Our DNA is under constant attack from many sources. Fortunately, cells have several major DNA repair systems that can fix this damage, which may lead to diseases if not mended. A team of researchers has developed a test that can rapidly assess several DNA repair systems, which could help determine individuals’ risk of developing cancer and help doctors predict how a given patient will respond to chemotherapy drugs.
Unlike healthy cells, cancer cells thrive when deprived of oxygen. Tumors in low-oxygen environments tend to be more resistant to therapy and spread more aggressively to other parts of the body. Measuring tumors’ oxygen levels could help doctors make decisions about treatments, but there’s currently no way to make such measurements. However, a new sensor developed at Massachusetts Institute of Technology could change that.
These days, Hugh Herr, an assoc. prof. of media arts and sciences at Massachusetts Institute of Technology, gets about 100 emails daily from people across the world interested in his bionic limbs. Messages pour in from amputees seeking prostheses and from media outlets pursuing interviews. Then there are students looking to join Herr’s research group.
When an earthquake and tsunami struck the Fukushima Daiichi nuclear plant complex in 2011, neither the quake nor the inundation caused the ensuing contamination. Rather, it was the aftereffects—specifically, the lack of cooling for the reactor cores, due to a shutdown of all power at the station—that caused most of the harm. A new design for nuclear plants built on floating platforms could help avoid such consequences in the future.
A quasiparticle called an exciton has been understood theoretically for decades. But exciton movement within materials has never been directly observed. Now scientists have achieved that feat, imaging excitons’ motions directly. This could enable research leading to significant advances in electronics, they say, as well as a better understanding of natural energy-transfer processes, such as photosynthesis.
Since the discovery of the Antarctic ozone hole, scientists, policymakers and the public have wondered whether we might someday see a similarly extreme depletion of ozone over the Arctic. But a new Massachusetts Institute of Technology study finds some cause for optimism: Ozone levels in the Arctic haven’t yet sunk to the extreme lows seen in Antarctica, because international efforts to limit ozone-depleting chemicals have been successful.
Delivering chemotherapy drugs in nanoparticle form could help reduce side effects by targeting the drugs directly to the tumors. In recent years, scientists have developed nanoparticles that deliver one or two chemotherapy drugs, but it has been difficult to design particles that can carry any more than that in a precise ratio. Now Massachusetts Institute of Technology chemists have devised a new way to build such nanoparticles.
It’s an obvious truism, but one that may soon be outdated: The problem with solar power is that sometimes the sun doesn’t shine. Now a team at Massachusetts Institute of Technology and Harvard Univ. has come up with an ingenious workaround: a material that can absorb the sun’s heat and store that energy in chemical form, ready to be released again on demand.
Picking out a face in the crowd is a complicated task: Your brain has to retrieve the memory of the face you’re seeking, then hold it in place while scanning the crowd, paying special attention to finding a match. A new study reveals how the brain achieves this type of focused attention on faces or other objects.
Thousands of consumer products contain nanoparticles added by manufacturers to improve texture, kill microbes or enhance shelf life, among other purposes. However, several studies have shown that some of these engineered nanoparticles can be toxic to cells. A new study from Massachusetts Institute of Technology and the Harvard School of Public Health suggests that certain nanoparticles can also harm DNA.
Using a laser to place individual rubidium atoms near the surface of a lattice of light, scientists at Massachusetts Institute of Technology and Harvard Univ. have developed a new method for connecting particles—one that could help in the development of powerful quantum computing systems.
The next time you feel a sneeze coming on, raise your elbow to cover up that multiphase turbulent buoyant cloud you’re about to expel. That’s right: A novel study by Massachusetts Institute of Technology researchers shows that coughs and sneezes have associated gas clouds that keep their potentially infectious droplets aloft over much greater distances than previously realized.
Researchers are working on a new algorithm that could make re-identification much easier for computers by identifying the major orientations in 3-D scenes. The same algorithm could also simplify the problem of scene understanding, one of the central challenges in computer vision research.
Economics has a “law of one price,” which states that identical goods should, in theory, sell for identical prices or else markets will even out the differences. Empirical work on the topic, however, has produced little evidence in support of this “law”. Now, a newly published paper presents evidence of a strong convergence of prices within the Eurozone, the region of European countries sharing a common currency.
Fossil remains show that sometime around 252 million years ago, about 90% of all species on Earth were suddenly wiped out in what was the largest of this planet’s five known mass extinctions. But pinpointing the culprit has been difficult, and controversial. Now, a team of Massachusetts Institute of Technology researchers may have found enough evidence to convict the guilty parties, but you’ll need a microscope to see the killers.
Using a new gene-editing system based on bacterial proteins, Massachusetts Institute of Technology researchers have cured mice of a rare liver disorder caused by a single genetic mutation. The findings offer the first evidence that this gene-editing technique, known as CRISPR, can reverse disease symptoms in living animals.
The shells of a sea creature, the mollusk Placuna placenta, are not only exceptionally tough, but also clear enough to read through. Now, researchers at Massachusetts Institute of Technology have analyzed these shells to determine exactly why they are so resistant to penetration and damage; even though they are 99% calcite, a weak, brittle mineral.
Light waves can be defined by three fundamental characteristics: their color (or wavelength), polarization and direction. While it has long been possible to selectively filter light according to its color or polarization, selectivity based on the direction of propagation has remained elusive. Until now.
The Atlantic razor clam uses very little energy to burrow into undersea soil at high speed. Now a detailed insight into how the animal digs has led to the development of a robotic clam that can perform the same trick. The device, known as “RoboClam,” could be used to dig itself into the ground to bury anchors or destroy underwater mines.
Doctors commonly use MRI to diagnose tumors, damage from stroke and many other medical conditions. Neuroscientists also rely on it as a research tool for identifying parts of the brain that carry out different cognitive functions. Now, a team of biological engineers at Massachusetts Institute of Technology is trying to adapt MRI to a much smaller scale.
Massachusetts Institute of Technology engineers have coaxed bacterial cells to produce biofilms that can incorporate non-living materials, such as gold nanoparticles and quantum dots. These “living materials” combine the advantages of live cells, which respond to their environment and produce complex biological molecules, with the benefits of nonliving materials, which add functions such as conducting electricity or emitting light.
In 2007, Massachusetts Institute of Technology scientists developed a type of microscopy that allowed them to detail the interior of a living cell in 3-D, without adding any fluorescent markers or other labels. This technique also revealed key properties, such as the cells’ density. Now the researchers have adapted that method so they can image cells as they flow through a tiny microfluidic channel.
Small protein fragments, also called peptides, are promising as drugs because they can be designed for very specific functions inside living cells. Insulin and the HIV drug Fuzeon are some of the earliest successful examples, and peptide drugs are expected to become a $25 billion market by 2018. However, a major bottleneck has prevented peptide drugs from reaching their full potential.
Even in a crowded room full of background noise, the human ear is remarkably adept at tuning in to a single voice—a feat that has proved remarkably difficult for computers to match. A new analysis of the underlying mechanisms, conducted by researchers at Massachusetts Institute of Technology, has provided insights that could ultimately lead to better machine hearing, and perhaps to better hearing aids as well.
Consider the nearest water surface: a half-full glass on your desk, a puddle outside your window or a lake across town. All of these surfaces represent liquid-vapor interfaces, where liquid meets air. Molecules of water vapor constantly collide with these liquid surfaces: Some make it through the surface and condense, while others simply bounce off.