nanowires respond to an electromagnetic field generated by a separate device, which can be used to control the release of a preloaded drug. The system eliminates tubes and wires required by other implantable devices that can lead to infection and other complications.
A Purdue Univ.-led team of researchers studying the Middle East Respiratory Syndrome, or MERS,...
Purdue Univ. research shows that a small amount of nicotinoid pesticide substantially weakens...
Researchers have discovered the structure of a key protein on the surface of an unusually large...
A Purdue Univ. researcher and entrepreneur is commercializing her laboratory's innovative collagen formulations that self-assemble or polymerize to form fibrils that resemble those found in the body's tissues. These collagen building blocks can be used to create customized 3-D tissue and organs outside the body to support basic biological research, drug discovery and chemical toxicity testing.
New research shows how inkjet-printing technology can be used to mass-produce electronic circuits made of liquid-metal alloys for "soft robots" and flexible electronics. Elastic technologies could make possible a new class of pliable robots and stretchable garments that people might wear to interact with computers or for therapeutic purposes.
Researchers discovered a new protein involved in the process that determines the fate of cells under stress and whether they fight to survive or sacrifice themselves for the greater good. A protein named HYPE orchestrates a response to misfolded proteins within the cell, mistakes which increase when a cell is under stress from disease or injury.
Purdue Univ. researchers have identified a new class of chemical insecticides that could provide a safer, more selective means of controlling mosquitoes that transmit key infectious diseases such as dengue, yellow fever and elephantiasis. Known as dopamine receptor antagonists, the chemicals beat out the neurotransmitter dopamine to lock into protein receptors that span the mosquito cell membrane.
Cellulose nanocrystals derived from industrial byproducts have been shown to increase the strength of concrete, representing a potential renewable additive to improve the ubiquitous construction material. The cellulose nanocrystals could be refined from byproducts generated in the paper, bioenergy, agriculture and pulp industries.
A vibrational spectroscopic imaging technology that can take images of living cells could represent an advanced medical diagnostic tool for the early detection of cancer and other diseases. High-speed spectroscopic imaging makes it possible to observe the quickly changing metabolic processes inside living cells and to image large areas of tissue, making it possible to scan an entire organ.
Virtual reality games often cause simulator sickness, but new research findings point to a potential strategy to ease the affliction. Various physiological systems govern the onset of simulator sickness: a person's overall sense of touch and position, or the somatosensory system; liquid-filled tubes in the ear called the vestibular system; and the oculumotor system, or muscles that control eye movements.
Layered nanocomposites containing tiny structures mixed into a polymer matrix are gaining commercial use, but their complex nature can hide defects that affect performance. Now researchers have developed a system capable of detecting such defects using a "Kelvin probe" scanning method with an atomic force microscope. The ability to look below the surface of nanocomposites represents a potential new quality-control tool for industry.
Researchers have shown how to convert waste packing peanuts into high-performance carbon electrodes for rechargeable lithium-ion batteries that outperform conventional graphite electrodes, representing an environmentally friendly approach to reuse the waste.
Lava tubes large enough to house cities could be structurally stable on the moon, according to a theoretical study. The volcanic features are an important target for future human space exploration because they could provide shelter from cosmic radiation, meteorite impacts and temperature extremes.
Progress in developing nanophotonic devices capable of withstanding high temperatures and harsh conditions for applications including data storage, sensing, health care and energy will depend on the research community and industry adopting new "plasmonic ceramic" materials, according to a commentary in Science.
Researchers have identified a bacterial protein that triggers a self-inflicted cell death pathway in immune system cells and could lead to a better understanding of an important cellular structure. The protein initiates a cascade of events that leads the lysosome to open holes in its membrane and release enzymes that destroy the cell.
A study by Purdue Univ. plant scientists and Univ. of Nebraska-Lincoln engineers advances our understanding of how plants control their shape and development at the cellular level. Their findings could help researchers engineer better cotton fibers, improve plant defense against insects, alter plant architecture and toughen root response to drought.
Researchers have used an advanced model to simulate in unprecedented detail the workings of "resistance-switching cells" that might replace conventional memory for electronics applications, with the potential to bring faster and higher capacity computer memory while consuming less energy. These electromechanical "metallization cells" rapidly switch from high resistance to low resistance.
Tiny, perfectly smooth carbon spheres added to motor oil have been shown to reduce friction and wear typically seen in engines by as much as 25%, suggesting a similar enhancement in fuel economy. The researchers also have shown how to potentially mass-produce the spheres, making them hundreds of times faster than previously possible using ultrasound to speed chemical reactions in manufacturing.
A team of researchers from 26 institutions around the world has sequenced the Hessian fly genome, shedding light on how the insect creates growth-stunting galls in wheat. Hessian fly larvae can destroy entire wheat fields by injecting seedlings with potent saliva that "hijacks" the plants' biochemistry, irreversibly halting development and forcing the seedlings to produce a leaky tissue that contains nutrients for the larvae.
Using models that blend global economics, geography, ecology and environmental sciences is essential to understanding how changes in trade and natural systems in one part of the world affect those in another, a review concludes. An interdisciplinary team of experts determined how systems integration could shed insights on how activities in one part of the world can have significant impacts on distant regions.
A new, relatively simple process makes it possible to create biocompatible particles called shape-controllable microgels that could be custom designed for specific roles such as drug delivery vehicles, tissue engineering building blocks and biomedical research. The particles are made of two distinctly different materials: polymers called polyNIPAAm and sodium alginate, used in drug delivery.
The probability of saving money by using solar energy rather than standard grid electricity is 92% for Indiana farm businesses and about 50% for homes, Purdue Univ. energy economists find. While current energy policies play key roles in providing incentives for the use of solar energy in Indiana, businesses have an additional cost-saving option not available to residences: Businesses can deduct their investment in solar from their revenues.
Low doses of metformin, a widely used diabetes medication and a gene inhibitor known as BI2536 can successfully halt the growth of late-stage prostate cancer tumors, a Purdue Univ. study finds. Prostate cancer causes the second-highest number of cancer-related deaths in men in the U.S., and methods of treating advanced prostate cancer are limited.
Research probing the complex science behind the formation of "dendrites" that cause lithium-ion batteries to fail could bring safer, longer-lasting batteries capable of being charged within minutes instead of hours. The dendrites form on anode electrodes and may continue to grow until causing an internal short circuit, which results in battery failure and possible fire.
A new cardboard-robotic toolkit allows children to create custom robots they control wirelessly with hand gestures without formal education in programming or electronics. The system, called HandiMate, uses motorized "joint modules" equipped with wireless communicators and microcontrollers. Children create robots by using Velcro strips to attach the modules to any number of everyday materials and objects.
Researchers have demonstrated a new way to enhance the emission of single photons by using "hyperbolic metamaterials," a step toward creating devices in work aimed at developing quantum computers and communications technologies. Optical metamaterials harness clouds of electrons called surface plasmons to manipulate and control light.
New research findings point toward a class of compounds that could be effective in combating infections caused by enterovirus D68, which has stricken children with serious respiratory infections in the U.S. and elsewhere. The researchers used x-ray crystallography to learn the precise structure of the original strain of EV-D68 on its own and when bound to an anti-viral compound called "pleconaril."
A new catalytic process is able to convert what was once considered biomass waste into lucrative chemical products that can be used in fragrances, flavorings or to create high-octane fuel. A team of researchers from Purdue Univ.'s Center for Direct Catalytic Conversion of Biomass to Biofuels, or C3Bio, has developed a process that uses a chemical catalyst and heat to spur reactions that convert lignin into valuable chemical commodities.
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